6X67
| Cryo-EM structure of piggyBac transposase strand transfer complex (STC) | Descriptor: | CALCIUM ION, DNA (37-MER), DNA (47-MER), ... | Authors: | Chen, Q, Hickman, A.B, Dyda, F. | Deposit date: | 2020-05-27 | Release date: | 2020-07-22 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.47 Å) | Cite: | Structural basis of seamless excision and specific targeting by piggyBac transposase Nat Commun, 11, 2020
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4WVR
| Crystal structure of Dscam1 Ig7 domain, isoform 5 | Descriptor: | Down syndrome cell adhesion molecule, isoform AK | Authors: | Chen, Q, Yu, Y, Li, S, Cheng, L. | Deposit date: | 2014-11-07 | Release date: | 2015-11-18 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.948 Å) | Cite: | Structural basis of Dscam1 homodimerization: Insights into context constraint for protein recognition Sci Adv, 2, 2016
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4X83
| Crystal structure of Dscam1 isoform 7.44, N-terminal four Ig domains | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | Authors: | Chen, Q, Yu, Y, Li, S.A, Cheng, L. | Deposit date: | 2014-12-10 | Release date: | 2015-12-16 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.902 Å) | Cite: | Structural basis of Dscam1 homodimerization: Insights into context constraint for protein recognition Sci Adv, 2, 2016
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4X9B
| Crystal structure of Dscam1 isoform 4.44, N-terminal four Ig domains | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Down syndrome cell adhesion molecule, isoform 4.44, ... | Authors: | Chen, Q, Yu, Y, Li, S.A, Cheng, L. | Deposit date: | 2014-12-11 | Release date: | 2015-12-16 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis of Dscam1 homodimerization: Insights into context constraint for protein recognition Sci Adv, 2, 2016
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4X9F
| Crystal structure of Dscam1 isoform 6.9, N-terminal four Ig domains | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Down Syndrome Cell Adhesion Molecule isoform 6.9, GLYCEROL, ... | Authors: | Chen, Q, Yu, Y, Li, S.A, Cheng, L. | Deposit date: | 2014-12-11 | Release date: | 2015-12-16 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structural basis of Dscam1 homodimerization: Insights into context constraint for protein recognition Sci Adv, 2, 2016
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6E5V
| human mGlu8 receptor amino terminal domain in complex with (S)-3,4-Dicarboxyphenylglycine (DCPG) | Descriptor: | 4-[(S)-amino(carboxy)methyl]benzene-1,2-dicarboxylic acid, CHLORIDE ION, Metabotropic glutamate receptor 8 | Authors: | Chen, Q, Ho, J.D, Ashok, S, Vargas, M.C, Wang, J, Atwell, S, Bures, M, Schkeryantz, J.M, Monn, J.A, Hao, J. | Deposit date: | 2018-07-23 | Release date: | 2018-11-07 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Structural Basis for ( S)-3,4-Dicarboxyphenylglycine (DCPG) As a Potent and Subtype Selective Agonist of the mGlu8Receptor. J. Med. Chem., 61, 2018
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4X8X
| Crystal structure of Dscam1 isoform 1.9, N-terminal four Ig domains | Descriptor: | Down Syndrome cell adhesion molecule isoform 1.9, GLYCEROL, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Chen, Q. | Deposit date: | 2014-12-11 | Release date: | 2015-12-16 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis of Dscam1 homodimerization: Insights into context constraint for protein recognition Sci Adv, 2, 2016
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6LFD
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6LF4
| Crystal structure of VMB-1 bound to hydrolyzed meropenem | Descriptor: | (2~{S},3~{R},4~{S})-2-[(2~{S},3~{R})-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-4-[(3~{S},5~{S})-5-(dimethylcarbamoy l)pyrrolidin-3-yl]sulfanyl-3-methyl-3,4-dihydro-2~{H}-pyrrole-5-carboxylic acid, VMB-1 metallo-beta-lactamase, ZINC ION | Authors: | Cheng, Q, Chen, S. | Deposit date: | 2019-11-28 | Release date: | 2020-03-25 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Crystal structure of VMB-1 bound to hydrolyzed meropenem To Be Published
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4XB7
| Crystal structure of Dscam1 isoform 4.4, N-terminal four Ig domains | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Down syndrome cell adhesion molecule, isoform 4.4, ... | Authors: | Chen, Q, Yu, Y, Li, S.A, Cheng, L. | Deposit date: | 2014-12-16 | Release date: | 2015-12-16 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (4.004 Å) | Cite: | Structural basis of Dscam1 homodimerization: Insights into context constraint for protein recognition Sci Adv, 2, 2016
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4X9I
| Crystal structure of Dscam1 isoform 9.44, N-terminal four Ig domains | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Down Syndrome Cell Adhesion Molecule, isoform 9.44, ... | Authors: | Chen, Q, Yu, Y, Li, S.A, cheng, L. | Deposit date: | 2014-12-11 | Release date: | 2015-12-16 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.904 Å) | Cite: | Structural basis of Dscam1 homodimerization: Insights into context constraint for protein recognition Sci Adv, 2, 2016
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4XB8
| Crystal structure of Dscam1 isoform 9.44, N-terminal four Ig domains (with zinc) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Down Syndrome Cell Adhesion Molecule, ... | Authors: | Chen, Q, Yu, Y, Li, S.A, cheng, L. | Deposit date: | 2014-12-16 | Release date: | 2015-12-16 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.202 Å) | Cite: | Structural basis of Dscam1 homodimerization: Insights into context constraint for protein recognition Sci Adv, 2, 2016
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4X9G
| Crystal structure of Dscam1 isoform 6.44, N-terminal four Ig domains | Descriptor: | Down Syndrome Cell Adhesion Molecule isoform 6.44, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Chen, Q, Yu, Y, Li, S.A, Cheng, L. | Deposit date: | 2014-12-11 | Release date: | 2015-12-16 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.403 Å) | Cite: | Structural basis of Dscam1 homodimerization: Insights into context constraint for protein recognition Sci Adv, 2, 2016
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4X5L
| Crystal structure of Dscam1 Ig7 domain, isoform 9 | Descriptor: | Down syndrome cell adhesion molecule, isoform AM, SODIUM ION | Authors: | Chen, Q, Yu, Y, Li, S.A, Cheng, L. | Deposit date: | 2014-12-05 | Release date: | 2015-12-09 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.374 Å) | Cite: | Structural basis of Dscam1 homodimerization: Insights into context constraint for protein recognition Sci Adv, 2, 2016
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5SXU
| X-ray structure of 2-bromoethanol bound to a pentameric ligand gated ion channel (ELIC) in a desensitized state | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-BROMOETHANOL, 3-AMINOPROPANE, ... | Authors: | Chen, Q, Kinde, M, Cohen, A, Xu, Y, Tang, P. | Deposit date: | 2016-08-10 | Release date: | 2017-06-21 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural Basis of Alcohol Inhibition of the Pentameric Ligand-Gated Ion Channel ELIC. Structure, 25, 2017
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5SXV
| X-ray structure of 2-bromoethanol bound to a pentameric ligand gated ion channel (ELIC) in a resting state | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-BROMOETHANOL, Cys-loop ligand-gated ion channel | Authors: | Chen, Q, Kinde, M, Cohen, A, Xu, Y, Tang, P. | Deposit date: | 2016-08-10 | Release date: | 2017-06-21 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Structural Basis of Alcohol Inhibition of the Pentameric Ligand-Gated Ion Channel ELIC. Structure, 25, 2017
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1YFZ
| Novel IMP Binding in Feedback Inhibition of Hypoxanthine-Guanine Phosphoribosyltransferase from Thermoanaerobacter tengcongensis | Descriptor: | ACETATE ION, Hypoxanthine-guanine phosphoribosyltransferase, INOSINIC ACID, ... | Authors: | Chen, Q, Liang, Y, Su, X, Gu, X, Zheng, X, Luo, M. | Deposit date: | 2005-01-04 | Release date: | 2005-05-10 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Alternative IMP Binding in Feedback Inhibition of Hypoxanthine-Guanine Phosphoribosyltransferase from Thermoanaerobacter tengcongensis. J.Mol.Biol., 348, 2005
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6LDU
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6LE7
| Crystal structure of nematode family I chitinase,CeCht1, in complex with dihydropyrrolopyrazol-6-one derivate 2 | Descriptor: | (4R)-3-(2-hydroxyphenyl)-4-(3-methoxy-4-propoxy-phenyl)-5-(pyridin-3-ylmethyl)-1,4-dihydropyrrolo[3,4-c]pyrazol-6-one, Probable endochitinase | Authors: | Chen, Q, Yang, Q, Zhou, Y. | Deposit date: | 2019-11-24 | Release date: | 2021-05-26 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.85753441 Å) | Cite: | Crystal structure of nematode family I chitinase,CeCht1, in complex with dihydropyrrolopyrazol-6-one derivate 2 To Be Published
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6LE8
| Crystal structure of nematode family I chitinase,CeCht1, in complex with dihydropyrrolopyrazol-6-one derivate 1 | Descriptor: | (4R)-4-(4-ethoxyphenyl)-3-(2-hydroxyphenyl)-5-(pyridin-3-ylmethyl)-1,4-dihydropyrrolo[3,4-c]pyrazol-6-one, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, ... | Authors: | Chen, Q, Yang, Q, Zhou, Y. | Deposit date: | 2019-11-24 | Release date: | 2021-05-26 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.39909327 Å) | Cite: | Crystal structure of nematode family I chitinase,CeCht1, in complex with dihydropyrrolopyrazol-6-one derivate 1 To Be Published
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2AIN
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8AE3
| Cryo-EM structure of full-length human immunoglobulin M - F(ab')2 conformation 4 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, IgM C2-domain from mouse, ... | Authors: | Chen, Q, Rosenthal, P, Tolar, P. | Deposit date: | 2022-07-12 | Release date: | 2022-10-26 | Last modified: | 2022-11-09 | Method: | ELECTRON MICROSCOPY (6.8 Å) | Cite: | Cryomicroscopy reveals the structural basis for a flexible hinge motion in the immunoglobulin M pentamer. Nat Commun, 13, 2022
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8AE0
| Cryo-EM structure of full-length human immunoglobulin M - F(ab')2 conformation 3 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, IgM C2-domain from mouse, ... | Authors: | Chen, Q, Rosenthal, P, Tolar, P. | Deposit date: | 2022-07-12 | Release date: | 2022-10-26 | Last modified: | 2022-11-09 | Method: | ELECTRON MICROSCOPY (7.1 Å) | Cite: | Cryomicroscopy reveals the structural basis for a flexible hinge motion in the immunoglobulin M pentamer. Nat Commun, 13, 2022
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8ADZ
| Cryo-EM structure of full-length human immunoglobulin M - F(ab')2 conformation 2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, IgM C2-domain from mouse, ... | Authors: | Chen, Q, Rosenthal, P, Tolar, P. | Deposit date: | 2022-07-12 | Release date: | 2022-10-26 | Last modified: | 2022-11-09 | Method: | ELECTRON MICROSCOPY (6.7 Å) | Cite: | Cryomicroscopy reveals the structural basis for a flexible hinge motion in the immunoglobulin M pentamer. Nat Commun, 13, 2022
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8ADY
| Cryo-EM structure of full-length human immunoglobulin M - F(ab')2 conformation 1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, IgM C2-domain from mouse, ... | Authors: | Chen, Q, Rosenthal, P, Tolar, P. | Deposit date: | 2022-07-12 | Release date: | 2022-10-26 | Last modified: | 2022-11-09 | Method: | ELECTRON MICROSCOPY (5.2 Å) | Cite: | Cryomicroscopy reveals the structural basis for a flexible hinge motion in the immunoglobulin M pentamer. Nat Commun, 13, 2022
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