7OAP
 
 | | Nanobody H3 AND C1 bound to RBD | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, C1 nanobody, CHLORIDE ION, ... | | Authors: | Naismith, J.H, Mikolajek, H. | | Deposit date: | 2021-04-19 | | Release date: | 2021-08-11 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.901 Å) | | Cite: | A potent SARS-CoV-2 neutralising nanobody shows therapeutic efficacy in the Syrian golden hamster model of COVID-19.
Nat Commun, 12, 2021
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7OAN
 | | Nanobody C5 bound to Spike | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | | Authors: | Naismith, J.H, Weckener, M. | | Deposit date: | 2021-04-19 | | Release date: | 2021-08-11 | | Last modified: | 2021-10-06 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | A potent SARS-CoV-2 neutralising nanobody shows therapeutic efficacy in the Syrian golden hamster model of COVID-19.
Nat Commun, 12, 2021
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7OAY
 | | Nanobody F2 bound to RBD | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, F2 nanobody, Spike protein S1 | | Authors: | Naismith, J.H, Mikolajek, H. | | Deposit date: | 2021-04-20 | | Release date: | 2021-08-11 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.34 Å) | | Cite: | A potent SARS-CoV-2 neutralising nanobody shows therapeutic efficacy in the Syrian golden hamster model of COVID-19.
Nat Commun, 12, 2021
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7OAU
 | | Nanobody C5 bound to Kent variant RBD (N501Y) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, C5, GLYCEROL, ... | | Authors: | Naismith, J.H, Mikolajek, H. | | Deposit date: | 2021-04-20 | | Release date: | 2021-08-11 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | A potent SARS-CoV-2 neutralising nanobody shows therapeutic efficacy in the Syrian golden hamster model of COVID-19.
Nat Commun, 12, 2021
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6M1V
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6LVN
 | | Structure of the 2019-nCoV HR2 Domain | | Descriptor: | Spike protein S2' | | Authors: | Zhu, Y, Sun, F. | | Deposit date: | 2020-02-04 | | Release date: | 2020-02-26 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.47 Å) | | Cite: | Crystal structure of HR2 domain of 2019-nCoV S2 subunit
To Be Published
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7ZJL
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8A96
 | | SARS Cov2 Spike RBD in complex with Fab47 | | Descriptor: | Fab47 Heavy chain (variable domain), Fab47 Light chain (variable domain), Spike protein S1 | | Authors: | Hallberg, B.M, Das, H. | | Deposit date: | 2022-06-27 | | Release date: | 2023-05-03 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Immunoglobulin germline gene polymorphisms influence the function of SARS-CoV-2 neutralizing antibodies.
Immunity, 56, 2023
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8A99
 | | SARS Cov2 Spike in 1-up conformation complex with Fab47 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab47 (Heavy chain variable domain), ... | | Authors: | Hallberg, B.M, Das, H. | | Deposit date: | 2022-06-28 | | Release date: | 2023-05-10 | | Last modified: | 2023-09-27 | | Method: | ELECTRON MICROSCOPY (2.5 Å) | | Cite: | Immunoglobulin germline gene polymorphisms influence the function of SARS-CoV-2 neutralizing antibodies.
Immunity, 56, 2023
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8A94
 | | SARS CoV2 Spike in the 2-up state in complex with Fab47. | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab47 (Heavy chain Variable domain), ... | | Authors: | Hallberg, B.M, Das, H. | | Deposit date: | 2022-06-27 | | Release date: | 2023-05-03 | | Last modified: | 2023-07-26 | | Method: | ELECTRON MICROSCOPY (2.4 Å) | | Cite: | Immunoglobulin germline gene polymorphisms influence the function of SARS-CoV-2 neutralizing antibodies.
Immunity, 56, 2023
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8A95
 | | SARS Cov2 Spike RBD in complex with Fab47 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab47 (Heavy chain variable domain), ... | | Authors: | Hallberg, B.M, Das, H. | | Deposit date: | 2022-06-27 | | Release date: | 2023-08-16 | | Method: | ELECTRON MICROSCOPY (2.64 Å) | | Cite: | Immunoglobulin germline gene polymorphisms influence the function of SARS-CoV-2 neutralizing antibodies.
Immunity, 56, 2023
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8W4F
 | | SARS-CoV-2 spike protein in complex with a trivalent nanobody | | Descriptor: | Spike glycoprotein, Tribody | | Authors: | Jiang, X.Y, Qian, J.Q, Zhu, H.X, Qin, Q, Huang, Q. | | Deposit date: | 2023-08-24 | | Release date: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | Structure-guided design of a trivalent nanobody cluster targeting SARS-CoV-2 spike protein.
Int.J.Biol.Macromol., 256, 2024
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8VIF
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8VKE
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8VQ9
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8VQA
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8VQB
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8I3U
 | | Local CryoEM structure of the SARS-CoV-2 S6P in complex with 14B1 Fab | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Fab 14B1, Light chain of Fab 14B1, ... | | Authors: | Li, Z, Yu, F, Cao, S. | | Deposit date: | 2023-01-18 | | Release date: | 2023-10-04 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Broadly neutralizing antibodies derived from the earliest COVID-19 convalescents protect mice from SARS-CoV-2 variants challenge.
Signal Transduct Target Ther, 8, 2023
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8I3S
 | | Local CryoEM structure of the SARS-CoV-2 S6P in complex with 7B3 Fab | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain od Fab 7B3, Light chain of Fab 7B3, ... | | Authors: | Li, Z, Yu, F, Cao, S, ZHao, H. | | Deposit date: | 2023-01-17 | | Release date: | 2023-10-04 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Broadly neutralizing antibodies derived from the earliest COVID-19 convalescents protect mice from SARS-CoV-2 variants challenge.
Signal Transduct Target Ther, 8, 2023
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8HWT
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8HWS
 | | The complex structure of Omicron BA.4 RBD with BD604, S309, and S304 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, BD-604 Fab Heavy chain, BD-604 Fab Light chain, ... | | Authors: | He, Q.W, Xu, Z.P, Xie, Y.F. | | Deposit date: | 2023-01-02 | | Release date: | 2023-12-06 | | Method: | ELECTRON MICROSCOPY (2.36 Å) | | Cite: | An updated atlas of antibody evasion by SARS-CoV-2 Omicron sub-variants including BQ.1.1 and XBB.
Cell Rep Med, 4, 2023
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8I4F
 | | Omicron spike variant XBB with n3130v-Fc | | Descriptor: | Spike glycoprotein, n3130v-Fc | | Authors: | Hao, A.H, Zhang, X, Chen, Z.G, Sun, L. | | Deposit date: | 2023-01-19 | | Release date: | 2023-12-27 | | Method: | ELECTRON MICROSCOPY (3.44 Å) | | Cite: | Defining a highly conserved cryptic epitope for antibody recognition of SARS-CoV-2 variants.
Signal Transduct Target Ther, 8, 2023
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8I4G
 | | Omicron spike variant BQ.1.1 with n3130v-Fc | | Descriptor: | Spike glycoprotein, n3130v-Fc | | Authors: | Hao, A.H, Zhang, X, Chen, Z.G, Sun, L. | | Deposit date: | 2023-01-19 | | Release date: | 2023-12-27 | | Method: | ELECTRON MICROSCOPY (3.68 Å) | | Cite: | Defining a highly conserved cryptic epitope for antibody recognition of SARS-CoV-2 variants.
Signal Transduct Target Ther, 8, 2023
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8I4E
 | | Omicron spike variant XBB with Bn03 | | Descriptor: | Bn03, Spike glycoprotein | | Authors: | Hao, A.H, Zhang, X, Chen, Z.G, Sun, L. | | Deposit date: | 2023-01-19 | | Release date: | 2023-12-27 | | Method: | ELECTRON MICROSCOPY (3.98 Å) | | Cite: | Defining a highly conserved cryptic epitope for antibody recognition of SARS-CoV-2 variants.
Signal Transduct Target Ther, 8, 2023
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8HXJ
 | | BANAL-20-52 Spike trimer | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | | Authors: | Wang, X, Xu, G. | | Deposit date: | 2023-01-04 | | Release date: | 2024-01-10 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | The selective effect of fecal-oral transmission on the S proteins of bat SARS-CoV-2 related coronaviruses in favor of stability over infectivity
To Be Published
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