8KAI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8kai by Molmil](/molmil-images/mine/8kai) | |
8KAH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8kah by Molmil](/molmil-images/mine/8kah) | |
4HCA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4hca by Molmil](/molmil-images/mine/4hca) | DNA binding by GATA transcription factor-complex 1 | 分子名称: | DNA (5'-D(*AP*AP*TP*GP*TP*CP*CP*AP*TP*CP*TP*GP*AP*TP*AP*AP*GP*AP*CP*G)-3'), DNA (5'-D(*TP*TP*CP*GP*TP*CP*TP*TP*AP*TP*CP*AP*GP*AP*TP*GP*GP*AP*CP*A)-3'), Trans-acting T-cell-specific transcription factor GATA-3, ... | 著者 | Chen, Y, Bates, D.L, Dey, R, Chen, L. | 登録日 | 2012-09-28 | 公開日 | 2012-12-05 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | DNA Binding by GATA Transcription Factor Suggests Mechanisms of DNA Looping and Long-Range Gene Regulation. Cell Rep, 2, 2012
|
|
4HC7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4hc7 by Molmil](/molmil-images/mine/4hc7) | Crystal structure of the full DNA binding domain of GATA3-complex 2 | 分子名称: | DNA (5'-D(*AP*AP*GP*GP*TP*TP*AP*TP*CP*TP*CP*TP*GP*AP*TP*TP*TP*AP*GP*G)-3'), DNA (5'-D(*TP*TP*CP*CP*TP*AP*AP*AP*TP*CP*AP*GP*AP*GP*AP*TP*AP*AP*CP*C)-3'), Trans-acting T-cell-specific transcription factor GATA-3, ... | 著者 | Chen, Y, Bates, D.L, Dey, R, Chen, L. | 登録日 | 2012-09-28 | 公開日 | 2012-12-05 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | DNA Binding by GATA Transcription Factor Suggests Mechanisms of DNA Looping and Long-Range Gene Regulation. Cell Rep, 2, 2012
|
|
4HC9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4hc9 by Molmil](/molmil-images/mine/4hc9) | DNA binding by GATA transcription factor-complex 3 | 分子名称: | DNA (5'-D(*AP*AP*GP*GP*TP*TP*AP*TP*CP*TP*CP*TP*GP*AP*TP*TP*TP*AP*GP*G)-3'), DNA (5'-D(*TP*TP*CP*CP*TP*AP*AP*AP*TP*CP*AP*GP*AP*GP*AP*TP*AP*AP*CP*C)-3'), Trans-acting T-cell-specific transcription factor GATA-3, ... | 著者 | Chen, Y, Bates, D.L, Dey, R, Chen, L. | 登録日 | 2012-09-28 | 公開日 | 2012-12-05 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | DNA Binding by GATA Transcription Factor Suggests Mechanisms of DNA Looping and Long-Range Gene Regulation. Cell Rep, 2, 2012
|
|
8KAK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8kak by Molmil](/molmil-images/mine/8kak) | |
5XS1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5xs1 by Molmil](/molmil-images/mine/5xs1) | |
8I4B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8i4b by Molmil](/molmil-images/mine/8i4b) | Cryo-EM structure of apo-form ABCC4 | 分子名称: | ATP-binding cassette sub-family C member 4 | 著者 | Chen, Y, Wang, L, Hou, W.T, Zhou, C.Z, Chen, Y, Li, Q. | 登録日 | 2023-01-19 | 公開日 | 2023-05-24 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.13 Å) | 主引用文献 | Cryo-EM structure ofABCC4 Nat Cardiovasc Res, 2023
|
|
8I4A
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8i4a by Molmil](/molmil-images/mine/8i4a) | Cryo-EM structure of dipyridamole-bound ABCC4 | 分子名称: | 2-[[2-[bis(2-hydroxyethyl)amino]-4,8-di(piperidin-1-yl)pyrimido[5,4-d]pyrimidin-6-yl]-(2-hydroxyethyl)amino]ethanol, ATP-binding cassette sub-family C member 4 | 著者 | Chen, Y, Wang, L, Hou, W.T, Zhou, C.Z, Chen, Y, Li, Q. | 登録日 | 2023-01-19 | 公開日 | 2023-05-24 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Cryo-EM structure ofABCC4 Nat Cardiovasc Res, 2023
|
|
8I4C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8i4c by Molmil](/molmil-images/mine/8i4c) | Cryo-EM structure of U46619-bound ABCC4 | 分子名称: | (5Z)-7-{(1R,4S,5S,6R)-6-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-2-oxabicyclo[2.2.1]hept-5-yl}hept-5-enoic acid, ATP-binding cassette sub-family C member 4 | 著者 | Chen, Y, Wang, L, Hou, W.T, Zhou, C.Z, Chen, Y, Li, Q. | 登録日 | 2023-01-19 | 公開日 | 2023-05-24 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.08 Å) | 主引用文献 | Cryo-EM structure ofABCC4 Nat Cardiovasc Res, 2023
|
|
8J3Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8j3z by Molmil](/molmil-images/mine/8j3z) | Cryo-EM structure of ATP-U46619-bound ABCC4 | 分子名称: | (5Z)-7-{(1R,4S,5S,6R)-6-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-2-oxabicyclo[2.2.1]hept-5-yl}hept-5-enoic acid, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 4, ... | 著者 | Chen, Y, Wang, L, Hou, W.T, Zhou, C.Z, Chen, Y, Li, Q. | 登録日 | 2023-04-18 | 公開日 | 2023-05-24 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.17 Å) | 主引用文献 | Cryo-EM structure ofABCC4 Nat Cardiovasc Res, 2023
|
|
7MSU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7msu by Molmil](/molmil-images/mine/7msu) | Crystal structure of an archaeal CNNM, MtCorB, CBS-pair domain in complex with Mg2+-ATP | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, Hemolysin, ... | 著者 | Chen, Y.S, Gehring, K. | 登録日 | 2021-05-12 | 公開日 | 2021-06-16 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | 主引用文献 | Crystal structure of an archaeal CorB magnesium transporter. Nat Commun, 12, 2021
|
|
7NAB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7nab by Molmil](/molmil-images/mine/7nab) | Crystal structure of human neutralizing mAb CV3-25 binding to SARS-CoV-2 S MPER peptide 1140-1165 | 分子名称: | CITRIC ACID, CV3-25 Fab Heavy Chain, CV3-25 Fab Light Chain, ... | 著者 | Chen, Y, Tolbert, W.D, Pazgier, M. | 登録日 | 2021-06-21 | 公開日 | 2021-12-08 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Structural basis and mode of action for two broadly neutralizing antibodies against SARS-CoV-2 emerging variants of concern. Cell Rep, 38, 2022
|
|
4PZQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4pzq by Molmil](/molmil-images/mine/4pzq) | Crystal Structure of CCG DNA repeats | 分子名称: | COBALT (II) ION, DNA (5'-D(*TP*CP*CP*GP*CP*CP*GP*CP*CP*GP*A)-3') | 著者 | Chen, Y.W, Hou, M.H. | 登録日 | 2014-03-31 | 公開日 | 2015-01-07 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | 主引用文献 | Structural basis for the identification of an i-motif tetraplex core with a parallel-duplex junction as a structural motif in CCG triplet repeats Angew.Chem.Int.Ed.Engl., 53, 2014
|
|
8J3W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8j3w by Molmil](/molmil-images/mine/8j3w) | Cryo-EM structure of aspirin-bound ABCC4 | 分子名称: | 2-(ACETYLOXY)BENZOIC ACID, ATP-binding cassette sub-family C member 4 | 著者 | Chen, Y, Wang, L, Hou, W.T, Zhou, C.Z, Chen, Y, Li, Q. | 登録日 | 2023-04-18 | 公開日 | 2023-05-24 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.07 Å) | 主引用文献 | Cryo-EM structure ofABCC4 Nat Cardiovasc Res, 2023
|
|
8UAP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8uap by Molmil](/molmil-images/mine/8uap) | |
8UAQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8uaq by Molmil](/molmil-images/mine/8uaq) | Crystal Structure of Human G Protein-Coupled Receptor Kinase 5 in Complex with GRL018-21 | 分子名称: | (3Z)-N-[(1R)-1-(4-fluorophenyl)ethyl]-3-[(4-{[(2S)-2-(furan-2-yl)-2-hydroxyacetyl]amino}-3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-2-oxo-2,3-dihydro-1H-indole-5-carboxamide, G protein-coupled receptor kinase 5 | 著者 | Chen, Y, Tesmer, J.J.G. | 登録日 | 2023-09-21 | 公開日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Development of a new class of potent and highly selective G protein-coupled receptor kinase 5 inhibitors and structural insight from crystal structures of inhibitor complexes. Eur.J.Med.Chem., 264, 2023
|
|
4HJE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4hje by Molmil](/molmil-images/mine/4hje) | Crystal structure of p53 core domain in complex with DNA | 分子名称: | Cellular tumor antigen p53, DNA (5'-D(*AP*GP*GP*CP*TP*TP*GP*TP*CP*TP*CP*TP*AP*AP*CP*TP*TP*GP*TP*GP*A)-3'), DNA (5'-D(*TP*CP*AP*CP*AP*AP*GP*TP*TP*AP*GP*AP*GP*AP*CP*AP*AP*GP*CP*CP*T)-3'), ... | 著者 | Chen, Y, Chen, L. | 登録日 | 2012-10-12 | 公開日 | 2013-07-17 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.907 Å) | 主引用文献 | Structure of p53 binding to the BAX response element reveals DNA unwinding and compression to accommodate base-pair insertion. Nucleic Acids Res., 41, 2013
|
|
8J54
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8j54 by Molmil](/molmil-images/mine/8j54) | Crystal structure of RXR/DR2 complex | 分子名称: | DNA (5'-D(*CP*AP*TP*GP*AP*CP*CP*TP*AP*CP*TP*GP*AP*CP*CP*TP*AP*G)-3'), DNA (5'-D(*CP*TP*AP*GP*GP*TP*CP*AP*GP*TP*AP*GP*GP*TP*CP*AP*TP*G)-3'), Retinoic acid receptor RXR, ... | 著者 | Chen, Y, Jiang, L. | 登録日 | 2023-04-21 | 公開日 | 2024-01-17 | 最終更新日 | 2024-04-17 | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | 主引用文献 | Structural characterization of the DNA binding mechanism of retinoic acid-related orphan receptor gamma. Structure, 32, 2024
|
|
7M1U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7m1u by Molmil](/molmil-images/mine/7m1u) | Crystal structure of an archaeal CNNM, MtCorB, R235L mutant with C-terminal deletion | 分子名称: | Hemolysin, contains CBS domains | 著者 | Chen, Y.S, Kozlov, G, Gehring, K. | 登録日 | 2021-03-15 | 公開日 | 2021-06-16 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | Crystal structure of an archaeal CorB magnesium transporter. Nat Commun, 12, 2021
|
|
7M1T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7m1t by Molmil](/molmil-images/mine/7m1t) | Crystal structure of an archaeal CNNM, MtCorB, with C-terminal deletion in complex with Mg2+-ATP | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Hemolysin, contains CBS domains, ... | 著者 | Chen, Y.S, Kozlov, G, Gehring, K. | 登録日 | 2021-03-15 | 公開日 | 2021-06-16 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.26 Å) | 主引用文献 | Crystal structure of an archaeal CorB magnesium transporter. Nat Commun, 12, 2021
|
|
5VAE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5vae by Molmil](/molmil-images/mine/5vae) | |
5VAF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5vaf by Molmil](/molmil-images/mine/5vaf) | |
6N7E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6n7e by Molmil](/molmil-images/mine/6n7e) | |
8DKS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8dks by Molmil](/molmil-images/mine/8dks) | IRAK4 IN COMPLEX WITH COMPOUND #3 | 分子名称: | (1S,2S,3R,4R)-3-({2-[3-(pyrrolidine-1-carbonyl)anilino]thieno[3,2-d]pyrimidin-4-yl}amino)bicyclo[2.2.1]hept-5-ene-2-carboxamide, BETA-MERCAPTOETHANOL, Interleukin-1 receptor-associated kinase 4 | 著者 | Chen, Y, Lin, N. | 登録日 | 2022-07-06 | 公開日 | 2022-08-03 | 最終更新日 | 2022-08-17 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Bicyclic pyrimidine compounds as potent IRAK4 inhibitors. Bioorg.Med.Chem.Lett., 73, 2022
|
|