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PDB: 43 results

8WAQ
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Structure of transcribing complex 7 (TC7), the initially transcribing complex with Pol II positioned 7nt downstream of TSS.
Descriptor: Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ...
Authors:Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y.
Deposit date:2023-09-08
Release date:2023-12-06
Last modified:2024-01-03
Method:ELECTRON MICROSCOPY (6.29 Å)
Cite:Structural visualization of transcription initiation in action.
Science, 382, 2023
8WAO
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BU of 8wao by Molmil
Structure of transcribing complex 5 (TC5), the initially transcribing complex with Pol II positioned 5nt downstream of TSS.
Descriptor: Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ...
Authors:Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y.
Deposit date:2023-09-07
Release date:2023-12-06
Last modified:2024-01-03
Method:ELECTRON MICROSCOPY (6.4 Å)
Cite:Structural visualization of transcription initiation in action.
Science, 382, 2023
7NW0
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BU of 7nw0 by Molmil
RNA polymerase II pre-initiation complex with open promoter DNA
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, CDK-activating kinase assembly factor MAT1, ...
Authors:Aibara, S, Schilbach, S, Cramer, P.
Deposit date:2021-03-16
Release date:2021-05-05
Last modified:2021-06-16
Method:ELECTRON MICROSCOPY (6.6 Å)
Cite:Structures of mammalian RNA polymerase II pre-initiation complexes.
Nature, 594, 2021
8EBV
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BU of 8ebv by Molmil
Initial DNA-lesion (AP) binding by XPC and TFIIH complex 1
Descriptor: CALCIUM ION, Centrin-2, DNA, ...
Authors:Kim, J, Yang, W.
Deposit date:2022-08-31
Release date:2023-04-19
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (7.1 Å)
Cite:Lesion recognition by XPC, TFIIH and XPA in DNA excision repair.
Nature, 617, 2023
6O9L
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BU of 6o9l by Molmil
Human holo-PIC in the closed state
Descriptor: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
Authors:Yan, C.L, Dodd, T, He, Y, Tainer, J.A, Tsutakawa, S.E, Ivanov, I.
Deposit date:2019-03-14
Release date:2019-05-29
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (7.2 Å)
Cite:Transcription preinitiation complex structure and dynamics provide insight into genetic diseases.
Nat.Struct.Mol.Biol., 26, 2019
7NVZ
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BU of 7nvz by Molmil
RNA polymerase II pre-initiation complex with closed promoter DNA in distal position
Descriptor: CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ...
Authors:Aibara, S, Schilbach, S, Cramer, P.
Deposit date:2021-03-16
Release date:2021-05-05
Last modified:2021-06-16
Method:ELECTRON MICROSCOPY (7.2 Å)
Cite:Structures of mammalian RNA polymerase II pre-initiation complexes.
Nature, 594, 2021
8WAR
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BU of 8war by Molmil
Structure of transcribing complex 8 (TC8), the initially transcribing complex with Pol II positioned 8nt downstream of TSS.
Descriptor: Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ...
Authors:Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y.
Deposit date:2023-09-08
Release date:2023-12-06
Last modified:2024-01-03
Method:ELECTRON MICROSCOPY (7.2 Å)
Cite:Structural visualization of transcription initiation in action.
Science, 382, 2023
7NVY
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BU of 7nvy by Molmil
RNA polymerase II pre-initiation complex with closed promoter DNA in proximal position
Descriptor: CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ...
Authors:Aibara, S, Schilbach, S, Cramer, P.
Deposit date:2021-03-16
Release date:2021-05-05
Last modified:2021-06-16
Method:ELECTRON MICROSCOPY (7.3 Å)
Cite:Structures of mammalian RNA polymerase II pre-initiation complexes.
Nature, 594, 2021
8WAL
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BU of 8wal by Molmil
Structure of transcribing complex 3 (TC3), the initially transcribing complex with Pol II positioned 3nt downstream of TSS.
Descriptor: Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ...
Authors:Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y.
Deposit date:2023-09-07
Release date:2023-12-06
Last modified:2024-01-03
Method:ELECTRON MICROSCOPY (8.52 Å)
Cite:Structural visualization of transcription initiation in action.
Science, 382, 2023
7BUL
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BU of 7bul by Molmil
Solution structure of the tandem PH and BSD1 domains of TFIIH p62
Descriptor: General transcription factor IIH subunit 1
Authors:Okuda, M, Nishimura, Y.
Deposit date:2020-04-07
Release date:2020-12-30
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural and dynamical insights into the PH domain of p62 in human TFIIH.
Nucleic Acids Res., 49, 2021
5GOW
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BU of 5gow by Molmil
Solution structure of the complex between DP1 acidic region and TFIIH p62 PH domain
Descriptor: DP1, General transcription factor IIH subunit 1
Authors:Okuda, M, Nishimura, Y.
Deposit date:2016-07-29
Release date:2016-12-07
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:The Interaction Mode of the Acidic Region of the Cell Cycle Transcription Factor DP1 with TFIIH
J. Mol. Biol., 428, 2016
5XV8
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BU of 5xv8 by Molmil
Solution structure of the complex between UVSSA acidic region and TFIIH p62 PH domain
Descriptor: General transcription factor IIH subunit 1, UV-stimulated scaffold protein A
Authors:Okuda, M, Nishimura, Y.
Deposit date:2017-06-27
Release date:2017-11-08
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Common TFIIH recruitment mechanism in global genome and transcription-coupled repair subpathways
Nucleic Acids Res., 45, 2017
2RUK
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BU of 2ruk by Molmil
Solution structure of the complex between p53 transactivation domain 2 and TFIIH p62 PH domain
Descriptor: Cellular tumor antigen p53, General transcription factor IIH subunit 1
Authors:Okuda, M, Nishimura, Y.
Deposit date:2014-09-24
Release date:2014-10-15
Last modified:2022-08-24
Method:SOLUTION NMR
Cite:Extended string binding mode of the phosphorylated transactivation domain of tumor suppressor p53.
J.Am.Chem.Soc., 136, 2014
2RNR
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BU of 2rnr by Molmil
Solution structure of the complex between TFIIE alpha C-terminal acidic domain and TFIIH p62 PH domain
Descriptor: TFIIH basal transcription factor complex p62 subunit, Transcription initiation factor IIE subunit alpha
Authors:Okuda, M, Nishimura, Y.
Deposit date:2008-01-31
Release date:2008-04-01
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structural insight into the TFIIE-TFIIH interaction: TFIIE and p53 share the binding region on TFIIH
Embo J., 27, 2008
2RVB
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BU of 2rvb by Molmil
Solution structure of the complex between XPC acidic domain and TFIIH p62 PH domain
Descriptor: DNA repair protein complementing XP-C cells, General transcription factor IIH subunit 1
Authors:Okuda, M, Nishimura, Y.
Deposit date:2015-07-01
Release date:2015-09-09
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural Insight into the Mechanism of TFIIH Recognition by the Acidic String of the Nucleotide Excision Repair Factor XPC.
Structure, 23, 2015
7DTI
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BU of 7dti by Molmil
Solution structure of the complex between RNA polymerase subunit RPB6 and TFIIH p62 PH domain
Descriptor: DNA-directed RNA polymerases I, II, and III subunit RPABC2, ...
Authors:Okuda, M, Nishimura, Y.
Deposit date:2021-01-05
Release date:2022-08-10
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Three human RNA polymerases interact with TFIIH via a common RPB6 subunit.
Nucleic Acids Res., 50, 2022
1PFJ
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BU of 1pfj by Molmil
Solution structure of the N-terminal PH/PTB domain of the TFIIH P62 subunit
Descriptor: TFIIH basal transcription factor complex p62 subunit
Authors:Gervais, V, Lamour, V, Jawhari, A, Frindel, F, Wasielewski, E, Thierry, J.C, Kieffer, B, Poterszman, A, Structural Proteomics in Europe (SPINE)
Deposit date:2003-05-27
Release date:2004-06-08
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:TFIIH contains a PH domain involved in DNA nucleotide excision repair.
Nat.Struct.Mol.Biol., 11, 2004
2DII
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BU of 2dii by Molmil
Solution structure of the BSD domain of human TFIIH basal transcription factor complex p62 subunit
Descriptor: TFIIH basal transcription factor complex p62 subunit
Authors:Yoneyama, M, Tochio, N, Koshiba, S, Watabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-03-30
Release date:2006-09-30
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the BSD domain of human TFIIH basal transcription factor complex p62 subunit
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