4XWK
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![BU of 4xwk by Molmil](/molmil-images/mine/4xwk) | P-glycoprotein co-crystallized with BDE-100 | Descriptor: | 2,4-dibromophenyl 2,4,6-tribromophenyl ether, Multidrug resistance protein 1A | Authors: | McGrath, A.P, Rees, S.D, Chang, G. | Deposit date: | 2015-01-28 | Release date: | 2016-04-27 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Global marine pollutants inhibit P-glycoprotein: Environmental levels, inhibitory effects, and cocrystal structure. Sci Adv, 2, 2016
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6ETI
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![BU of 6eti by Molmil](/molmil-images/mine/6eti) | Structure of inhibitor-bound ABCG2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5D3(Fab) heavy chain variable domain, 5D3(Fab) light chain variable domain, ... | Authors: | Jackson, S.M, Manolaridis, I, Kowal, J, Zechner, M, Altmann, K.H, Locher, K.P. | Deposit date: | 2017-10-26 | Release date: | 2018-04-11 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural basis of small-molecule inhibition of human multidrug transporter ABCG2. Nat. Struct. Mol. Biol., 25, 2018
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5C78
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![BU of 5c78 by Molmil](/molmil-images/mine/5c78) | |
3B5X
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![BU of 3b5x by Molmil](/molmil-images/mine/3b5x) | Crystal Structure of MsbA from Vibrio cholerae | Descriptor: | Lipid A export ATP-binding/permease protein msbA | Authors: | Ward, A, Reyes, C.L, Yu, J, Roth, C.B, Chang, G. | Deposit date: | 2007-10-26 | Release date: | 2007-12-04 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (5.5 Å) | Cite: | Flexibility in the ABC transporter MsbA: Alternating access with a twist. Proc.Natl.Acad.Sci.Usa, 104, 2007
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4YMV
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![BU of 4ymv by Molmil](/molmil-images/mine/4ymv) | Crystal structure of an amino acid ABC transporter with ATPs | Descriptor: | ABC-type amino acid transport system, permease component, ABC-type polar amino acid transport system, ... | Authors: | Ge, J, Yu, J, Yang, M. | Deposit date: | 2015-03-07 | Release date: | 2015-04-22 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.003 Å) | Cite: | Structural basis for substrate specificity of an amino acid ABC transporter Proc.Natl.Acad.Sci.USA, 112, 2015
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6FFC
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![BU of 6ffc by Molmil](/molmil-images/mine/6ffc) | Structure of an inhibitor-bound ABC transporter | Descriptor: | ATP-binding cassette sub-family G member 2, ~{tert}-butyl 3-[(2~{S},5~{S},8~{S})-14-cyclopentyloxy-2-(2-methylpropyl)-4,7-bis(oxidanylidene)-3,6,17-triazatetracyclo[8.7.0.0^{3,8}.0^{11,16}]heptadeca-1(10),11,13,15-tetraen-5-yl]propanoate | Authors: | Jackson, S.M, Manolaridis, I, Kowal, J, Zechner, M, Taylor, N.M.I, Bause, M, Bauer, S, Bartholomaeus, R, Stahlberg, H, Bernhardt, G, Koenig, B, Buschauer, A, Altmann, K.H, Locher, K.P. | Deposit date: | 2018-01-06 | Release date: | 2018-04-11 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (3.56 Å) | Cite: | Structural basis of small-molecule inhibition of human multidrug transporter ABCG2. Nat. Struct. Mol. Biol., 25, 2018
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6FEQ
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![BU of 6feq by Molmil](/molmil-images/mine/6feq) | Structure of inhibitor-bound ABCG2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 5D3(Fab) heavy chain variable domain, 5D3(Fab) light chain variable domain, ... | Authors: | Jackson, S.M, Manolaridis, I, Kowal, J, Zechner, M, Altmann, K.H, Locher, K.P. | Deposit date: | 2018-01-03 | Release date: | 2018-04-11 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural basis of small-molecule inhibition of human multidrug transporter ABCG2. Nat. Struct. Mol. Biol., 25, 2018
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6FN4
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![BU of 6fn4 by Molmil](/molmil-images/mine/6fn4) | Apo form of UIC2 Fab complex of human-mouse chimeric ABCB1 (ABCB1HM) | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Apo form of Human-mouse chimeric ABCB1 (ABCB1HM) in complex with Antigen binding fragment of UIC2., ... | Authors: | Alam, A, Locher, K.P. | Deposit date: | 2018-02-02 | Release date: | 2018-02-21 | Last modified: | 2021-06-02 | Method: | ELECTRON MICROSCOPY (4.14 Å) | Cite: | Structure of a zosuquidar and UIC2-bound human-mouse chimeric ABCB1. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6FNP
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![BU of 6fnp by Molmil](/molmil-images/mine/6fnp) | Crystal structure of ECF-CbrT, a cobalamin transporter | Descriptor: | Energy-coupling factor transporter ATP-binding protein EcfA1, Energy-coupling factor transporter ATP-binding protein EcfA2, Energy-coupling factor transporter transmembrane protein EcfT, ... | Authors: | Santos, J.A, Rempel, S, Guskov, A, Slotboom, D.J. | Deposit date: | 2018-02-05 | Release date: | 2018-07-25 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Functional and structural characterization of an ECF-type ABC transporter for vitamin B12. Elife, 7, 2018
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4YMU
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![BU of 4ymu by Molmil](/molmil-images/mine/4ymu) | Crystal structure of an amino acid ABC transporter complex with arginines and ATPs | Descriptor: | ABC-type amino acid transport system, permease component, ABC-type polar amino acid transport system, ... | Authors: | Ge, J, Yu, J, Yang, M. | Deposit date: | 2015-03-07 | Release date: | 2015-04-22 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.503 Å) | Cite: | Structural basis for substrate specificity of an amino acid ABC transporter Proc.Natl.Acad.Sci.USA, 112, 2015
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4YMS
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![BU of 4yms by Molmil](/molmil-images/mine/4yms) | Crystal structure of an amino acid ABC transporter | Descriptor: | ABC-type amino acid transport system, permease component, ABC-type polar amino acid transport system, ... | Authors: | Ge, J, Yu, J, Yang, M. | Deposit date: | 2015-03-07 | Release date: | 2015-04-22 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis for substrate specificity of an amino acid ABC transporter Proc.Natl.Acad.Sci.USA, 112, 2015
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6GDI
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![BU of 6gdi by Molmil](/molmil-images/mine/6gdi) | Structure of P-glycoprotein(ABCB1) in the post-hydrolytic state | Descriptor: | Multidrug resistance protein 1A | Authors: | Ford, R.C, Thonghin, N, Collins, R.F, Barbieri, A, Shafi, T, Siebert, A. | Deposit date: | 2018-04-23 | Release date: | 2018-05-23 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (7.9 Å) | Cite: | Novel features in the structure of P-glycoprotein (ABCB1) in the post-hydrolytic state as determined at 7.9 angstrom resolution. Bmc Struct.Biol., 18, 2018
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3PUV
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![BU of 3puv by Molmil](/molmil-images/mine/3puv) | |
5B57
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![BU of 5b57 by Molmil](/molmil-images/mine/5b57) | Inward-facing conformation of ABC heme importer BhuUV from Burkholderia cenocepacia | Descriptor: | DECYL-BETA-D-MALTOPYRANOSIDE, Hemin import ATP-binding protein HmuV, Putative hemin ABC transport system, ... | Authors: | Naoe, Y, Nakamura, N, Doi, A, Shiro, Y, Sugimoto, H. | Deposit date: | 2016-04-25 | Release date: | 2016-11-16 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of bacterial haem importer complex in the inward-facing conformation Nat Commun, 7, 2016
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5D3M
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![BU of 5d3m by Molmil](/molmil-images/mine/5d3m) | Folate ECF transporter: AMPPNP bound state | Descriptor: | Energy-coupling factor transporter ATP-binding protein EcfA1, Energy-coupling factor transporter ATP-binding protein EcfA2, Energy-coupling factor transporter transmembrane protein EcfT, ... | Authors: | Guskov, A, Swier, L.J.Y.M, Slotboom, D.J. | Deposit date: | 2015-08-06 | Release date: | 2016-04-06 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.303 Å) | Cite: | Structural insight in the toppling mechanism of an energy-coupling factor transporter. Nat Commun, 7, 2016
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3BK7
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![BU of 3bk7 by Molmil](/molmil-images/mine/3bk7) | |
3B60
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![BU of 3b60 by Molmil](/molmil-images/mine/3b60) | Crystal Structure of MsbA from Salmonella typhimurium with AMPPNP, higher resolution form | Descriptor: | Lipid A export ATP-binding/permease protein msbA, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | Authors: | Ward, A, Reyes, C.L, Yu, J, Roth, C.B, Chang, G. | Deposit date: | 2007-10-26 | Release date: | 2007-12-04 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.7 Å) | Cite: | Flexibility in the ABC transporter MsbA: Alternating access with a twist. Proc.Natl.Acad.Sci.Usa, 104, 2007
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4YMW
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![BU of 4ymw by Molmil](/molmil-images/mine/4ymw) | Crystal structure of an amino acid ABC transporter with histidines | Descriptor: | ABC-type amino acid transport system, permease component, ABC-type polar amino acid transport system, ... | Authors: | Ge, J, Yu, J, Yang, M. | Deposit date: | 2015-03-07 | Release date: | 2015-04-22 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.804 Å) | Cite: | Structural basis for substrate specificity of an amino acid ABC transporter Proc.Natl.Acad.Sci.USA, 112, 2015
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6FN1
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![BU of 6fn1 by Molmil](/molmil-images/mine/6fn1) | Zosuquidar and UIC2 Fab complex of human-mouse chimeric ABCB1 (ABCB1HM) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Human-mouse chimeric ABCB1 (ABCBHM), UIC2 Antigen Binding Fragment Heavy Chain, ... | Authors: | Alam, A, Locher, K.P. | Deposit date: | 2018-02-02 | Release date: | 2018-02-21 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.58 Å) | Cite: | Structure of a zosuquidar and UIC2-bound human-mouse chimeric ABCB1. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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4YMT
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![BU of 4ymt by Molmil](/molmil-images/mine/4ymt) | Crystal structure of an amino acid ABC transporter complex with arginines | Descriptor: | ABC-type amino acid transport system, permease component, ABC-type polar amino acid transport system, ... | Authors: | Ge, J, Yu, J, Yang, M. | Deposit date: | 2015-03-07 | Release date: | 2015-04-22 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.599 Å) | Cite: | Structural basis for substrate specificity of an amino acid ABC transporter Proc.Natl.Acad.Sci.USA, 112, 2015
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3B5Y
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![BU of 3b5y by Molmil](/molmil-images/mine/3b5y) | Crystal Structure of MsbA from Salmonella typhimurium with AMPPNP | Descriptor: | Lipid A export ATP-binding/permease protein msbA, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | Authors: | Ward, A, Reyes, C.L, Yu, J, Roth, C.B, Chang, G. | Deposit date: | 2007-10-26 | Release date: | 2007-12-04 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (4.5 Å) | Cite: | Flexibility in the ABC transporter MsbA: Alternating access with a twist. Proc.Natl.Acad.Sci.Usa, 104, 2007
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3QF4
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![BU of 3qf4 by Molmil](/molmil-images/mine/3qf4) | Crystal structure of a heterodimeric ABC transporter in its inward-facing conformation | Descriptor: | ABC transporter, ATP-binding protein, MAGNESIUM ION, ... | Authors: | Hohl, M, Briand, C, Gruetter, M.G, Seeger, M.A. | Deposit date: | 2011-01-21 | Release date: | 2012-03-28 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of a heterodimeric ABC transporter in its inward-facing conformation Nat.Struct.Mol.Biol., 19, 2012
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5AWG
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![BU of 5awg by Molmil](/molmil-images/mine/5awg) | Crystal structure of Hg-bound SufB-SufC-SufD complex from Escherichia coli | Descriptor: | FeS cluster assembly protein SufB, FeS cluster assembly protein SufD, MERCURY (II) ION, ... | Authors: | Hirabayashi, K, Wada, K. | Deposit date: | 2015-07-03 | Release date: | 2015-11-11 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (4.278 Å) | Cite: | Functional Dynamics Revealed by the Structure of the SufBCD Complex, a Novel ATP-binding Cassette (ABC) Protein That Serves as a Scaffold for Iron-Sulfur Cluster Biogenesis J.Biol.Chem., 290, 2015
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5DO7
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![BU of 5do7 by Molmil](/molmil-images/mine/5do7) | Crystal Structure of the Human Sterol Transporter ABCG5/ABCG8 | Descriptor: | ATP-binding cassette sub-family G member 5, ATP-binding cassette sub-family G member 8 | Authors: | Lee, J.-Y, Kinch, L.N, Borek, D.M, Urbatsch, I.L, Xie, X.-S, Grishin, N.V, Cohen, J.C, Otwinowski, Z, Hobbs, H.H, Rosenbaum, D.M. | Deposit date: | 2015-09-10 | Release date: | 2016-05-11 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (3.93 Å) | Cite: | Crystal structure of the human sterol transporter ABCG5/ABCG8. Nature, 533, 2016
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3TUI
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![BU of 3tui by Molmil](/molmil-images/mine/3tui) | |