PDB: 5515 resultsInfo pagesStatus searchChemie searchBIRD

---

7TBN	LOV2-DARPIN fusion : D11 Descriptor: CARBONATE ION, D11 LOV2-DARPin fusion, GLYCEROL Authors: Mittl, P. Deposit date: 2021-12-22 Release date: 2023-07-05 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.76 Å) Cite: LOV2-DARPIN fusion : D11 To Be Published
7TBO	LOV2-DARPIN fusion : D12 Descriptor: D12 LOV2-DARPin fusion, GLYCEROL Authors: Mittl, P. Deposit date: 2021-12-22 Release date: 2023-07-05 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.32 Å) Cite: LOV2-DARPIN fusion : D12 To Be Published
7TCD	LOV2-DARPIN fusion: D13 Descriptor: CHLORIDE ION, D13 LOV2-DARPin fusion, FLAVIN MONONUCLEOTIDE, ... Authors: Mittl, P. Deposit date: 2021-12-23 Release date: 2023-07-05 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.7 Å) Cite: LOV2-DARPIN fusion: D13 To Be Published
7TBQ	LOV2-DARPIN fusion : D7 Descriptor: CHLORIDE ION, D7 LOV2-DARPin fusion, FLAVIN MONONUCLEOTIDE, ... Authors: Mittl, P. Deposit date: 2021-12-22 Release date: 2023-07-05 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.678 Å) Cite: LOV2-DARPIN fusion : D7 To Be Published
1T6W	RATIONAL DESIGN OF A CALCIUM-BINDING ADHESION PROTEIN NMR, 20 STRUCTURES Descriptor: CALCIUM ION, hypothetical protein XP_346638 Authors: Yang, W, Wilkins, A.L, Ye, Y, Liu, Z.-R, Urbauer, J.L, Kearney, A, van der Merwe, P.A, Yang, J.J. Deposit date: 2004-05-07 Release date: 2005-02-15 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Design of a calcium-binding protein with desired structure in a cell adhesion molecule. J.Am.Chem.Soc., 127, 2005
1STO	CRYSTAL STRUCTURE OF OROTATE PHOSPHORIBOSYLTRANSFERASE Descriptor: HYDROXIDE ION, OROTATE PHOSPHORIBOSYLTRANSFERASE, OROTIDINE-5'-MONOPHOSPHATE Authors: Scapin, G, Grubmeyer, C, Sacchettini, J.C. Deposit date: 1993-12-20 Release date: 1994-05-31 Last modified: 2019-08-14 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Crystal structure of orotate phosphoribosyltransferase. Biochemistry, 33, 1994
1TJB	Crystal Structure of a High Affinity Lanthanide-Binding Peptide (LBT) Descriptor: CHLORIDE ION, Lanthanide-Binding Peptide, TERBIUM(III) ION Authors: Nitz, M, Sherawat, M, Franz, K.J, Peisach, E, Allen, K.N, Imperiali, B. Deposit date: 2004-06-03 Release date: 2004-08-03 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural Origin of the High Affinity of a Chemically Evolved Lanthanide-Binding Peptide Angew.Chem.Int.Ed.Engl., 43, 2004
6Q1W	Coiled-coil Trimer with Glu:Val:Lys Triad Descriptor: Coiled-coil Trimer with Glu:Val:Lys Triad Authors: Smith, M.S, Stern, K.L, Billings, W.M, Price, J.L. Deposit date: 2019-08-06 Release date: 2020-04-29 Last modified: 2020-05-20 Method: X-RAY DIFFRACTION (1.498 Å) Cite: Context-Dependent Stabilizing Interactions among Solvent-Exposed Residues along the Surface of a Trimeric Helix Bundle. Biochemistry, 59, 2020
7Q3J	Computationally designed thioredoxin subjected to stability optimizing mutations. Descriptor: GLYCEROL, MM9 Authors: Norrild, R.K, Johansson, K.E, O'Shea, C, Lindorff-Larsen, K, Winther, J.R, Morth, J.P. Deposit date: 2021-10-27 Release date: 2022-11-16 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Increasing protein stability by inferring substitution effects from high-throughput experiments. Cell Rep Methods, 2, 2022
3E78	Structure determination of the cancer-associated Mycoplasma hyorhinis protein Mh-p37 Descriptor: CALCIUM ION, CHLORIDE ION, High affinity transport system protein p37, ... Authors: Sippel, K.H, Robbins, A.H, Reutzel, R, Domsic, J, McKenna, R. Deposit date: 2008-08-18 Release date: 2008-10-21 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structure determination of the cancer-associated Mycoplasma hyorhinis protein Mh-p37. Acta Crystallogr.,Sect.D, 64, 2008
7AX0	Crystal structure of the computationally designed Scone-E protein co-crystallized with STA form a Descriptor: Keggin (STA), PHOSPHATE ION, SconeE Authors: Mylemans, B, Vandebroek, L, Parac-Vogt, T.N, Voet, A.R.D. Deposit date: 2020-11-09 Release date: 2021-06-30 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystal structures of Scone: pseudosymmetric folding of a symmetric designer protein. Acta Crystallogr D Struct Biol, 77, 2021
7B4T	Broadly neutralizing DARPin bnD.1 in complex with the HIV-1 envelope variable loop 3 crown mimetic peptide V3-IF (BG505) Descriptor: Broadly neutralizing DARPin bnD.1, HIV-1 envelope variable loop 3 crown mimetic peptide V3-IF (BG505), SULFATE ION Authors: Friedrich, N, Stiegeler, E, Glogl, M, Lemmin, T, Hansen, S, Kadelka, C, Wu, Y, Ernst, P, Maliqi, L, Foulkes, C, Morin, M, Eroglu, M, Liechti, T, Ivan, B, Reinberg, T, Schaefer, J, Karakus, U, Ursprung, S, Mann, A, Rusert, P, Kouyos, R.D, Robinson, J.A, Gunthard, H.F, Pluckthun, A, Trkola, A. Deposit date: 2020-12-02 Release date: 2021-11-24 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Distinct conformations of the HIV-1 V3 loop crown are targetable for broad neutralization. Nat Commun, 12, 2021
7B4U	Broadly neutralizing DARPin bnD.2 in complex with the HIV-1 envelope variable loop 3 crown mimetic peptide V3-IF (BG505) Descriptor: Broadly neutralizing DARPin bnD.2, CALCIUM ION, HIV-1 envelope variable loop 3 crown mimetic peptide V3-IF (BG505) Authors: Friedrich, N, Stiegeler, E, Glogl, M, Lemmin, T, Hansen, S, Kadelka, C, Wu, Y, Ernst, P, Maliqi, L, Foulkes, C, Morin, M, Eroglu, M, Liechti, T, Ivan, B, Reinberg, T, Schaefer, J, Karakus, U, Ursprung, S, Mann, A, Rusert, P, Kouyos, R.D, Robinson, J.A, Gunthard, H.F, Pluckthun, A, Trkola, A. Deposit date: 2020-12-02 Release date: 2021-11-24 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Distinct conformations of the HIV-1 V3 loop crown are targetable for broad neutralization. Nat Commun, 12, 2021
5K5M	Co-Crystal Structure of Dengue Virus Serotype 2 RNA Dependent RNA Polymerase with Compound 27 Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5-[5-(3-hydroxyprop-1-yn-1-yl)thiophen-2-yl]-2,4-dimethoxy-N-[(3-methoxyphenyl)sulfonyl]benzamide, RNA Dependent RNA Polymerase, ... Authors: Arora, R, Benson, T.E. Deposit date: 2016-05-23 Release date: 2016-08-24 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.01 Å) Cite: Potent Allosteric Dengue Virus NS5 Polymerase Inhibitors: Mechanism of Action and Resistance Profiling. Plos Pathog., 12, 2016
5KKG	Crystal structure of E72A mutant of ancestral protein ancMT of ADP-dependent sugar kinases family Descriptor: ADENOSINE MONOPHOSPHATE, GLYCEROL, IODIDE ION, ... Authors: Castro-Fernandez, V, Herrera-Morande, A, Zamora, R, Merino, F, Pereira, H.M, Brandao-Neto, J, Garratt, R, Guixe, V. Deposit date: 2016-06-21 Release date: 2017-07-26 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.608 Å) Cite: Reconstructed ancestral enzymes reveal that negative selection drove the evolution of substrate specificity in ADP-dependent kinases. J. Biol. Chem., 292, 2017
5VF1	X-ray Crystallographic Structure of a Giant Double-Walled Peptide Nanotube Formed by a Macrocyclic Beta-Sheet Containing ABeta16-22 Descriptor: ORN-LYS-LEU-VAL-PHI-PHE-ALA-GLU-ORN-GLU-ALA-PHE-MEA-VAL-LEU-LYS Authors: Chen, K.H, Corro, K.A, Le, S.P, Nowick, J.S. Deposit date: 2017-04-06 Release date: 2017-06-21 Last modified: 2019-11-27 Method: X-RAY DIFFRACTION (2.1 Å) Cite: X-ray Crystallographic Structure of a Giant Double-Walled Peptide Nanotube Formed by a Macrocyclic beta-Sheet Containing A beta 16-22. J. Am. Chem. Soc., 139, 2017
8V3B	Computational Designed Nanocage O43_129_+4 Descriptor: O43_129_+4 component A, O43_129_+4 component B Authors: Carr, K.D, Weidle, C, Borst, A.J. Deposit date: 2023-11-27 Release date: 2024-03-13 Last modified: 2024-04-10 Method: ELECTRON MICROSCOPY (6.4 Å) Cite: Blueprinting extendable nanomaterials with standardized protein blocks. Nature, 627, 2024
6O3N	Cross-alpha Amyloid-like Structure alphaAmA Descriptor: Cross-alpha Amyloid-like Structure alphaAmA Authors: Zhang, S.-Q, Liu, L, DeGrado, W.F. Deposit date: 2019-02-26 Release date: 2019-03-13 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.7 Å) Cite: Designed peptides that assemble into cross-alpha amyloid-like structures Nat. Chem. Biol., 14, 2018
6OWD	Arginine Containing Reengineered Coiled-Coiled Dimer to Examine the Impact of Proximal Cation Identity on Hydrophobically-Driven Assembly Descriptor: CHLORIDE ION, R+7 Authors: Biok, N.A, Bingman, C.A, Gellman, S.H. Deposit date: 2019-05-09 Release date: 2020-03-04 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Retention of Coiled-Coil Dimer Formation in the Absence of Ion Pairing at Positions Flanking the Hydrophobic Core. Biochemistry, 58, 2019
8A1A	Structure of a leucinostatin derivative determined by host lattice display : L1F11V1 construct Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 6-(2-methoxyethoxy)-11,15-dimethyl-8-oxa-2,11,15,19,21,23-hexazatetracyclo[15.6.1.13,7.020,24]pentacosa-1(23),3(25),4,6,17,20(24),21-heptaen-10-one, ... Authors: Mittl, P.R.E. Deposit date: 2022-06-01 Release date: 2022-12-07 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Structure of a hydrophobic leucinostatin derivative determined by host lattice display. Acta Crystallogr D Struct Biol, 78, 2022
8A19	Structure of a leucinostatin derivative determined by host lattice display : L1E4V1 construct Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 6-(2-methoxyethoxy)-11,15-dimethyl-8-oxa-2,11,15,19,21,23-hexazatetracyclo[15.6.1.13,7.020,24]pentacosa-1(23),3(25),4,6,17,20(24),21-heptaen-10-one, ... Authors: Mittl, P.R.E. Deposit date: 2022-06-01 Release date: 2022-12-07 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.358 Å) Cite: Structure of a hydrophobic leucinostatin derivative determined by host lattice display. Acta Crystallogr D Struct Biol, 78, 2022
7ZI1	Crystal structure of dCK C4S-S74E mutant in complex with UDP and the dCKi1 inhibitor Descriptor: Deoxycytidine kinase, N-[3-[[4-(4-azanylpyrimidin-2-yl)-1,3-thiazol-2-yl]amino]-4-methyl-phenyl]-4-[(4-methylpiperazin-1-yl)methyl]benzamide, SODIUM ION, ... Authors: Saez-Ayala, M, Ben-Yaala, K, Betzi, S, Rebuffet, E, Morelli, X. Deposit date: 2022-04-07 Release date: 2023-06-07 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.85 Å) Cite: From a drug repositioning to a structure-based drug design approach to tackle acute lymphoblastic leukemia. Nat Commun, 14, 2023
7ZI9	Crystal structure of dCK C4S-S74E mutant in complex with UDP and the OR0624 inhibitor Descriptor: 2-[2-[[2-methyl-5-[4-(4-methylpiperazin-1-yl)sulfonylphenyl]phenyl]-propyl-amino]-1,3-thiazol-4-yl]pyrimidine-4,6-diamine, Deoxycytidine kinase, SODIUM ION, ... Authors: Saez-Ayala, M, Ben-Yaala, K, Betzi, S, Rebuffet, E, Morelli, X. Deposit date: 2022-04-07 Release date: 2023-06-07 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.8 Å) Cite: From a drug repositioning to a structure-based drug design approach to tackle acute lymphoblastic leukemia. Nat Commun, 14, 2023
7ZI3	Crystal structure of dCK C4S-S74E mutant in complex with UDP and the OR0642 inhibitor Descriptor: 2-[2-[[2-methyl-5-[4-(4-methylpiperazin-1-yl)sulfonyl-2-(trifluoromethyl)phenyl]phenyl]-propyl-amino]-1,3-thiazol-4-yl]pyrimidine-4,6-diamine, Deoxycytidine kinase, SODIUM ION, ... Authors: Ben-Yaala, K, Saez-Ayala, M, Betzi, S, Rebuffet, E, Morelli, X. Deposit date: 2022-04-07 Release date: 2023-06-07 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.9 Å) Cite: From a drug repositioning to a structure-based drug design approach to tackle acute lymphoblastic leukemia. Nat Commun, 14, 2023
7ZI6	Crystal structure of dCK C4S-S74E mutant in complex with UDP and the OR0325 inhibitor Descriptor: 4-(4-azanylpyrimidin-2-yl)-N-[2-methyl-5-[4-[2-(4-methylpiperazin-1-yl)ethyl]phenyl]phenyl]-1,3-thiazol-2-amine, Deoxycytidine kinase, SODIUM ION, ... Authors: Saez-Ayala, M, Ben-Yaala, K, Betzi, S, Rebuffet, E, Morelli, X. Deposit date: 2022-04-07 Release date: 2023-06-07 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.1 Å) Cite: From a drug repositioning to a structure-based drug design approach to tackle acute lymphoblastic leukemia. Nat Commun, 14, 2023

<115116117118119120121122123124125126127128129130>