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5F8G
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BU of 5f8g by Molmil
Enterovirus 71 Polymerase Elongation Complex (C1S1 Form)
Descriptor: Genome polyprotein, RNA (35-MER), RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*AP*GP*A)-3'), ...
Authors:Shu, B, Gong, P.
Deposit date:2015-12-09
Release date:2016-06-22
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Structural basis of viral RNA-dependent RNA polymerase catalysis and translocation
Proc.Natl.Acad.Sci.USA, 113, 2016
8E1L
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BU of 8e1l by Molmil
Crystal structure of photoactive yellow protein (PYP); F96oCNF M100N construct
Descriptor: 4'-HYDROXYCINNAMIC ACID, Photoactive yellow protein
Authors:Kirsh, J.M, Weaver, J.B, Boxer, S.G.
Deposit date:2022-08-10
Release date:2022-08-24
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Protic and Aprotic Interactions Systematically Perturbed and Mapped via MD and IR Spectroscopy
To Be Published
8DZU
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BU of 8dzu by Molmil
Crystal structure of photoactive yellow protein (PYP); F96oCNF M100H construct
Descriptor: 4'-HYDROXYCINNAMIC ACID, Photoactive yellow protein
Authors:Kirsh, J.M, Weaver, J.B, Boxer, S.G.
Deposit date:2022-08-08
Release date:2022-08-24
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.04 Å)
Cite:Protic and Aprotic Interactions Systematically Perturbed and Mapped via MD and IR Spectroscopy
To Be Published
6ZQD
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BU of 6zqd by Molmil
Cryo-EM structure of the 90S pre-ribosome from Saccharomyces cerevisiae, state Post-A1
Descriptor: 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ...
Authors:Cheng, J, Lau, B, Venuta, G.L, Berninghausen, O, Hurt, E, Beckmann, R.
Deposit date:2020-07-09
Release date:2020-09-23
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:90 S pre-ribosome transformation into the primordial 40 S subunit.
Science, 369, 2020
5J0H
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BU of 5j0h by Molmil
De novo design of protein homo-oligomers with modular hydrogen bond network-mediated specificity
Descriptor: Design construct 2L6HC3_13
Authors:Sankaran, B, Zwart, P.H, Pereira, J.H, Baker, D, Boyken, S, Chen, Z, Groves, B, Langan, R.A, Oberdorfer, G, Ford, A, Gilmore, J, Xu, C, DiMaio, F, Seelig, G.
Deposit date:2016-03-28
Release date:2016-05-25
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:De novo design of protein homo-oligomers with modular hydrogen-bond network-mediated specificity.
Science, 352, 2016
8SKS
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BU of 8sks by Molmil
human liver mitochondrial Superoxide dismutase [Mn]
Descriptor: MANGANESE (II) ION, Superoxide dismutase [Mn], mitochondrial
Authors:Zhang, Z, Tringides, M.
Deposit date:2023-04-20
Release date:2024-02-21
Method:ELECTRON MICROSCOPY (2.91 Å)
Cite:High-Resolution Structural Proteomics of Mitochondria Using the 'Build and Retrieve' Methodology.
Mol.Cell Proteomics, 22, 2023
5Y4T
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BU of 5y4t by Molmil
Crystal structure of Trx domain of Grx3 from Saccharomyces cerevisiae
Descriptor: GLYCEROL, Glutaredoxin
Authors:Chi, C.B, Tang, Y.J, Zhang, J.H, Dai, Y.N, Abdalla, M, Chen, Y.X, Zhou, C.Z.
Deposit date:2017-08-05
Release date:2018-08-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural and Biochemical Insights into the Multiple Functions of Yeast Grx3.
J.Mol.Biol., 430, 2018
5F8N
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BU of 5f8n by Molmil
Enterovirus 71 Polymerase Elongation Complex (C3S6 Form)
Descriptor: GLYCEROL, Genome polyprotein, PYROPHOSPHATE 2-, ...
Authors:Shu, B, Gong, P.
Deposit date:2015-12-09
Release date:2016-06-22
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.484 Å)
Cite:Structural basis of viral RNA-dependent RNA polymerase catalysis and translocation
Proc.Natl.Acad.Sci.USA, 113, 2016
3H08
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BU of 3h08 by Molmil
Crystal structure of the Ribonuclease H1 from Chlorobium tepidum
Descriptor: MAGNESIUM ION, Rnh (Ribonuclease H)
Authors:Ratcliff, K, Corn, J, Marqusee, S.
Deposit date:2009-04-08
Release date:2009-05-12
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure, stability, and folding of ribonuclease H1 from the moderately thermophilic chlorobium tepidum: comparison with thermophilic and mesophilic homologues.
Biochemistry, 48, 2009
5J10
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BU of 5j10 by Molmil
De novo design of protein homo-oligomers with modular hydrogen bond network-mediated specificity
Descriptor: peptide design 2L4HC2_24
Authors:Sankaran, B, Zwart, P.H, Pereira, J.H, Baker, D, Boyken, S, Chen, Z, Groves, B, Langan, R.A, Oberdorfer, G, Ford, A, Gilmore, J, Xu, C, DiMaio, F, Seelig, G.
Deposit date:2016-03-28
Release date:2016-05-25
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:De novo design of protein homo-oligomers with modular hydrogen-bond network-mediated specificity.
Science, 352, 2016
1WE9
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BU of 1we9 by Molmil
Solution structure of PHD domain in nucleic acid binding protein-like NP_197993
Descriptor: PHD finger family protein, ZINC ION
Authors:He, F, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2004-05-24
Release date:2004-11-24
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of PHD domain in nucleic acid binding protein-like NP_197993
To be Published
6XT9
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BU of 6xt9 by Molmil
Subunits BBS 1,4,8,9,18 of the human BBSome complex
Descriptor: BBSome-interacting protein 1, Bardet-Biedl syndrome 1 protein, Bardet-Biedl syndrome 4 protein, ...
Authors:Klink, B.U, Raunser, S, Gatsogiannis, C.
Deposit date:2020-01-15
Release date:2020-01-29
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure of the human BBSome core complex.
Elife, 9, 2020
7QWL
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BU of 7qwl by Molmil
TMEM106B filaments with Fold IIb from Multiple system atrophy (case 19)
Descriptor: Transmembrane protein 106B
Authors:Lovestam, S, Schweighauser, M, Scheres, S.H.W.
Deposit date:2022-01-25
Release date:2022-03-09
Last modified:2022-05-25
Method:ELECTRON MICROSCOPY (3.47 Å)
Cite:Age-dependent formation of TMEM106B amyloid filaments in human brains.
Nature, 605, 2022
5UVF
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BU of 5uvf by Molmil
Crystal Structure of the Human vaccinia-related kinase bound to BI-D1870
Descriptor: (7S)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimethyl-8-(3-methylbutyl)-7,8-dihydropteridin-6(5H)-one, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Counago, R.M, Bountra, C, Arruda, P, Edwards, A.M, Gileadi, O, Structural Genomics Consortium (SGC)
Deposit date:2017-02-20
Release date:2017-03-22
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural characterization of human Vaccinia-Related Kinases (VRK) bound to small-molecule inhibitors identifies different P-loop conformations.
Sci Rep, 7, 2017
7QVC
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BU of 7qvc by Molmil
TMEM106B filaments with Fold I from Alzheimer's disease (case 1)
Descriptor: Transmembrane protein 106B
Authors:Lovestam, S, Schweighauser, M, Scheres, S.H.W.
Deposit date:2022-01-21
Release date:2022-03-09
Last modified:2022-05-25
Method:ELECTRON MICROSCOPY (2.64 Å)
Cite:Age-dependent formation of TMEM106B amyloid filaments in human brains.
Nature, 605, 2022
7QVF
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BU of 7qvf by Molmil
TMEM106B filaments with Fold I-d from Multiple system atrophy (case 18)
Descriptor: Transmembrane protein 106B
Authors:Lovestam, S, Schweighauser, M, Scheres, S.H.W.
Deposit date:2022-01-21
Release date:2022-03-09
Last modified:2022-05-25
Method:ELECTRON MICROSCOPY (3.64 Å)
Cite:Age-dependent formation of TMEM106B amyloid filaments in human brains.
Nature, 605, 2022
7QWG
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BU of 7qwg by Molmil
TMEM106B filaments with Fold IIa from Multiple system atrophy (case 19)
Descriptor: Transmembrane protein 106B
Authors:Lovestam, S, Schweighauser, M, Scheres, S.H.W.
Deposit date:2022-01-25
Release date:2022-03-09
Last modified:2022-05-25
Method:ELECTRON MICROSCOPY (3.38 Å)
Cite:Age-dependent formation of TMEM106B amyloid filaments in human brains.
Nature, 605, 2022
6XZ5
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BU of 6xz5 by Molmil
RovC - regulator of virulence interconnected with the Csr system
Descriptor: SULFATE ION, Uncharacterized protein,RovC,Uncharacterized protein
Authors:Sadana, P, Scrima, A.
Deposit date:2020-02-02
Release date:2020-09-16
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:RovC - a novel type of hexameric transcriptional activator promoting type VI secretion gene expression.
Plos Pathog., 16, 2020
6XZC
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BU of 6xzc by Molmil
CryoEM structure of the ring-shaped virulence factor EspB from Mycobacterium tuberculosis
Descriptor: ESX-1 secretion-associated protein EspB
Authors:Piton, J, Pojer, F, Wakatsuki, S, Gati, C, Cole, S.T.
Deposit date:2020-02-03
Release date:2020-06-17
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.37 Å)
Cite:High resolution CryoEM structure of the ring-shaped virulence factor EspB fromMycobacterium tuberculosis.
J Struct Biol X, 4, 2020
8JED
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BU of 8jed by Molmil
Crystal structure of mRNA cap (guanine-N7) methyltransferase E12 subunit from monkeypox virus and discovery of its inhibitors
Descriptor: mRNA-capping enzyme regulatory subunit OPG124
Authors:Wang, D, Zhao, R, Shu, W, Hu, W, Wang, M, Cao, J, Zhou, X.
Deposit date:2023-05-15
Release date:2023-12-06
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Crystal structure of mRNA cap (guanine-N7) methyltransferase E12 subunit from monkeypox virus and discovery of its inhibitors.
Int.J.Biol.Macromol., 253, 2023
7S9U
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BU of 7s9u by Molmil
44SR3C ribosomal particle
Descriptor: 50S ribosomal protein L13, 50S ribosomal protein L14, 50S ribosomal protein L15, ...
Authors:Ortega, J, Seffouh, A.
Deposit date:2021-09-21
Release date:2022-03-02
Last modified:2022-11-16
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:RbgA ensures the correct timing in the maturation of the 50S subunits functional sites.
Nucleic Acids Res., 50, 2022
7SAE
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BU of 7sae by Molmil
44SR70P Class1 ribosomal particle
Descriptor: 50S ribosomal protein L13, 50S ribosomal protein L14, 50S ribosomal protein L15, ...
Authors:Ortega, J, Seffouh, A.
Deposit date:2021-09-22
Release date:2022-03-02
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3 Å)
Cite:RbgA ensures the correct timing in the maturation of the 50S subunits functional sites.
Nucleic Acids Res., 50, 2022
7SAQ
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BU of 7saq by Molmil
Cryo-EM structure of TMEM106B fibrils extracted from a FTLD-TDP patient, polymorph 1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Transmembrane protein 106B
Authors:Cao, Q, Jiang, Y, Sawaya, M.R, Eisenberg, D.S.
Deposit date:2021-09-23
Release date:2022-03-09
Last modified:2022-05-25
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Amyloid fibrils in FTLD-TDP are composed of TMEM106B and not TDP-43.
Nature, 605, 2022
3SCF
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BU of 3scf by Molmil
Fe(II)-HppE with S-HPP and NO
Descriptor: (S)-2-HYDROXYPROPYLPHOSPHONIC ACID, Epoxidase, FE (II) ION, ...
Authors:Drennan, C.L.
Deposit date:2011-06-07
Release date:2011-07-06
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural basis of regiospecificity of a mononuclear iron enzyme in antibiotic fosfomycin biosynthesis.
J.Am.Chem.Soc., 133, 2011
5F6D
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BU of 5f6d by Molmil
Crystal structure of Ubc9 (K48A/K49A/E54A) complexed with Fragment 6
Descriptor: 6~{H}-benzo[c][1,2]benzothiazine 5,5-dioxide, SUMO-conjugating enzyme UBC9
Authors:Lountos, G.T, Hewitt, W.M, Zlotkowski, K, Dahlhauser, S, Saunders, L.B, Needle, D, Tropea, J.E, Zhan, C, Wei, G, Ma, B, Nussinov, R, Schneekloth, J.S.Jr, Waugh, D.S.
Deposit date:2015-12-05
Release date:2016-04-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.553 Å)
Cite:Insights Into the Allosteric Inhibition of the SUMO E2 Enzyme Ubc9.
Angew.Chem.Int.Ed.Engl., 55, 2016

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