7DPI
| Plasmodium falciparum cytoplasmic Phenylalanyl-tRNA synthetase in complex with BRD7929 | 分子名称: | (8R,9S,10S)-10-[(dimethylamino)methyl]-N-(4-methoxyphenyl)-9-[4-(2-phenylethynyl)phenyl]-1,6-diazabicyclo[6.2.0]decane-6-carboxamide, MAGNESIUM ION, Phenylalanine--tRNA ligase, ... | 著者 | Manmohan, S, Malhotra, N, Harlos, K, Manickam, Y, Sharma, A. | 登録日 | 2020-12-19 | 公開日 | 2022-03-23 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (3.597 Å) | 主引用文献 | Inhibition of Plasmodium falciparum phenylalanine tRNA synthetase provides opportunity for antimalarial drug development. Structure, 30, 2022
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2WJX
| Crystal structure of the human ionotropic glutamate receptor GluR2 ATD region at 4.1 A resolution | 分子名称: | GLUTAMATE RECEPTOR 2 | 著者 | Clayton, A, Siebold, C, Gilbert, R.J.C, Sutton, G.C, Harlos, K, McIlhinney, R.A.J, Jones, E.Y, Aricescu, A.R. | 登録日 | 2009-06-01 | 公開日 | 2009-08-18 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (4.1 Å) | 主引用文献 | Crystal Structure of the Glur2 Amino-Terminal Domain Provides Insights Into the Architecture and Assembly of Ionotropic Glutamate Receptors. J.Mol.Biol., 392, 2009
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2WNG
| complete extracellular structure of human signal regulatory protein (SIRP) alpha | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE SUBSTRATE 1 | 著者 | Hatherley, D, Graham, S.C, Harlos, K, Stuart, D.I, Barclay, A.N. | 登録日 | 2009-07-09 | 公開日 | 2009-07-21 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | Structure of Signal-Regulatory Protein Alpha: A Link to Antigen Receptor Evolution. J.Biol.Chem., 284, 2009
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2WJW
| Crystal structure of the human ionotropic glutamate receptor GluR2 ATD region at 1.8 A resolution | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, CHLORIDE ION, ... | 著者 | Clayton, A, Siebold, C, Gilbert, R.J.C, Sutton, G.C, Harlos, K, McIlhinney, R.A.J, Jones, E.Y, Aricescu, A.R. | 登録日 | 2009-06-01 | 公開日 | 2009-08-18 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal Structure of the Glur2 Amino-Terminal Domain Provides Insights Into the Architecture and Assembly of Ionotropic Glutamate Receptors. J.Mol.Biol., 392, 2009
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2X11
| Crystal structure of the complete EphA2 ectodomain in complex with ephrin A5 receptor binding domain | 分子名称: | EPHRIN TYPE-A RECEPTOR 2, EPHRIN-A5 | 著者 | Seiradake, E, Harlos, K, Sutton, G, Aricescu, A.R, Jones, E.Y. | 登録日 | 2009-12-21 | 公開日 | 2010-03-16 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (4.83 Å) | 主引用文献 | An Extracellular Steric Seeding Mechanism for Eph-Ephrin Signalling Platform Assembly Nat.Struct.Mol.Biol., 17, 2010
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2W8X
| Structure of the tick ion-channel modulator Ra-KLP | 分子名称: | ACETATE ION, GLYCEROL, IMIDAZOLE, ... | 著者 | Paesen, G.C, Siebold, C, Dallas, M, Peers, C, Harlos, K, Nuttall, P.A, Nunn, M.A, Stuart, D.I, Esnouf, R.M. | 登録日 | 2009-01-20 | 公開日 | 2009-05-05 | 最終更新日 | 2017-06-28 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | An Ion-Channel Modulator from the Saliva of the Brown Ear Tick Has a Highly Modified Kunitz/Bpti Structure. J.Mol.Biol., 389, 2009
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2WFT
| Crystal structure of the human HIP ectodomain | 分子名称: | CHLORIDE ION, HEDGEHOG-INTERACTING PROTEIN, SODIUM ION | 著者 | Bishop, B, Aricescu, A.R, Harlos, K, O'Callaghan, C.A, Jones, E.Y, Siebold, C. | 登録日 | 2009-04-15 | 公開日 | 2009-06-30 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural Insights Into Hedgehog Ligand Sequestration by the Human Hedgehog-Interacting Protein Hip Nat.Struct.Mol.Biol., 16, 2009
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2WS9
| Equine Rhinitis A Virus at Low pH | 分子名称: | P1 | 著者 | Fry, E.E, Tuthill, T.J, Harlos, K, Walter, T.S, Knowles, N.J, Gropelli, E, Rowlands, D.J, Stuart, D.I. | 登録日 | 2009-09-04 | 公開日 | 2010-08-25 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Equine Rhinitis a Virus and its Low Ph Empty Particle: Clues Towards an Aphthovirus Entry Mechanism? Plos Pathog., 5, 2009
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2WFX
| Crystal structure of the complex between human hedgehog-interacting protein HIP and Sonic Hedgehog in the presence of calcium | 分子名称: | CALCIUM ION, HEDGEHOG-INTERACTING PROTEIN, SODIUM ION, ... | 著者 | Bishop, B, Aricescu, A.R, Harlos, K, O'Callaghan, C.A, Jones, E.Y, Siebold, C. | 登録日 | 2009-04-15 | 公開日 | 2009-06-30 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural Insights Into Hedgehog Ligand Sequestration by the Human Hedgehog-Interacting Protein Hip Nat.Struct.Mol.Biol., 16, 2009
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2WFR
| Crystal structure of the N-terminal signalling domain of human Dhh with calcium | 分子名称: | CALCIUM ION, DESERT HEDGEHOG PROTEIN N-PRODUCT, SULFATE ION, ... | 著者 | Bishop, B, Aricescu, A.R, Harlos, K, O'Callaghan, C.A, Jones, E.Y, Siebold, C. | 登録日 | 2009-04-14 | 公開日 | 2009-06-30 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structural Insights Into Hedgehog Ligand Sequestration by the Human Hedgehog-Interacting Protein Hip Nat.Struct.Mol.Biol., 16, 2009
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2WAH
| Crystal Structure of an IgG1 Fc Glycoform (Man9GlcNAc2) | 分子名称: | IG GAMMA-1 CHAIN C REGION, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Crispin, M, Bowden, T.A, Coles, C.H, Harlos, K, Aricescu, A.R, Harvey, D.J, Stuart, D.I, Jones, E.Y. | 登録日 | 2009-02-06 | 公開日 | 2009-03-10 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | 主引用文献 | Carbohydrate and Domain Architecture of an Immature Antibody Glycoform Exhibiting Enhanced Effector Functions J.Mol.Biol., 387, 2009
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2XBO
| Equine Rhinitis A Virus in Complex with its Sialic Acid Receptor | 分子名称: | N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose, P1 | 著者 | Fry, E.E, Tuthill, T.J, Harlos, K, Walter, T.S, Rowlands, D.J, Stuart, D.I. | 登録日 | 2010-04-14 | 公開日 | 2010-09-22 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (4 Å) | 主引用文献 | The Crystal Structure of Equine Rhinitis a Virus in Complex with its Sialic Acid Receptor. J.Gen.Virol., 91, 2010
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2WG4
| Crystal structure of the complex between human hedgehog-interacting protein HIP and sonic hedgehog without calcium | 分子名称: | HEDGEHOG-INTERACTING PROTEIN, SODIUM ION, SONIC HEDGEHOG PROTEIN N-PRODUCT, ... | 著者 | Bishop, B, Aricescu, A.R, Harlos, K, O'Callaghan, C.A, Jones, E.Y, Siebold, C. | 登録日 | 2009-04-15 | 公開日 | 2009-06-30 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | Structural Insights Into Hedgehog Ligand Sequestration by the Human Hedgehog-Interacting Protein Hip Nat.Struct.Mol.Biol., 16, 2009
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2WFF
| Equine Rhinitis A Virus | 分子名称: | P1 | 著者 | Fry, E.E, Tuthill, T.J, Harlos, K, Walter, T.S, Knowles, N.J, Gropelli, E, Rowlands, D.J, Stuart, D.I. | 登録日 | 2009-04-05 | 公開日 | 2010-05-05 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (4 Å) | 主引用文献 | Equine Rhinitis a Virus and its Low Ph Empty Particle: Clues Towards an Aphthovirus Entry Mechanism? Plos Pathog., 5, 2009
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2X10
| Crystal structure of the complete EphA2 ectodomain | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, EPHRIN TYPE-A RECEPTOR 2 | 著者 | Seiradake, E, Harlos, K, Sutton, G, Aricescu, A.R, Jones, E.Y. | 登録日 | 2009-12-21 | 公開日 | 2010-03-16 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | An Extracellular Steric Seeding Mechanism for Eph-Ephrin Signalling Platform Assembly Nat.Struct.Mol.Biol., 17, 2010
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2X46
| Crystal Structure of SeMet Arg r 1 | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ALLERGEN ARG R 1 | 著者 | Paesen, G.C, Siebold, C, Syme, N, Harlos, K, Graham, S.C, Hilger, C, Homans, S.W, Hentges, F, Stuart, D.I. | 登録日 | 2010-01-28 | 公開日 | 2011-02-09 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1 Å) | 主引用文献 | Crystal Structure of the Allergen Arg R 1, a Histamine-Binding Lipocalin from a Soft Tick To be Published
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2WFQ
| Crystal structure of the N-terminal signalling domain of human Dhh without calcium | 分子名称: | DESERT HEDGEHOG PROTEIN N-PRODUCT, SULFATE ION, ZINC ION | 著者 | Bishop, B, Aricescu, A.R, Harlos, K, O'Callaghan, C.A, Jones, E.Y, Siebold, C. | 登録日 | 2009-04-14 | 公開日 | 2009-06-30 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structural Insights Into Hedgehog Ligand Sequestration by the Human Hedgehog-Interacting Protein Hip Nat.Struct.Mol.Biol., 16, 2009
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7BY6
| Plasmodium vivax cytoplasmic Phenylalanyl-tRNA synthetase in complex with BRD1389 | 分子名称: | (3S,4R,8R,9R,10S)-N-(4-cyclopropyloxyphenyl)-10-(methoxymethyl)-3,4-bis(oxidanyl)-9-[4-(2-phenylethynyl)phenyl]-1,6-diazabicyclo[6.2.0]decane-6-carboxamide, MAGNESIUM ION, Phenylalanyl-tRNA synthetase beta chain, ... | 著者 | Malhotra, N, Manmohan, S, Harlos, K, Melillo, B, Schreiber, S.L, Manickam, Y, Sharma, S. | 登録日 | 2020-04-21 | 公開日 | 2020-11-04 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.997 Å) | 主引用文献 | Structural basis of malaria parasite phenylalanine tRNA-synthetase inhibition by bicyclic azetidines. Nat Commun, 12, 2021
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7EL5
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5L81
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