5ZAK
| Cryo-EM structure of human Dicer and its complexes with a pre-miRNA substrate | Descriptor: | Endoribonuclease Dicer, RISC-loading complex subunit TARBP2 | Authors: | Liu, Z, Wang, J, Cheng, H, Ke, X, Sun, L, Zhang, Q.C, Wang, H.-W. | Deposit date: | 2018-02-07 | Release date: | 2018-05-09 | Last modified: | 2019-11-06 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Cryo-EM Structure of Human Dicer and Its Complexes with a Pre-miRNA Substrate. Cell, 173, 2018
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6C90
| Human Mtr4 helicase in complex with ZCCHC8-CTD | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Exosome RNA helicase MTR4,Exosome RNA helicase MTR4, L(+)-TARTARIC ACID, ... | Authors: | Puno, M.R, Lima, C.D. | Deposit date: | 2018-01-25 | Release date: | 2018-05-30 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis for MTR4-ZCCHC8 interactions that stimulate the MTR4 helicase in the nuclear exosome-targeting complex. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5VHD
| DHX36 with an N-terminal truncation bound to ADP-AlF4 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DEAH (Asp-Glu-Ala-His) box polypeptide 36, TETRAFLUOROALUMINATE ION | Authors: | Chen, M, Ferre-D'Amare, A. | Deposit date: | 2017-04-13 | Release date: | 2018-06-13 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Structural basis of G-quadruplex unfolding by the DEAH/RHA helicase DHX36. Nature, 558, 2018
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5VHA
| DHX36 with an N-terminal truncation | Descriptor: | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | Authors: | Chen, M, Ferre-D'Amare, A. | Deposit date: | 2017-04-12 | Release date: | 2018-06-13 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.227 Å) | Cite: | Structural basis of G-quadruplex unfolding by the DEAH/RHA helicase DHX36. Nature, 558, 2018
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5VHC
| DHX36 with an N-terminal truncation bound to ADP-BeF3 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DEAH (Asp-Glu-Ala-His) box polypeptide 36, ... | Authors: | Chen, M, Ferre-D'Amare, A. | Deposit date: | 2017-04-12 | Release date: | 2018-06-13 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | Structural basis of G-quadruplex unfolding by the DEAH/RHA helicase DHX36. Nature, 558, 2018
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5VHE
| DHX36 in complex with the c-Myc G-quadruplex | Descriptor: | DEAH (Asp-Glu-Ala-His) box polypeptide 36, DNA (5'-D(*AP*GP*GP*GP*TP*GP*GP*GP*TP*AP*GP*GP*GP*TP*GP*GP*GP*TP*TP*TP*TP*TP*TP*T)-3'), POTASSIUM ION | Authors: | Chen, M, Ferre-D'Amare, A. | Deposit date: | 2017-04-13 | Release date: | 2018-06-13 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.793 Å) | Cite: | Structural basis of G-quadruplex unfolding by the DEAH/RHA helicase DHX36. Nature, 558, 2018
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6B4K
| Crystal structure of human DDX19B(AMPPNP) | Descriptor: | ATP-dependent RNA helicase DDX19B, MAGNESIUM ION, MALONATE ION, ... | Authors: | Lin, D.H, Correia, A.R, Cai, S.W, Huber, F.M, Jette, C.A, Hoelz, A. | Deposit date: | 2017-09-26 | Release date: | 2018-06-20 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural and functional analysis of mRNA export regulation by the nuclear pore complex. Nat Commun, 9, 2018
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6B4J
| Crystal structure of human Gle1 CTD-Nup42 GBM-DDX19B(AMPPNP) complex | Descriptor: | ATP-dependent RNA helicase DDX19B, MAGNESIUM ION, Nucleoporin GLE1, ... | Authors: | Lin, D.H, Correia, A.R, Cai, S.W, Huber, F.M, Jette, C.A, Hoelz, A. | Deposit date: | 2017-09-26 | Release date: | 2018-06-20 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Structural and functional analysis of mRNA export regulation by the nuclear pore complex. Nat Commun, 9, 2018
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6B4I
| Crystal structure of human Gle1 CTD-Nup42 GBM-DDX19B(ADP) complex | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase DDX19B, Nucleoporin GLE1, ... | Authors: | Lin, D.H, Correia, A.R, Cai, S.W, Huber, F.M, Jette, C.A, Hoelz, A. | Deposit date: | 2017-09-26 | Release date: | 2018-06-20 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3.619 Å) | Cite: | Structural and functional analysis of mRNA export regulation by the nuclear pore complex. Nat Commun, 9, 2018
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6D6R
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6D6Q
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6FA9
| CRYSTAL STRUCTURE OF THE DEAH-BOX HELICASE PRP2 | Descriptor: | Putative mRNA splicing factor, SULFATE ION | Authors: | Schmitt, A, Hamann, F, Neumann, P, Ficner, R. | Deposit date: | 2017-12-15 | Release date: | 2018-07-11 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of the spliceosomal DEAH-box ATPase Prp2. Acta Crystallogr D Struct Biol, 74, 2018
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6FAC
| CRYSTAL STRUCTURE OF THE DEAH-BOX HELICASE PRP2 IN COMPLEX WITH ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, MAGNESIUM ION, ... | Authors: | Schmitt, A, Hamann, F, Neumann, P, Ficner, R. | Deposit date: | 2017-12-15 | Release date: | 2018-07-11 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Crystal structure of the spliceosomal DEAH-box ATPase Prp2. Acta Crystallogr D Struct Biol, 74, 2018
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6FAA
| CRYSTAL STRUCTURE OF THE DEAH-BOX HELICASE PRP2 IN COMPLEX WITH ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ETHANOL, GLYCEROL, ... | Authors: | Schmitt, A, Hamann, F, Neumann, P, Ficner, R. | Deposit date: | 2017-12-15 | Release date: | 2018-07-11 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Crystal structure of the spliceosomal DEAH-box ATPase Prp2. Acta Crystallogr D Struct Biol, 74, 2018
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6FA5
| CRYSTAL STRUCTURE OF THE DEAH-BOX HELICASE PRP2 IN COMPLEX WITH ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... | Authors: | Hamann, F, Schmitt, A, Neumann, P, Ficner, R. | Deposit date: | 2017-12-15 | Release date: | 2018-07-11 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.303 Å) | Cite: | Crystal structure of the spliceosomal DEAH-box ATPase Prp2. Acta Crystallogr D Struct Biol, 74, 2018
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5YLZ
| Cryo-EM Structure of the Post-catalytic Spliceosome from Saccharomyces cerevisiae at 3.6 angstrom | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ... | Authors: | Wan, R, Yan, C, Bai, R, Lei, J, Shi, Y. | Deposit date: | 2017-10-20 | Release date: | 2018-07-18 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structure of the Post-catalytic Spliceosome from Saccharomyces cerevisiae Cell, 171, 2017
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5Y88
| Cryo-EM structure of the intron-lariat spliceosome ready for disassembly from S.cerevisiae at 3.5 angstrom | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, Intron lariat, ... | Authors: | Wan, R, Yan, C, Bai, R, Lei, J, Shi, Y. | Deposit date: | 2017-08-20 | Release date: | 2018-08-01 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.46 Å) | Cite: | Structure of an Intron Lariat Spliceosome from Saccharomyces cerevisiae Cell(Cambridge,Mass.), 171, 2017
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5YZG
| The Cryo-EM Structure of Human Catalytic Step I Spliceosome (C complex) at 4.1 angstrom resolution | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Zhan, X, Yan, C, Zhang, X, Lei, J, Shi, Y. | Deposit date: | 2017-12-14 | Release date: | 2018-08-08 | Last modified: | 2020-10-14 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Structure of a human catalytic step I spliceosome Science, 359, 2018
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6CZ5
| Crystal structure of small molecule AMP-acrylamide covalently bound to DDX3 S228C | Descriptor: | 5'-O-[(R)-hydroxy(propanoylamino)phosphoryl]adenosine, ATP-dependent RNA helicase DDX3X | Authors: | Barkovich, K.J, Moore, M.K, Hu, Q, Shokat, K.M. | Deposit date: | 2018-04-08 | Release date: | 2018-08-08 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Chemical genetic inhibition of DEAD-box proteins using covalent complementarity. Nucleic Acids Res., 46, 2018
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6GPG
| Structure of the RIG-I Singleton-Merten syndrome variant C268F | Descriptor: | MAGNESIUM ION, Probable ATP-dependent RNA helicase DDX58, RNA (5'-R(*CP*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*CP*G)-3'), ... | Authors: | Laessig, C, Lammens, K, Hopfner, K.-P. | Deposit date: | 2018-06-05 | Release date: | 2018-08-08 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.894 Å) | Cite: | Unified mechanisms for self-RNA recognition by RIG-I Singleton-Merten syndrome variants. Elife, 7, 2018
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6BB8
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5ZWO
| Cryo-EM structure of the yeast B complex at average resolution of 3.9 angstrom | Descriptor: | 13 kDa ribonucleoprotein-associated protein, 23 kDa U4/U6.U5 small nuclear ribonucleoprotein component, 66 kDa U4/U6.U5 small nuclear ribonucleoprotein component, ... | Authors: | Bai, R, Wan, R, Yan, C, Shi, Y. | Deposit date: | 2018-05-16 | Release date: | 2018-08-29 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structures of the fully assembledSaccharomyces cerevisiaespliceosome before activation Science, 360, 2018
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5ZWN
| Cryo-EM structure of the yeast pre-B complex at an average resolution of 3.3 angstrom (Part II: U1 snRNP region) | Descriptor: | 56 kDa U1 small nuclear ribonucleoprotein component, Pre-mRNA-processing factor 39, Pre-mRNA-splicing ATP-dependent RNA helicase PRP28, ... | Authors: | Bai, R, Wan, R, Yan, C, Lei, J, Shi, Y. | Deposit date: | 2018-05-16 | Release date: | 2018-08-29 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structures of the fully assembledSaccharomyces cerevisiaespliceosome before activation Science, 360, 2018
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5ZWM
| Cryo-EM structure of the yeast pre-B complex at an average resolution of 3.4~4.6 angstrom (tri-snRNP and U2 snRNP Part) | Descriptor: | 13 kDa ribonucleoprotein-associated protein, 66 kDa U4/U6.U5 small nuclear ribonucleoprotein component, Cold sensitive U2 snRNA suppressor 1, ... | Authors: | Bai, R, Wan, R, Yan, C, Lei, J, Shi, Y. | Deposit date: | 2018-05-16 | Release date: | 2018-08-29 | Last modified: | 2019-11-06 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structures of the fully assembledSaccharomyces cerevisiaespliceosome before activation Science, 360, 2018
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6DCR
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