PDB: 7717 resultsInfo pagesStatus searchChemie searchBIRD

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8ELU	HRAS R97G Crystal form 1 Descriptor: CALCIUM ION, GTPase HRas, MAGNESIUM ION, ... Authors: Johnson, C.W, Rodrigues, J.A, Mattos, C. Deposit date: 2022-09-26 Release date: 2023-09-06 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.93 Å) Cite: Allosteric site variants affect GTP hydrolysis on Ras. Protein Sci., 32, 2023
8ELY	HRAS R97M Crystal Form 2 Descriptor: CALCIUM ION, GTPase HRas, MAGNESIUM ION, ... Authors: Johnson, C.W, Mattos, C. Deposit date: 2022-09-26 Release date: 2023-09-06 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Allosteric site variants affect GTP hydrolysis on Ras. Protein Sci., 32, 2023
8ELW	HRAS R97A Crystal Form 1 T-State Descriptor: CALCIUM ION, GTPase HRas, MAGNESIUM ION, ... Authors: Davis, K, Johnson, C.W, Mattos, C. Deposit date: 2022-09-26 Release date: 2023-09-06 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.699 Å) Cite: Allosteric site variants affect GTP hydrolysis on Ras. Protein Sci., 32, 2023
8ELS	HRAS R97A Crystal Form 1 R-state Descriptor: CALCIUM ION, GTPase HRas, MAGNESIUM ION, ... Authors: Davis, D, Johnson, C.W, Mattos, C. Deposit date: 2022-09-26 Release date: 2023-09-06 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.267 Å) Cite: Allosteric site variants affect GTP hydrolysis on Ras. Protein Sci., 32, 2023
8ELZ	HRAS R97M Crystal Form 1 Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CALCIUM ION, GTPase HRas, ... Authors: Johnson, C.W, Mattos, C. Deposit date: 2022-09-26 Release date: 2023-09-06 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.961 Å) Cite: Allosteric site variants affect GTP hydrolysis on Ras. Protein Sci., 32, 2023
8Q8C	Tau - AD-MIA10 (intermediate amyloid) Descriptor: Isoform Tau-D of Microtubule-associated protein tau Authors: Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M. Deposit date: 2023-08-18 Release date: 2023-09-06 Last modified: 2024-01-24 Method: ELECTRON MICROSCOPY (1.92 Å) Cite: Disease-specific tau filaments assemble via polymorphic intermediates. Nature, 625, 2024
8Q9F	Tau - CTE-LIA3 (tau intermediate amyloid) Descriptor: Isoform Tau-D of Microtubule-associated protein tau Authors: Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M. Deposit date: 2023-08-20 Release date: 2023-09-06 Last modified: 2024-01-17 Method: ELECTRON MICROSCOPY (1.91 Å) Cite: Disease-specific tau filaments assemble via polymorphic intermediates. Nature, 625, 2024
8Q9G	Tau - CTE-LIA5 (tau intermediate amyloid) Descriptor: Isoform Tau-D of Microtubule-associated protein tau Authors: Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M. Deposit date: 2023-08-20 Release date: 2023-09-06 Last modified: 2024-01-17 Method: ELECTRON MICROSCOPY (2.65 Å) Cite: Disease-specific tau filaments assemble via polymorphic intermediates. Nature, 625, 2024
8Q9J	Tau - CTE-LIA7 (tau intermediate amyloid) Descriptor: Isoform Tau-D of Microtubule-associated protein tau Authors: Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M. Deposit date: 2023-08-20 Release date: 2023-09-06 Last modified: 2024-01-17 Method: ELECTRON MICROSCOPY (2.96 Å) Cite: Disease-specific tau filaments assemble via polymorphic intermediates. Nature, 625, 2024
8Q9K	Tau - CTE-LIA13 (tau intermediate amyloid) Descriptor: Isoform Tau-D of Microtubule-associated protein tau Authors: Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M. Deposit date: 2023-08-20 Release date: 2023-09-06 Last modified: 2024-01-17 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Disease-specific tau filaments assemble via polymorphic intermediates. Nature, 625, 2024
8Q9M	Tau - CTE-type I (tau intermediate amyloid) Descriptor: Isoform Tau-D of Microtubule-associated protein tau Authors: Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M. Deposit date: 2023-08-20 Release date: 2023-09-06 Last modified: 2024-01-17 Method: ELECTRON MICROSCOPY (2.65 Å) Cite: Disease-specific tau filaments assemble via polymorphic intermediates. Nature, 625, 2024
8Q9L	Tau - CTE-LIA14 (tau intermediate amyloid) Descriptor: Isoform Tau-D of Microtubule-associated protein tau Authors: Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M. Deposit date: 2023-08-20 Release date: 2023-09-06 Last modified: 2024-01-17 Method: ELECTRON MICROSCOPY (2.76 Å) Cite: Disease-specific tau filaments assemble via polymorphic intermediates. Nature, 625, 2024
8Q9I	Tau - CTE-LIA6 (tau intermediate amyloid) Descriptor: Isoform Tau-D of Microtubule-associated protein tau Authors: Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M. Deposit date: 2023-08-20 Release date: 2023-09-06 Last modified: 2024-01-17 Method: ELECTRON MICROSCOPY (2.56 Å) Cite: Disease-specific tau filaments assemble via polymorphic intermediates. Nature, 625, 2024
8Q9O	CTE tau intermediate amyloid (LIA-17) Descriptor: Isoform Tau-D of Microtubule-associated protein tau Authors: Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M. Deposit date: 2023-08-20 Release date: 2023-09-06 Last modified: 2024-01-17 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Disease-specific tau filaments assemble via polymorphic intermediates. Nature, 625, 2024
8QCP	Tau - AD-LIA8 (tau intermediate amyloid) Descriptor: Isoform Tau-D of Microtubule-associated protein tau Authors: Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M. Deposit date: 2023-08-28 Release date: 2023-09-06 Last modified: 2024-01-24 Method: ELECTRON MICROSCOPY (3.21 Å) Cite: Disease-specific tau filaments assemble via polymorphic intermediates. Nature, 625, 2024
8QCR	Tau - CTE-MIA12 (tau intermediate amyloid) Descriptor: Isoform Tau-D of Microtubule-associated protein tau Authors: Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M. Deposit date: 2023-08-28 Release date: 2023-09-06 Last modified: 2024-01-17 Method: ELECTRON MICROSCOPY (2.75 Å) Cite: Disease-specific tau filaments assemble via polymorphic intermediates. Nature, 625, 2024
8ELK	HRAS R97F Crystal Form 1 Descriptor: CALCIUM ION, GTPase HRas, MAGNESIUM ION, ... Authors: Johnson, C.W, Mattos, C. Deposit date: 2022-09-26 Release date: 2023-09-06 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Allosteric site variants affect GTP hydrolysis on Ras. Protein Sci., 32, 2023
8ELX	HRAS R97I Crystal Form 1 Descriptor: CALCIUM ION, GTPase HRas, MAGNESIUM ION, ... Authors: Johnson, C.W, Mattos, C. Deposit date: 2022-09-26 Release date: 2023-09-06 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.975 Å) Cite: Allosteric site variants affect GTP hydrolysis on Ras. Protein Sci., 32, 2023
8E7E	Cryo-EM structure of cardiac amyloid fibril from a variant ATTR I84S amyloidosis patient Descriptor: Transthyretin Authors: Nguyen, B.A, Singh, V, Afrin, S, Saelices, L. Deposit date: 2022-08-23 Release date: 2023-08-30 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3.61 Å) Cite: Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy. Nat Commun, 15, 2024
8E7J	Cryo-EM structure of cardiac amyloid fibril from a variant ATTR I84S amyloidosis patient Descriptor: Transthyretin Authors: Nguyen, B.A, Saelices, L. Deposit date: 2022-08-24 Release date: 2023-08-30 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy. Nat Commun, 15, 2024
8CZ7	Crystal structure of SARS-CoV-2 Mpro with compound C2 Descriptor: 3C-like proteinase, N-[(4-chlorothiophen-2-yl)methyl]-2-(isoquinolin-4-yl)-N-(4-methoxyphenyl)acetamide Authors: Worrall, L.J, Lee, J, Strynadka, N.C.J. Deposit date: 2022-05-24 Release date: 2023-08-30 Method: X-RAY DIFFRACTION (2 Å) Cite: A novel class of broad-spectrum active-site-directed 3C-like protease inhibitors with nanomolar antiviral activity against highly immune-evasive SARS-CoV-2 Omicron subvariants. Emerg Microbes Infect, 12, 2023
8CYZ	Crystal structure of SARS-CoV-2 Mpro with compound C4 Descriptor: 3C-like proteinase, N-[(4-chlorothiophen-2-yl)methyl]-2-(isoquinolin-4-yl)-N-[4-(methylsulfanyl)phenyl]acetamide Authors: Worrall, L.J, Lee, J, Strynadka, N.C.J. Deposit date: 2022-05-24 Release date: 2023-08-30 Method: X-RAY DIFFRACTION (1.9 Å) Cite: A novel class of broad-spectrum active-site-directed 3C-like protease inhibitors with nanomolar antiviral activity against highly immune-evasive SARS-CoV-2 Omicron subvariants. Emerg Microbes Infect, 12, 2023
8CYU	Crystal structure of SARS-CoV-2 Mpro with compound C5 Descriptor: 3C-like proteinase, N-[(4-chlorothiophen-2-yl)methyl]-N-[4-(dimethylamino)phenyl]-2-(isoquinolin-4-yl)acetamide Authors: Worrall, L.J, Lee, J, Strynadka, N.C.J. Deposit date: 2022-05-24 Release date: 2023-08-30 Method: X-RAY DIFFRACTION (1.8 Å) Cite: A novel class of broad-spectrum active-site-directed 3C-like protease inhibitors with nanomolar antiviral activity against highly immune-evasive SARS-CoV-2 Omicron subvariants. Emerg Microbes Infect, 12, 2023
8CZ4	Crystal structure of SARS-CoV-2 Mpro with compound C3 Descriptor: 3C-like proteinase, N-(4-tert-butylphenyl)-N-[(4-chlorothiophen-2-yl)methyl]-2-(isoquinolin-4-yl)acetamide Authors: Worrall, L.J, Lee, J, Strynadka, N.C.J. Deposit date: 2022-05-24 Release date: 2023-08-30 Method: X-RAY DIFFRACTION (2.1 Å) Cite: A novel class of broad-spectrum active-site-directed 3C-like protease inhibitors with nanomolar antiviral activity against highly immune-evasive SARS-CoV-2 Omicron subvariants. Emerg Microbes Infect, 12, 2023
8Q8D	Tau - AD-LIA6 (tau intermediate amyloid) Descriptor: Isoform Tau-D of Microtubule-associated protein tau Authors: Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M. Deposit date: 2023-08-18 Release date: 2023-08-30 Last modified: 2024-01-24 Method: ELECTRON MICROSCOPY (3.04 Å) Cite: Disease-specific tau filaments assemble via polymorphic intermediates. Nature, 625, 2024

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