4YKD
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3NI2
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![BU of 3ni2 by Molmil](/molmil-images/mine/3ni2) | Crystal structures and enzymatic mechanisms of a Populus tomentosa 4-coumarate:CoA ligase | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 4-coumarate:CoA ligase, 5'-O-{(S)-hydroxy[3-(4-hydroxyphenyl)propoxy]phosphoryl}adenosine | Authors: | Hu, Y, Yin, L, Gai, Y, Wang, X.X, Wang, D.C. | Deposit date: | 2010-06-14 | Release date: | 2010-09-08 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structures of a Populus tomentosa 4-coumarate:CoA ligase shed light on its enzymatic mechanisms Plant Cell, 22, 2010
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3H98
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![BU of 3h98 by Molmil](/molmil-images/mine/3h98) | Crystal structure of HCV NS5b 1b with (1,1-dioxo-2H-[1,2,4]benzothiadiazin-3-yl) azolo[1,5-a]pyrimidine derivative | Descriptor: | GLYCEROL, N-{3-[5-hydroxy-8-(3-methylbutyl)-7-oxo-7,8-dihydroimidazo[1,2-a]pyrimidin-6-yl]-1,1-dioxido-4H-1,2,4-benzothiadiazin-7-yl}methanesulfonamide, RNA-directed RNA polymerase | Authors: | Wang, G, Lei, H, Wang, X, Das, D, Mackinnon, C, Montalbetti, C.A.G, Mears, R, Gai, X, Bailey, S, Ruhrmund, D, Hooi, L, Misialek, S, Rajagopalan, R, Cheng, R.K.Y, Barker, J.L, Felicetti, B, Stoycheva, A, Buckman, B, Kossen, K, Seiwert, S, Beigelmana, L. | Deposit date: | 2009-04-30 | Release date: | 2009-10-13 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | HCV NS5B polymerase inhibitors 2: Synthesis and in vitro activity of (1,1-dioxo-2H-[1,2,4]benzothiadiazin-3-yl) azolo[1,5-a]pyridine and azolo[1,5-a]pyrimidine derivatives. Bioorg.Med.Chem.Lett., 19, 2009
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4QBE
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![BU of 4qbe by Molmil](/molmil-images/mine/4qbe) | The second sphere residue T263 is important for function and activity of PTP1B through modulating WPD loop | Descriptor: | Tyrosine-protein phosphatase non-receptor type 1 | Authors: | Xiao, P, Wang, X, Wang, H.M, Fu, X.L, Cui, F.A, Yu, X, Bi, W.X. | Deposit date: | 2014-05-08 | Release date: | 2014-12-24 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.292 Å) | Cite: | The second-sphere residue T263 is important for the function and catalytic activity of PTP1B via interaction with the WPD-loop Int.J.Biochem.Cell Biol., 57C, 2014
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4QBW
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![BU of 4qbw by Molmil](/molmil-images/mine/4qbw) | The second sphere residue T263 is important for function and activity of PTP1B through modulating WPD loop | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein phosphatase non-receptor type 1 | Authors: | Xiao, P, Wang, X, Wang, H.M, Fu, X.L, Cui, F.A, Yu, X, Bi, W.X, Sun, J.P. | Deposit date: | 2014-05-08 | Release date: | 2015-02-11 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.912 Å) | Cite: | The second-sphere residue T263 is important for the function and catalytic activity of PTP1B via interaction with the WPD-loop Int.J.Biochem.Cell Biol., 57, 2014
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4QAP
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![BU of 4qap by Molmil](/molmil-images/mine/4qap) | The second sphere residue T263 is important for function and activity of PTP1B through modulating WPD loop | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein phosphatase non-receptor type 1 | Authors: | Xiao, P, Wang, X, Wang, H.M, Fu, X.L, Cui, F.A, Yu, X, Bi, W.X, Sun, J.P. | Deposit date: | 2014-05-05 | Release date: | 2015-02-11 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.903 Å) | Cite: | The second-sphere residue T263 is important for the function and catalytic activity of PTP1B via interaction with the WPD-loop Int.J.Biochem.Cell Biol., 57, 2014
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4QAH
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![BU of 4qah by Molmil](/molmil-images/mine/4qah) | The second sphere residue T263 is important for function and activity of PTP1B through modulating WPD loop | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein phosphatase non-receptor type 1 | Authors: | Xiao, P, Wang, X, Wang, H.M, Fu, X.L, Cui, F.A, Bi, W.X. | Deposit date: | 2014-05-05 | Release date: | 2014-12-24 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.403 Å) | Cite: | The second-sphere residue T263 is important for the function and catalytic activity of PTP1B via interaction with the WPD-loop Int.J.Biochem.Cell Biol., 57C, 2014
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5HQP
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![BU of 5hqp by Molmil](/molmil-images/mine/5hqp) | Crystal structure of the ERp44-peroxiredoxin 4 complex | Descriptor: | Endoplasmic reticulum resident protein 44, Peroxiredoxin-4 | Authors: | Yang, K, Li, D.F, Wang, X, Wang, C.C. | Deposit date: | 2016-01-22 | Release date: | 2016-10-12 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal Structure of the ERp44-Peroxiredoxin 4 Complex Reveals the Molecular Mechanisms of Thiol-Mediated Protein Retention. Structure, 24, 2016
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3NR2
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![BU of 3nr2 by Molmil](/molmil-images/mine/3nr2) | Crystal structure of Caspase-6 zymogen | Descriptor: | Caspase-6 | Authors: | Su, X.-D, Wang, X.-J, Liu, X, Mi, W, Wang, K.-T. | Deposit date: | 2010-06-30 | Release date: | 2010-10-27 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structures of human caspase 6 reveal a new mechanism for intramolecular cleavage self-activation Embo Rep., 11, 2010
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7XGL
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![BU of 7xgl by Molmil](/molmil-images/mine/7xgl) | Quinolinate Phosphoribosyl Transferase (QAPRTase) from Streptomyces pyridomyceticus NRRL B-2517 in Apo form | Descriptor: | CHLORIDE ION, GLYCEROL, Quinolinate Phosphoribosyl Transferase, ... | Authors: | Zhou, Z, Yang, X, Huang, T, Wang, X, Liang, R, Zheng, J, Dai, S, Lin, S, Deng, Z. | Deposit date: | 2022-04-05 | Release date: | 2023-03-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | Bifunctional NadC Homologue PyrZ Catalyzes Nicotinic Acid Formation in Pyridomycin Biosynthesis. Acs Chem.Biol., 18, 2023
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7XGM
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![BU of 7xgm by Molmil](/molmil-images/mine/7xgm) | Quinolinate Phosphoribosyl Transferase (QAPRTase) from Streptomyces pyridomyceticus NRRL B-2517 in complex with Quinolinic Acid (QA) | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, QUINOLINIC ACID, ... | Authors: | Zhou, Z, Yang, X, Huang, T, Wang, X, Liang, R, Zheng, J, Dai, S, Lin, S, Deng, Z. | Deposit date: | 2022-04-05 | Release date: | 2023-03-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Bifunctional NadC Homologue PyrZ Catalyzes Nicotinic Acid Formation in Pyridomycin Biosynthesis. Acs Chem.Biol., 18, 2023
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7XGN
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![BU of 7xgn by Molmil](/molmil-images/mine/7xgn) | Quinolinate Phosphoribosyl Transferase (QAPRTase) from Streptomyces pyridomyceticus NRRL B-2517 in complex with Nicotinic Acid (NA) | Descriptor: | CHLORIDE ION, NICOTINIC ACID, Quinolinate Phosphoribosyl Transferase, ... | Authors: | Zhou, Z, Yang, X, Huang, T, Wang, X, Liang, R, Zheng, J, Dai, S, Lin, S, Deng, Z. | Deposit date: | 2022-04-05 | Release date: | 2023-03-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Bifunctional NadC Homologue PyrZ Catalyzes Nicotinic Acid Formation in Pyridomycin Biosynthesis. Acs Chem.Biol., 18, 2023
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7XYO
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![BU of 7xyo by Molmil](/molmil-images/mine/7xyo) | Crystal Structure of a M61 aminopeptidase family member from Myxococcus fulvus | Descriptor: | Aminopeptidase M61, HEXAETHYLENE GLYCOL, TETRAETHYLENE GLYCOL, ... | Authors: | Chen, X, Wang, X, Huo, L, Wu, D. | Deposit date: | 2022-06-02 | Release date: | 2023-06-07 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Discovery and Characterization of a Myxobacterial Lanthipeptide with Unique Biosynthetic Features and Anti-inflammatory Activity. J.Am.Chem.Soc., 145, 2023
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6A67
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![BU of 6a67 by Molmil](/molmil-images/mine/6a67) | Crystal structure of influenza A virus H5 hemagglutinin globular head in complex with the Fab of antibody FLD21.140 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, FLD21.140 Heavy Chain, FLD21.140 Light Chain, ... | Authors: | Wang, P, Zuo, Y, Sun, J, Zhang, L, Wang, X. | Deposit date: | 2018-06-26 | Release date: | 2018-08-29 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.33 Å) | Cite: | Complementary recognition of the receptor-binding site of highly pathogenic H5N1 influenza viruses by two human neutralizing antibodies. J. Biol. Chem., 293, 2018
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3J1E
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![BU of 3j1e by Molmil](/molmil-images/mine/3j1e) | Cryo-EM structure of 9-fold symmetric rATcpn-beta in apo state | Descriptor: | Chaperonin beta subunit | Authors: | Zhang, K, Wang, L, Liu, Y.X, Wang, X, Gao, B, Hu, Z.J, Ji, G, Chan, K.Y, Schulten, K, Dong, Z.Y, Sun, F. | Deposit date: | 2012-02-06 | Release date: | 2013-08-07 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (8.3 Å) | Cite: | Flexible interwoven termini determine the thermal stability of thermosomes. Protein Cell, 4, 2013
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3J1B
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![BU of 3j1b by Molmil](/molmil-images/mine/3j1b) | Cryo-EM structure of 8-fold symmetric rATcpn-alpha in apo state | Descriptor: | Chaperonin alpha subunit | Authors: | Zhang, K, Wang, L, Liu, Y.X, Wang, X, Gao, B, Hu, Z.J, Ji, G, Chan, K.Y, Schulten, K, Dong, Z.Y, Sun, F. | Deposit date: | 2012-02-06 | Release date: | 2013-08-07 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (4.9 Å) | Cite: | Flexible interwoven termini determine the thermal stability of thermosomes. Protein Cell, 4, 2013
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3J1C
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![BU of 3j1c by Molmil](/molmil-images/mine/3j1c) | Cryo-EM structure of 9-fold symmetric rATcpn-alpha in apo state | Descriptor: | Chaperonin alpha subunit | Authors: | Zhang, K, Wang, L, Liu, Y.X, Wang, X, Gao, B, Hu, Z.J, Ji, G, Chan, K.Y, Schulten, K, Dong, Z.Y, Sun, F. | Deposit date: | 2012-02-06 | Release date: | 2013-08-07 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (9.1 Å) | Cite: | Flexible interwoven termini determine the thermal stability of thermosomes. Protein Cell, 4, 2013
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5XBM
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![BU of 5xbm by Molmil](/molmil-images/mine/5xbm) | Structure of SCARB2-JL2 complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Lysosome membrane protein 2, ... | Authors: | Zhang, X, Yang, P, Wang, N, Zhang, J, Li, J, Guo, H, Yin, X, Rao, Z, Wang, X, Zhang, L. | Deposit date: | 2017-03-20 | Release date: | 2018-06-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.501 Å) | Cite: | The binding of a monoclonal antibody to the apical region of SCARB2 blocks EV71 infection. Protein Cell, 8, 2017
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5YFP
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![BU of 5yfp by Molmil](/molmil-images/mine/5yfp) | Cryo-EM Structure of the Exocyst Complex | Descriptor: | Exocyst complex component EXO70, Exocyst complex component EXO84, Exocyst complex component SEC10, ... | Authors: | Mei, K, Li, Y, Wang, S, Shao, G, Wang, J, Ding, Y, Luo, G, Yue, P, Liu, J.J, Wang, X, Dong, M.Q, Guo, W, Wang, H.W. | Deposit date: | 2017-09-21 | Release date: | 2018-01-31 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Cryo-EM structure of the exocyst complex Nat. Struct. Mol. Biol., 25, 2018
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3J1F
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![BU of 3j1f by Molmil](/molmil-images/mine/3j1f) | Cryo-EM structure of 9-fold symmetric rATcpn-beta in ATP-binding state | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Chaperonin beta subunit, MAGNESIUM ION | Authors: | Zhang, K, Wang, L, Liu, Y.X, Wang, X, Gao, B, Hu, Z.J, Ji, G, Chan, K.Y, Schulten, K, Dong, Z.Y, Sun, F. | Deposit date: | 2012-02-06 | Release date: | 2013-08-07 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (6.2 Å) | Cite: | Flexible interwoven termini determine the thermal stability of thermosomes. Protein Cell, 4, 2013
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5YWO
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![BU of 5ywo by Molmil](/molmil-images/mine/5ywo) | Structure of JEV-2F2 Fab complex | Descriptor: | 2F2 heavy chain, 2F2 light chain, JEV E protein, ... | Authors: | Qiu, X, Lei, Y.F, Yang, P, Gao, Q, Wang, N, Cao, L, Yuan, S, Wang, X, Xu, Z.K, Rao, Z. | Deposit date: | 2017-11-29 | Release date: | 2018-03-21 | Last modified: | 2018-09-12 | Method: | ELECTRON MICROSCOPY (4.7 Å) | Cite: | Structural basis for neutralization of Japanese encephalitis virus by two potent therapeutic antibodies Nat Microbiol, 3, 2018
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5YWF
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![BU of 5ywf by Molmil](/molmil-images/mine/5ywf) | Crystal structure of 2H4 Fab | Descriptor: | 2H4 heavy chain, 2H4 light chain | Authors: | Qiu, X, Lei, Y, Yang, P, Gao, Q, Wang, N, Cao, L, Wang, X, Xu, Z.K, Rao, Z. | Deposit date: | 2017-11-29 | Release date: | 2018-03-21 | Method: | X-RAY DIFFRACTION (2.206 Å) | Cite: | Structural basis for neutralization of Japanese encephalitis virus by two potent therapeutic antibodies Nat Microbiol, 3, 2018
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4KC3
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![BU of 4kc3 by Molmil](/molmil-images/mine/4kc3) | Cytokine/receptor binary complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-1 receptor-like 1, Interleukin-33 | Authors: | Liu, X, Wang, X.Q. | Deposit date: | 2013-04-24 | Release date: | 2013-08-28 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (3.2702 Å) | Cite: | Structural insights into the interaction of IL-33 with its receptors. Proc.Natl.Acad.Sci.USA, 110, 2013
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4ELQ
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![BU of 4elq by Molmil](/molmil-images/mine/4elq) | Ferric binding protein with carbonate | Descriptor: | CARBONATE ION, Iron ABC transporter, periplasmic iron-binding protein | Authors: | Wang, Q, Liu, X.Q, Wang, X.Q. | Deposit date: | 2012-04-11 | Release date: | 2013-04-17 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.893 Å) | Cite: | Crystal structure of ferric binding protein A To be Published
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5XMK
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![BU of 5xmk by Molmil](/molmil-images/mine/5xmk) | Cryo-EM structure of the ATP-bound Vps4 mutant-E233Q complex with Vta1 (masked) | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Vacuolar protein sorting-associated protein 4, Vacuolar protein sorting-associated protein VTA1 | Authors: | Sun, S, Li, L, Yang, F, Wang, X, Fan, F, Li, X, Wang, H, Sui, S. | Deposit date: | 2017-05-15 | Release date: | 2017-08-09 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4.18 Å) | Cite: | Cryo-EM structures of the ATP-bound Vps4(E233Q) hexamer and its complex with Vta1 at near-atomic resolution Nat Commun, 8, 2017
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