3PD6
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![BU of 3pd6 by Molmil](/molmil-images/mine/3pd6) | Crystal structure of mouse mitochondrial aspartate aminotransferase, a newly identified kynurenine aminotransferase-IV | Descriptor: | (2S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, Aspartate aminotransferase, ... | Authors: | Han, Q, Robinson, H, Cai, T, Tagle, D.A, Li, J. | Deposit date: | 2010-10-22 | Release date: | 2010-11-10 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Biochemical and structural characterization of mouse mitochondrial aspartate aminotransferase, a newly identified kynurenine aminotransferase-IV. Biosci.Rep., 31, 2011
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3PDB
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![BU of 3pdb by Molmil](/molmil-images/mine/3pdb) | Crystal structure of mouse mitochondrial aspartate aminotransferase in complex with oxaloacetic acid | Descriptor: | 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, Aspartate aminotransferase, mitochondrial, ... | Authors: | Han, Q, Robinson, H, Cai, T, Tagle, D.A, Li, J. | Deposit date: | 2010-10-22 | Release date: | 2010-11-10 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Biochemical and structural characterization of mouse mitochondrial aspartate aminotransferase, a newly identified kynurenine aminotransferase-IV. Biosci.Rep., 31, 2011
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3PDX
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![BU of 3pdx by Molmil](/molmil-images/mine/3pdx) | Crystal structural of mouse tyrosine aminotransferase | Descriptor: | Tyrosine aminotransferase | Authors: | Mehere, P.V, Han, Q, Lemkul, J.A, Robinson, H, Bevan, D.R, Li, J. | Deposit date: | 2010-10-25 | Release date: | 2010-11-03 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.91 Å) | Cite: | Tyrosine aminotransferase: biochemical and structural properties and molecular dynamics simulations. Protein Cell, 1, 2010
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1X0M
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![BU of 1x0m by Molmil](/molmil-images/mine/1x0m) | a Human Kynurenine Aminotransferase II Homologue from Pyrococcus horikoshii OT3 | Descriptor: | Aminotransferase II Homologue | Authors: | Chon, H, Matsumura, H, Koga, Y, Takano, K, Kanaya, S. | Deposit date: | 2005-03-24 | Release date: | 2005-04-12 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of a human kynurenine aminotransferase II homologue from Pyrococcus horikoshii OT3 at 2.20 A resolution Proteins, 61, 2005
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1X2A
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![BU of 1x2a by Molmil](/molmil-images/mine/1x2a) | Crystal Structure of e.coli AspAT complexed with N-phosphopyridoxyl-D-glutamic acid | Descriptor: | Aspartate aminotransferase, N-({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)-D-GLUTAMIC ACID | Authors: | Goto, M. | Deposit date: | 2005-04-21 | Release date: | 2005-06-14 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Binding of C5-dicarboxylic substrate to aspartate aminotransferase: implications for the conformational change at the transaldimination step. Biochemistry, 44, 2005
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1X28
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![BU of 1x28 by Molmil](/molmil-images/mine/1x28) | Crystal Structure of e.coli AspAT complexed with N-phosphopyridoxyl-L-glutamic acid | Descriptor: | Aspartate aminotransferase, N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)-L-glutamic acid | Authors: | Goto, M. | Deposit date: | 2005-04-21 | Release date: | 2005-06-14 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Binding of C5-dicarboxylic substrate to aspartate aminotransferase: implications for the conformational change at the transaldimination step. Biochemistry, 44, 2005
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1WST
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![BU of 1wst by Molmil](/molmil-images/mine/1wst) | Crystal structure of multiple substrate aminotransferase (MsAT) from Thermococcus profundus | Descriptor: | PYRIDOXAL-5'-PHOSPHATE, multiple substrate aminotransferase | Authors: | Lee, W.C, Manabe, F, Nemoto, N, Tamakoshi, M, Tanokura, M, Yamagishi, A. | Deposit date: | 2004-11-10 | Release date: | 2005-10-25 | Last modified: | 2021-11-10 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal structure of multiple substrate aminotransferase (MsAT) from Thermococcus profundus To be Published
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8H20
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![BU of 8h20 by Molmil](/molmil-images/mine/8h20) | Serine Palmitoyltransferase from Sphingobacterium multivorum complexed with Glycine | Descriptor: | 1,2-ETHANEDIOL, N-GLYCINE-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE], Serine palmitoyltransferase | Authors: | Murakami, T, Takahashi, A, Katayama, A, Miyahara, I, Kamiya, N, Ikushiro, H, Yano, T. | Deposit date: | 2022-10-04 | Release date: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structural insights into the substrate recognition of serine palmitoyltransferase from Sphingobacterium multivorum. J.Biol.Chem., 299, 2023
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8H21
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![BU of 8h21 by Molmil](/molmil-images/mine/8h21) | Serine Palmitoyltransferase from Sphingobacterium multivorum complexed with L-alanine | Descriptor: | 1,2-ETHANEDIOL, 2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-PROPIONIC ACID, Serine palmitoyltransferase | Authors: | Murakami, T, Takahashi, A, Katayama, A, Miyahara, I, Kamiya, N, Ikushiro, H, Yano, T. | Deposit date: | 2022-10-04 | Release date: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | Structural insights into the substrate recognition of serine palmitoyltransferase from Sphingobacterium multivorum. J.Biol.Chem., 299, 2023
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8H1W
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![BU of 8h1w by Molmil](/molmil-images/mine/8h1w) | Serine Palmitoyltransferase from Sphingobacterium multivorum | Descriptor: | 1,2-ETHANEDIOL, Serine palmitoyltransferase | Authors: | Takahashi, A, Murakami, T, Katayama, A, Miyahara, I, Kamiya, N, Ikushiro, H, Yano, T. | Deposit date: | 2022-10-04 | Release date: | 2023-08-16 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural insights into the substrate recognition of serine palmitoyltransferase from Sphingobacterium multivorum. J.Biol.Chem., 299, 2023
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8H1Q
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![BU of 8h1q by Molmil](/molmil-images/mine/8h1q) | Serine Palmitoyltransferase from Sphingobacterium multivorum complexed with L-serine | Descriptor: | 1,2-ETHANEDIOL, Serine palmitoyltransferase, [3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-SERINE | Authors: | Murakami, T, Takahashi, A, Katayama, A, Miyahara, I, Kamiya, N, Ikushiro, H, Yano, T. | Deposit date: | 2022-10-03 | Release date: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural insights into the substrate recognition of serine palmitoyltransferase from Sphingobacterium multivorum. J.Biol.Chem., 299, 2023
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1X29
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![BU of 1x29 by Molmil](/molmil-images/mine/1x29) | Crystal Structure of e.coli AspAT complexed with N-phosphopyridoxyl-2-methyl-L-glutamic acid | Descriptor: | Aspartate aminotransferase, N-({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)-2-METHYL-L-GLUTAMIC ACID | Authors: | Goto, M. | Deposit date: | 2005-04-21 | Release date: | 2005-06-14 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Binding of C5-dicarboxylic substrate to aspartate aminotransferase: implications for the conformational change at the transaldimination step. Biochemistry, 44, 2005
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8H29
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![BU of 8h29 by Molmil](/molmil-images/mine/8h29) | Serine Palmitoyltransferase from Sphingobacterium multivorum complexed with L-threonine | Descriptor: | 1,2-ETHANEDIOL, N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)-L-threonine, Serine palmitoyltransferase | Authors: | Murakami, T, Takahashi, A, Katayama, A, Miyahara, I, Kamiya, N, Ikushiro, H, Yano, T. | Deposit date: | 2022-10-05 | Release date: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structural insights into the substrate recognition of serine palmitoyltransferase from Sphingobacterium multivorum. J.Biol.Chem., 299, 2023
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8H1Y
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![BU of 8h1y by Molmil](/molmil-images/mine/8h1y) | Serine Palmitoyltransferase from Sphingobacterium multivorum complexed with L-homoserine | Descriptor: | (2~{S})-2-[[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylamino]-4-oxidanyl-butanoic acid, 1,2-ETHANEDIOL, Serine palmitoyltransferase | Authors: | Murakami, T, Takahashi, A, Katayama, A, Miyahara, I, Kamiya, N, Ikushiro, H, Yano, T. | Deposit date: | 2022-10-04 | Release date: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structural insights into the substrate recognition of serine palmitoyltransferase from Sphingobacterium multivorum. J.Biol.Chem., 299, 2023
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5T4L
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![BU of 5t4l by Molmil](/molmil-images/mine/5t4l) | PLP and GABA Trigger GabR-Mediated Transcription Regulation in Bacillus subsidies via External Aldimine Formation | Descriptor: | (4R)-4-amino-6-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}hexanoic acid, Aspartate aminotransferase | Authors: | Wu, R, Sanishvili, R, Belitsky, B.R, Juncosa, J.I, Le, H.V, Lehrer, H.J.S, Farley, M, Silverman, R.B, Petsko, G.A, Ringe, D, Liu, D. | Deposit date: | 2016-08-29 | Release date: | 2017-03-29 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.53 Å) | Cite: | PLP and GABA trigger GabR-mediated transcription regulation in Bacillus subtilis via external aldimine formation. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5T4K
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![BU of 5t4k by Molmil](/molmil-images/mine/5t4k) | PLP and GABA Trigger GabR-Mediated Transcription Regulation in Bacillus subsidies via External Aldimine Formation | Descriptor: | (4S)-5-fluoro-4-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]pentanoic acid, HTH-type transcriptional regulatory protein GabR | Authors: | Wu, R, Sanishvili, R, Belitsky, B.R, Juncosa, J.I, Le, H.V, Lehrer, H.J.S, Farley, M, Silverman, R.B, Petsko, G.A, Ringe, D, Liu, D. | Deposit date: | 2016-08-29 | Release date: | 2017-03-29 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.245 Å) | Cite: | PLP and GABA trigger GabR-mediated transcription regulation in Bacillus subtilis via external aldimine formation. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5TF5
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![BU of 5tf5 by Molmil](/molmil-images/mine/5tf5) | CRYSTAL STRUCTURE OF HUMAN KAT-2 IN COMPLEX WITH A REVERSIBLE INHIBITOR | Descriptor: | (2R)-2-(5,6-dichloro-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-phenylpropanoic acid, Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | Authors: | Nematollahi, A, Sun, G, Church, W.B. | Deposit date: | 2016-09-24 | Release date: | 2016-10-05 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.807 Å) | Cite: | Crystal structure and mechanistic analysis of a novel human kynurenine aminotransferase-2 reversible inhibitor Med.Chem.Res., 2017
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5TON
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![BU of 5ton by Molmil](/molmil-images/mine/5ton) | Crystal structure of AAT H143L mutant | Descriptor: | Aspartate aminotransferase, cytoplasmic | Authors: | Mueser, T.C, Dajnowicz, S, Kovalevsky, A. | Deposit date: | 2016-10-18 | Release date: | 2017-03-01 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Direct evidence that an extended hydrogen-bonding network influences activation of pyridoxal 5'-phosphate in aspartate aminotransferase. J. Biol. Chem., 292, 2017
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1YIY
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![BU of 1yiy by Molmil](/molmil-images/mine/1yiy) | Aedes aegypti kynurenine aminotransferase | Descriptor: | 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, BROMIDE ION, kynurenine aminotransferase; glutamine transaminase K | Authors: | Han, Q, Gao, Y.G, Robinson, H, Ding, H, Wilson, S, Li, J. | Deposit date: | 2005-01-13 | Release date: | 2005-05-10 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structures of Aedes aegypti kynurenine aminotransferase. FEBS J., 272, 2005
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1YIZ
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![BU of 1yiz by Molmil](/molmil-images/mine/1yiz) | Aedes aegypti kynurenine aminotrasferase | Descriptor: | BROMIDE ION, kynurenine aminotransferase; glutamine transaminase | Authors: | Han, Q, Gao, Y.G, Robinson, H, Ding, H, Wilson, S, Li, J. | Deposit date: | 2005-01-13 | Release date: | 2005-05-10 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Crystal structures of Aedes aegypti kynurenine aminotransferase. FEBS J., 272, 2005
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5TOR
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![BU of 5tor by Molmil](/molmil-images/mine/5tor) | Crystal structure of AAT D222T mutant | Descriptor: | Aspartate aminotransferase, cytoplasmic | Authors: | Mueser, T.C, Dajnowicz, S, Kovalevsky, A. | Deposit date: | 2016-10-18 | Release date: | 2017-03-01 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Direct evidence that an extended hydrogen-bonding network influences activation of pyridoxal 5'-phosphate in aspartate aminotransferase. J. Biol. Chem., 292, 2017
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5T4J
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![BU of 5t4j by Molmil](/molmil-images/mine/5t4j) | PLP and GABA Trigger GabR-Mediated Transcription Regulation in Bacillus subsidies via External Aldimine Formation | Descriptor: | GAMMA-AMINO-BUTANOIC ACID, HTH-type transcriptional regulatory protein GabR, PYRIDOXAL-5'-PHOSPHATE | Authors: | Wu, R, Sanishvili, R, Belitsky, B.R, Juncosa, J.I, Le, H.V, Lehrer, H.J.S, Farley, M, Silverman, R.B, Petsko, G.A, Ringe, D, Liu, D. | Deposit date: | 2016-08-29 | Release date: | 2017-03-29 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.231 Å) | Cite: | PLP and GABA trigger GabR-mediated transcription regulation in Bacillus subtilis via external aldimine formation. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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1YAA
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![BU of 1yaa by Molmil](/molmil-images/mine/1yaa) | |
1YOO
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![BU of 1yoo by Molmil](/molmil-images/mine/1yoo) | ASPARTATE AMINOTRANSFERASE MUTANT ATB17 WITH ISOVALERIC ACID | Descriptor: | ASPARTATE AMINOTRANSFERASE, ISOVALERIC ACID, PYRIDOXAL-5'-PHOSPHATE | Authors: | Oue, S, Okamoto, A, Yano, T, Kagamiyama, H. | Deposit date: | 1998-06-26 | Release date: | 1999-02-02 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Redesigning the substrate specificity of an enzyme by cumulative effects of the mutations of non-active site residues. J.Biol.Chem., 274, 1999
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5TXT
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![BU of 5txt by Molmil](/molmil-images/mine/5txt) | Structure of asymmetric apo/holo ALAS dimer from S. cerevisiae | Descriptor: | 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, 5-aminolevulinate synthase, mitochondrial, ... | Authors: | Brown, B.L, Grant, R.A, Kardon, J.R, Sauer, R.T, Baker, T.A. | Deposit date: | 2016-11-17 | Release date: | 2018-03-28 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure of the Mitochondrial Aminolevulinic Acid Synthase, a Key Heme Biosynthetic Enzyme. Structure, 26, 2018
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