6Y5D
 
 | | Structure of human cGAS (K394E) bound to the nucleosome | | Descriptor: | Cyclic GMP-AMP synthase, DNA (153-MER), Histone H2A type 2-A, ... | | Authors: | Pathare, G.R, Cavadini, S, Kempf, G, Thoma, N.H. | | Deposit date: | 2020-02-25 | | Release date: | 2020-09-23 | | Last modified: | 2020-12-09 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Structural mechanism of cGAS inhibition by the nucleosome.
Nature, 587, 2020
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7PFX
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7PFF
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6FML
 | | CryoEM Structure INO80core Nucleosome complex | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin related protein 5, ... | | Authors: | Eustermann, S, Schall, K, Kostrewa, D, Strauss, M, Hopfner, K. | | Deposit date: | 2018-01-31 | | Release date: | 2018-04-25 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (4.34 Å) | | Cite: | Structural basis for ATP-dependent chromatin remodelling by the INO80 complex.
Nature, 556, 2018
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6X5A
 | | The mouse cGAS catalytic domain binding to human nucleosome that purified from HEK293T cells | | Descriptor: | Cyclic GMP-AMP synthase, DNA (natural), Histone H2A type 1, ... | | Authors: | Pengbiao, X, Pingwei, L, Baoyu, Z. | | Deposit date: | 2020-05-25 | | Release date: | 2020-09-16 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (4.36 Å) | | Cite: | The molecular basis of tight nuclear tethering and inactivation of cGAS.
Nature, 587, 2020
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7PFD
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7PFE
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7PFV
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6T7D
 | | Structure of human Sox11 transcription factor in complex with a nucleosome | | Descriptor: | DNA (151-MER), Histone H2A type 1-B/E, Histone H2B type 1-K, ... | | Authors: | Dodonova, S.O, Zhu, F, Dienemann, C, Taipale, J, Cramer, P. | | Deposit date: | 2019-10-21 | | Release date: | 2020-04-29 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (4.4 Å) | | Cite: | Nucleosome-bound SOX2 and SOX11 structures elucidate pioneer factor function.
Nature, 580, 2020
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7PEY
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7PEW
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8AV6
 | | CryoEM structure of INO80 core nucleosome complex in closed grappler conformation | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DASH complex subunit DAD4, ... | | Authors: | Kunert, F, Metzner, F.J, Eustermann, S, Jung, J, Woike, S, Schall, K, Kostrewa, D, Hopfner, K.P. | | Deposit date: | 2022-08-26 | | Release date: | 2022-12-14 | | Last modified: | 2022-12-28 | | Method: | ELECTRON MICROSCOPY (4.68 Å) | | Cite: | Structural mechanism of extranucleosomal DNA readout by the INO80 complex.
Sci Adv, 8, 2022
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7PFU
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7PEX
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7PF2
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6T7B
 | | Structure of human Sox2 transcription factor in complex with a nucleosome | | Descriptor: | DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-K, ... | | Authors: | Dodonova, S.O, Zhu, F, Dienemann, C, Taipale, J, Cramer, P. | | Deposit date: | 2019-10-21 | | Release date: | 2020-04-29 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (5.1 Å) | | Cite: | Nucleosome-bound SOX2 and SOX11 structures elucidate pioneer factor function.
Nature, 580, 2020
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7PFW
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7PEV
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7PFC
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6XJD
 | | Two mouse cGAS catalytic domain binding to human assembled nucleosome | | Descriptor: | Cyclic GMP-AMP synthase, DNA (145-MER), Histone H2A type 1, ... | | Authors: | Xu, P, Li, P, Zhao, B. | | Deposit date: | 2020-06-23 | | Release date: | 2020-09-16 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (6.8 Å) | | Cite: | The molecular basis of tight nuclear tethering and inactivation of cGAS.
Nature, 587, 2020
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7PEU
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7PEZ
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7PET
 | | The 4x177 nucleosome array containing H1 | | Descriptor: | DNA (702-MER), Histone H1.4, Histone H2A type 1-B/E, ... | | Authors: | Dombrowski, M, Cramer, P. | | Deposit date: | 2021-08-11 | | Release date: | 2022-08-03 | | Method: | ELECTRON MICROSCOPY (9.5 Å) | | Cite: | Histone H1 binding to nucleosome arrays depends on linker DNA length and trajectory.
Nat.Struct.Mol.Biol., 29, 2022
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7PFA
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7PFT
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