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7ZEB
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BU of 7zeb by Molmil
Complex I from Ovis aries at pH9, Closed state
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ADENOSINE MONOPHOSPHATE, ...
Authors:Sazanov, L, Petrova, O.
Deposit date:2022-03-30
Release date:2022-09-21
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:A universal coupling mechanism of respiratory complex I.
Nature, 609, 2022
7Z84
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BU of 7z84 by Molmil
Complex I from E. coli, DDM/LMNG-purified, under Turnover at pH 8, Open-ready state
Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, CALCIUM ION, ...
Authors:Kravchuk, V, Kampjut, D, Sazanov, L.
Deposit date:2022-03-16
Release date:2022-09-21
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (2.87 Å)
Cite:A universal coupling mechanism of respiratory complex I.
Nature, 609, 2022
7Z7S
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BU of 7z7s by Molmil
Complex I from E. coli, LMNG-purified, under Turnover at pH 6, Closed state
Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione, ...
Authors:Kravchuk, V, Kampjut, D, Sazanov, L.
Deposit date:2022-03-16
Release date:2022-09-21
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:A universal coupling mechanism of respiratory complex I.
Nature, 609, 2022
7Z80
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BU of 7z80 by Molmil
Complex I from E. coli, DDM/LMNG-purified, under Turnover at pH 8, Closed state
Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione, ...
Authors:Kravchuk, V, Kampjut, D, Sazanov, L.
Deposit date:2022-03-16
Release date:2022-09-21
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (2.93 Å)
Cite:A universal coupling mechanism of respiratory complex I.
Nature, 609, 2022
7ZD6
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BU of 7zd6 by Molmil
Complex I from Ovis aries, at pH7.4, Open state
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ...
Authors:Sazanov, L, Petrova, O.
Deposit date:2022-03-29
Release date:2022-09-21
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (3.16 Å)
Cite:A universal coupling mechanism of respiratory complex I.
Nature, 609, 2022
7ZDJ
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BU of 7zdj by Molmil
Complex I from Ovis aries at pH5.5, Open state
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Acyl carrier protein, Complex I subunit B13, ...
Authors:Petrova, O, Sazanov, L.
Deposit date:2022-03-29
Release date:2022-09-21
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (3.25 Å)
Cite:A universal coupling mechanism of respiratory complex I.
Nature, 609, 2022
7Z7V
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BU of 7z7v by Molmil
Complex I from E. coli, LMNG-purified, under Turnover at pH 6, Open-ready state
Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, CALCIUM ION, ...
Authors:Kravchuk, V, Kampjut, D, Sazanov, L.
Deposit date:2022-03-16
Release date:2022-09-21
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (2.29 Å)
Cite:A universal coupling mechanism of respiratory complex I.
Nature, 609, 2022
7ZDH
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BU of 7zdh by Molmil
Complex I from Ovis aries at pH7.4, Closed state
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ...
Authors:Sazanov, L, Petrova, O.
Deposit date:2022-03-29
Release date:2022-09-21
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (3.46 Å)
Cite:A universal coupling mechanism of respiratory complex I.
Nature, 609, 2022
7Z7R
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BU of 7z7r by Molmil
Complex I from E. coli, LMNG-purified, Apo, Open-ready state
Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, CALCIUM ION, EICOSANE, ...
Authors:Kravchuk, V, Kampjut, D, Sazanov, L.
Deposit date:2022-03-16
Release date:2022-09-21
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (3.36 Å)
Cite:A universal coupling mechanism of respiratory complex I.
Nature, 609, 2022
7ZCI
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BU of 7zci by Molmil
Complex I from E. coli, LMNG-purified, under Turnover at pH 6, Resting state
Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, CALCIUM ION, ...
Authors:Kravchuk, V, Kampjut, D, Sazanov, L.
Deposit date:2022-03-28
Release date:2022-09-21
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (2.69 Å)
Cite:A universal coupling mechanism of respiratory complex I.
Nature, 609, 2022
7Z0T
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BU of 7z0t by Molmil
Structure of the Escherichia coli formate hydrogenlyase complex (aerobic preparation, composite structure)
Descriptor: 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE, CARBONMONOXIDE-(DICYANO) IRON, FE (III) ION, ...
Authors:Steinhilper, R, Murphy, B.J.
Deposit date:2022-02-23
Release date:2022-09-28
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure of the membrane-bound formate hydrogenlyase complex from Escherichia coli.
Nat Commun, 13, 2022
7ZM7
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BU of 7zm7 by Molmil
CryoEM structure of mitochondrial complex I from Chaetomium thermophilum (inhibited by DDM)
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ...
Authors:Laube, E, Kuehlbrandt, W.
Deposit date:2022-04-19
Release date:2022-11-30
Last modified:2022-12-07
Method:ELECTRON MICROSCOPY (2.77 Å)
Cite:Conformational changes in mitochondrial complex I of the thermophilic eukaryote Chaetomium thermophilum.
Sci Adv, 8, 2022
7ZMG
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BU of 7zmg by Molmil
CryoEM structure of mitochondrial complex I from Chaetomium thermophilum (state 1)
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ...
Authors:Laube, E, Kuehlbrandt, W.
Deposit date:2022-04-19
Release date:2022-11-30
Last modified:2022-12-07
Method:ELECTRON MICROSCOPY (2.44 Å)
Cite:Conformational changes in mitochondrial complex I of the thermophilic eukaryote Chaetomium thermophilum.
Sci Adv, 8, 2022
7QSL
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BU of 7qsl by Molmil
Bovine complex I in lipid nanodisc, Active-apo
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ...
Authors:Chung, I, Bridges, H.R, Hirst, J.
Deposit date:2022-01-13
Release date:2022-05-25
Last modified:2022-09-28
Method:ELECTRON MICROSCOPY (2.76 Å)
Cite:Cryo-EM structures define ubiquinone-10 binding to mitochondrial complex I and conformational transitions accompanying Q-site occupancy.
Nat Commun, 13, 2022
7QSM
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BU of 7qsm by Molmil
Bovine complex I in lipid nanodisc, Deactive-ligand (composite)
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ...
Authors:Chung, I, Bridges, H.R, Hirst, J.
Deposit date:2022-01-13
Release date:2022-05-25
Last modified:2022-09-28
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Cryo-EM structures define ubiquinone-10 binding to mitochondrial complex I and conformational transitions accompanying Q-site occupancy.
Nat Commun, 13, 2022
7QSN
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BU of 7qsn by Molmil
Bovine complex I in lipid nanodisc, Deactive-apo
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ...
Authors:Chung, I, Bridges, H.R, Hirst, J.
Deposit date:2022-01-13
Release date:2022-05-25
Last modified:2022-09-28
Method:ELECTRON MICROSCOPY (2.81 Å)
Cite:Cryo-EM structures define ubiquinone-10 binding to mitochondrial complex I and conformational transitions accompanying Q-site occupancy.
Nat Commun, 13, 2022
7QSK
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BU of 7qsk by Molmil
Bovine complex I in lipid nanodisc, Active-Q10
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ...
Authors:Chung, I, Bridges, H.R, Hirst, J.
Deposit date:2022-01-13
Release date:2022-05-25
Last modified:2022-09-28
Method:ELECTRON MICROSCOPY (2.84 Å)
Cite:Cryo-EM structures define ubiquinone-10 binding to mitochondrial complex I and conformational transitions accompanying Q-site occupancy.
Nat Commun, 13, 2022
7ZMB
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BU of 7zmb by Molmil
CryoEM structure of mitochondrial complex I from Chaetomium thermophilum (state 2)
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ...
Authors:Laube, E, Kuehlbrandt, W.
Deposit date:2022-04-19
Release date:2022-11-30
Last modified:2022-12-07
Method:ELECTRON MICROSCOPY (2.75 Å)
Cite:Conformational changes in mitochondrial complex I of the thermophilic eukaryote Chaetomium thermophilum.
Sci Adv, 8, 2022
7QSO
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BU of 7qso by Molmil
Bovine complex I in lipid nanodisc, State 3 (Slack)
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ...
Authors:Chung, I, Bridges, H.R, Hirst, J.
Deposit date:2022-01-13
Release date:2022-05-25
Last modified:2022-09-28
Method:ELECTRON MICROSCOPY (3.02 Å)
Cite:Cryo-EM structures define ubiquinone-10 binding to mitochondrial complex I and conformational transitions accompanying Q-site occupancy.
Nat Commun, 13, 2022
7Z0S
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BU of 7z0s by Molmil
Structure of the Escherichia coli formate hydrogenlyase complex (anaerobic preparation, without formate dehydrogenase H)
Descriptor: 1-CIS-9-OCTADECANOYL-2-CIS-9-HEXADECANOYL PHOSPHATIDYL GLYCEROL, CARBONMONOXIDE-(DICYANO) IRON, CARDIOLIPIN, ...
Authors:Steinhilper, R, Murphy, B.J.
Deposit date:2022-02-23
Release date:2022-09-28
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structure of the membrane-bound formate hydrogenlyase complex from Escherichia coli.
Nat Commun, 13, 2022
7T30
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BU of 7t30 by Molmil
Structure of electron bifurcating Ni-Fe hydrogenase complex HydABCSL in FMN/NAD(H) bound state
Descriptor: CARBONMONOXIDE-(DICYANO) IRON, FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, ...
Authors:Feng, X, Li, H.
Deposit date:2021-12-06
Release date:2022-03-16
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structure and electron transfer pathways of an electron-bifurcating NiFe-hydrogenase.
Sci Adv, 8, 2022
7T2R
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BU of 7t2r by Molmil
Structure of electron bifurcating Ni-Fe hydrogenase complex HydABCSL in FMN-free apo state
Descriptor: CARBONMONOXIDE-(DICYANO) IRON, FE2/S2 (INORGANIC) CLUSTER, IRON/SULFUR CLUSTER, ...
Authors:Feng, X, Li, H.
Deposit date:2021-12-06
Release date:2022-03-16
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structure and electron transfer pathways of an electron-bifurcating NiFe-hydrogenase.
Sci Adv, 8, 2022
7TGH
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BU of 7tgh by Molmil
Cryo-EM structure of respiratory super-complex CI+III2 from Tetrahymena thermophila
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2 iron, ...
Authors:Zhou, L, Maldonado, M, Padavannil, A, Guo, F, Letts, J.A.
Deposit date:2022-01-07
Release date:2022-04-06
Last modified:2022-07-20
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structures of Tetrahymena 's respiratory chain reveal the diversity of eukaryotic core metabolism.
Science, 376, 2022
7R42
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BU of 7r42 by Molmil
Bovine complex I in the presence of IM1761092, active class ii (Composite map)
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ...
Authors:Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J.
Deposit date:2022-02-08
Release date:2023-02-08
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides.
Science, 379, 2023
7R4D
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BU of 7r4d by Molmil
Bovine complex I in the presence of IM1761092, deactive class vi (Composite map)
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ...
Authors:Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J.
Deposit date:2022-02-08
Release date:2023-02-08
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides.
Science, 379, 2023

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