2RUK

Solution structure of the complex between p53 transactivation domain 2 and TFIIH p62 PH domain

Summary for 2RUK

• Entry DOI: 10.2210/pdb2ruk/pdb
• NMR Information: BMRB: 11578
• Descriptor: Cellular tumor antigen p53, General transcription factor IIH subunit 1 (2 entities in total)
• Functional Keywords: antitumor protein, general transcription factor, ph domain, transcription
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm. Isoform 1: Nucleus. Isoform 2: Nucleus. Isoform 3: Nucleus. Isoform 4: Nucleus. Isoform 7: Nucleus. Isoform 8: Nucleus. Isoform 9: Cytoplasm: P04637; Nucleus: P32780
• Total number of polymer chains: 2
• Total formula weight: 15175.05

Authors

Okuda, M.,Nishimura, Y. (deposition date: 2014-09-24, release date: 2014-10-15, Last modification date: 2022-08-24)

• Primary citation: Okuda, M.,Nishimura, Y.; Extended string binding mode of the phosphorylated transactivation domain of tumor suppressor p53.; J.Am.Chem.Soc., 136:14143-14152, 2014; PubMed: 25216154; DOI: 10.1021/ja506351f

Experimental method

SOLUTION NMR