7YBN

SARS-CoV-2 C.1.2 variant spike (Open state)

Summary for 7YBN

Entry DOI	10.2210/pdb7ybn/pdb
EMDB information	33727
Descriptor	Spike glycoprotein (1 entity in total)
Functional Keywords	sars-cov-2, lambda, spike, viral protein
Biological source	Severe acute respiratory syndrome coronavirus 2
Total number of polymer chains	3
Total formula weight	423517.31
Authors	Wang, X.,Fu, W. (deposition date: 2022-06-29, release date: 2023-11-29, Last modification date: 2024-11-13)
Primary citation	Xing, X.,Wang, L.,Cui, Z.,Fu, W.,Zheng, T.,Qin, L.,Ge, P.,Qian, A.,Wang, N.,Yuan, S. Structures of SARS-CoV-2 spike protein alert noteworthy sites for the potential approaching variants. Virol Sin, 37:938-941, 2022 Cited by PubMed Abstract: • Deletion of residues 156–157 warps the neighboring beta-sheet and leads NTD and RBD to shift. • T859N stabilizes the packing of the 630 loop motif to make RBD standing transition more difficult. • The overall structures of the closed state S complex from different variants resemble each other. • Mutations in FPPR may affect the overall structure of the trimeric spike protein. PubMed: 36368512 DOI: 10.1016/j.virs.2022.11.003 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.82 Å)

Structure validation