5ZGM
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![BU of 5zgm by Molmil](/molmil-images/mine/5zgm) | Crystal Structure of Parvalbumin SPVI, the Major Allergens in Mustelus griseus | Descriptor: | CALCIUM ION, Parvalbumin SPVI, SULFATE ION | Authors: | Yang, R.Q, Chen, Y.L, Jin, T.C, Cao, M.J. | Deposit date: | 2018-03-09 | Release date: | 2018-08-01 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.399 Å) | Cite: | Purification, Characterization, and Crystal Structure of Parvalbumins, the Major Allergens in Mustelus griseus. J. Agric. Food Chem., 66, 2018
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3LA7
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![BU of 3la7 by Molmil](/molmil-images/mine/3la7) | Crystal structure of NtcA in apo-form | Descriptor: | Global nitrogen regulator, octyl beta-D-glucopyranoside | Authors: | Zhao, M.X, Jiang, Y.L, He, Y.X, Chen, Y.F, Teng, Y.B, Zhang, C.C, Chen, Y.X, Zhou, C.Z. | Deposit date: | 2010-01-06 | Release date: | 2010-09-01 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural basis for the allosteric control of the global transcription factor NtcA by the nitrogen starvation signal 2-oxoglutarate. Proc.Natl.Acad.Sci.USA, 107, 2010
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4E0I
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![BU of 4e0i by Molmil](/molmil-images/mine/4e0i) | Crystal structure of the C30S/C133S mutant of Erv1 from Saccharomyces cerevisiae | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Mitochondrial FAD-linked sulfhydryl oxidase ERV1 | Authors: | Guo, P.C, Ma, J.D, Jiang, Y.L, Wang, S.J, Hu, T.T, Chen, Y.X, Zhou, C.Z. | Deposit date: | 2012-03-04 | Release date: | 2012-08-29 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure of yeast sulfhydryl oxidase erv1 reveals electron transfer of the disulfide relay system in the mitochondrial intermembrane space J.Biol.Chem., 287, 2012
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4E0H
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![BU of 4e0h by Molmil](/molmil-images/mine/4e0h) | Crystal structure of FAD binding domain of Erv1 from Saccharomyces cerevisiae | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Mitochondrial FAD-linked sulfhydryl oxidase ERV1 | Authors: | Guo, P.C, Ma, J.D, Jiang, Y.L, Wang, S.J, Hu, T.T, Chen, Y.X, Zhou, C.Z. | Deposit date: | 2012-03-04 | Release date: | 2012-08-29 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of yeast sulfhydryl oxidase erv1 reveals electron transfer of the disulfide relay system in the mitochondrial intermembrane space J.Biol.Chem., 287, 2012
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3LA3
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![BU of 3la3 by Molmil](/molmil-images/mine/3la3) | Crystal structure of NtcA in complex with 2,2-difluoropentanedioic acid | Descriptor: | 2,2-difluoropentanedioic acid, Global nitrogen regulator | Authors: | Zhao, M.X, Jiang, Y.L, He, Y.X, Chen, Y.F, Teng, Y.B, Chen, Y.X, Zhang, C.C, Zhou, C.Z. | Deposit date: | 2010-01-06 | Release date: | 2010-07-14 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis for the allosteric control of the global transcription factor NtcA by the nitrogen starvation signal 2-oxoglutarate. Proc.Natl.Acad.Sci.USA, 107, 2010
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7BZV
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![BU of 7bzv by Molmil](/molmil-images/mine/7bzv) | |
6LR0
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![BU of 6lr0 by Molmil](/molmil-images/mine/6lr0) | structure of human bile salt exporter ABCB11 | Descriptor: | Bile salt export pump | Authors: | Wang, L, Hou, W.T, Chen, L, Jiang, Y.L, Xu, D, Sun, L.F, Zhou, C.Z, Chen, Y. | Deposit date: | 2020-01-15 | Release date: | 2020-04-15 | Last modified: | 2023-01-18 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Cryo-EM structure of human bile salts exporter ABCB11. Cell Res., 30, 2020
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5ZH6
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![BU of 5zh6 by Molmil](/molmil-images/mine/5zh6) | Crystal structure of Parvalbumin SPV-II of Mustelus griseus | Descriptor: | CALCIUM ION, Parvalbumin SPV-II, SULFATE ION | Authors: | Yang, R.Q, Chen, Y.L, Jin, T.C, Cao, M.J. | Deposit date: | 2018-03-11 | Release date: | 2018-08-01 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | Purification, Characterization, and Crystal Structure of Parvalbumins, the Major Allergens in Mustelus griseus. J. Agric. Food Chem., 66, 2018
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5ZIT
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![BU of 5zit by Molmil](/molmil-images/mine/5zit) | Crystal structure of human Enterovirus D68 RdRp in complex with NADPH | Descriptor: | DI(HYDROXYETHYL)ETHER, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, RdRp | Authors: | Wang, M.L, Li, L, Chen, Y.P, Jiang, H, Zhang, Y, Su, D. | Deposit date: | 2018-03-17 | Release date: | 2019-04-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.196 Å) | Cite: | Structure of the enterovirus D68 RNA-dependent RNA polymerase in complex with NADPH implicates an inhibitor binding site in the RNA template tunnel. J.Struct.Biol., 2020
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7D68
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![BU of 7d68 by Molmil](/molmil-images/mine/7d68) | Cryo-EM structure of the human glucagon-like peptide-2 receptor-Gs protein complex | Descriptor: | Glucagon-like peptide 2 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Sun, W, Chen, L, Zhou, Q, Zhao, L, Zhang, H, Cong, Z, Shen, D, Zhao, F, Zhou, F, Cai, X, Chen, Y, Zhou, Y, Gadgaard, S, van der Velden, W.J, Zhao, S, Jiang, Y, Rosenkilde, M.M, Yang, D, Xu, H.E, Zhang, Y, Wang, M. | Deposit date: | 2020-09-29 | Release date: | 2020-12-16 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | A unique hormonal recognition feature of the human glucagon-like peptide-2 receptor. Cell Res., 30, 2020
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6K2Q
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![BU of 6k2q by Molmil](/molmil-images/mine/6k2q) | Aeromonas hydrophila MtaN-2 complexed with adenine | Descriptor: | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, ADENINE | Authors: | Chen, J, Liu, W, Wang, L, Shang, F, Lan, J, Chen, Y, Xu, Y. | Deposit date: | 2019-05-15 | Release date: | 2019-05-29 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of Aeromonas hydrophila Cytoplasmic 5'-Methylthioadenosine/S-Adenosylhomocysteine Nucleosidase. Biochemistry, 58, 2019
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2H3R
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![BU of 2h3r by Molmil](/molmil-images/mine/2h3r) | Crystal structure of ORF52 from Murid herpesvirus 4 (MuHV-4) (Murine gammaherpesvirus 68). Northeast Structural Genomics Consortium target MhR28B. | Descriptor: | Hypothetical protein BQLF2 | Authors: | Benach, J, Chen, Y, Seetharaman, J, Janjua, H, Xiao, R, Cunningham, K, Ma, L.-C, Ho, C.K, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2006-05-23 | Release date: | 2006-08-15 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of ORF52 from Murid herpesvirus 4 (MuHV-4) (Murine gammaherpesvirus 68). Northeast Structural Genomics Consortium target MhR28B. To be Published
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3LA2
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![BU of 3la2 by Molmil](/molmil-images/mine/3la2) | Crystal structure of NtcA in complex with 2-oxoglutarate | Descriptor: | 2-OXOGLUTARIC ACID, Global nitrogen regulator | Authors: | Zhao, M.X, Jiang, Y.L, He, Y.X, Chen, Y.F, Teng, Y.B, Chen, Y.X, Zhang, C.C, Zhou, C.Z. | Deposit date: | 2010-01-06 | Release date: | 2010-07-14 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis for the allosteric control of the global transcription factor NtcA by the nitrogen starvation signal 2-oxoglutarate. Proc.Natl.Acad.Sci.USA, 107, 2010
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7CBY
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![BU of 7cby by Molmil](/molmil-images/mine/7cby) | Structure of FOXG1 DNA binding domain bound to DBE2 DNA site | Descriptor: | DI(HYDROXYETHYL)ETHER, DNA (5'-D(*CP*AP*AP*AP*AP*TP*GP*TP*AP*AP*AP*CP*AP*AP*GP*A)-3'), DNA (5'-D(*TP*CP*TP*TP*GP*TP*TP*TP*AP*CP*AP*TP*TP*TP*TP*G)-3'), ... | Authors: | Dai, S.Y, Li, J, Chen, Y.H. | Deposit date: | 2020-06-15 | Release date: | 2020-10-28 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.646 Å) | Cite: | Structural Basis for DNA Recognition by FOXG1 and the Characterization of Disease-causing FOXG1 Mutations. J.Mol.Biol., 432, 2020
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7Y4T
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![BU of 7y4t by Molmil](/molmil-images/mine/7y4t) | Crystal structure of cMET kinase domain bound by compound 9I | Descriptor: | 2-[2-[3-(1-methylpyrazol-4-yl)quinolin-6-yl]ethyl]-6-(3-nitrophenyl)pyridazin-3-one, Hepatocyte growth factor receptor | Authors: | Qu, L.Z, Chen, Y.H. | Deposit date: | 2022-06-16 | Release date: | 2022-11-23 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.16 Å) | Cite: | Discovery of D6808, a Highly Selective and Potent Macrocyclic c-Met Inhibitor for Gastric Cancer Harboring MET Gene Alteration Treatment. J.Med.Chem., 65, 2022
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7Y4U
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![BU of 7y4u by Molmil](/molmil-images/mine/7y4u) | Crystal structure of cMET kinase domain bound by compound 9Y | Descriptor: | Hepatocyte growth factor receptor, ~{N}-methyl-4-[1-[2-[3-(1-methylpyrazol-4-yl)quinolin-6-yl]ethyl]-6-oxidanylidene-pyridazin-3-yl]-2-(trifluoromethyl)benzamide | Authors: | Qu, L.Z, Chen, Y.H. | Deposit date: | 2022-06-16 | Release date: | 2022-11-23 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | Discovery of D6808, a Highly Selective and Potent Macrocyclic c-Met Inhibitor for Gastric Cancer Harboring MET Gene Alteration Treatment. J.Med.Chem., 65, 2022
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7FIN
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![BU of 7fin by Molmil](/molmil-images/mine/7fin) | Cryo-EM structure of the GIPR/GLP-1R/GCGR triagonist peptide 20-bound human GIPR-Gs complex | Descriptor: | CHOLESTEROL, GAMMA-L-GLUTAMIC ACID, Gastric inhibitory polypeptide receptor,human glucose-dependent insulinotropic polypeptide receptor, ... | Authors: | Zhao, F.h, Zhou, Q.T, Cong, Z.T, Hang, K.N, Zou, X.Y, Zhang, C, Chen, Y, Dai, A.T, Liang, A.Y, Ming, Q.Q, Wang, M, Chen, L.N, Xu, P.Y, Chang, R.L, Feng, W.B, Xia, T, Zhang, Y, Wu, B.L, Yang, D.H, Zhao, L.H, Xu, H.E, Wang, M.W. | Deposit date: | 2021-07-31 | Release date: | 2022-02-23 | Last modified: | 2022-03-16 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural insights into multiplexed pharmacological actions of tirzepatide and peptide 20 at the GIP, GLP-1 or glucagon receptors. Nat Commun, 13, 2022
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7FIY
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![BU of 7fiy by Molmil](/molmil-images/mine/7fiy) | Cryo-EM structure of the tirzepatide-bound human GIPR-Gs complex | Descriptor: | CHOLESTEROL, Gastric inhibitory polypeptide receptor,Gastric inhibitory polypeptide receptor,human glucose-dependent insulinotropic polypeptide receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Zhao, F.H, Zhou, Q.T, Cong, Z.T, Hang, K.N, Zou, X.Y, Zhang, C, Chen, Y, Dai, A.T, Liang, A.Y, Ming, Q.Q, Wang, M, Chen, L.N, Xu, P.Y, Chang, R.L, Feng, W.B, Xia, T, Zhang, Y, Wu, B.L, Yang, D.H, Zhao, L.H, Xu, H.E, Wang, M.W. | Deposit date: | 2021-08-01 | Release date: | 2022-03-02 | Last modified: | 2022-03-16 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural insights into multiplexed pharmacological actions of tirzepatide and peptide 20 at the GIP, GLP-1 or glucagon receptors. Nat Commun, 13, 2022
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6J08
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![BU of 6j08 by Molmil](/molmil-images/mine/6j08) | Crystal structure of human MAJIN and TERB2 | Descriptor: | Membrane-anchored junction protein, Telomere repeats-binding bouquet formation protein 2 | Authors: | Wang, Y, Chen, Y, Wu, J, Huang, C, Lei, M. | Deposit date: | 2018-12-21 | Release date: | 2019-02-27 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | The meiotic TERB1-TERB2-MAJIN complex tethers telomeres to the nuclear envelope. Nat Commun, 10, 2019
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7FBI
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![BU of 7fbi by Molmil](/molmil-images/mine/7fbi) | Cryo-EM structure of EBV gB in complex with nAbs 3A3 and 3A5 | Descriptor: | 3A3 heavy chain, 3A3 light chain, 3A5 heavy chain, ... | Authors: | Zheng, Q, Li, S, Zha, Z, Hong, J, Chen, Y, Zhang, X. | Deposit date: | 2021-07-10 | Release date: | 2022-07-13 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Cryo-EM structure of EBV gB in complex with nAbs 3A3 and 3A5 To Be Published
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6K63
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![BU of 6k63 by Molmil](/molmil-images/mine/6k63) | The crystal structure of cytidine deaminase from Klebsiella pneumoniae | Descriptor: | 1,4-DIETHYLENE DIOXIDE, Cytidine deaminase, ZINC ION | Authors: | Liu, W, Shang, F, Lan, J, Chen, Y, Wang, L, Xu, Y. | Deposit date: | 2019-06-01 | Release date: | 2019-07-31 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.073 Å) | Cite: | Biochemical and structural analysis of the Klebsiella pneumoniae cytidine deaminase CDA. Biochem.Biophys.Res.Commun., 519, 2019
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7D6C
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![BU of 7d6c by Molmil](/molmil-images/mine/7d6c) | Crystal structure of CcmM N-terminal domain in complex with CcmN | Descriptor: | Carbon dioxide concentrating mechanism protein CcmM, Carboxysome assembly protein CcmN | Authors: | Sun, H, Cui, N, Han, S.J, Chen, Z.P, Xia, L.Y, Chen, Y, Jiang, Y.L, Zhou, C.Z. | Deposit date: | 2020-09-30 | Release date: | 2021-08-04 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.89 Å) | Cite: | Complex structure reveals CcmM and CcmN form a heterotrimeric adaptor in beta-carboxysome. Protein Sci., 30, 2021
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6LC1
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![BU of 6lc1 by Molmil](/molmil-images/mine/6lc1) | |
7YTJ
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![BU of 7ytj by Molmil](/molmil-images/mine/7ytj) | Cryo-EM structure of VTC complex | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, INOSITOL HEXAKISPHOSPHATE, PHOSPHATE ION, ... | Authors: | Guan, Z.Y, Chen, J, Liu, R.W, Chen, Y.K, Xing, Q, Du, Z.M, Liu, Z. | Deposit date: | 2022-08-15 | Release date: | 2023-02-22 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | The cytoplasmic synthesis and coupled membrane translocation of eukaryotic polyphosphate by signal-activated VTC complex. Nat Commun, 14, 2023
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2F9C
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![BU of 2f9c by Molmil](/molmil-images/mine/2f9c) | Crystal structure of YDCK from Salmonella cholerae. NESG target SCR6 | Descriptor: | CESIUM ION, Hypothetical protein YDCK | Authors: | Benach, J, Chen, Y, Vorobiev, S.M, Seetharaman, J, Janjua, H, Cooper, B, Acton, X.T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2005-12-05 | Release date: | 2005-12-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of YDCK from Salmonella cholerae NESG target SCR6. To be Published
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