5US1
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![BU of 5us1 by Molmil](/molmil-images/mine/5us1) | Crystal structure of aminoglycoside acetyltransferase AAC(2')-Ia in complex with N2'-acetylgentamicin C1A and coenzyme A | Descriptor: | (1R,2S,3S,4R,6S)-4,6-diamino-3-{[3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl]oxy}-2-hydroxycyclohexyl 2-(acetylamino)-6-amino-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranoside, ACETYL COENZYME *A, Aminoglycoside 2'-N-acetyltransferase, ... | Authors: | Stogios, P.J, Evdokimova, E, Xu, Z, Wawrzak, Z, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2017-02-13 | Release date: | 2017-03-15 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.48 Å) | Cite: | Plazomicin Retains Antibiotic Activity against Most Aminoglycoside Modifying Enzymes. ACS Infect Dis, 4, 2018
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2REF
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3EXN
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![BU of 3exn by Molmil](/molmil-images/mine/3exn) | Crystal structure of acetyltransferase from Thermus thermophilus HB8 | Descriptor: | ACETYL COENZYME *A, CHLORIDE ION, Probable acetyltransferase | Authors: | Nocek, B, Hatzos, C, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2008-10-16 | Release date: | 2009-01-06 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of acetyltransferase from Thermus thermophilus HB8 To be Published
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2REE
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![BU of 2ree by Molmil](/molmil-images/mine/2ree) | |
3F8K
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![BU of 3f8k by Molmil](/molmil-images/mine/3f8k) | |
2DPT
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3D2P
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![BU of 3d2p by Molmil](/molmil-images/mine/3d2p) | Crystal structure of N-acetylglutamate synthase from Neisseria gonorrhoeae complexed with coenzyme A and L-arginine | Descriptor: | ARGININE, COENZYME A, Putative acetylglutamate synthase | Authors: | Shi, D, Min, L, Jin, Z, Allewell, N.M, Tuchman, M. | Deposit date: | 2008-05-08 | Release date: | 2008-12-23 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.56 Å) | Cite: | Mechanism of Allosteric Inhibition of N-Acetyl-L-glutamate Synthase by L-Arginine. J.Biol.Chem., 284, 2009
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2CXA
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![BU of 2cxa by Molmil](/molmil-images/mine/2cxa) | Crystal structure of Leucyl/phenylalanyl-tRNA protein transferase from Escherichia coli | Descriptor: | Leucyl/phenylalanyl-tRNA-protein transferase | Authors: | Kato-Murayama, M, Bessho, Y, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-06-28 | Release date: | 2005-12-28 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The crystal structure of leucyl/phenylalanyl-tRNA-protein transferase from Escherichia coli Protein Sci., 16, 2007
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2VEZ
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![BU of 2vez by Molmil](/molmil-images/mine/2vez) | AfGNA1 crystal structure complexed with Acetyl-CoA and Glucose-6P gives new insights into catalysis | Descriptor: | 6-O-phosphono-alpha-D-glucopyranose, ACETYL COENZYME *A, PHOSPHATE ION, ... | Authors: | Hurtado-Guerrero, R, Raimi, O, Shepherd, S, van Aalten, D.M.F. | Deposit date: | 2007-10-27 | Release date: | 2009-03-10 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Glucose-6-Phosphate as a Probe for the Glucosamine- 6-Phosphate N-Acetyltransferase Michaelis Complex. FEBS Lett., 581, 2007
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2EVN
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![BU of 2evn by Molmil](/molmil-images/mine/2evn) | NMR solution structures of At1g77540 | Descriptor: | Protein At1g77540 | Authors: | Tyler, R.C, Singh, S, Tonelli, M, Min, M.S, Markley, J.L, Center for Eukaryotic Structural Genomics (CESG) | Deposit date: | 2005-10-31 | Release date: | 2005-11-15 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structure of Arabidopsis thaliana At1g77540 Protein, a Minimal Acetyltransferase from the COG2388 Family. Biochemistry, 45, 2006
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2DPS
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3GG3
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![BU of 3gg3 by Molmil](/molmil-images/mine/3gg3) | Crystal Structure of the Bromodomain of Human PCAF | Descriptor: | CHLORIDE ION, Histone acetyltransferase PCAF | Authors: | Filippakopoulos, P, Keates, T, Picaud, S, Rehana, K, Fedorov, O, Ugochukwu, E, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2009-02-27 | Release date: | 2009-03-17 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Histone recognition and large-scale structural analysis of the human bromodomain family. Cell(Cambridge,Mass.), 149, 2012
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3D2M
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![BU of 3d2m by Molmil](/molmil-images/mine/3d2m) | Crystal structure of N-acetylglutamate synthase from Neisseria gonorrhoeae complexed with coenzyme A and L-glutamate | Descriptor: | COENZYME A, GLUTAMIC ACID, Putative acetylglutamate synthase | Authors: | Shi, D, Min, L, Jin, Z, Allewell, N.M, Tuchman, M. | Deposit date: | 2008-05-08 | Release date: | 2008-12-23 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Mechanism of Allosteric Inhibition of N-Acetyl-L-glutamate Synthase by L-Arginine. J.Biol.Chem., 284, 2009
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4IF5
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![BU of 4if5 by Molmil](/molmil-images/mine/4if5) | Structure of human Mec17 | Descriptor: | ACETYL COENZYME *A, Alpha-tubulin N-acetyltransferase, CHLORIDE ION | Authors: | Davenport, A.M, Collins, L, Minor, P, Sternberg, P, Hoelz, A. | Deposit date: | 2012-12-14 | Release date: | 2014-05-28 | Last modified: | 2014-07-02 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural and Functional Characterization of the alpha-Tubulin Acetyltransferase MEC-17. J.Mol.Biol., 426, 2014
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4BMH
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![BU of 4bmh by Molmil](/molmil-images/mine/4bmh) | Crystal structure of SsHAT | Descriptor: | ACETYLTRANSFERASE, CHLORIDE ION | Authors: | He, Y, Turkenburg, J.P, Davies, G.J. | Deposit date: | 2013-05-08 | Release date: | 2014-01-15 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Three-Dimensional Structure of a Streptomyces Sviceus Gnat Acetyltransferase with Similarity to the C-Terminal Domain of the Human Gh84 O-Glcnacase Acta Crystallogr.,Sect.D, 70, 2014
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4AVA
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![BU of 4ava by Molmil](/molmil-images/mine/4ava) | Crystal structure of protein lysine acetyltransferase Rv0998 from Mycobacterium tuberculosis | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, ACETYL COENZYME *A, ... | Authors: | Lee, H.J, Lang, P.T, Fortune, S.M, Sassetti, C.M, Alber, T. | Deposit date: | 2012-05-24 | Release date: | 2012-07-11 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.698 Å) | Cite: | Cyclic AMP Regulation of Protein Lysine Acetylation in Mycobacterium Tuberculosis. Nat.Struct.Mol.Biol., 19, 2012
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1OZP
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![BU of 1ozp by Molmil](/molmil-images/mine/1ozp) | Crystal Structure of Rv0819 from Mycobacterium tuberculosis MshD-Mycothiol Synthase Acetyl-Coenzyme A Complex. | Descriptor: | ACETYL COENZYME *A, hypothetical protein Rv0819 | Authors: | Vetting, M.W, Roderick, S.L, Yu, M, Blanchard, J.S. | Deposit date: | 2003-04-09 | Release date: | 2003-09-09 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of mycothiol synthase (Rv0819) from Mycobacterium tuberculosis shows structural homology to the GNAT family of N-acetyltransferases. Protein Sci., 12, 2003
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1P0H
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![BU of 1p0h by Molmil](/molmil-images/mine/1p0h) | Crystal Structure of Rv0819 from Mycobacterium Tuberculosis MshD-Mycothiol Synthase Coenzyme A Complex | Descriptor: | ACETYL COENZYME *A, COENZYME A, hypothetical protein Rv0819 | Authors: | Vetting, M.W, Roderick, S.L, Yu, M, Blanchard, J.S. | Deposit date: | 2003-04-10 | Release date: | 2003-09-09 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of mycothiol synthase (Rv0819) from Mycobacterium tuberculosis shows structural homology to the GNAT family of N-acetyltransferases. Protein Sci., 12, 2003
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1FY7
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![BU of 1fy7 by Molmil](/molmil-images/mine/1fy7) | CRYSTAL STRUCTURE OF YEAST ESA1 HISTONE ACETYLTRANSFERASE DOMAIN COMPLEXED WITH COENZYME A | Descriptor: | COENZYME A, ESA1 HISTONE ACETYLTRANSFERASE, SODIUM ION | Authors: | Yan, Y, Barlev, N.A, Haley, R.H, Berger, S.L, Marmorstein, R. | Deposit date: | 2000-09-28 | Release date: | 2000-11-29 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of yeast Esa1 suggests a unified mechanism for catalysis and substrate binding by histone acetyltransferases. Mol.Cell, 6, 2000
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1I1D
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![BU of 1i1d by Molmil](/molmil-images/mine/1i1d) | CRYSTAL STRUCTURE OF YEAST GNA1 BOUND TO COA AND GLNAC-6P | Descriptor: | 2-acetamido-2-deoxy-6-O-phosphono-alpha-D-glucopyranose, COENZYME A, GLUCOSAMINE-PHOSPHATE N-ACETYLTRANSFERASE, ... | Authors: | Peneff, C, Mengin-Lecreulx, D, Bourne, Y. | Deposit date: | 2001-02-01 | Release date: | 2001-05-16 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The crystal structures of Apo and complexed Saccharomyces cerevisiae GNA1 shed light on the catalytic mechanism of an amino-sugar N-acetyltransferase. J.Biol.Chem., 276, 2001
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1I12
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7K09
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![BU of 7k09 by Molmil](/molmil-images/mine/7k09) | Puromycin N-acetyltransferase in complex with acetyl-CoA | Descriptor: | ACETYL COENZYME *A, Puromycin N-acetyltransferase | Authors: | Caputo, A.T, Newman, J, Adams, T.E, Peat, T.S. | Deposit date: | 2020-09-03 | Release date: | 2021-03-17 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.313 Å) | Cite: | Structure-guided selection of puromycin N-acetyltransferase mutants with enhanced selection stringency for deriving mammalian cell lines expressing recombinant proteins. Sci Rep, 11, 2021
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7K0A
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![BU of 7k0a by Molmil](/molmil-images/mine/7k0a) | Puromycin N-acetyltransferase in complex with acetylated puromycin and CoA | Descriptor: | 1,2-ETHANEDIOL, COENZYME A, DI(HYDROXYETHYL)ETHER, ... | Authors: | Peat, T.S, Caputo, A.T, Newman, J, Adams, T.E. | Deposit date: | 2020-09-03 | Release date: | 2021-03-17 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure-guided selection of puromycin N-acetyltransferase mutants with enhanced selection stringency for deriving mammalian cell lines expressing recombinant proteins. Sci Rep, 11, 2021
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7KWX
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![BU of 7kwx by Molmil](/molmil-images/mine/7kwx) | Spermidine N-acetyltransferase SpeG N152L mutant from Vibrio cholerae | Descriptor: | Spermidine N(1)-acetyltransferase | Authors: | Le, V.T.B, Tsimbalyuk, S, Lim, E.Q, Solis, A, Gawat, D, Boeck, P, Renolo, R, Forwood, J.K, Kuhn, M.L. | Deposit date: | 2020-12-02 | Release date: | 2020-12-16 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.42 Å) | Cite: | The Vibrio cholerae SpeG Spermidine/Spermine N -Acetyltransferase Allosteric Loop and beta 6-beta 7 Structural Elements Are Critical for Kinetic Activity. Front Mol Biosci, 8, 2021
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7KYJ
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![BU of 7kyj by Molmil](/molmil-images/mine/7kyj) | Structure of a GNAT superfamily PA3944 acetyltransferase in complex with zinc | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, Acetyltransferase PA3944, ... | Authors: | Czub, M.P, Porebski, P.J, Cymborowski, M, Shabalin, I.G, Reidl, C.T, Becker, D.P, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2020-12-07 | Release date: | 2020-12-16 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of a GNAT superfamily PA3944 acetyltransferase in complex with zinc To Be Published
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