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PDB: 423 件

2HZ6
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The crystal structure of human IRE1-alpha luminal domain
分子名称: Endoplasmic reticulum to nucleus signalling 1 isoform 1 variant
著者Kaufman, R.J, Xu, Z, Zhou, J.
登録日2006-08-08
公開日2006-08-29
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献The crystal structure of human IRE1 luminal domain reveals a conserved dimerization interface required for activation of the unfolded protein response.
Proc.Natl.Acad.Sci.Usa, 103, 2006
5YAO
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The complex structure of SZ529 and expoxid
分子名称: (1R,5S)-6-oxabicyclo[3.1.0]hexane, Limonene-1,2-epoxide hydrolase, SODIUM ION
著者Lian, W, Sun, Z.T, Zhou, J.H, Reetz, M.T.
登録日2017-09-01
公開日2018-06-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.611 Å)
主引用文献Structural and Computational Insight into the Catalytic Mechanism of Limonene Epoxide Hydrolase Mutants in Stereoselective Transformations
J. Am. Chem. Soc., 140, 2018
3KCC
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Crystal structure of D138L mutant of Catabolite Gene Activator Protein
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Catabolite gene activator
著者Tao, W.B, Gao, Z.Q, Zhou, J.H, Dong, Y.H, Yu, S.N.
登録日2009-10-21
公開日2009-11-17
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献The 1.6A resolution structure of activated D138L mutant of catabolite gene activator protein with two cAMP bound in each monomer
Int.J.Biol.Macromol., 48, 2011
3H5W
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Crystal structure of the GluR2-ATD in space group P212121 without solvent
分子名称: Glutamate receptor 2
著者Jin, R, Singh, S.K, Gu, S, Furukawa, H, Sobolevsky, A, Zhou, J, Jin, Y, Gouaux, E.
登録日2009-04-22
公開日2009-06-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.686 Å)
主引用文献Crystal structure and association behaviour of the GluR2 amino-terminal domain.
Embo J., 28, 2009
3H5V
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Crystal structure of the GluR2-ATD
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2
著者Jin, R, Singh, S.K, Gu, S, Furukawa, H, Sobolevsky, A, Zhou, J, Jin, Y, Gouaux, E.
登録日2009-04-22
公開日2009-06-09
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Crystal structure and association behaviour of the GluR2 amino-terminal domain.
Embo J., 28, 2009
4MYS
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1.4 Angstrom Crystal Structure of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase with SHCHC and Pyruvate
分子名称: 2-(3-CARBOXYPROPIONYL)-6-HYDROXY-CYCLOHEXA-2,4-DIENE CARBOXYLIC ACID, 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase, GLYCEROL, ...
著者Sun, Y, Yin, S, Feng, Y, Li, J, Zhou, J, Liu, C, Zhu, G, Guo, Z.
登録日2013-09-28
公開日2014-04-23
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.423 Å)
主引用文献Molecular basis of the general base catalysis of an alpha / beta-hydrolase catalytic triad.
J.Biol.Chem., 289, 2014
4INZ
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BU of 4inz by Molmil
The crystal structure of M145A mutant of an epoxide hydrolase from Bacillus megaterium
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Soluble epoxide hydrolase
著者Kong, X.D, Zhou, J.H, Xu, J.H.
登録日2013-01-07
公開日2014-02-12
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Engineering of an epoxide hydrolase for efficient bioresolution of bulky pharmaco substrates.
Proc.Natl.Acad.Sci.USA, 111, 2014
4IO0
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Crystal structure of F128A mutant of an epoxide hydrolase from Bacillus megaterium complexed with its product (R)-3-[1]naphthyloxy-propane-1,2-diol
分子名称: (2R)-3-(naphthalen-1-yloxy)propane-1,2-diol, SULFATE ION, Soluble epoxide hydrolase
著者Kong, X.D, Zhou, J.H, Xu, J.H.
登録日2013-01-07
公開日2014-02-12
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Engineering of an epoxide hydrolase for efficient bioresolution of bulky pharmaco substrates.
Proc.Natl.Acad.Sci.USA, 111, 2014
4OB8
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Crystal structure of a novel thermostable esterase from Pseudomonas putida ECU1011
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Alpha/beta hydrolase fold-3 domain protein, DI(HYDROXYETHYL)ETHER
著者Dou, S, Kong, X.D, Ma, B.D, Xu, J.H, Zhou, J.H.
登録日2014-01-07
公開日2014-07-23
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.801 Å)
主引用文献Crystal structures of Pseudomonas putida esterase reveal the functional role of residues 187 and 287 in substrate binding and chiral recognition
Biochem.Biophys.Res.Commun., 446, 2014
5CK6
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Crystal structure of SZ348 in complex with cyclopentene oxide
分子名称: (1R,5S)-6-oxabicyclo[3.1.0]hexane, Limonene-1,2-epoxide hydrolase, NICKEL (II) ION, ...
著者Wu, L, Sun, Z.T, Reetz, M.T, Zhou, J.H.
登録日2015-07-15
公開日2016-07-20
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of SZ348 in complex with cyclopentene oxide
To Be Published
5CLK
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Crystal structure of SZ348 in complex with S,S-cyclohexanediol
分子名称: (1S,2S)-cyclohexane-1,2-diol, CHLORIDE ION, Limonene-1,2-epoxide hydrolase, ...
著者Wu, L, Sun, Z.T, Reetz, M.T, Zhou, J.H.
登録日2015-07-16
公開日2016-07-20
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.701 Å)
主引用文献Crystal structure of SZ348 in complex with S,S-cyclohexanediol
To Be Published
5HSJ
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Structure of tyrosine decarboxylase complex with PLP at 1.9 Angstroms resolution
分子名称: PYRIDOXAL-5'-PHOSPHATE, Putative decarboxylase
著者Ni, Y, Zhou, J, Zhu, H, Zhang, K.
登録日2016-01-25
公開日2016-09-14
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of tyrosine decarboxylase and identification of key residues involved in conformational swing and substrate binding
Sci Rep, 6, 2016
5CF1
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Crystal Structure of the M32V/M78V/I80V/L114F mutant of LEH
分子名称: Limonene-1,2-epoxide hydrolase
著者Wu, L, Sun, Z.T, Reetz, M.T, Zhou, J.H.
登録日2015-07-08
公開日2016-07-13
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.242 Å)
主引用文献Crystal Structure of the M32V/M78V/I80V/L114F mutant of LEH
To Be Published
3R4S
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BU of 3r4s by Molmil
Cell entry of botulinum neurotoxin type C is dependent upon interaction with two ganglioside molecules
分子名称: Botulinum neurotoxin type C1, N-acetyl-alpha-neuraminic acid, N-acetyl-beta-neuraminic acid
著者Strotmeier, J, Gu, S, Jutzi, S, Mahrhold, S, Zhou, J, Pich, A, Bigalke, H, Rummel, A, Jin, R, Binz, T.
登録日2011-03-17
公開日2011-06-08
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献The biological activity of botulinum neurotoxin type C is dependent upon novel types of ganglioside binding sites.
Mol.Microbiol., 81, 2011
3R4U
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Cell entry of botulinum neurotoxin type C is dependent upon interaction with two ganglioside molecules
分子名称: Botulinum neurotoxin type C1
著者Strotmeier, J, Gu, S, Jutzi, S, Mahrhold, S, Zhou, J, Pich, A, Bigalke, H, Rummel, A, Jin, R, Binz, T.
登録日2011-03-17
公開日2011-06-08
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The biological activity of botulinum neurotoxin type C is dependent upon novel types of ganglioside binding sites.
Mol.Microbiol., 81, 2011
7CMH
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BU of 7cmh by Molmil
The LAT2-4F2hc complex in complex with tryptophan
分子名称: 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4F2 cell-surface antigen heavy chain, ...
著者Yan, R.H, Zhou, J.Y, Li, Y.N, Lei, J.L, Zhou, Q.
登録日2020-07-27
公開日2020-12-23
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural insight into the substrate recognition and transport mechanism of the human LAT2-4F2hc complex.
Cell Discov, 6, 2020
4HPH
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BU of 4hph by Molmil
The crystal structure of isomaltulose synthase mutant E295Q from Erwinia rhapontici NX5 in complex with its natural substrate sucrose
分子名称: CALCIUM ION, GLYCEROL, Sucrose isomerase, ...
著者Xu, Z, Li, S, Xu, H, Zhou, J.
登録日2012-10-23
公開日2013-10-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The Structural Basis of Erwinia rhapontici Isomaltulose Synthase
Plos One, 8, 2013
4MYD
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BU of 4myd by Molmil
1.37 Angstrom Crystal Structure of E. Coli 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase (MenH) in complex with SHCHC
分子名称: 2-(3-CARBOXYPROPIONYL)-6-HYDROXY-CYCLOHEXA-2,4-DIENE CARBOXYLIC ACID, 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase
著者Sun, Y, Yin, S, Feng, Y, Li, J, Zhou, J, Liu, C, Zhu, G, Guo, Z.
登録日2013-09-27
公開日2014-04-23
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.374 Å)
主引用文献Molecular basis of the general base catalysis of an alpha / beta-hydrolase catalytic triad.
J.Biol.Chem., 289, 2014
4HOW
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BU of 4how by Molmil
The crystal structure of isomaltulose synthase from Erwinia rhapontici NX5
分子名称: CALCIUM ION, GLYCEROL, Sucrose isomerase
著者Xu, Z, Li, S, Xu, H, Zhou, J.
登録日2012-10-22
公開日2013-10-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The Structural Basis of Erwinia rhapontici Isomaltulose Synthase
Plos One, 8, 2013
4MXD
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BU of 4mxd by Molmil
1.45 angstronm crystal structure of E.coli 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase (MenH)
分子名称: 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Sun, Y, Yin, S, Feng, Y, Li, J, Zhou, J, Liu, C, Zhu, G, Guo, Z.
登録日2013-09-26
公開日2014-04-23
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Molecular basis of the general base catalysis of an alpha / beta-hydrolase catalytic triad.
J.Biol.Chem., 289, 2014
4HOZ
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The crystal structure of isomaltulose synthase mutant D241A from Erwinia rhapontici NX5 in complex with D-glucose
分子名称: CALCIUM ION, GLYCEROL, Sucrose isomerase, ...
著者Xu, Z, Li, S, Xu, H, Zhou, J.
登録日2012-10-23
公開日2013-10-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Structural Basis of Erwinia rhapontici Isomaltulose Synthase
Plos One, 8, 2013
7VOB
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The crystal structure of a Radical SAM Enzyme BlsE involved in the Biosynthesis of Blasticidin S
分子名称: CHLORIDE ION, Cytosylglucuronate decarboxylase, GLYCEROL, ...
著者Hou, X.L, Zhou, J.H.
登録日2021-10-13
公開日2022-05-04
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.092241 Å)
主引用文献Radical S -Adenosyl Methionine Enzyme BlsE Catalyzes a Radical-Mediated 1,2-Diol Dehydration during the Biosynthesis of Blasticidin S.
J.Am.Chem.Soc., 144, 2022
4OB6
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Complex structure of esterase rPPE S159A/W187H and substrate (S)-Ac-CPA
分子名称: (2S)-(acetyloxy)(2-chlorophenyl)ethanoic acid, Alpha/beta hydrolase fold-3 domain protein
著者Dou, S, Kong, X.D, Ma, B.D, Chen, Q, Zhou, J.H, Xu, J.H.
登録日2014-01-07
公開日2014-07-23
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structures of Pseudomonas putida esterase reveal the functional role of residues 187 and 287 in substrate binding and chiral recognition
Biochem.Biophys.Res.Commun., 446, 2014
4OU4
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Crystal structure of esterase rPPE mutant S159A complexed with (S)-Ac-CPA
分子名称: (2S)-(acetyloxy)(2-chlorophenyl)ethanoic acid, Alpha/beta hydrolase fold-3 domain protein
著者Dou, S, Kong, X.D, Ma, B.D, Xu, J.H, Zhou, J.H.
登録日2014-02-15
公開日2014-07-30
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structures of Pseudomonas putida esterase reveal the functional role of residues 187 and 287 in substrate binding and chiral recognition
Biochem.Biophys.Res.Commun., 446, 2014
4OB7
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Crystal structure of esterase rPPE mutant W187H
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Alpha/beta hydrolase fold-3 domain protein, DI(HYDROXYETHYL)ETHER
著者Dou, S, Kong, X.D, Ma, B.D, Xu, J.H, Zhou, J.H.
登録日2014-01-07
公開日2014-07-23
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal structures of Pseudomonas putida esterase reveal the functional role of residues 187 and 287 in substrate binding and chiral recognition
Biochem.Biophys.Res.Commun., 446, 2014

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