7WT7
 
 | | SARS-CoV-2 Omicron variant spike in complex with Fab 9A8 (State 1) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Fab 9A8, ... | | Authors: | Wang, X, Wang, L. | | Deposit date: | 2022-02-04 | | Release date: | 2023-06-07 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | A broader neutralizing antibody against all the current VOCs and VOIs targets unique epitope of SARS-CoV-2 RBD.
Cell Discov, 8, 2022
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7WT8
 | | SARS-CoV-2 Omicron variant spike in complex with Fab 9A8 (State 2) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Fab 9A8, ... | | Authors: | Wang, X, Wang, L. | | Deposit date: | 2022-02-04 | | Release date: | 2023-06-07 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | A broader neutralizing antibody against all the current VOCs and VOIs targets unique epitope of SARS-CoV-2 RBD.
Cell Discov, 8, 2022
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7FEE
 | | Crystal structure of the allosteric modulator ZCZ011 binding to CP55940-bound cannabinoid receptor 1 | | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 2-[(1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]-5-(2-methyloctan-2-yl)phenol, 6-methyl-3-[(1S)-2-nitro-1-thiophen-2-yl-ethyl]-2-phenyl-1H-indole, ... | | Authors: | Wang, X, Zhao, C, Shao, Z. | | Deposit date: | 2021-07-19 | | Release date: | 2022-06-15 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Molecular mechanism of allosteric modulation for the cannabinoid receptor CB1.
Nat.Chem.Biol., 18, 2022
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7YBJ
 | | SARS-CoV-2 Mu variant spike(close state) | | Descriptor: | Spike glycoprotein | | Authors: | Wang, X, Fu, W. | | Deposit date: | 2022-06-29 | | Release date: | 2023-07-12 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (3.73 Å) | | Cite: | Structures of SARS-CoV-2 spike protein alert noteworthy sites for the potential approaching variants.
Virol Sin, 37, 2022
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7YBI
 | | SARS-CoV-2 Mu variant spike (open state) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Wang, X, Fu, W. | | Deposit date: | 2022-06-29 | | Release date: | 2023-07-12 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Structures of SARS-CoV-2 spike protein alert noteworthy sites for the potential approaching variants.
Virol Sin, 37, 2022
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7YBL
 | | SARS-CoV-2 B.1.620 variant spike (close state) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Wang, X, Fu, W. | | Deposit date: | 2022-06-29 | | Release date: | 2023-08-09 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structures of SARS-CoV-2 spike protein alert noteworthy sites for the potential approaching variants.
Virol Sin, 37, 2022
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7YBH
 | | SARS-CoV-2 lambda variant spike | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | | Authors: | Wang, X, Fu, W. | | Deposit date: | 2022-06-29 | | Release date: | 2023-08-09 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Structures of SARS-CoV-2 spike protein alert noteworthy sites for the potential approaching variants.
Virol Sin, 37, 2022
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7YBM
 | | SARS-CoV-2 C.1.2 variant spike (Close state) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Wang, X, Fu, W. | | Deposit date: | 2022-06-29 | | Release date: | 2023-08-09 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (3.45 Å) | | Cite: | Structures of SARS-CoV-2 spike protein alert noteworthy sites for the potential approaching variants.
Virol Sin, 37, 2022
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7YBK
 | | SARS-CoV-2 B.1.620 variant spike (open state) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Wang, X, Fu, W. | | Deposit date: | 2022-06-29 | | Release date: | 2023-09-06 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Structures of SARS-CoV-2 spike protein alert noteworthy sites for the potential approaching variants.
Virol Sin, 37, 2022
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7YBN
 | | SARS-CoV-2 C.1.2 variant spike (Open state) | | Descriptor: | Spike glycoprotein | | Authors: | Wang, X, Fu, W. | | Deposit date: | 2022-06-29 | | Release date: | 2023-11-29 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (3.82 Å) | | Cite: | Structures of SARS-CoV-2 spike protein alert noteworthy sites for the potential approaching variants.
Virol Sin, 37, 2022
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8HXK
 | | BANAL-20-236 S1 in complex with R. Affinis ACE2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, ... | | Authors: | Wang, X, Xu, G. | | Deposit date: | 2023-01-04 | | Release date: | 2024-01-10 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | The selective effect of fecal-oral transmission on the S proteins of bat SARS-CoV-2 related coronaviruses in favor of stability over infectivity
To Be Published
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8HXJ
 | | BANAL-20-52 Spike trimer | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | | Authors: | Wang, X, Xu, G. | | Deposit date: | 2023-01-04 | | Release date: | 2024-01-10 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | The selective effect of fecal-oral transmission on the S proteins of bat SARS-CoV-2 related coronaviruses in favor of stability over infectivity
To Be Published
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6KEA
 | | crystal structure of MBP-tagged REV7-IpaB complex | | Descriptor: | Maltose-binding periplasmic protein,LINKER,hREV7,LINKER,Invasin IpaB,hREV3 | | Authors: | Wang, X, Pernicone, N, Pertz, L, Hua, D.P, Zhang, T.Q, Listovsky, T, Xie, W. | | Deposit date: | 2019-07-04 | | Release date: | 2019-09-11 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | REV7 has a dynamic adaptor region to accommodate small GTPase RAN/ShigellaIpaB ligands, and its activity is regulated by the RanGTP/GDP switch.
J.Biol.Chem., 294, 2019
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6L77
 | | Crystal structure of MS5 from Brassica napus | | Descriptor: | MS5a | | Authors: | Wang, X, Guan, Z.Y, Yin, P. | | Deposit date: | 2019-10-31 | | Release date: | 2020-06-03 | | Last modified: | 2020-12-09 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural analysis of the meiosis-related protein MS5 reveals non-canonical papain enhancement by cystatin-like folds.
Febs Lett., 594, 2020
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6M15
 | | Cryo-EM structures of HKU2 spike glycoproteins | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | | Authors: | Wang, X, Yu, J, Qiao, S, Guo, R. | | Deposit date: | 2020-02-24 | | Release date: | 2020-05-27 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (2.38 Å) | | Cite: | Cryo-EM structures of HKU2 and SADS-CoV spike glycoproteins provide insights into coronavirus evolution.
Nat Commun, 11, 2020
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6M16
 | | Cryo-EM structures of SADS-CoV spike glycoproteins | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | | Authors: | Wang, X, Yu, J, Qiao, S, Guo, R. | | Deposit date: | 2020-02-24 | | Release date: | 2020-05-27 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (2.83 Å) | | Cite: | Cryo-EM structures of HKU2 and SADS-CoV spike glycoproteins provide insights into coronavirus evolution.
Nat Commun, 11, 2020
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7D1L
 | | complex structure of two RRM domains | | Descriptor: | Embryonic developmental protein tofu-6, Uncharacterized protein | | Authors: | Wang, X, Liao, S, Xu, C. | | Deposit date: | 2020-09-14 | | Release date: | 2021-08-25 | | Last modified: | 2021-10-06 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Molecular basis for PICS-mediated piRNA biogenesis and cell division.
Nat Commun, 12, 2021
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7D2Y
 | | complex of two RRM domains | | Descriptor: | Embryonic developmental protein tofu-6, RRM2, SULFATE ION | | Authors: | Wang, X, Liao, S, Xu, C. | | Deposit date: | 2020-09-17 | | Release date: | 2021-08-25 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.68 Å) | | Cite: | Molecular basis for PICS-mediated piRNA biogenesis and cell division.
Nat Commun, 12, 2021
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7EJS
 | | Structure of ERH-2 bound to PICS-1 | | Descriptor: | Enhancer of rudimentary homolog 2,Protein pid-3 | | Authors: | Wang, X, Xu, C. | | Deposit date: | 2021-04-02 | | Release date: | 2021-08-25 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.387 Å) | | Cite: | Molecular basis for PICS-mediated piRNA biogenesis and cell division.
Nat Commun, 12, 2021
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7EJO
 | | Structure of ERH-2 bound to TOST-1 | | Descriptor: | Enhancer of rudimentary homolog 2, Enhancer of rudimentary homolog 2,Protein tost-1 | | Authors: | Wang, X, Xu, C. | | Deposit date: | 2021-04-02 | | Release date: | 2021-08-25 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.191 Å) | | Cite: | Molecular basis for PICS-mediated piRNA biogenesis and cell division.
Nat Commun, 12, 2021
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6NUC
 | | Structure of Calcineurin in complex with NHE1 peptide | | Descriptor: | CALCIUM ION, Calcineurin subunit B type 1, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Wang, X, Page, R, Peti, W. | | Deposit date: | 2019-01-31 | | Release date: | 2019-07-03 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Molecular basis for the binding and selective dephosphorylation of Na+/H+exchanger 1 by calcineurin.
Nat Commun, 10, 2019
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7Y96
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7Y9B
 | | Crystal structure of the membrane (M) protein of a SARS-COV-2-related coronavirus | | Descriptor: | 3,6,9,12,15-PENTAOXATRICOSAN-1-OL, Membrane protein | | Authors: | Wang, X, Sun, Z, Zhou, X. | | Deposit date: | 2022-06-24 | | Release date: | 2022-08-17 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.214 Å) | | Cite: | Crystal structure of the membrane (M) protein from a bat betacoronavirus.
Pnas Nexus, 2, 2023
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7CYG
 | | Crystal structure of a cysteine-pair mutant (Y113C-P190C) of a bacterial bile acid transporter before disulfide bond formation | | Descriptor: | Transporter, sodium/bile acid symporter family | | Authors: | Wang, X, Lyu, Y, Ji, Y, Sun, Z, Zhou, X. | | Deposit date: | 2020-09-03 | | Release date: | 2021-01-13 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.198 Å) | | Cite: | An engineered disulfide bridge traps and validates an outward-facing conformation in a bile acid transporter.
Acta Crystallogr D Struct Biol, 77, 2021
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7CYK
 | | Crystal structure of a second cysteine-pair mutant (V110C-I197C) of a bacterial bile acid transporter before disulfide bond formation | | Descriptor: | MERCURY (II) ION, Transporter, sodium/bile acid symporter family | | Authors: | Wang, X, Lyu, Y, Ji, Y, Sun, Z, Zhou, X. | | Deposit date: | 2020-09-03 | | Release date: | 2021-01-13 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.785 Å) | | Cite: | An engineered disulfide bridge traps and validates an outward-facing conformation in a bile acid transporter.
Acta Crystallogr D Struct Biol, 77, 2021
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