8HDF
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![BU of 8hdf by Molmil](/molmil-images/mine/8hdf) | Full length crystal structure of mycobacterium tuberculosis FadD23 in complex with ANP and PLM | 分子名称: | Long-chain-fatty-acid--AMP ligase FadD23, PALMITIC ACID, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | 著者 | Yan, M.R, Liu, X, Zhang, W, Rao, Z.H. | 登録日 | 2022-11-04 | 公開日 | 2023-02-15 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | 主引用文献 | The Key Roles of Mycobacterium tuberculosis FadD23 C-terminal Domain in Catalytic Mechanisms. Front Microbiol, 14, 2023
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8HD4
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![BU of 8hd4 by Molmil](/molmil-images/mine/8hd4) | Full-length crystal structure of mycobacterium tuberculosis FadD23 in complex with AMPC16 | 分子名称: | Long-chain-fatty-acid--AMP ligase FadD23, palmitoyl adenylate | 著者 | Yan, M.R, Liu, X, Zhang, W, Rao, Z.H. | 登録日 | 2022-11-03 | 公開日 | 2023-02-15 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | 主引用文献 | The Key Roles of Mycobacterium tuberculosis FadD23 C-terminal Domain in Catalytic Mechanisms. Front Microbiol, 14, 2023
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6EG8
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![BU of 6eg8 by Molmil](/molmil-images/mine/6eg8) | Structure of the GDP-bound Gs heterotrimer | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Hilger, D, Liu, X, Aschauer, P, Kobilka, B.K. | 登録日 | 2018-08-19 | 公開日 | 2019-06-05 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural Insights into the Process of GPCR-G Protein Complex Formation. Cell, 177, 2019
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1FAW
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![BU of 1faw by Molmil](/molmil-images/mine/1faw) | GRAYLAG GOOSE HEMOGLOBIN (OXY FORM) | 分子名称: | HEMOGLOBIN (ALPHA SUBUNIT), HEMOGLOBIN (BETA SUBUNIT), OXYGEN MOLECULE, ... | 著者 | Liang, Y.-H, Liu, X.-Z, Liu, S.-H, Lu, G.-Y. | 登録日 | 2000-07-13 | 公開日 | 2001-12-05 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (3.09 Å) | 主引用文献 | The structure of greylag goose oxy haemoglobin: the roles of four mutations compared with bar-headed goose haemoglobin. Acta Crystallogr.,Sect.D, 57, 2001
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6LJ9
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![BU of 6lj9 by Molmil](/molmil-images/mine/6lj9) | |
6L31
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![BU of 6l31 by Molmil](/molmil-images/mine/6l31) | L1 protein of human papillomavirus 6 | 分子名称: | Major capsid protein L1 | 著者 | Li, S.W, Liu, X.L, Gu, Y. | 登録日 | 2019-10-07 | 公開日 | 2019-12-25 | 実験手法 | ELECTRON MICROSCOPY (4.18 Å) | 主引用文献 | Neutralization sites of human papillomavirus-6 relate to virus attachment and entry phase in viral infection. Emerg Microbes Infect, 8, 2019
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6LJB
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8X2L
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![BU of 8x2l by Molmil](/molmil-images/mine/8x2l) | |
9IJD
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![BU of 9ijd by Molmil](/molmil-images/mine/9ijd) | Carazolol-activated human beta3 adrenergic receptor | 分子名称: | (2S)-1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol, Beta-3 adrenergic receptor, Camelid antibody VHH fragment, ... | 著者 | Zheng, S, Zhang, S, Dai, S, Chen, K, Gao, K, Lin, B, Liu, X. | 登録日 | 2024-06-22 | 公開日 | 2024-08-21 | 実験手法 | ELECTRON MICROSCOPY (2.76 Å) | 主引用文献 | Molecular Mechanism of the beta 3AR Agonist Activity of a beta-Blocker. Chempluschem, 2024
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9IJE
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![BU of 9ije by Molmil](/molmil-images/mine/9ije) | Epinephrine-activated human beta3 adrenergic receptor | 分子名称: | Beta-3 adrenergic receptor, Camelid antibody VHH fragment, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Zheng, S, Zhang, S, Dai, S, Chen, K, Gao, K, Lin, B, Liu, X. | 登録日 | 2024-06-22 | 公開日 | 2024-08-21 | 実験手法 | ELECTRON MICROSCOPY (2.34 Å) | 主引用文献 | Molecular Mechanism of the beta 3AR Agonist Activity of a beta-Blocker. Chempluschem, 2024
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7QHE
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![BU of 7qhe by Molmil](/molmil-images/mine/7qhe) | Human Butyrylcholinesterase in complex with (S)-1-(4-((naphthalen-1-yl)carbamoyl)benzyl)-N-(3-((1,2,3,4-tetrahydroacridin-9-yl)amino)propyl)piperidine-3-carboxamide | 分子名称: | (3~{S})-1-[[4-(naphthalen-1-ylcarbamoyl)phenyl]methyl]-~{N}-[3-(1,2,3,4-tetrahydroacridin-9-ylamino)propyl]piperidine-3-carboxamide, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Brazzolotto, X, Jing, L, Zhan, P, Liu, X, Nachon, F. | 登録日 | 2021-12-12 | 公開日 | 2022-12-21 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | 主引用文献 | Rapid discovery and crystallography study of highly potent and selective butylcholinesterase inhibitors based on oxime-containing libraries and conformational restriction strategies. Bioorg.Chem., 134, 2023
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7QHD
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![BU of 7qhd by Molmil](/molmil-images/mine/7qhd) | Human Butyrylcholinesterase in complex with (S)-1-(4-((2-(1H-indol-3-yl)ethyl)carbamoyl)benzyl)-N-(3-((1,2,3,4-tetrahydroacridin-9-yl)amino)propyl)piperidine-3-carboxamide | 分子名称: | (3~{S})-1-[[4-[2-(1~{H}-indol-3-yl)ethylcarbamoyl]phenyl]methyl]-~{N}-[3-(1,2,3,4-tetrahydroacridin-9-ylamino)propyl]piperidine-3-carboxamide, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Brazzolotto, X, Jing, L, Zhan, P, Liu, X, Nachon, F. | 登録日 | 2021-12-12 | 公開日 | 2022-12-21 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | Rapid discovery and crystallography study of highly potent and selective butylcholinesterase inhibitors based on oxime-containing libraries and conformational restriction strategies. Bioorg.Chem., 134, 2023
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6M0K
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![BU of 6m0k by Molmil](/molmil-images/mine/6m0k) | The crystal structure of COVID-19 main protease in complex with an inhibitor 11b | 分子名称: | 3C-like proteinase, DIMETHYL SULFOXIDE, ~{N}-[(2~{S})-3-(3-fluorophenyl)-1-oxidanylidene-1-[[(2~{S})-1-oxidanylidene-3-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]amino]propan-2-yl]-1~{H}-indole-2-carboxamide | 著者 | Zhang, B, Zhao, Y, Jin, Z, Liu, X, Yang, H, Liu, H, Rao, Z, Jiang, H. | 登録日 | 2020-02-22 | 公開日 | 2020-04-29 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.504 Å) | 主引用文献 | Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease. Science, 368, 2020
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6LZE
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![BU of 6lze by Molmil](/molmil-images/mine/6lze) | The crystal structure of COVID-19 main protease in complex with an inhibitor 11a | 分子名称: | 3C-like proteinase, DIMETHYL SULFOXIDE, ~{N}-[(2~{S})-3-cyclohexyl-1-oxidanylidene-1-[[(2~{S})-1-oxidanylidene-3-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]amino]propan-2-yl]-1~{H}-indole-2-carboxamide | 著者 | Zhang, B, Zhang, Y, Jing, Z, Liu, X, Yang, H, Liu, H, Rao, Z, Jiang, H. | 登録日 | 2020-02-19 | 公開日 | 2020-04-29 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.505 Å) | 主引用文献 | Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease. Science, 368, 2020
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1BIO
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![BU of 1bio by Molmil](/molmil-images/mine/1bio) | HUMAN COMPLEMENT FACTOR D IN COMPLEX WITH ISATOIC ANHYDRIDE INHIBITOR | 分子名称: | COMPLEMENT FACTOR D, GLYCEROL, ISATOIC ANHYDRIDE | 著者 | Jing, H, Babu, Y.S, Moore, D, Kilpatrick, J.M, Liu, X.-Y, Volanakis, J.E, Narayana, S.V.L. | 登録日 | 1998-06-18 | 公開日 | 1999-06-22 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structures of native and complexed complement factor D: implications of the atypical His57 conformation and self-inhibitory loop in the regulation of specific serine protease activity. J.Mol.Biol., 282, 1998
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3JCU
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![BU of 3jcu by Molmil](/molmil-images/mine/3jcu) | Cryo-EM structure of spinach PSII-LHCII supercomplex at 3.2 Angstrom resolution | 分子名称: | (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, ... | 著者 | Wei, X.P, Zhang, X.Z, Su, X.D, Cao, P, Liu, X.Y, Li, M, Chang, W.R, Liu, Z.F. | 登録日 | 2016-03-10 | 公開日 | 2016-05-25 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structure of spinach photosystem II-LHCII supercomplex at 3.2 A resolution Nature, 534, 2016
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8WYC
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8WYD
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![BU of 8wyd by Molmil](/molmil-images/mine/8wyd) | Cryo-EM structure of DSR2-DSAD1 complex | 分子名称: | Bacillus phage SPbeta DSAD1 protein, SIR2 family protein | 著者 | Zhang, J.T, Jia, N, Liu, X.Y. | 登録日 | 2023-10-30 | 公開日 | 2024-04-10 | 最終更新日 | 2024-04-17 | 実験手法 | ELECTRON MICROSCOPY (2.56 Å) | 主引用文献 | Structural basis for phage-mediated activation and repression of bacterial DSR2 anti-phage defense system. Nat Commun, 15, 2024
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8WYE
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8WY9
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![BU of 8wy9 by Molmil](/molmil-images/mine/8wy9) | |
8WY8
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![BU of 8wy8 by Molmil](/molmil-images/mine/8wy8) | |
8WYB
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![BU of 8wyb by Molmil](/molmil-images/mine/8wyb) | Cryo-EM structure of DSR2 (H171A)-tube-NAD+ complex | 分子名称: | Bacillus phage SPR Tube protein, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SIR2-like domain-containing protein | 著者 | Zhang, J.T, Jia, N, Liu, X.Y. | 登録日 | 2023-10-30 | 公開日 | 2024-04-10 | 最終更新日 | 2024-04-17 | 実験手法 | ELECTRON MICROSCOPY (3.37 Å) | 主引用文献 | Structural basis for phage-mediated activation and repression of bacterial DSR2 anti-phage defense system. Nat Commun, 15, 2024
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6L02
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8WYF
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8WYA
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![BU of 8wya by Molmil](/molmil-images/mine/8wya) | Cryo-EM structure of DSR2-tube complex | 分子名称: | Bacillus phage SPbeta tube protein, SIR2 family protein | 著者 | Zhang, J.T, Jia, N, Liu, X.Y. | 登録日 | 2023-10-30 | 公開日 | 2024-04-10 | 最終更新日 | 2024-04-17 | 実験手法 | ELECTRON MICROSCOPY (3.62 Å) | 主引用文献 | Structural basis for phage-mediated activation and repression of bacterial DSR2 anti-phage defense system. Nat Commun, 15, 2024
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