7PCV
 
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7POF
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2WJV
 | | Crystal structure of the complex between human nonsense mediated decay factors UPF1 and UPF2 | | Descriptor: | REGULATOR OF NONSENSE TRANSCRIPTS 1, REGULATOR OF NONSENSE TRANSCRIPTS 2, SULFATE ION, ... | | Authors: | Clerici, M, Mourao, A, Gutsche, I, Gehring, N.H, Hentze, M.W, Kulozik, A, Kadlec, J, Sattler, M, Cusack, S. | | Deposit date: | 2009-06-01 | | Release date: | 2009-07-07 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | Unusual Bipartite Mode of Interaction between the Nonsense-Mediated Decay Factors, Upf1 and Upf2.
Embo J., 28, 2009
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2WJY
 | | Crystal structure of the complex between human nonsense mediated decay factors UPF1 and UPF2 Orthorhombic form | | Descriptor: | REGULATOR OF NONSENSE TRANSCRIPTS 1, SULFATE ION, ZINC ION | | Authors: | Clerici, M, Mourao, A, Gutsche, I, Gehring, N.H, Hentze, M.W, Kulozik, A, Kadlec, J, Sattler, M, Cusack, S. | | Deposit date: | 2009-06-01 | | Release date: | 2009-07-07 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Unusual Bipartite Mode of Interaction between the Nonsense-Mediated Decay Factors, Upf1 and Upf2.
Embo J., 28, 2009
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2W84
 | | Structure of Pex14 in complex with Pex5 | | Descriptor: | PEROXISOMAL MEMBRANE PROTEIN PEX14, PEROXISOMAL TARGETING SIGNAL 1 RECEPTOR | | Authors: | Neufeld, C, Filipp, F.V, Simon, B, Neuhaus, A, Schueller, N, David, C, Kooshapur, H, Madl, T, Erdmann, R, Schliebs, W, Wilmanns, M, Sattler, M. | | Deposit date: | 2009-01-09 | | Release date: | 2009-02-17 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structural basis for competitive interactions of Pex14 with the import receptors Pex5 and Pex19.
EMBO J., 28, 2009
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2W85
 | | Structure of Pex14 in complex with Pex19 | | Descriptor: | PEROXIN-19, PEROXISOMAL MEMBRANE ANCHOR PROTEIN PEX14 | | Authors: | Neufeld, C, Filipp, F.V, Simon, B, Neuhaus, A, Schueller, N, David, C, Kooshapur, H, Madl, T, Erdmann, R, Schliebs, W, Wilmanns, M, Sattler, M. | | Deposit date: | 2009-01-09 | | Release date: | 2009-02-17 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structural Basis for Competitive Interactions of Pex14 with the Import Receptors Pex5 and Pex19.
Embo J., 28, 2009
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2C5Z
 | | Structure and CTD binding of the Set2 SRI domain | | Descriptor: | SET DOMAIN PROTEIN 2 | | Authors: | Vojnic, E, Simon, B, Strahl, B.D, Sattler, M, Cramer, P. | | Deposit date: | 2005-11-03 | | Release date: | 2005-11-14 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structure and carboxyl-terminal domain (CTD) binding of the Set2 SRI domain that couples histone H3 Lys36 methylation to transcription.
J. Biol. Chem., 281, 2006
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8QF0
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1O6W
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2XNF
 | | The Mediator Med25 activator interaction domain: Structure and cooperative binding of VP16 subdomains | | Descriptor: | MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 25 | | Authors: | Vojnic, E, Mourao, A, Seizl, M, Simon, B, Wenzeck, L, Lariviere, L, Baumli, S, Meisterernst, M, Sattler, M, Cramer, P. | | Deposit date: | 2010-08-02 | | Release date: | 2011-03-09 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structure and Vp16 Binding of the Mediator Med25 Activator Interaction Domain.
Nat.Struct.Mol.Biol., 18, 2011
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6GQE
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2B9Z
 | | Solution structure of FHV B2, a viral suppressor of RNAi | | Descriptor: | B2 protein | | Authors: | Lingel, A, Simon, B, Izaurralde, E, Sattler, M. | | Deposit date: | 2005-10-13 | | Release date: | 2005-11-29 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | The structure of the flock house virus B2 protein, a viral suppressor of RNA interference, shows a novel mode of double-stranded RNA recognition.
Embo Rep., 6, 2005
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6SPT
 | | High resolution crystal structure of N-terminal domain of PEX14 from Trypanosoma brucei in complex with the fist compound with sub-micromolar trypanocidal activity | | Descriptor: | 5-[(4-methoxynaphthalen-1-yl)methyl]-1-[2-[(2-methyl-1-oxidanyl-propan-2-yl)amino]ethyl]-~{N}-(naphthalen-1-ylmethyl)-6,7-dihydro-4~{H}-pyrazolo[4,3-c]pyridine-3-carboxamide, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... | | Authors: | Napolitano, V, Dawidowski, M, Kalel, V.C, Fino, R, Emmanouilidis, L, Lenhart, D, Ostertag, M, Kaiser, M, Kolonko, M, Schilebs, W, Maser, P, Tetko, I, Hadian, K, Plettenburg, O, Erdmann, R, Sattler, M, Popowicz, G.M, Dubin, G. | | Deposit date: | 2019-09-02 | | Release date: | 2020-01-01 | | Last modified: | 2020-02-05 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | Structure-Activity Relationship in Pyrazolo[4,3-c]pyridines, First Inhibitors of PEX14-PEX5 Protein-Protein Interaction with Trypanocidal Activity.
J.Med.Chem., 63, 2020
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1XX0
 | | Structure of the C-terminal PH domain of human pleckstrin | | Descriptor: | Pleckstrin | | Authors: | Edlich, C, Stier, G, Simon, B, Sattler, M, Muhle-Goll, C. | | Deposit date: | 2004-11-03 | | Release date: | 2005-05-03 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Structure and phosphatidylinositol-(3,4)-bisphosphate binding of the C-terminal PH domain of human pleckstrin
STRUCTURE, 13, 2005
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2Y95
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4JVU
 | | IgM C2-domain from mouse | | Descriptor: | Ig mu chain C region membrane-bound form | | Authors: | Mueller, R, Graewert, A.M, Kern, T, Madl, T, Peschek, J, Sattler, M, Groll, M, Buchner, J. | | Deposit date: | 2013-03-26 | | Release date: | 2013-06-12 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | High-resolution structures of the IgM Fc domains reveal principles of its hexamer formation.
Proc.Natl.Acad.Sci.USA, 110, 2013
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4JVW
 | | IgM C4-domain from mouse | | Descriptor: | Ig mu chain C region secreted form | | Authors: | Mueller, R, Graewert, A.M, Kern, T, Madl, T, Peschek, J, Sattler, M, Groll, M, Buchner, J. | | Deposit date: | 2013-03-26 | | Release date: | 2013-06-12 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | High-resolution structures of the IgM Fc domains reveal principles of its hexamer formation.
Proc.Natl.Acad.Sci.USA, 110, 2013
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4QI2
 | | X-ray structure of the ROQ domain from murine Roquin-1 in complex with a 23-mer Tnf-CDE RNA | | Descriptor: | RNA (5'-R(*AP*CP*AP*UP*GP*UP*UP*UP*UP*CP*UP*GP*UP*GP*AP*AP*AP*AP*CP*GP*GP*AP*G)-3'), Roquin-1 | | Authors: | Janowski, R, Schlundt, A, Sattler, M, Niessing, D. | | Deposit date: | 2014-05-30 | | Release date: | 2014-07-16 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural basis for RNA recognition in roquin-mediated post-transcriptional gene regulation.
Nat.Struct.Mol.Biol., 21, 2014
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5NPA
 | | Solution structure of Drosophila melanogaster Loquacious dsRBD2 | | Descriptor: | Loquacious | | Authors: | Tants, J.-N, Fesser, S, Kern, T, Stehle, R, Geerlof, A, Wunderlich, C, Boettcher, R, Kunzelmann, S, Lange, O, Kreutz, C, Foerstemann, K, Sattler, M. | | Deposit date: | 2017-04-16 | | Release date: | 2017-10-04 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Molecular basis for asymmetry sensing of siRNAs by the Drosophila Loqs-PD/Dcr-2 complex in RNA interference.
Nucleic Acids Res., 45, 2017
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5NPG
 | | Solution structure of Drosophila melanogaster Loquacious dsRBD1 | | Descriptor: | Loquacious, isoform F | | Authors: | Tants, J.-N, Fesser, S, Kern, T, Stehle, R, Geerlof, A, Wunderlich, C, Hartlmuller, C, Boettcher, R, Kunzelmann, S, Lange, O, Kreutz, C, Foerstemann, K, Sattler, M. | | Deposit date: | 2017-04-16 | | Release date: | 2017-10-04 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Molecular basis for asymmetry sensing of siRNAs by the Drosophila Loqs-PD/Dcr-2 complex in RNA interference.
Nucleic Acids Res., 45, 2017
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4AKA
 | | IPSE alpha-1, an IgE-binding crystallin | | Descriptor: | IL-4-INDUCING PROTEIN | | Authors: | Meyer, N.H, Mayerhofer, H, Tripsianes, K, Barths, D, Blindow, S, Bade, S, Madl, T, Frey, A, Haas, H, Mueller-Dieckmann, J, Sattler, M, Scharmm, G. | | Deposit date: | 2012-02-22 | | Release date: | 2013-03-13 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | A Crystallin Fold in the Interleukin-4-Inducing Principle of Schistosoma Mansoni Eggs (Ipse/Alpha-1) Mediates Ige Binding for Antigen-Independent Basophil Activation
J.Biol.Chem., 290, 2015
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1ZZJ
 | | Structure of the third KH domain of hnRNP K in complex with 15-mer ssDNA | | Descriptor: | 5'-D(*TP*TP*CP*CP*CP*CP*TP*CP*CP*CP*CP*AP*TP*TP*T)-3', Heterogeneous nuclear ribonucleoprotein K | | Authors: | Backe, P.H, Messias, A.C, Ravelli, R.B, Sattler, M, Cusack, S. | | Deposit date: | 2005-06-14 | | Release date: | 2005-08-09 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | X-Ray Crystallographic and NMR Studies of the Third KH Domain of hnRNP K in Complex with Single-Stranded Nucleic Acids
STRUCTURE, 13, 2005
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1XWH
 | | NMR structure of the first phd finger of autoimmune regulator protein (AIRE1): insights into apeced | | Descriptor: | Autoimmune regulator, ZINC ION | | Authors: | Bottomley, M.J, Stier, G, Krasotkina, J, Legube, G, Simon, B, Akhtar, A, Sattler, M, Musco, G. | | Deposit date: | 2004-11-01 | | Release date: | 2005-01-25 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | NMR structure of the first PHD finger of autoimmune regulator protein (AIRE1). Insights into autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) disease
J.Biol.Chem., 280, 2005
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1ZZK
 | | Crystal Structure of the third KH domain of hnRNP K at 0.95A resolution | | Descriptor: | Heterogeneous nuclear ribonucleoprotein K | | Authors: | Backe, P.H, Messias, A.C, Ravelli, R.B, Sattler, M, Cusack, S. | | Deposit date: | 2005-06-14 | | Release date: | 2005-08-09 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (0.95 Å) | | Cite: | X-Ray Crystallographic and NMR Studies of the Third KH Domain of hnRNP K in Complex with Single-Stranded Nucleic Acids
STRUCTURE, 13, 2005
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1ZZI
 | | Crystal Structure Analysis of the third KH domain of hnRNP K in complex with ssDNA | | Descriptor: | 5'-D(*CP*TP*CP*CP*CP*C)-3', Heterogeneous nuclear ribonucleoprotein K | | Authors: | Backe, P.H, Messias, A.C, Ravelli, R.B, Sattler, M, Cusack, S. | | Deposit date: | 2005-06-14 | | Release date: | 2005-08-09 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | X-Ray Crystallographic and NMR Studies of the Third KH Domain of hnRNP K in Complex with Single-Stranded Nucleic Acids
STRUCTURE, 13, 2005
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