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PDB: 139 results
4LS0
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BU of 4ls0 by Molmil
Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH01B0033
Descriptor: 2-{(E)-[2-(4-phenyl-1,3-thiazol-2-yl)hydrazinylidene]methyl}benzaldehyde, Dihydroorotate dehydrogenase (quinone), mitochondrial, ...
Authors:Zhu, L, Li, H, Ren, X, Zhu, J.
Deposit date:2013-07-21
Release date:2014-07-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DHO1B0033
To be Published
4LS2
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BU of 4ls2 by Molmil
Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A313
Descriptor: 2-[(E)-{2-[4-(3-methoxyphenyl)-1,3-thiazol-2-yl]hydrazinylidene}methyl]benzoic acid, ACETATE ION, Dihydroorotate dehydrogenase (quinone), ...
Authors:Zhu, L, Li, H, Ren, X, Zhu, J.
Deposit date:2013-07-21
Release date:2014-07-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A313
To be Published
1DDP
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BU of 1ddp by Molmil
Solution structure of a CISPLATIN-INDUCED [CATAGCTATG]2 Interstrand cross-link
Descriptor: Cisplatin, DNA (5'-D(*CP*AP*TP*AP*GP*CP*TP*AP*TP*G)-3')
Authors:Zhu, L, Huang, H, Reid, B.R, Drobny, G.P, Hopkins, P.B.
Deposit date:1995-10-26
Release date:1996-03-08
Last modified:2024-03-13
Method:SOLUTION NMR
Cite:Solution structure of a cisplatin-induced DNA interstrand cross-link.
Science, 270, 1995
3B9L
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BU of 3b9l by Molmil
Human serum albumin complexed with myristate and AZT
Descriptor: 3'-azido-3'-deoxythymidine, MYRISTIC ACID, Serum albumin
Authors:Zhu, L, Yang, F, Chen, L, Meehan, E.J, Huang, M.
Deposit date:2007-11-05
Release date:2008-05-27
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A new drug binding subsite on human serum albumin and drug-drug interaction studied by X-ray crystallography
J.Struct.Biol., 162, 2008
3B9M
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BU of 3b9m by Molmil
Human serum albumin complexed with myristate, 3'-azido-3'-deoxythymidine (AZT) and salicylic acid
Descriptor: 2-HYDROXYBENZOIC ACID, 3'-azido-3'-deoxythymidine, MYRISTIC ACID, ...
Authors:Zhu, L, Yang, F, Chen, L, Meehan, E.J, Huang, M.
Deposit date:2007-11-05
Release date:2008-05-27
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A new drug binding subsite on human serum albumin and drug-drug interaction studied by X-ray crystallography
J.Struct.Biol., 162, 2008
6KU8
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BU of 6ku8 by Molmil
structure of HRV-C 3C protein with rupintrivir
Descriptor: 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER, Genome polyprotein
Authors:Zhu, L, Yuan, S.
Deposit date:2019-08-31
Release date:2020-03-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structure of the HRV-C 3C-Rupintrivir Complex Provides New Insights for Inhibitor Design.
Virol Sin, 35, 2020
6KU7
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BU of 6ku7 by Molmil
structure of HRV-C 3C protein
Descriptor: Genome polyprotein
Authors:Zhu, L, Yuan, S.
Deposit date:2019-08-31
Release date:2020-03-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structure of the HRV-C 3C-Rupintrivir Complex Provides New Insights for Inhibitor Design.
Virol Sin, 35, 2020
1ZHU
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BU of 1zhu by Molmil
DNA (5'-D(*CP*AP*AP*TP*GP*CP*AP*AP*TP*G)-3'), NMR, 10 STRUCTURES
Descriptor: DNA (5'-D(*CP*AP*AP*TP*GP*CP*AP*AP*TP*G)-3')
Authors:Zhu, L, Chou, S.-H, Xu, J, Reid, B.R.
Deposit date:1996-01-24
Release date:1996-07-11
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure of a single-cytidine hairpin loop formed by the DNA triplet GCA.
Nat.Struct.Biol., 2, 1995
1XUE
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BU of 1xue by Molmil
STRUCTURE OF GTGGAATGCAATGGAAC HAIRPIN, NMR, 10 STRUCTURES
Descriptor: DNA (5'-D(*GP*TP*GP*GP*AP*AP*TP*GP*CP*AP*AP*TP*GP*GP*AP*AP*C)-3')
Authors:Zhu, L, Chou, S.-H, Reid, B.R.
Deposit date:1996-08-26
Release date:1997-03-12
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:A single G-to-C change causes human centromere TGGAA repeats to fold back into hairpins.
Proc.Natl.Acad.Sci.USA, 93, 1996
4RR4
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BU of 4rr4 by Molmil
Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A367
Descriptor: 2-chloro-N-[3-(4-{[(2Z)-2-cyano-3-cyclopropyl-3-hydroxyprop-2-enoyl]amino}phenoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxamide, Dihydroorotate dehydrogenase (quinone), mitochondrial, ...
Authors:Zhu, L, Ren, X, Zhu, J, Li, H.
Deposit date:2014-11-06
Release date:2015-11-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A367
TO BE PUBLISHED
4RKA
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BU of 4rka by Molmil
Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A347
Descriptor: 2-{[5-(naphthalen-1-ylmethyl)-4-oxo-4H-1lambda~4~,3-thiazol-2-yl]amino}benzoic acid, Dihydroorotate dehydrogenase (quinone), mitochondrial, ...
Authors:Zhu, L, Ren, X, Zhu, J, Li, H.
Deposit date:2014-10-12
Release date:2015-11-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A347
TO BE PUBLISHED
4RLI
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BU of 4rli by Molmil
Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A048
Descriptor: Dihydroorotate dehydrogenase (quinone), mitochondrial, FLAVIN MONONUCLEOTIDE, ...
Authors:Zhu, L, Ren, X, Zhu, J, Li, H.
Deposit date:2014-10-17
Release date:2015-11-04
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A048
TO BE PUBLISHED
4RK8
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BU of 4rk8 by Molmil
Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A356
Descriptor: 5-fluoro-2-{[(5Z)-5-(naphthalen-1-ylmethylidene)-4-oxo-4,5-dihydro-1,3-thiazol-2-yl]amino}benzoic acid, Dihydroorotate dehydrogenase (quinone), mitochondrial, ...
Authors:Zhu, L, Ren, X, Zhu, J, Li, H.
Deposit date:2014-10-12
Release date:2015-11-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A356
TO BE PUBLISHED
1LPV
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BU of 1lpv by Molmil
DROSOPHILA MELANOGASTER DOUBLESEX (DSX), NMR, 18 STRUCTURES
Descriptor: Doublesex protein, ZINC ION
Authors:Zhu, L, Wilken, J, Phillips, N, Narendra, U, Chan, G, Stratton, S, Kent, S, Weiss, M.A.
Deposit date:2002-05-08
Release date:2002-10-02
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Sexual dimorphism in diverse metazoans is regulated by a novel class of intertwined zinc fingers.
Genes Dev., 14, 2000
8A2G
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BU of 8a2g by Molmil
Crystal structure of Sebokelevirus 2A2 protein
Descriptor: 1,2-ETHANEDIOL, 2A2 protein, TETRAETHYLENE GLYCOL
Authors:Zhu, L, Von Castelmur, E, Whang, X, Ren, J, Fry, E, Perrakis, A, Stuart, D.I.
Deposit date:2022-06-03
Release date:2023-06-14
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Structural plasticity of 2A proteins in the Parechovirus family
to be published
104D
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BU of 104d by Molmil
DNA DUPLEXES FLANKED BY HYBRID DUPLEXES: THE SOLUTION STRUCTURE OF CHIMERIC JUNCTIONS IN
Descriptor: DNA/RNA (5'-R(*CP*GP*CP*G)-D(P*TP*AP*TP*AP*CP*GP*CP*G)-3')
Authors:Zhu, L, Salazar, M, Reid, B.R.
Deposit date:1994-12-16
Release date:1995-03-31
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:DNA duplexes flanked by hybrid duplexes: the solution structure of chimeric junctions in [r(cgcg)d(TATACGCG)]2.
Biochemistry, 34, 1995
5EGG
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BU of 5egg by Molmil
Crystal structure of human ubiquitin-conjugating enzyme UBCH5C
Descriptor: Ubiquitin-conjugating enzyme E2 D3
Authors:Zhu, L, Li, H, Wu, F, Zhu, J.
Deposit date:2015-10-27
Release date:2016-11-02
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Structural analysis of recombinant human ubiquitin-conjugating enzyme UbcH5c
Acta Pharm Sin B, 7, 2017
3JB4
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BU of 3jb4 by Molmil
Structure of Ljungan virus: insight into picornavirus packaging
Descriptor: VP0, VP1, VP3
Authors:Zhu, L, Wang, X.X, Ren, J.S, Porta, C, Wenham, H, Ekstrom, J.-O, Panjwani, A, Knowles, N.J, Kotecha, A, Siebert, A, Lindberg, M, Fry, E.E, Rao, Z.H, Tuthill, T.J, Stuart, D.I.
Deposit date:2015-07-21
Release date:2015-10-21
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure of Ljungan virus provides insight into genome packaging of this picornavirus.
Nat Commun, 6, 2015
3SND
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BU of 3snd by Molmil
Crystal structure of SARS coronavirus main protease complexed with Ac-ESTLQ-H (cocrystallization)
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, 3C-like proteinase, Peptide aldehyde inhibitor Ac-ESTLQ-H
Authors:Zhu, L, Hilgenfeld, R.
Deposit date:2011-06-29
Release date:2011-09-07
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Peptide aldehyde inhibitors challenge the substrate specificity of the SARS-coronavirus main protease.
Antiviral Res., 92, 2011
4LS1
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BU of 4ls1 by Molmil
Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A312
Descriptor: 2-[(E)-{2-[4-(2-chlorophenyl)-1,3-thiazol-2-yl]hydrazinylidene}methyl]benzoic acid, ACETATE ION, Dihydroorotate dehydrogenase (quinone), ...
Authors:Zhu, L, Li, H, Ren, X, Zhu, J.
Deposit date:2013-07-21
Release date:2014-07-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A312
To be Published
4JTS
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BU of 4jts by Molmil
Crystal structure of human dihydroorotate dehydrogenase (DHODH) with 072
Descriptor: 4-methyl-N-(naphthalen-2-yl)-1,3-thiazole-5-carboxamide, ACETATE ION, Dihydroorotate dehydrogenase (quinone), ...
Authors:Zhu, L, Zhu, J, Ren, X, Li, H.
Deposit date:2013-03-24
Release date:2014-03-26
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.206 Å)
Cite:Crystal structure of human dihydroorotate dehydrogenase (DHODH) with 057
To be Published
4JGD
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BU of 4jgd by Molmil
Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A016
Descriptor: 1-[4-methyl-2-(naphthalen-2-ylamino)-1,3-thiazol-5-yl]ethanone, Dihydroorotate dehydrogenase (quinone), mitochondrial, ...
Authors:Zhu, L, Zhu, J, Ren, X, Li, H.
Deposit date:2013-03-01
Release date:2014-03-05
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A016
TO BE PUBLISHED
4JTT
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BU of 4jtt by Molmil
Crystal structure of human dihydroorotate dehydrogenase (DHODH) with 066
Descriptor: 2,4-dimethyl-N-(naphthalen-2-yl)-1,3-thiazole-5-carboxamide, ACETATE ION, Dihydroorotate dehydrogenase (quinone), ...
Authors:Zhu, L, Li, H, Zhu, J, Ren, X.
Deposit date:2013-03-24
Release date:2014-03-26
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of human dihydroorotate dehydrogenase (DHODH) with 057
TO BE PUBLISHED
4JTU
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BU of 4jtu by Molmil
Crystal structure of human dihydroorotate dehydrogenase (DHODH) with brequinar analogue
Descriptor: 6-bromo-2-{4-[(2R)-butan-2-yl]phenyl}-3-methylquinoline-4-carboxylic acid, Dihydroorotate dehydrogenase (quinone), mitochondrial, ...
Authors:Zhu, L, Zhu, J, Ren, X, Li, H.
Deposit date:2013-03-24
Release date:2014-03-26
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of human dihydroorotate dehydrogenase (DHODH) with 057
To be Published
4JS3
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BU of 4js3 by Molmil
Crystal structure of human dihydroorotate dehydrogenase (DHODH) with 057
Descriptor: 2-chloro-4-methyl-N-(naphthalen-2-yl)-1,3-thiazole-5-carboxamide, ACETIC ACID, Dihydroorotate dehydrogenase (quinone), ...
Authors:Zhu, L, Li, H, Zhu, J, Ren, X.
Deposit date:2013-03-22
Release date:2014-03-26
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of human dihydroorotate dehydrogenase (DHODH) with 057
TO BE PUBLISHED

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