5VKL
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![BU of 5vkl by Molmil](/molmil-images/mine/5vkl) | SPT6 tSH2-RPB1 1476-1500 pS1493 | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, Transcription elongation factor SPT6 | Authors: | Sdano, M.A, Whitby, F.G, Hill, C.P. | Deposit date: | 2017-04-21 | Release date: | 2017-10-25 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.198 Å) | Cite: | A novel SH2 recognition mechanism recruits Spt6 to the doubly phosphorylated RNA polymerase II linker at sites of transcription. Elife, 6, 2017
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3PJP
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![BU of 3pjp by Molmil](/molmil-images/mine/3pjp) | A Tandem SH2 Domain in Transcription Elongation Factor Spt6 Binds the Phosphorylated RNA Polymerase II C-terminal Repeat Domain(CTD) | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETATE ION, Transcription elongation factor SPT6 | Authors: | Sun, M, Lariviere, L, Dengl, S, Mayer, A, Cramer, P. | Deposit date: | 2010-11-10 | Release date: | 2010-11-24 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | A tandem SH2 domain in transcription elongation factor Spt6 binds the phosphorylated RNA polymerase II C-terminal repeat domain (CTD). J.Biol.Chem., 285, 2010
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7XSE
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![BU of 7xse by Molmil](/molmil-images/mine/7xse) | RNA polymerase II elongation complex transcribing a nucleosome (EC42) | Descriptor: | Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ... | Authors: | Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S. | Deposit date: | 2022-05-13 | Release date: | 2022-09-07 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT. Science, 377, 2022
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7XTD
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![BU of 7xtd by Molmil](/molmil-images/mine/7xtd) | RNA polymerase II elongation complex transcribing a nucleosome (EC58oct) | Descriptor: | Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ... | Authors: | Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S. | Deposit date: | 2022-05-16 | Release date: | 2022-09-07 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT. Science, 377, 2022
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7XSX
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![BU of 7xsx by Molmil](/molmil-images/mine/7xsx) | RNA polymerase II elongation complex transcribing a nucleosome (EC49) | Descriptor: | Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ... | Authors: | Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S. | Deposit date: | 2022-05-15 | Release date: | 2022-09-07 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT. Science, 377, 2022
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7XSZ
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![BU of 7xsz by Molmil](/molmil-images/mine/7xsz) | RNA polymerase II elongation complex transcribing a nucleosome (EC115) | Descriptor: | Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ... | Authors: | Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S. | Deposit date: | 2022-05-15 | Release date: | 2022-09-07 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT. Science, 377, 2022
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7XT7
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![BU of 7xt7 by Molmil](/molmil-images/mine/7xt7) | RNA polymerase II elongation complex transcribing a nucleosome (EC49B) | Descriptor: | Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ... | Authors: | Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S. | Deposit date: | 2022-05-16 | Release date: | 2022-10-12 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT. Science, 377, 2022
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7XTI
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![BU of 7xti by Molmil](/molmil-images/mine/7xti) | RNA polymerase II elongation complex transcribing a nucleosome (EC58hex) | Descriptor: | Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ... | Authors: | Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S. | Deposit date: | 2022-05-17 | Release date: | 2022-10-12 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT. Science, 377, 2022
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7XN7
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![BU of 7xn7 by Molmil](/molmil-images/mine/7xn7) | RNA polymerase II elongation complex containing Spt4/5, Elf1, Spt6, Spn1 and Paf1C | Descriptor: | Chromatin elongation factor SPT5, Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, ... | Authors: | Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S. | Deposit date: | 2022-04-28 | Release date: | 2022-09-07 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT. Science, 377, 2022
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5G5L
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![BU of 5g5l by Molmil](/molmil-images/mine/5g5l) | RNA polymerase I-Rrn3 complex at 4.8 A resolution | Descriptor: | DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA12, DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135, DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA14, ... | Authors: | Engel, C, Plitzko, J, Cramer, P. | Deposit date: | 2016-05-26 | Release date: | 2016-07-27 | Last modified: | 2018-10-24 | Method: | ELECTRON MICROSCOPY (4.8 Å) | Cite: | RNA Polymerase I-Rrn3 Complex at 4.8 A Resolution Nat.Commun., 7, 2016
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6QX8
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![BU of 6qx8 by Molmil](/molmil-images/mine/6qx8) | Influenza A virus (A/NT/60/1968) polymerase dimer of heterotrimer in complex with 5' cRNA promoter | Descriptor: | Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-R(P*AP*GP*CP*AP*AP*AP*AP*GP*CP*AP*GP*A)-3'), ... | Authors: | Carrique, L, Keown, J.R, Fan, H, Fodor, E, Grimes, J.M. | Deposit date: | 2019-03-07 | Release date: | 2019-09-04 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.07 Å) | Cite: | Structures of influenza A virus RNA polymerase offer insight into viral genome replication. Nature, 573, 2019
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6RR7
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![BU of 6rr7 by Molmil](/molmil-images/mine/6rr7) | Influenza A virus (A/NT/60/1968) polymerase Heterotrimer bound to 3'5' vRNA promoter and capped RNA primer | Descriptor: | Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-D(*(M7G))-R(P*AP*AP*UP*CP*U)-3'), ... | Authors: | Carrique, L, Keown, J.R, Fan, H, Fodor, E, Grimes, J.M. | Deposit date: | 2019-05-17 | Release date: | 2019-09-04 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.01 Å) | Cite: | Structures of influenza A virus RNA polymerase offer insight into viral genome replication. Nature, 573, 2019
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6QNW
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![BU of 6qnw by Molmil](/molmil-images/mine/6qnw) | |
6QPF
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![BU of 6qpf by Molmil](/molmil-images/mine/6qpf) | Influenza A virus Polymerase Heterotrimer A/duck/Fujian/01/2002(H5N1) | Descriptor: | Polymerase acidic protein, Polymerase basic protein 2, RNA-directed RNA polymerase catalytic subunit | Authors: | Fan, H.T, Keown, J.R, Fodor, E, Grimes, J.M. | Deposit date: | 2019-02-13 | Release date: | 2019-09-04 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.634 Å) | Cite: | Structures of influenza A virus RNA polymerase offer insight into viral genome replication. Nature, 573, 2019
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7ZXE
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![BU of 7zxe by Molmil](/molmil-images/mine/7zxe) | Structure of SNAPc containing Pol II pre-initiation complex bound to U1 snRNA promoter (OC) | Descriptor: | Non-template strand, TATA-box-binding protein, Template strand, ... | Authors: | Rengachari, S, Schilbach, S, Kaliyappan, T, Gouge, J, Zumer, K, Schwarz, J, Urlaub, H, Dienemann, C, Vannini, A, Cramer, P. | Deposit date: | 2022-05-20 | Release date: | 2022-11-30 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II. Nat.Struct.Mol.Biol., 29, 2022
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7ZWC
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![BU of 7zwc by Molmil](/molmil-images/mine/7zwc) | Structure of SNAPc:TBP-TFIIA-TFIIB sub-complex bound to U5 snRNA promoter | Descriptor: | Non-template strand, TATA-box-binding protein, Template strand, ... | Authors: | Rengachari, S, Schilbach, S, Kaliyappan, T, Gouge, J, Zumer, K, Schwarz, J, Urlaub, H, Dienemann, C, Vannini, A, Cramer, P. | Deposit date: | 2022-05-19 | Release date: | 2022-11-30 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II. Nat.Struct.Mol.Biol., 29, 2022
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7NHX
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![BU of 7nhx by Molmil](/molmil-images/mine/7nhx) | 1918 H1N1 Viral influenza polymerase heterotrimer - full transcriptase (Class1) | Descriptor: | Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*CP*C)-3'), ... | Authors: | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | Deposit date: | 2021-02-11 | Release date: | 2021-12-01 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.23 Å) | Cite: | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
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7NI0
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![BU of 7ni0 by Molmil](/molmil-images/mine/7ni0) | 1918 H1N1 Viral influenza polymerase heterotrimer - Replicase (class 3) | Descriptor: | Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*CP*C)-3'), ... | Authors: | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | Deposit date: | 2021-02-11 | Release date: | 2021-12-01 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.32 Å) | Cite: | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
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7NHA
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![BU of 7nha by Molmil](/molmil-images/mine/7nha) | 1918 H1N1 Viral influenza polymerase heterotrimer - Endonuclease and priming loop ordered (Class2a) | Descriptor: | Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*CP*C)-3'), ... | Authors: | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | Deposit date: | 2021-02-10 | Release date: | 2021-12-01 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.91 Å) | Cite: | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
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7NHC
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![BU of 7nhc by Molmil](/molmil-images/mine/7nhc) | 1918 H1N1 Viral influenza polymerase heterotrimer - Endonuclease ordered (Class2b) | Descriptor: | Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*CP*C)-3'), ... | Authors: | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | Deposit date: | 2021-02-10 | Release date: | 2021-12-01 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.87 Å) | Cite: | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
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4PN1
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![BU of 4pn1 by Molmil](/molmil-images/mine/4pn1) | |
2WAQ
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![BU of 2waq by Molmil](/molmil-images/mine/2waq) | The complete structure of the archaeal 13-subunit DNA-directed RNA Polymerase | Descriptor: | DNA-DIRECTED RNA POLYMERASE RPO10 SUBUNIT, DNA-DIRECTED RNA POLYMERASE RPO11 SUBUNIT, DNA-DIRECTED RNA POLYMERASE RPO12 SUBUNIT, ... | Authors: | Korkhin, Y, Unligil, U.M, Littlefield, O, Nelson, P.J, Stuart, D.I, Sigler, P.B, Bell, S.D, Abrescia, N.G.A. | Deposit date: | 2009-02-11 | Release date: | 2009-05-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.35 Å) | Cite: | Evolution of complex RNA polymerases: the complete archaeal RNA polymerase structure. Plos Biol., 7, 2009
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5M64
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![BU of 5m64 by Molmil](/molmil-images/mine/5m64) | RNA Polymerase I elongation complex with A49 tandem winged helix domain | Descriptor: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | Authors: | Tafur, L, Sadian, Y, Hoffmann, N.A, Jakobi, A.J, Wetzel, R, Hagen, W.J.H, Sachse, C, Muller, C.W. | Deposit date: | 2016-10-24 | Release date: | 2016-12-21 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Molecular Structures of Transcribing RNA Polymerase I. Mol. Cell, 64, 2016
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5M5W
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![BU of 5m5w by Molmil](/molmil-images/mine/5m5w) | RNA Polymerase I open complex | Descriptor: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | Authors: | Tafur, L, Sadian, Y, Hoffmann, N.A, Jakobi, A.J, Wetzel, R, Hagen, W.J.H, Sachse, C, Muller, C.W. | Deposit date: | 2016-10-23 | Release date: | 2016-12-07 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Molecular Structures of Transcribing RNA Polymerase I. Mol. Cell, 64, 2016
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5M5X
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![BU of 5m5x by Molmil](/molmil-images/mine/5m5x) | RNA Polymerase I elongation complex 1 | Descriptor: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | Authors: | Tafur, L, Sadian, Y, Hoffmann, N.A, Jakobi, A.J, Wetzel, R, Hagen, W.J.H, Sachse, C, Muller, C.W. | Deposit date: | 2016-10-23 | Release date: | 2016-12-21 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Molecular Structures of Transcribing RNA Polymerase I. Mol. Cell, 64, 2016
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