2PG1
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2NYJ
| Crystal structure of the ankyrin repeat domain of TRPV1 | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Transient receptor potential cation channel subfamily V member 1 | Authors: | Jin, X, Gaudet, R. | Deposit date: | 2006-11-20 | Release date: | 2007-07-03 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | The Ankyrin Repeats of TRPV1 Bind Multiple Ligands and Modulate Channel Sensitivity. Neuron, 54, 2007
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3GIS
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3LCI
| The D-sialic acid aldolase mutant V251W | Descriptor: | N-acetylneuraminate lyase, SULFATE ION | Authors: | Chou, C.-Y, Wang, A.H.-J, Ko, T.-P. | Deposit date: | 2010-01-11 | Release date: | 2011-01-19 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.12 Å) | Cite: | Modulation of substrate specificities of D-sialic acid aldolase through single mutations of Val251 To be Published
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3H0E
| 3,4-Dihydropyrimido(1,2-a)indol-10(2H)-ones as Potent Non-Peptidic Inhibitors of Caspase-3 | Descriptor: | (10S)-3,3-dimethyl-8-{[(2S)-2-(phenoxymethyl)pyrrolidin-1-yl]sulfonyl}-2,3,4,10-tetrahydropyrimido[1,2-a]indol-10-ol, Caspase-3 | Authors: | Xu, W. | Deposit date: | 2009-04-09 | Release date: | 2009-11-17 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.997 Å) | Cite: | 3,4-Dihydropyrimido(1,2-a)indol-10(2H)-ones as potent non-peptidic inhibitors of caspase-3 Bioorg.Med.Chem., 17, 2009
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3LQ5
| Structure of CDK9/CyclinT in complex with S-CR8 | Descriptor: | (2S)-2-({9-(1-methylethyl)-6-[(4-pyridin-2-ylbenzyl)amino]-9H-purin-2-yl}amino)butan-1-ol, Cell division protein kinase 9, Cyclin-T1 | Authors: | Hole, A.J, Endicott, J.A, Baumli, S. | Deposit date: | 2010-02-08 | Release date: | 2011-01-19 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | CDK Inhibitors Roscovitine and CR8 Trigger Mcl-1 Down-Regulation and Apoptotic Cell Death in Neuroblastoma Cells Genes Cancer, 1, 2010
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3EOV
| Crystal structure of cyclophilin from Leishmania donovani ligated with cyclosporin A | Descriptor: | CYCLOSPORIN A, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE | Authors: | Venugopal, V, Dasgupta, D, Datta, A.K, Banerjee, R. | Deposit date: | 2008-09-29 | Release date: | 2008-11-11 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of Cyclophilin from Leishmania Donovani Bound to Cyclosporin at 2.6 A Resolution: Correlation between Structure and Thermodynamic Data. Acta Crystallogr.,Sect.D, 65, 2009
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2QOR
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1TDP
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1U9F
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1TTL
| Omega-conotoxin GVIA, a N-type calcium channel blocker | Descriptor: | Omega-conotoxin GVIA | Authors: | Mould, J, Yasuda, T, Schroeder, C.I, Beedle, A.M, Doering, C.J, Zamponi, G.W, Adams, D.J, Lewis, R.J. | Deposit date: | 2004-06-23 | Release date: | 2004-07-13 | Last modified: | 2011-07-13 | Method: | SOLUTION NMR | Cite: | The alpha2delta auxiliary subunit reduces affinity of omega-conotoxins for recombinant N-type (Cav2.2) calcium channels J.Biol.Chem., 279, 2004
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1U9H
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1U9G
| Heterocyclic Peptide Backbone Modification in GCN4-pLI Based Coiled Coils: Replacement of K(8)L(9) | Descriptor: | General control protein GCN4, SULFATE ION | Authors: | Horne, W.S, Yadav, M.K, Stout, C.D, Ghadiri, M.R. | Deposit date: | 2004-08-09 | Release date: | 2004-11-30 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Heterocyclic peptide backbone modifications in an alpha-helical coiled coil. J.Am.Chem.Soc., 126, 2004
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1TR6
| NMR solution structure of omega-conotoxin [K10]GVIA, a cyclic cysteine knot peptide | Descriptor: | Omega-conotoxin GVIA | Authors: | Mould, J, Yasuda, T, Schroeder, C.I, Beedle, A.M, Doering, C.J, Zamponi, G.W, Adams, D.J, Lewis, R.J. | Deposit date: | 2004-06-21 | Release date: | 2004-07-13 | Last modified: | 2011-10-05 | Method: | SOLUTION NMR | Cite: | The alpha2delta auxiliary subunit reduces affinity of omega-conotoxins for recombinant N-type (Cav2.2) calcium channels J.Biol.Chem., 279, 2004
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1USU
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1US7
| Complex of Hsp90 and P50 | Descriptor: | HEAT SHOCK PROTEIN HSP82, HSP90 CO-CHAPERONE CDC37 | Authors: | Roe, S.M, Ali, M.M.U, Pearl, L.H. | Deposit date: | 2003-11-20 | Release date: | 2004-01-15 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The Mechanism of Hsp90 Regulation by the Protein Kinase-Specific Cochaperone p50(Cdc37) Cell(Cambridge,Mass.), 116, 2004
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1USV
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1X3B
| Solution structure of the FAS1 domain of human transforming growth factor-beta induced protein IG-H3 | Descriptor: | Transforming growth factor-beta induced protein IG-H3 | Authors: | Yoneyama, M, Tomizawa, T, Tochio, N, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-05-02 | Release date: | 2005-11-02 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the FAS1 domain of human transforming growth factor-beta induced protein IG-H3 To be Published
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2J32
| The Role of Loop Bundle Hydrogen Bonds in the Maturation and Activity of(Pro)caspase-3 | Descriptor: | ACE-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE INHIBITOR, CASPASE-3 | Authors: | Feeney, B, Pop, C, Swartz, P, Mattos, C, Clark, A.C. | Deposit date: | 2006-08-17 | Release date: | 2006-11-08 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Role of Loop Bundle Hydrogen Bonds in the Maturation and Activity of (Pro)Caspase-3. Biochemistry, 45, 2006
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2KRA
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2J31
| The Role of Loop Bundle Hydrogen Bonds in the Maturation and Activity of(Pro)caspase-3 | Descriptor: | ACE-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE INHIBITOR, CASPASE-3 | Authors: | Feeney, B, Pop, C, Swartz, P, Mattos, C, Clark, A.C. | Deposit date: | 2006-08-17 | Release date: | 2006-11-08 | Last modified: | 2019-05-08 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Role of Loop Bundle Hydrogen Bonds in the Maturation and Activity of (Pro)Caspase-3. Biochemistry, 45, 2006
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2IMG
| Crystal structure of dual specificity protein phosphatase 23 from Homo sapiens in complex with ligand malate ion | Descriptor: | D-MALATE, Dual specificity protein phosphatase 23 | Authors: | Agarwal, R, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2006-10-04 | Release date: | 2006-10-17 | Last modified: | 2021-02-03 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Structure of human dual specificity protein phosphatase 23, VHZ, enzyme-substrate/product complex. J.Biol.Chem., 283, 2008
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2J33
| The Role of Loop Bundle Hydrogen Bonds in the Maturation and Activity of (Pro)caspase-3 | Descriptor: | ACE-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE INHIBITOR, CASPASE-3 | Authors: | Feeney, B, Pop, C, Swartz, P, Mattos, C, Clark, A.C. | Deposit date: | 2006-08-17 | Release date: | 2006-11-08 | Last modified: | 2019-05-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Role of Loop Bundle Hydrogen Bonds in the Maturation and Activity of (Pro)Caspase-3. Biochemistry, 45, 2006
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2J4T
| Biological and Structural Features of Murine Angiogenin-4, an Angiogenic Protein | Descriptor: | ANGIOGENIN-4 | Authors: | Crabtree, B, Holloway, D.E, Baker, M.D, Acharya, K.R, Subramanian, V. | Deposit date: | 2006-09-05 | Release date: | 2007-02-20 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Biological and Structural Features of Murine Angiogenin-4, an Angiogenic Protein Biochemistry, 46, 2007
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2J30
| The Role of Loop Bundle Hydrogen Bonds in the Maturation and Activity of (Pro)caspase-3 | Descriptor: | ACE-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE INHIBITOR, CASPASE-3 | Authors: | Feeney, B, Pop, C, Swartz, P, Mattos, C, Clark, A.C. | Deposit date: | 2006-08-17 | Release date: | 2006-11-08 | Last modified: | 2019-05-08 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Role of Loop Bundle Hydrogen Bonds in the Maturation and Activity of (Pro)Caspase-3. Biochemistry, 45, 2006
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