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PDB: 528 件
4F8R
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BU of 4f8r by Molmil
Bacillus DNA Polymerase I Large Fragment complex 7
分子名称: DNA (5'-D(*CP*AP*TP*TP*CP*GP*AP*GP*TP*CP*AP*GP*G)-3'), DNA (5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(DDG))-3'), DNA polymerase, ...
著者Wang, W, Beese, L.S.
登録日2012-05-17
公開日2013-08-07
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Structures of a High-fidelity DNA Polymerase
to be published
3PX6
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BU of 3px6 by Molmil
Crystal Structure of Bacillus DNA Polymerase I Large Fragment Bound to DNA and ddCTP-dA Mismatch (tautomer) in Closed Conformation
分子名称: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, DNA (5'-D(*C*AP*TP*AP*GP*GP*AP*GP*TP*CP*AP*GP*G)-3'), DNA (5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(DOC))-3'), ...
著者Wang, W, Beese, L.S.
登録日2010-12-09
公開日2011-10-19
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Structural evidence for the rare tautomer hypothesis of spontaneous mutagenesis.
Proc.Natl.Acad.Sci.USA, 108, 2011
3PV8
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BU of 3pv8 by Molmil
Crystal Structure of Bacillus DNA Polymerase I Large Fragment Bound to DNA and ddTTP-dA in Closed Conformation
分子名称: 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*C*AP*TP*AP*AP*GP*AP*GP*TP*CP*AP*GP*G)-3'), DNA (5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(2DT))-3'), ...
著者Wang, W, Beese, L.S.
登録日2010-12-06
公開日2011-10-19
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献Structural evidence for the rare tautomer hypothesis of spontaneous mutagenesis.
Proc.Natl.Acad.Sci.USA, 108, 2011
3PX0
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BU of 3px0 by Molmil
Crystal Structure of Bacillus DNA Polymerase I Large Fragment Bound to DNA and dCTP-dA Mismatch (tautomer) in Closed Conformation
分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*C*AP*TP*AP*GP*GP*AP*GP*TP*CP*AP*GP*G)-3'), DNA (5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(DOC))-3'), ...
著者Wang, W, Beese, L.S.
登録日2010-12-09
公開日2011-10-19
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Structural evidence for the rare tautomer hypothesis of spontaneous mutagenesis.
Proc.Natl.Acad.Sci.USA, 108, 2011
3PS5
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BU of 3ps5 by Molmil
Crystal structure of the full-length Human Protein Tyrosine Phosphatase SHP-1
分子名称: SULFATE ION, Tyrosine-protein phosphatase non-receptor type 6
著者Wang, W, Liu, L, Song, X, Mo, Y, Komma, C, Bellamy, H.D, Zhao, Z.J, Zhou, G.W.
登録日2010-11-30
公開日2011-04-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal structure of human protein tyrosine phosphatase SHP-1 in the open conformation.
J.Cell.Biochem., 112, 2011
3PX4
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BU of 3px4 by Molmil
Crystal Structure of Bacillus DNA Polymerase I Large Fragment Bound to DNA and ddCTP-dA Mismatch (wobble) in Ajar Conformation
分子名称: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*TP*AP*GP*GP*AP*GP*TP*CP*AP*GP*G)-3'), DNA (5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(DOC))-3'), ...
著者Wang, W, Beese, L.S.
登録日2010-12-09
公開日2011-10-19
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.582 Å)
主引用文献Structural evidence for the rare tautomer hypothesis of spontaneous mutagenesis.
Proc.Natl.Acad.Sci.USA, 108, 2011
8GY6
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BU of 8gy6 by Molmil
Structure of SARS-CoV-2 RNA-dependent RNA polymerase with gossypol binding
分子名称: Gossypol, Non-structural protein 7, Non-structural protein 8, ...
著者Wang, W, Ren, M, Li, F.
登録日2022-09-21
公開日2023-11-01
実験手法ELECTRON MICROSCOPY
主引用文献Structure of SARS-CoV-2 RNA-dependent RNA polymerase with gossypol binding
To Be Published
4L67
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BU of 4l67 by Molmil
Crystal Structure of Catalytic Domain of PAK4
分子名称: Serine/threonine-protein kinase PAK 4
著者Wang, W, Song, J.
登録日2013-06-12
公開日2013-08-14
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献NMR binding and crystal structure reveal that intrinsically-unstructured regulatory domain auto-inhibits PAK4 by a mechanism different for that of PAK1
Biochem.Biophys.Res.Commun., 438, 2013
8XZG
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BU of 8xzg by Molmil
Cryo-EM structure of the [Pyr1]-apelin-13-bound human APLNR-Gi complex
分子名称: Apelin receptor, Apelin-13, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Wang, W, Ji, S, Zhang, Y.
登録日2024-01-21
公開日2024-03-27
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structure-based design of non-hypertrophic apelin receptor modulator.
Cell, 187, 2024
7XUR
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BU of 7xur by Molmil
The cryo-EM structure of human mini-SNAPc in complex with hU6-1 PSE
分子名称: DNA (35-MER), ZINC ION, snRNA-activating protein complex subunit 1, ...
著者Wang, W, Sun, J.F.
登録日2022-05-19
公開日2022-12-07
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.49 Å)
主引用文献Structural basis of human SNAPc recognizing proximal sequence element of snRNA promoter.
Nat Commun, 13, 2022
8GYN
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BU of 8gyn by Molmil
zebrafish TIPE1 strucutre in complex with PE
分子名称: Tumor necrosis factor alpha-induced protein 8-like protein 1, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate
著者Wang, W, Cao, S.J.
登録日2022-09-23
公開日2023-04-19
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.38 Å)
主引用文献Structural insight into TIPE1 functioning as a lipid transfer protein.
J.Biomol.Struct.Dyn., 41, 2023
7TNY
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BU of 7tny by Molmil
Cryo-EM structure of RIG-I in complex with p2dsRNA
分子名称: Antiviral innate immune response receptor RIG-I, ZINC ION, p2dsRNA
著者Wang, W, Pyle, A.M.
登録日2022-01-22
公開日2022-11-02
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands.
Mol.Cell, 82, 2022
7TNX
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BU of 7tnx by Molmil
Cryo-EM structure of RIG-I in complex with p3dsRNA
分子名称: Antiviral innate immune response receptor RIG-I, ZINC ION, p3dsRNAa, ...
著者Wang, W, Pyle, A.M.
登録日2022-01-22
公開日2022-11-02
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.54 Å)
主引用文献The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands.
Mol.Cell, 82, 2022
7TO2
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BU of 7to2 by Molmil
Cryo-EM structure of RIG-I bound to the internal sites of p3SLR30 (+ATP)
分子名称: ADENOSINE-5'-DIPHOSPHATE, Antiviral innate immune response receptor RIG-I, MAGNESIUM ION, ...
著者Wang, W, Pyle, A.M.
登録日2022-01-22
公開日2022-11-02
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands.
Mol.Cell, 82, 2022
7TO1
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BU of 7to1 by Molmil
Cryo-EM structure of RIG-I bound to the end of p3SLR30 (+ATP)
分子名称: Antiviral innate immune response receptor RIG-I, ZINC ION, p3SLR30
著者Wang, W, Pyle, A.M.
登録日2022-01-22
公開日2022-11-02
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.66 Å)
主引用文献The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands.
Mol.Cell, 82, 2022
7TO0
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BU of 7to0 by Molmil
Cryo-EM structure of RIG-I in complex with OHdsRNA
分子名称: Antiviral innate immune response receptor RIG-I, OHdsRNA, ZINC ION
著者Wang, W, Pyle, A.M.
登録日2022-01-22
公開日2022-11-02
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands.
Mol.Cell, 82, 2022
7TNZ
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BU of 7tnz by Molmil
Cryo-EM structure of RIG-I in complex with p1dsRNA
分子名称: Antiviral innate immune response receptor RIG-I, ZINC ION, p1dsRNA
著者Wang, W, Pyle, A.M.
登録日2022-01-22
公開日2022-11-02
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.54 Å)
主引用文献The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands.
Mol.Cell, 82, 2022
8K8T
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BU of 8k8t by Molmil
Structure of CUL3-RBX1-KLHL22 complex
分子名称: Cullin-3, Kelch-like protein 22
著者Wang, W, Ling, L, Dai, Z, Zuo, P, Yin, Y.
登録日2023-07-31
公開日2024-05-22
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献A conserved N-terminal motif of CUL3 contributes to assembly and E3 ligase activity of CRL3 KLHL22.
Nat Commun, 15, 2024
8K9I
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BU of 8k9i by Molmil
Structure of CUL3-RBX1-KLHL22 complex without CUL3 NA motif
分子名称: Cullin-3, E3 ubiquitin-protein ligase RBX1, N-terminally processed, ...
著者Wang, W, Ling, L, Dai, Z, Zuo, P, Yin, Y.
登録日2023-08-01
公開日2024-05-29
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献A conserved N-terminal motif of CUL3 contributes to assembly and E3 ligase activity of CRL3 KLHL22.
Nat Commun, 15, 2024
4FXW
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BU of 4fxw by Molmil
Structure of phosphorylated SF1 complex with U2AF65-UHM domain
分子名称: SULFATE ION, Splicing factor 1, Splicing factor U2AF 65 kDa subunit
著者Wang, W, Bauer, W.J, Wedekind, J.E, Kielkopf, C.L.
登録日2012-07-03
公開日2013-01-16
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Structure of Phosphorylated SF1 Bound to U2AF(65) in an Essential Splicing Factor Complex.
Structure, 21, 2013
2MBE
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BU of 2mbe by Molmil
Backbone 1H and 15N Chemical Shift Assignments for the first domain of FAT10
分子名称: Ubiquitin D
著者Wang, W, Lim, L, Qin, H.
登録日2013-07-30
公開日2014-08-27
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Disruption of FAT10-MAD2 binding inhibits tumor progression.
Proc.Natl.Acad.Sci.USA, 111, 2014
5WVM
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BU of 5wvm by Molmil
Crystal structure of baeS cocrystallized with 2 mM indole
分子名称: Maltose-binding periplasmic protein,Two-component system sensor kinase, SULFATE ION
著者Wang, W, Zhang, Y, Rang, T, Xu, D.
登録日2016-12-26
公開日2018-01-03
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of the sensor domain of BaeS from Serratia marcescens FS14
Proteins, 85, 2017
5WVN
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BU of 5wvn by Molmil
Crystal structure of MBS-BaeS fusion protein
分子名称: Maltose-binding periplasmic protein,Two-component system sensor kinase, SULFATE ION
著者Wang, W, Zhang, Y, Ran, T, Xu, D.
登録日2016-12-26
公開日2018-01-03
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of the sensor domain of BaeS from Serratia marcescens FS14
Proteins, 85, 2017
3TAR
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BU of 3tar by Molmil
Crystal Structure of Bacillus DNA Polymerase I Large Fragment Bound to Duplex DNA with Cytosine-Adenine Mismatch at (n-6) Position
分子名称: 5'-D(*GP*AP*CP*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3', 5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*GP*CP*AP*CP*GP*TP*C)-3', DNA polymerase I, ...
著者Wang, W, Beese, L.S.
登録日2011-08-04
公開日2011-10-19
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural evidence for the rare tautomer hypothesis of spontaneous mutagenesis.
Proc.Natl.Acad.Sci.USA, 108, 2011
3SSK
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BU of 3ssk by Molmil
Engineered high-affinity halide-binding protein derived from YFP: bromide complex
分子名称: BROMIDE ION, Green fluorescent protein
著者Wang, W, Grimley, J.S, Beese, L.S, Hellinga, H.W.
登録日2011-07-08
公開日2012-07-11
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.361 Å)
主引用文献Determination of engineered chloride-binding site structures in fluorescent proteins reveals principles of halide recognition
To be Published

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件を2024-07-24に公開中

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