6SX4
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6SWZ
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3P26
| Crystal structure of S. cerevisiae Hbs1 protein (apo-form), a translational GTPase involved in RNA quality control pathways and interacting with Dom34/Pelota | 分子名称: | Elongation factor 1 alpha-like protein | 著者 | van den Elzen, A, Henri, J, Lazar, N, Gas, M.E, Durand, D, Lacroute, F, Nicaise, M, van Tilbeurgh, H, Sraphin, B, Graille, M, Paris-Sud Yeast Structural Genomics (YSG) | 登録日 | 2010-10-01 | 公開日 | 2010-11-17 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Dissection of Dom34-Hbs1 reveals independent functions in two RNA quality control pathways. Nat.Struct.Mol.Biol., 17, 2010
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3P27
| Crystal structure of S. cerevisiae Hbs1 protein (GDP-bound form), a translational GTPase involved in RNA quality control pathways and interacting with Dom34/Pelota | 分子名称: | Elongation factor 1 alpha-like protein, GUANOSINE-5'-DIPHOSPHATE | 著者 | van den Elzen, A, Henri, J, Lazar, N, Gas, M.E, Durand, D, Lacroute, F, Nicaise, M, van Tilbeurgh, H, Sraphin, B, Graille, M, Paris-Sud Yeast Structural Genomics (YSG) | 登録日 | 2010-10-01 | 公開日 | 2010-11-17 | 最終更新日 | 2012-03-14 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Dissection of Dom34-Hbs1 reveals independent functions in two RNA quality control pathways. Nat.Struct.Mol.Biol., 17, 2010
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4FZB
| Structure of thymidylate synthase ThyX complexed to a new inhibitor | 分子名称: | 2-hydroxy-3-(4-methoxybenzyl)naphthalene-1,4-dione, DIMETHYL SULFOXIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... | 著者 | Basta, T, Boum, Y, Briffotaux, J, Becker, H.F, Lamarre-Jouenne, I, Lambry, J.C, Skouloubris, S, Liebl, U, van Tilbeurgh, H, Graille, M, Myllylkallio, H. | 登録日 | 2012-07-06 | 公開日 | 2013-05-22 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | 主引用文献 | Mechanistic and structural basis for inhibition of thymidylate synthase ThyX. Open Biology, 2, 2012
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4XVP
| X-ray structure of bGFP-C / EGFP complex | 分子名称: | BGFP-C, Green fluorescent protein | 著者 | Chevrel, A, Urvoas, A, Li de la Sierra-Gallay, I, Van Tilbeurgh, H, Minard, P, Valerio-Lepiniec, M. | 登録日 | 2015-01-27 | 公開日 | 2015-08-19 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Specific GFP-binding artificial proteins ( alpha Rep): a new tool for in vitro to live cell applications. Biosci.Rep., 35, 2015
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4YDU
| Crystal structure of E. coli YgjD-YeaZ heterodimer in complex with ADP | 分子名称: | ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, FE (III) ION, ... | 著者 | Zhang, W, Collinet, B, Perrochia, L, Durand, D, Van Tilbeurgh, H. | 登録日 | 2015-02-23 | 公開日 | 2015-03-04 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | 主引用文献 | The ATP-mediated formation of the YgjD-YeaZ-YjeE complex is required for the biosynthesis of tRNA t6A in Escherichia coli. Nucleic Acids Res., 43, 2015
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4YFM
| Class A beta-lactamase from Mycobacterium abscessus | 分子名称: | ACETATE ION, Beta-lactamase, GLYCEROL | 著者 | Soroka, D, Li de la Sierra-Gallay, I, Dubee, V, van Tilbeurgh, H, Arthur, M. | 登録日 | 2015-02-25 | 公開日 | 2015-07-22 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Hydrolysis of Clavulanate by Mycobacterium tuberculosis beta-Lactamase BlaC Harboring a Canonical SDN Motif. Antimicrob.Agents Chemother., 59, 2015
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6Z81
| TsaBD bound to the inhibitor | 分子名称: | (2~{S},3~{R})-2-[2-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]ethanoylamino]-3-oxidanyl-butanoic acid, ACETATE ION, ADENOSINE MONOPHOSPHATE, ... | 著者 | Missoury, S, Van Tilbeurgh, H. | 登録日 | 2020-06-02 | 公開日 | 2021-02-10 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | Structure of a reaction intermediate mimic in t6A biosynthesis bound in the active site of the TsaBD heterodimer from Escherichia coli. Nucleic Acids Res., 49, 2021
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3DF6
| The thermo- and acido-stable ORF-99 from the archaeal virus AFV1 | 分子名称: | CALCIUM ION, ORF99 | 著者 | Goulet, A, Spinelli, S, Prangishvili, D, van Tilbeurgh, H, Cambillau, C, Campanacci, V. | 登録日 | 2008-06-11 | 公開日 | 2009-06-16 | 最終更新日 | 2021-11-10 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | The thermo- and acido-stable ORF-99 from the archaeal virus AFV1 Protein Sci., 18, 2009
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3DJW
| The thermo- and acido-stable ORF-99 from the archaeal virus AFV1 | 分子名称: | ORF99 | 著者 | Goulet, A, Spinelli, S, Prangishvili, D, van Tilbeurgh, H, Cambillau, C, Campanacci, V. | 登録日 | 2008-06-24 | 公開日 | 2009-06-16 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | The thermo- and acido-stable ORF-99 from the archaeal virus AFV1 Protein Sci., 18, 2009
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4II9
| Crystal structure of Weissella viridescens FemXVv non-ribosomal amino acid transferase in complex with a peptidyl-RNA conjugate | 分子名称: | 5-mer peptide, FemX, GLYCEROL, ... | 著者 | Li de la Sierra-Gallay, I, Fonvielle, M, van Tilbeurgh, H, Arthur, M, Etheve-Quelquejeu, M. | 登録日 | 2012-12-20 | 公開日 | 2013-07-03 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | 主引用文献 | The Structure of FemXWv in Complex with a Peptidyl-RNA Conjugate: Mechanism of Aminoacyl Transfer from Ala-tRNA(Ala) to Peptidoglycan Precursors Angew.Chem.Int.Ed.Engl., 52, 2013
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6F87
| Crystal structure of P. abyssi Sua5 complexed with L-threonine and PPi | 分子名称: | PYROPHOSPHATE 2-, THREONINE, Threonylcarbamoyl-AMP synthase | 著者 | Pichard-Kostuch, A, Zhang, W, Liger, D, Daugeron, M.C, Letoquart, J, Li de la Sierra-Gallay, I, Forterre, P, Collinet, B, van Tilbeurgh, H, Basta, T. | 登録日 | 2017-12-12 | 公開日 | 2018-04-25 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | 主引用文献 | Structure-function analysis of Sua5 protein reveals novel functional motifs required for the biosynthesis of the universal t6A tRNA modification. RNA, 24, 2018
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6F8Y
| Crystal structure of P. abyssi Sua5 complexed with L-threonine | 分子名称: | THREONINE, Threonylcarbamoyl-AMP synthase | 著者 | Pichard-Kostuch, A, Zhang, W, Liger, D, Daugeron, M.C, Letoquart, J, Li de la Sierra-Gallay, I, Forterre, P, Collinet, B, van Tilbeurgh, H, Basta, T. | 登録日 | 2017-12-13 | 公開日 | 2018-04-25 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.86 Å) | 主引用文献 | Structure-function analysis of Sua5 protein reveals novel functional motifs required for the biosynthesis of the universal t6A tRNA modification. RNA, 24, 2018
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6FJ1
| Structure of the Ldtfm-avibactam carbamoyl enzyme | 分子名称: | (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, 3,6,9,12,15-PENTAOXAHEPTADECANE, CHLORIDE ION, ... | 著者 | Li de la Sierra Gallay, I, Iannazzo, L, Compain, F, Fonvielle, M, van Tilbeurgh, H, Edoo, Z, Arthur, M, Etheve-Quelquejeu, M, Hugonnet, J. | 登録日 | 2018-01-19 | 公開日 | 2019-01-30 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | 主引用文献 | Synthesis of Avibactam Derivatives and Activity on beta-Lactamases and Peptidoglycan Biosynthesis Enzymes of Mycobacteria. Chemistry, 24, 2018
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4H18
| Three dimensional structure of corynomycoloyl tranferase C | 分子名称: | Cmt1, MAGNESIUM ION | 著者 | Huc, E, de Sousa D'Auria, C, Li de la Sierra-Gallay, I, Salmeron, C.H, van Tilbeurgh, H, Bayan, N, Houssin, C.H, Daffe, M, Tropis, M. | 登録日 | 2012-09-10 | 公開日 | 2013-09-25 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.755 Å) | 主引用文献 | Identification of a mycoloyl transferase selectively involved in o-acylation of polypeptides in corynebacteriales. J.Bacteriol., 195, 2013
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4HV0
| Structure and Function of AvtR, a Novel Transcriptional Regulator from a Hyperthermophilic Archaeal Lipothrixvirus | 分子名称: | AvtR | 著者 | Peixeiro, N, Keller, J, Collinet, B, Leulliot, N, Campanacci, V, Cortez, D, Cambillau, C, Nitta, K.R, Vincentelli, R, Forterre, P, Prangishvili, D, Sezonov, G, van Tilbeurgh, H. | 登録日 | 2012-11-05 | 公開日 | 2012-11-21 | 最終更新日 | 2012-12-26 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure and Function of AvtR, a Novel Transcriptional Regulator from a Hyperthermophilic Archaeal Lipothrixvirus. J.Virol., 87, 2013
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3Q87
| Structure of E. cuniculi Mtq2-Trm112 complex responible for the methylation of eRF1 translation termination factor | 分子名称: | N6 adenine specific DNA methylase, Putative uncharacterized protein ECU08_1170, S-ADENOSYLMETHIONINE, ... | 著者 | Liger, D, Mora, L, Lazar, N, Figaro, S, Henri, J, Scrima, N, Buckingham, R.H, van Tilbeurgh, H, Heurgue-Hamard, V, Graille, M. | 登録日 | 2011-01-06 | 公開日 | 2011-05-18 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.997 Å) | 主引用文献 | Mechanism of activation of methyltransferases involved in translation by the Trm112 'hub' protein Nucleic Acids Res., 2011
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4JW3
| Selection of specific protein binders for pre-defined targets from an optimized library of artificial helicoidal repeat proteins (alphaRep) | 分子名称: | Alpha-helical artificial proteins, Neocarzinostatin | 著者 | Guellouz, A, Valerio-Lepiniec, M, Urvoas, A, Chevrel, A, Graille, M, Fourati-Kammoun, Z, Desmadril, M, van Tilbeurgh, H, Minard, P. | 登録日 | 2013-03-27 | 公開日 | 2013-09-25 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Selection of Specific Protein Binders for Pre-Defined Targets from an Optimized Library of Artificial Helicoidal Repeat Proteins (alphaRep). Plos One, 8, 2013
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4JW2
| Selection of specific protein binders for pre-defined targets from an optimized library of artificial helicoidal repeat proteins (alphaRep) | 分子名称: | 1,2-ETHANEDIOL, A3 artificial protein, bA3-2: binder of A3 protein | 著者 | Guellouz, A, Valerio-Lepiniec, M, Urvoas, A, Chevrel, A, Graille, M, Fourati-Kammoun, Z, Desmadril, M, van Tilbeurgh, H, Minard, P. | 登録日 | 2013-03-27 | 公開日 | 2013-09-25 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Selection of Specific Protein Binders for Pre-Defined Targets from an Optimized Library of Artificial Helicoidal Repeat Proteins (alphaRep). Plos One, 8, 2013
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3QTN
| Structure of S. pombe nuclear import adaptor Nro1 (Space group P6522) | 分子名称: | Uncharacterized protein C4B3.07 | 著者 | Rispal, D, Henri, J, van Tilbeurgh, H, Graille, M, Seraphin, B. | 登録日 | 2011-02-23 | 公開日 | 2011-09-21 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.499 Å) | 主引用文献 | Structural and functional analysis of Nro1/Ett1: a protein involved in translation termination in S. cerevisiae and in O2-mediated gene control in S. pombe Rna, 17, 2011
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3QTM
| Structure of S. pombe nuclear import adaptor Nro1 (Space group P21) | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, SULFATE ION, ... | 著者 | Rispal, D, Henri, J, van Tilbeurgh, H, Graille, M, Seraphin, B. | 登録日 | 2011-02-23 | 公開日 | 2011-09-21 | 最終更新日 | 2018-01-03 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Structural and functional analysis of Nro1/Ett1: a protein involved in translation termination in S. cerevisiae and in O2-mediated gene control in S. pombe Rna, 17, 2011
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2VUG
| The structure of an archaeal homodimeric RNA ligase | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, PAB1020, ... | 著者 | Brooks, M.A, Meslet-Cladiere, L, Graille, M, Kuhn, J, Blondeau, K, Myllykallio, H, van Tilbeurgh, H. | 登録日 | 2008-05-26 | 公開日 | 2008-06-03 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | The structure of an archaeal homodimeric ligase which has RNA circularization activity. Protein Sci., 17, 2008
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2XAU
| Crystal structure of the Prp43p DEAH-box RNA helicase in complex with ADP | 分子名称: | ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ... | 著者 | Walbott, H, Mouffok, S, Capeyrou, R, Lebaron, S, van Tilbeurgh, H, Henry, Y, Leulliot, N. | 登録日 | 2010-03-31 | 公開日 | 2010-06-09 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Prp43P Contains a Processive Helicase Structural Architecture with a Specific Regulatory Domain. Embo J., 29, 2010
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4CBV
| X-ray structure of full-length ComE from Streptococcus pneumoniae. | 分子名称: | COME | 著者 | Boudes, M, Durand, D, Graille, M, van Tilbeurgh, H, Quevillon-Cheruel, S. | 登録日 | 2013-10-16 | 公開日 | 2014-02-12 | 最終更新日 | 2014-05-14 | 実験手法 | X-RAY DIFFRACTION (3.39 Å) | 主引用文献 | Structural Insights Into the Dimerization of the Response Regulator Come from Streptococcus Pneumoniae. Nucleic Acids Res., 42, 2014
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