PDB: 313 resultsInfo pagesStatus searchChemie searchBIRD

---

7W5W	Cryo-EM structure of SoxS-dependent transcription activation complex with micF promoter DNA Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Lin, W, Feng, Y. Deposit date: 2021-11-30 Release date: 2022-10-26 Last modified: 2022-11-16 Method: ELECTRON MICROSCOPY (4.55 Å) Cite: Structural basis of three different transcription activation strategies adopted by a single regulator SoxS. Nucleic Acids Res., 50, 2022
7W5Y	Cryo-EM structure of SoxS-dependent transcription activation complex with fpr promoter DNA Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Lin, W, Feng, Y. Deposit date: 2021-11-30 Release date: 2022-10-26 Last modified: 2022-11-16 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: Structural basis of three different transcription activation strategies adopted by a single regulator SoxS. Nucleic Acids Res., 50, 2022
7W5X	Cryo-EM structure of SoxS-dependent transcription activation complex with zwf promoter DNA Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Lin, W, Feng, Y, Shi, J. Deposit date: 2021-11-30 Release date: 2022-10-26 Last modified: 2022-11-16 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structural basis of three different transcription activation strategies adopted by a single regulator SoxS. Nucleic Acids Res., 50, 2022
7U22	Mycobacterium tuberculosis RNA polymerase sigma A holoenzyme open promoter complex containing UMN-7 Descriptor: (9S,14S,15R,16S,17R,18R,19R,20S,21S,25R)-5,6,18,20-tetrahydroxy-14-methoxy-7,9,15,17,19,21,25-heptamethyl-1'-(2-methylpropyl)-10,26-dioxo-1,3,9,10-tetrahydrospiro[9,4-(epoxypentadecanoimino)furo[2',3':7,8]naphtho[1,2-d]imidazole-2,4'-piperidin]-16-yl benzoate, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Molodtsov, V, Ebright, R.H. Deposit date: 2022-02-22 Release date: 2022-10-19 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (3.87 Å) Cite: Redesign of Rifamycin Antibiotics to Overcome ADP-Ribosylation-Mediated Resistance. Angew.Chem.Int.Ed.Engl., 61, 2022
7X76	Cryo-EM structure of Streptomyces coelicolor RNAP-promoter open complex with two Zur dimers Descriptor: DNA (84-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Yang, X, Zheng, J. Deposit date: 2022-03-09 Release date: 2022-08-03 Last modified: 2022-08-24 Method: ELECTRON MICROSCOPY (3.67 Å) Cite: Structural basis of Streptomyces transcription activation by zinc uptake regulator. Nucleic Acids Res., 50, 2022
7X74	Cryo-EM structure of Streptomyces coelicolor transcription initial complex with two Zur dimers. Descriptor: DNA (84-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Yang, X, Zheng, J. Deposit date: 2022-03-09 Release date: 2022-08-03 Last modified: 2022-12-14 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Structural basis of Streptomyces transcription activation by zinc uptake regulator. Nucleic Acids Res., 50, 2022
7X75	Cryo-EM structure of Streptomyces coelicolor RNAP-promoter open complex with three Zur dimers Descriptor: DNA (84-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Yang, X, Zheng, J. Deposit date: 2022-03-09 Release date: 2022-08-03 Last modified: 2022-08-24 Method: ELECTRON MICROSCOPY (3.45 Å) Cite: Structural basis of Streptomyces transcription activation by zinc uptake regulator. Nucleic Acids Res., 50, 2022
7UBM	Transcription antitermination complex: "pre-engaged" Qlambda-loading complex Descriptor: Antitermination protein Q, DNA (52-MER), DNA (53-MER), ... Authors: Yin, Z, Ebright, R.H. Deposit date: 2022-03-15 Release date: 2022-09-28 Last modified: 2024-06-12 Method: ELECTRON MICROSCOPY (3.13 Å) Cite: In transcription antitermination by Q lambda , NusA induces refolding of Q lambda to form a nozzle that extends the RNA polymerase RNA-exit channel. Proc.Natl.Acad.Sci.USA, 119, 2022
7UBN	Transcription antitermination complex: NusA-containing "engaged" Qlambda-loading complex Descriptor: Antitermination protein, DNA (52-MER), DNA (53-MER), ... Authors: Yin, Z, Ebright, R.H. Deposit date: 2022-03-15 Release date: 2022-09-28 Last modified: 2024-06-12 Method: ELECTRON MICROSCOPY (3.36 Å) Cite: In transcription antitermination by Q lambda , NusA induces refolding of Q lambda to form a nozzle that extends the RNA polymerase RNA-exit channel. Proc.Natl.Acad.Sci.USA, 119, 2022
7ZF2	Protomeric substructure from an octameric assembly of M. tuberculosis RNA polymerase in complex with sigma-b initiation factor Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Trapani, S, Bron, P, Lai Kee Him, J, Brodolin, K, Morichaud, Z, Vishwakarma, R. Deposit date: 2022-03-31 Release date: 2023-02-08 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (3.86 Å) Cite: Structural basis of the mycobacterial stress-response RNA polymerase auto-inhibition via oligomerization. Nat Commun, 14, 2023
7XL3	Cryo-EM structure of Pseudomonas aeruginosa RNAP sigmaS holoenzyme complexes with transcription factor SutA (open lobe) Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: He, D.W, You, L.L, Zhang, Y. Deposit date: 2022-04-21 Release date: 2022-07-27 Last modified: 2022-08-03 Method: ELECTRON MICROSCOPY (3.13 Å) Cite: Pseudomonas aeruginosa SutA wedges RNAP lobe domain open to facilitate promoter DNA unwinding. Nat Commun, 13, 2022
7XL4	Cryo-EM structure of Pseudomonas aeruginosa RNAP sigmaS holoenzyme complexes with transcription factor SutA (closed lobe) Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: He, D.W, You, L.L, Zhang, Y. Deposit date: 2022-04-21 Release date: 2022-07-27 Last modified: 2023-02-08 Method: ELECTRON MICROSCOPY (3.86 Å) Cite: Pseudomonas aeruginosa SutA wedges RNAP lobe domain open to facilitate promoter DNA unwinding. Nat Commun, 13, 2022
7XUI	Cryo-EM structure of sigma70 bound HK022 putRNA-associated E.coli RNA polymerase elongation complex Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Hwang, S, Kang, J.Y. Deposit date: 2022-05-18 Release date: 2022-08-10 Last modified: 2022-08-31 Method: ELECTRON MICROSCOPY (3.61 Å) Cite: Structural basis of transcriptional regulation by a nascent RNA element, HK022 putRNA. Nat Commun, 13, 2022
8CWT	Complex structure of WhiB3 and the SigmaAr4-RNAP Beta flap tip chimera in space group P43212 Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, IRON/SULFUR CLUSTER, NICKEL (II) ION, ... Authors: Wan, T, Zhang, L. Deposit date: 2022-05-19 Release date: 2023-05-17 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.35 Å) Cite: Structural basis of DNA binding by the WhiB-like transcription factor WhiB3 in Mycobacterium tuberculosis. J.Biol.Chem., 299, 2023
8CWR	Complex structure of WhiB3 and the SigmaAr4-RNAP Beta flap tip chimera in space group R3 Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, IRON/SULFUR CLUSTER, NICKEL (II) ION, ... Authors: Wan, T, Zhang, L. Deposit date: 2022-05-19 Release date: 2023-05-17 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Structural basis of DNA binding by the WhiB-like transcription factor WhiB3 in Mycobacterium tuberculosis. J.Biol.Chem., 299, 2023
8CYF	WhiB3 bound to SigmaAr4-RNAP Beta flap tip chimera and DNA Descriptor: CACODYLATE ION, DNA (5'-D(*CP*AP*CP*CP*AP*CP*AP*AP*CP*CP*GP*AP*TP*TP*TP*T)-3'), DNA (5'-D(*GP*AP*AP*AP*AP*TP*CP*GP*GP*TP*TP*GP*TP*GP*GP*T)-3'), ... Authors: Wan, T, Zhang, L.M. Deposit date: 2022-05-23 Release date: 2023-05-17 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.44 Å) Cite: Structural basis of DNA binding by the WhiB-like transcription factor WhiB3 in Mycobacterium tuberculosis. J.Biol.Chem., 299, 2023
7XYA	The cryo-EM structure of an AlpA-loading complex Descriptor: AlpA, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Wen, A, Feng, Y. Deposit date: 2022-06-01 Release date: 2022-07-20 Last modified: 2022-08-24 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Structural basis of AlpA-dependent transcription antitermination. Nucleic Acids Res., 50, 2022
8D5V	WhiB6 bound to the SigmaAr4-RNAP Beta flap tip chimera Descriptor: IRON/SULFUR CLUSTER, Probable transcriptional regulator WhiB6, RNA polymerase sigma factor SigA,DNA-directed RNA polymerase subunit beta Authors: Wan, T, Zhang, L.M. Deposit date: 2022-06-06 Release date: 2023-06-14 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal structure of WhiB6 and SigA4-betaTip complex To Be Published
7YE2	The cryo-EM structure of C. crescentus GcrA-TACdown Descriptor: Cell cycle regulatory protein GcrA, DNA (90-MER)-non template, DNA (90-MER)-template, ... Authors: Wu, X.X, Zhang, Y. Deposit date: 2022-07-05 Release date: 2023-01-18 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Cryo-EM structures of Caulobacter crescentus transcription activation complex with an essential cell cycle regulator GcrA Nucleic Acids Res., 2023
7YE1	The cryo-EM structure of C. crescentus GcrA-TACup Descriptor: Cell cycle regulatory protein GcrA, DNA (57-MER)-non template, DNA (57-MER)-template, ... Authors: Wu, X.X, Zhang, Y. Deposit date: 2022-07-05 Release date: 2023-01-18 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Cryo-EM structures of Caulobacter crescentus transcription activation complex with an essential cell cycle regulator GcrA Nucleic Acids Res., 2023
8AD1	RNA polymerase at U-rich pause bound to RNA putL triple mutant - pause prone, closed clamp state Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Dey, S, Weixlbaumer, A. Deposit date: 2022-07-07 Release date: 2022-10-19 Last modified: 2022-11-02 Method: ELECTRON MICROSCOPY (4.1 Å) Cite: Structural insights into RNA-mediated transcription regulation in bacteria. Mol.Cell, 82, 2022
8DY9	Streptomyces venezuelae RNAP unconstrained open promoter complex with WhiA and WhiB transcription factors Descriptor: DNA (38-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Lilic, M, Campbell, E.A. Deposit date: 2022-08-03 Release date: 2023-03-01 Last modified: 2024-06-12 Method: ELECTRON MICROSCOPY (3.12 Å) Cite: Structural basis of dual activation of cell division by the actinobacterial transcription factors WhiA and WhiB. Proc.Natl.Acad.Sci.USA, 120, 2023
8DY7	Streptomyces venezuelae RNAP transcription open promoter complex with WhiA and WhiB transcription factors Descriptor: DNA (71-MER), DNA (78-MER), DNA-directed RNA polymerase subunit alpha, ... Authors: Lilic, M, Campbell, E.A. Deposit date: 2022-08-03 Release date: 2023-03-01 Last modified: 2024-06-12 Method: ELECTRON MICROSCOPY (3.18 Å) Cite: Structural basis of dual activation of cell division by the actinobacterial transcription factors WhiA and WhiB. Proc.Natl.Acad.Sci.USA, 120, 2023
8GZH	Cryo-EM structure of Synechocystis sp. PCC 6803 CTP-bound RPitc Descriptor: CYTIDINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: You, L.L, Shen, L.Q, Zhang, Y. Deposit date: 2022-09-27 Release date: 2023-04-19 Method: ELECTRON MICROSCOPY (2.96 Å) Cite: Cryo-EM structure of Synechocystis sp. PCC 6803 CTP-bound RPitc Proc.Natl.Acad.Sci.USA, 2023
8GZG	Cryo-EM structure of Synechocystis sp. PCC 6803 RPitc Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Shen, L.Q, You, L.L, Zhang, Y. Deposit date: 2022-09-27 Release date: 2023-04-19 Method: ELECTRON MICROSCOPY (3.13 Å) Cite: Cryo-EM structure of Synechocystis sp. PCC 6803 CTP-bound RPitc Proc.Natl.Acad.Sci.USA, 2023

<5678910111213>