8AGW
| Yeast RQC complex in state D | Descriptor: | 25S rRNA, 5.8S rRNA, 5S rRNA, ... | Authors: | Tesina, P, Buschauer, R, Beckmann, R. | Deposit date: | 2022-07-20 | Release date: | 2023-03-08 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control. Mol.Cell, 83, 2023
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7ZM7
| CryoEM structure of mitochondrial complex I from Chaetomium thermophilum (inhibited by DDM) | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | Authors: | Laube, E, Kuehlbrandt, W. | Deposit date: | 2022-04-19 | Release date: | 2022-11-30 | Last modified: | 2022-12-07 | Method: | ELECTRON MICROSCOPY (2.77 Å) | Cite: | Conformational changes in mitochondrial complex I of the thermophilic eukaryote Chaetomium thermophilum. Sci Adv, 8, 2022
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8A3D
| Human mature large subunit of the ribosome with eIF6 and homoharringtonine bound | Descriptor: | (3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine, 28S ribosomal RNA, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | Authors: | Faille, A, Warren, A.J, Dent, K.C. | Deposit date: | 2022-06-08 | Release date: | 2023-03-08 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (1.67 Å) | Cite: | The chemical landscape of the human ribosome at 1.67 angstrom resolution. Biorxiv, 2023
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7ZTA
| Structure of an Escherichia coli 70S ribosome stalled by Tetracenomycin X during translation of an MAAAPQK(C) peptide | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Leroy, E.C, Perry, T.N, Renault, T.T, Innis, C.A. | Deposit date: | 2022-05-09 | Release date: | 2023-04-12 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Tetracenomycin X sequesters peptidyl-tRNA during translation of QK motifs. Nat.Chem.Biol., 19, 2023
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8BF9
| Molecular view of ER membrane remodeling by the Sec61/TRAP translocon. | Descriptor: | 60S ribosomal protein L39, Large ribosomal subunit protein eL31, Large ribosomal subunit protein eL38, ... | Authors: | Karki, S, Javanainen, M, Tranter, D, Rehan, S, Huiskonen, J, Happonen, L, Paavilainen, V. | Deposit date: | 2022-10-24 | Release date: | 2023-11-01 | Last modified: | 2023-12-20 | Method: | ELECTRON MICROSCOPY (2.69 Å) | Cite: | Molecular view of ER membrane remodeling by the Sec61/TRAP translocon. Embo Rep., 24, 2023
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4XP7
| Crystal structure of Human tRNA dihydrouridine synthase 2 | Descriptor: | 1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL, tRNA-dihydrouridine(20) synthase [NAD(P)+]-like | Authors: | Whelan, F, Jenkins, H.T, Griffiths, S, Byrne, R.T, Dodson, E.J, Antson, A.A. | Deposit date: | 2015-01-16 | Release date: | 2015-01-28 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | From bacterial to human dihydrouridine synthase: automated structure determination. Acta Crystallogr.,Sect.D, 71, 2015
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3W9Z
| Crystal structure of DusC | Descriptor: | FLAVIN MONONUCLEOTIDE, tRNA-dihydrouridine synthase C | Authors: | Chen, M, Yu, J, Tanaka, Y, Tanaka, I, Yao, M. | Deposit date: | 2013-04-19 | Release date: | 2013-07-31 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of dihydrouridine synthase C (DusC) from Escherichia coli Acta Crystallogr.,Sect.F, 69, 2013
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4BF9
| Crystal structure of E. coli dihydrouridine synthase C (DusC) (selenomethionine derivative) | Descriptor: | FLAVIN MONONUCLEOTIDE, TRNA-DIHYDROURIDINE SYNTHASE C | Authors: | Byrne, R.T, Whelan, F, Konevega, A, Aziz, N, Rodnina, M, Antson, A.A. | Deposit date: | 2013-03-16 | Release date: | 2013-11-06 | Last modified: | 2015-05-27 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Major Reorientation of tRNA Substrates Defines Specificity of Dihydrouridine Synthases. Proc.Natl.Acad.Sci.USA, 112, 2015
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4BFA
| Crystal structure of E. coli dihydrouridine synthase C (DusC) | Descriptor: | 1,2-ETHANEDIOL, FLAVIN MONONUCLEOTIDE, NITRATE ION, ... | Authors: | Byrne, R.T, Whelan, F, Konevega, A, Aziz, N, Rodnina, M, Antson, A.A. | Deposit date: | 2013-03-16 | Release date: | 2013-11-06 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Major Reorientation of tRNA Substrates Defines Specificity of Dihydrouridine Synthases. Proc.Natl.Acad.Sci.USA, 112, 2015
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6EI9
| Crystal structure of E. coli tRNA-dihydrouridine synthase B (DusB) | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, FLAVIN MONONUCLEOTIDE, GLYCEROL, ... | Authors: | Bou-Nader, C, Hamdane, D. | Deposit date: | 2017-09-18 | Release date: | 2018-01-17 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Unveiling structural and functional divergences of bacterial tRNA dihydrouridine synthases: perspectives on the evolution scenario. Nucleic Acids Res., 46, 2018
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6EZA
| Crystal Structure of human tRNA-dihydrouridine(20) synthase catalytic domain E294K mutant | Descriptor: | CHLORIDE ION, FLAVIN MONONUCLEOTIDE, GLYCEROL, ... | Authors: | Bou-Nader, C, Bregeon, D, Pecqueur, L, Vincent, G, Fontecave, M, Hamdane, D. | Deposit date: | 2017-11-14 | Release date: | 2018-09-26 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Electrostatic Potential in the tRNA Binding Evolution of Dihydrouridine Synthases. Biochemistry, 57, 2018
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6EZB
| Crystal Structure of human tRNA-dihydrouridine(20) synthase catalytic domain Q305K mutant | Descriptor: | FLAVIN MONONUCLEOTIDE, GLYCEROL, SULFATE ION, ... | Authors: | Bou-Nader, C, Bregeon, D, Pecqueur, L, Fontecave, M, Hamdane, D. | Deposit date: | 2017-11-14 | Release date: | 2018-09-26 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Electrostatic Potential in the tRNA Binding Evolution of Dihydrouridine Synthases. Biochemistry, 57, 2018
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6EZC
| Crystal Structure of human tRNA-dihydrouridine(20) synthase catalytic domain E294K Q305K double mutant | Descriptor: | CHLORIDE ION, FLAVIN MONONUCLEOTIDE, GLYCEROL, ... | Authors: | Bou-Nader, C, Bregeon, D, Vincent, G, Fontecave, M, Hamdane, D. | Deposit date: | 2017-11-14 | Release date: | 2018-09-26 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Electrostatic Potential in the tRNA Binding Evolution of Dihydrouridine Synthases. Biochemistry, 57, 2018
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4WFS
| Crystal Structure of tRNA-dihydrouridine(20) synthase catalytic domain | Descriptor: | CHLORIDE ION, FLAVIN MONONUCLEOTIDE, SULFATE ION, ... | Authors: | Bou-Nader, C, Pecqueur, L, Kamah, A, Bregeon, D, Golinelli-Pimpaneau, B, Guimaraes, B.G, Fontecave, M, Hamdane, D. | Deposit date: | 2014-09-17 | Release date: | 2015-10-07 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.68 Å) | Cite: | An extended dsRBD is required for post-transcriptional modification in human tRNAs. Nucleic Acids Res., 43, 2015
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3B0P
| tRNA-dihydrouridine synthase from Thermus thermophilus | Descriptor: | FLAVIN MONONUCLEOTIDE, tRNA-dihydrouridine synthase | Authors: | Yu, F, Tanaka, Y, Yamashita, K, Nakamura, A, Yao, M, Tanaka, I. | Deposit date: | 2011-06-12 | Release date: | 2011-12-14 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Molecular basis of dihydrouridine formation on tRNA Proc.Natl.Acad.Sci.USA, 108, 2011
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1VHN
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3B0U
| tRNA-dihydrouridine synthase from Thermus thermophilus in complex with tRNA fragment | Descriptor: | FLAVIN MONONUCLEOTIDE, RNA (5'-R(*GP*GP*(H2U)P*A)-3'), tRNA-dihydrouridine synthase | Authors: | Yu, F, Tanaka, Y, Yamashita, K, Nakamura, A, Yao, M, Tanaka, I. | Deposit date: | 2011-06-14 | Release date: | 2011-12-14 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.948 Å) | Cite: | Molecular basis of dihydrouridine formation on tRNA Proc.Natl.Acad.Sci.USA, 108, 2011
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3B0V
| tRNA-dihydrouridine synthase from Thermus thermophilus in complex with tRNA | Descriptor: | FLAVIN MONONUCLEOTIDE, tRNA, tRNA-dihydrouridine synthase | Authors: | Yu, F, Tanaka, Y, Yamashita, K, Nakamura, A, Yao, M, Tanaka, I. | Deposit date: | 2011-06-14 | Release date: | 2011-12-14 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (3.51 Å) | Cite: | Molecular basis of dihydrouridine formation on tRNA Proc.Natl.Acad.Sci.USA, 108, 2011
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