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6YEV
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BU of 6yev by Molmil
Crystal structure of MsrA C206 and Trx C35S complex from Escherichia coli
Descriptor: Peptide methionine sulfoxide reductase MsrA, SODIUM ION, Thioredoxin 1
Authors:Napolitano, S, Zyla, D, Glockshuber, R.
Deposit date:2020-03-25
Release date:2021-04-07
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.94 Å)
Cite:Structure of a complex between the single-cysteine mutant MsrA C206 and Trx C35S from Escherichia coli
To Be Published
8S2N
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BU of 8s2n by Molmil
Xenorhabdus bovienii Rhs toxin TreTu complex with TrxA and TriTu immunity protein
Descriptor: Complete genome segment 11/17, DI(HYDROXYETHYL)ETHER, Immunity Protein TriX, ...
Authors:Jurenas, D, Terradot, L.
Deposit date:2024-02-18
Release date:2024-12-04
Last modified:2024-12-11
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Thioredoxin 1 moonlights as a chaperone for an interbacterial ADP-ribosyltransferase toxin.
Nat Commun, 15, 2024
8AON
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BU of 8aon by Molmil
Oxidoreductase fragment of human QSOX1 in complex with a Fab fragment of a humanized anti-QSOX1 antibody
Descriptor: GLYCEROL, Heavy chain, Light chain, ...
Authors:Khmelnitsky, L, Fass, D.
Deposit date:2022-08-08
Release date:2023-08-02
Last modified:2025-02-19
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Computational optimization of antibody humanness and stability by systematic energy-based ranking.
Nat Biomed Eng, 8, 2024
9GCO
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BU of 9gco by Molmil
Xenorhabdus bovienii Thioredoxin complex with Rhs toxin TreX and immunity protein TriX
Descriptor: CALCIUM ION, DI(HYDROXYETHYL)ETHER, Immunity Protein TriX, ...
Authors:Jurenas, D, Terradot, L.
Deposit date:2024-08-02
Release date:2024-12-04
Last modified:2024-12-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Thioredoxin 1 moonlights as a chaperone for an interbacterial ADP-ribosyltransferase toxin.
Nat Commun, 15, 2024
4LL4
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BU of 4ll4 by Molmil
The structure of the TRX and TXNIP complex
Descriptor: Thioredoxin, Thioredoxin-interacting protein
Authors:Hwang, J, Kim, M.H.
Deposit date:2013-07-09
Release date:2014-02-05
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The structural basis for the negative regulation of thioredoxin by thioredoxin-interacting protein
Nat Commun, 5, 2014
4LL1
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BU of 4ll1 by Molmil
The structure of the TRX and TXNIP complex
Descriptor: Thioredoxin, Thioredoxin-interacting protein
Authors:Hwang, J, Kim, M.H.
Deposit date:2013-07-09
Release date:2014-02-05
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:The structural basis for the negative regulation of thioredoxin by thioredoxin-interacting protein
Nat Commun, 5, 2014
5XOC
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BU of 5xoc by Molmil
Crystal structure of human Smad3-FoxH1 complex
Descriptor: Mothers against decapentaplegic homolog 3, Thioredoxin 1,Forkhead box protein H1
Authors:Miyazono, K, Ito, T, Tanokura, M.
Deposit date:2017-05-27
Release date:2018-03-28
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Hydrophobic patches on SMAD2 and SMAD3 determine selective binding to cofactors
Sci Signal, 11, 2018
5XWM
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BU of 5xwm by Molmil
human ERp44 zinc-bound form
Descriptor: CHLORIDE ION, Endoplasmic reticulum resident protein 44, ZINC ION
Authors:Watanabe, S, Harayama, M, Inaba, K.
Deposit date:2017-06-30
Release date:2019-01-02
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Zinc regulates ERp44-dependent protein quality control in the early secretory pathway.
Nat Commun, 10, 2019
8PKO
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BU of 8pko by Molmil
The ERAD misfolded glycoprotein checkpoint complex from Chaetomium thermophilum (EDEM:PDI heterodimer).
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Roversi, P, Hitchman, C.J, Lia, A, Bayo, Y.
Deposit date:2023-06-27
Release date:2024-07-10
Last modified:2025-07-09
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:The ERAD misfolded glycoprotein checkpoint complex from Chaetomium thermophilum (EDEM:PDI heterodimer).
To Be Published
7ZSC
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BU of 7zsc by Molmil
Crystal structure of the heterodimeric human C-P4H-II with truncated alpha subunit (C-P4H-II delta281)
Descriptor: Prolyl 4-hydroxylase subunit alpha-2, Protein disulfide-isomerase, SULFATE ION
Authors:Lebedev, A, Koski, M.K, Wierenga, R.K, Murthy, A.V, Sulu, R.
Deposit date:2022-05-06
Release date:2022-11-09
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (3.85 Å)
Cite:Crystal structure of the collagen prolyl 4-hydroxylase (C-P4H) catalytic domain complexed with PDI: Toward a model of the C-P4H alpha 2 beta 2 tetramer.
J.Biol.Chem., 298, 2022
7YSI
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BU of 7ysi by Molmil
Crystal structure of thioredoxin 2
Descriptor: Thiol disulfide reductase thioredoxin, ZINC ION
Authors:Chang, Y.J, Park, H.H.
Deposit date:2022-08-12
Release date:2023-03-15
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.202 Å)
Cite:Comparison of the structure and activity of thioredoxin 2 and thioredoxin 1 from Acinetobacter baumannii.
Iucrj, 10, 2023
8EKY
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BU of 8eky by Molmil
Cryo-EM structure of the human PRDX4-ErP46 complex
Descriptor: Peroxiredoxin-4, Thioredoxin domain-containing protein 5
Authors:Su, C.C.
Deposit date:2022-09-22
Release date:2023-05-03
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (3.47 Å)
Cite:High-resolution structural-omics of human liver enzymes.
Cell Rep, 42, 2023
6ENY
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BU of 6eny by Molmil
Structure of the human PLC editing module
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, Calreticulin, ...
Authors:Trowitzsch, S, Januliene, D, Blees, A, Moeller, A, Tampe, R.
Deposit date:2017-10-07
Release date:2017-11-29
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:Structure of the human MHC-I peptide-loading complex.
Nature, 551, 2017
8EOJ
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BU of 8eoj by Molmil
Microsomal triglyceride transfer protein
Descriptor: Microsomal triglyceride transfer protein large subunit, Protein disulfide-isomerase
Authors:Zhang, Z.
Deposit date:2022-10-03
Release date:2023-05-03
Last modified:2024-11-20
Method:ELECTRON MICROSCOPY (3.07 Å)
Cite:High-resolution structural-omics of human liver enzymes.
Cell Rep, 42, 2023
5AYK
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BU of 5ayk by Molmil
Crystal structure of ERdj5 form I
Descriptor: 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, CHLORIDE ION, DnaJ homolog subfamily C member 10
Authors:Watanabe, S, Maegawa, K, Inaba, K.
Deposit date:2015-08-22
Release date:2017-02-15
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Highly dynamic nature of ERdj5 is essential for enhancement of the ER associated degradation
To Be Published
5AYL
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BU of 5ayl by Molmil
Crystal structure of ERdj5 form II
Descriptor: 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, DnaJ homolog subfamily C member 10
Authors:Watanabe, S, Maegawa, K, Inaba, K.
Deposit date:2015-08-22
Release date:2017-02-15
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Highly dynamic nature of ERdj5 is essential for enhancement of the ER associated degradation
To Be Published
5XF7
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BU of 5xf7 by Molmil
Crystal structure of human protein disulfide isomerase-like protein of the testis
Descriptor: Protein disulfide-isomerase-like protein of the testis
Authors:Li, H, Li, J, Liu, Y, Liang, H.
Deposit date:2017-04-08
Release date:2017-12-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.381 Å)
Cite:Crystal and solution structures of human protein-disulfide isomerase-like protein of the testis (PDILT) provide insight into its chaperone activity
J. Biol. Chem., 293, 2018
2IPA
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BU of 2ipa by Molmil
solution structure of Trx-ArsC complex
Descriptor: Protein arsC, Thioredoxin
Authors:Jin, C, Hu, Y, Li, Y, Zhang, X.
Deposit date:2006-10-12
Release date:2007-02-13
Last modified:2024-11-13
Method:SOLUTION NMR
Cite:Conformational fluctuations coupled to the thiol-disulfide transfer between thioredoxin and arsenate reductase in Bacillus subtilis.
J.Biol.Chem., 282, 2007
6Y4Z
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BU of 6y4z by Molmil
The crystal structure of human MACROD2 in space group P43212
Descriptor: L(+)-TARTARIC ACID, Thioredoxin 1,ADP-ribose glycohydrolase MACROD2
Authors:Wazir, S, Maksimainen, M.M, Lehtio, L.
Deposit date:2020-02-24
Release date:2020-09-30
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Multiple crystal forms of human MacroD2.
Acta Crystallogr.,Sect.F, 76, 2020
6Y4Y
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BU of 6y4y by Molmil
The crystal structure of human MACROD2 in space group P41212
Descriptor: L(+)-TARTARIC ACID, Thioredoxin 1,ADP-ribose glycohydrolase MACROD2
Authors:Wazir, S, Maksimainen, M.M, Lehtio, L.
Deposit date:2020-02-24
Release date:2020-09-30
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Multiple crystal forms of human MacroD2.
Acta Crystallogr.,Sect.F, 76, 2020
7SCD
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BU of 7scd by Molmil
Ternary complex of fixed-arm Trx-3ost5 (I299E) with 8mer-1 octasaccharide substrate and co-factor product PAP
Descriptor: 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid, ADENOSINE-3'-5'-DIPHOSPHATE, Thioredoxin 1,Heparan sulfate glucosamine 3-O-sulfotransferase 5
Authors:Wander, R, Kaminski, A.M, Krahn, J.M, Liu, J, Pedersen, L.C.
Deposit date:2021-09-27
Release date:2022-01-19
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural and Substrate Specificity Analysis of 3-O-Sulfotransferase Isoform 5 to Synthesize Heparan Sulfate
Acs Catalysis, 11, 2021
7SCE
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BU of 7sce by Molmil
Ternary complex of fixed-arm Trx-3ost5 (I299E) with 8mer-2 octasaccharide substrate and co-factor product PAP
Descriptor: 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, ADENOSINE-3'-5'-DIPHOSPHATE, Thioredoxin 1,Heparan sulfate glucosamine 3-O-sulfotransferase 5
Authors:Wander, R, Kaminski, A.M, Krahn, J.M, Liu, J, Pedersen, L.C.
Deposit date:2021-09-27
Release date:2022-01-19
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural and Substrate Specificity Analysis of 3-O-Sulfotransferase Isoform 5 to Synthesize Heparan Sulfate
Acs Catalysis, 11, 2021
7P9D
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BU of 7p9d by Molmil
Crystal structure of Chlamydomonas reinhardtii NADPH Dependent Thioredoxin Reductase 1 domain
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Thioredoxin reductase
Authors:Singh, R.K, Marchetti, G.M, Hippler, M, Kuemmel, D.
Deposit date:2021-07-27
Release date:2022-01-12
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Structural analysis revealed a novel conformation of the NTRC reductase domain from Chlamydomonas reinhardtii.
J.Struct.Biol., 214, 2021
7P9E
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BU of 7p9e by Molmil
Chlamydomonas reinhardtii NADPH Dependent Thioredoxin Reductase 1 domain CS mutant
Descriptor: 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, FLAVIN-ADENINE DINUCLEOTIDE, Thioredoxin reductase
Authors:Fuesser, F, Kuemmel, D.
Deposit date:2021-07-27
Release date:2022-01-19
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Structural analysis revealed a novel conformation of the NTRC reductase domain from Chlamydomonas reinhardtii.
J.Struct.Biol., 214, 2021
7K58
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BU of 7k58 by Molmil
Structure of outer-arm dyneins bound to microtubule with microtubule binding state 1(MTBS-1)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Dynein heavy chain, ...
Authors:Qinhui, R, Kai, Z.
Deposit date:2020-09-16
Release date:2021-09-29
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structures of outer-arm dynein array on microtubule doublet reveal a motor coordination mechanism.
Nat.Struct.Mol.Biol., 28, 2021

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PDB entries from 2025-07-09

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