3FRQ
 
 | | Structure of the macrolide biosensor protein, MphR(A), with erythromcyin | | Descriptor: | CHLORIDE ION, ERYTHROMYCIN A, GLYCEROL, ... | | Authors: | Zheng, J, Sagar, V, Smolinsky, A, Bourke, C, LaRonde-LeBlanc, N, Cropp, T.A. | | Deposit date: | 2009-01-08 | | Release date: | 2009-03-24 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.76 Å) | | Cite: | Structure and function of the macrolide biosensor protein, MphR(A), with and without erythromycin
J.Mol.Biol., 387, 2009
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1CMK
 | | CRYSTAL STRUCTURES OF THE MYRISTYLATED CATALYTIC SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE REVEAL OPEN AND CLOSED CONFORMATIONS | | Descriptor: | IODIDE ION, MYRISTIC ACID, cAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT, ... | | Authors: | Zheng, J, Knighton, D.R, Xuong, N.-H, Taylor, S.S, Sowadski, J.M, Ten Eyck, L.F. | | Deposit date: | 1993-11-18 | | Release date: | 1994-05-31 | | Last modified: | 2024-12-25 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Crystal structures of the myristylated catalytic subunit of cAMP-dependent protein kinase reveal open and closed conformations.
Protein Sci., 2, 1993
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1ATP
 | | 2.2 angstrom refined crystal structure of the catalytic subunit of cAMP-dependent protein kinase complexed with MNATP and a peptide inhibitor | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, PEPTIDE INHIBITOR PKI(5-24), ... | | Authors: | Zheng, J, Trafny, E.A, Knighton, D.R, Xuong, N.-H, Taylor, S.S, Teneyck, L.F, Sowadski, J.M. | | Deposit date: | 1993-01-08 | | Release date: | 1993-04-15 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | 2.2 A refined crystal structure of the catalytic subunit of cAMP-dependent protein kinase complexed with MnATP and a peptide inhibitor.
Acta Crystallogr.,Sect.D, 49, 1993
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4DIF
 | | Structure of A1-type ketoreductase | | Descriptor: | AmphB, GLYCEROL, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | Authors: | Zheng, J, Keatinge-Clay, A.T. | | Deposit date: | 2012-01-30 | | Release date: | 2013-02-13 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.521 Å) | | Cite: | Structure and mutagenesis of A2-type ketoreductase from modular polyketide synthase reveals insights into stereospecificity
To be Published
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4P0U
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8YLN
 | | The structure of DSR2-Tail tube complex | | Descriptor: | Bacillus phage SPR Tube protein, SIR2-like domain-containing protein | | Authors: | Zheng, J, Yang, X. | | Deposit date: | 2024-03-06 | | Release date: | 2024-08-14 | | Method: | ELECTRON MICROSCOPY (3.53 Å) | | Cite: | Structural insights into autoinhibition and activation of defense-associated sirtuin protein.
Int.J.Biol.Macromol., 277, 2024
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8Z18
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8YLT
 | | The structure of DSR2 and NAD+ complex | | Descriptor: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SIR2-like domain-containing protein | | Authors: | Zheng, J, Yang, X. | | Deposit date: | 2024-03-06 | | Release date: | 2024-08-14 | | Method: | ELECTRON MICROSCOPY (3.09 Å) | | Cite: | Structural insights into autoinhibition and activation of defense-associated sirtuin protein.
Int.J.Biol.Macromol., 277, 2024
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8YKF
 | | The DSR2-DSAD1 complex with DSAD1 on the opposite sides | | Descriptor: | DSAD1, SIR2-like domain-containing protein | | Authors: | Zheng, J, Yang, X. | | Deposit date: | 2024-03-05 | | Release date: | 2024-08-14 | | Last modified: | 2024-10-09 | | Method: | ELECTRON MICROSCOPY (3.35 Å) | | Cite: | Structural insights into autoinhibition and activation of defense-associated sirtuin protein.
Int.J.Biol.Macromol., 277, 2024
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4PT1
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5XDM
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5LVX
 | | Crystal structure of glucocerebrosidase with an inhibitory quinazoline modulator | | Descriptor: | 11-[(2~{R})-2-[(2-pyridin-3-ylquinazolin-4-yl)amino]-2,3-dihydro-1~{H}-inden-5-yl]undec-10-ynoic acid, 11-[(2~{S})-2-[(2-pyridin-3-ylquinazolin-4-yl)amino]-2,3-dihydro-1~{H}-inden-5-yl]undec-10-ynoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Zheng, J, Chen, L, Skinner, O.S, Lansbury, P, Skerlj, R, Mrosek, M, Heunisch, U, Krapp, S, Weigand, S, Charrow, J, Schwake, M, Kelleher, N.L, Silverman, R.B, Krainc, D. | | Deposit date: | 2016-09-14 | | Release date: | 2017-10-25 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | beta-Glucocerebrosidase Modulators Promote Dimerization of beta-Glucocerebrosidase and Reveal an Allosteric Binding Site.
J. Am. Chem. Soc., 140, 2018
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1U5W
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1ZYL
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8ZI5
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4XXB
 | | Crystal structure of human MDM2-RPL11 | | Descriptor: | 60S ribosomal protein L11, BETA-MERCAPTOETHANOL, E3 ubiquitin-protein ligase Mdm2, ... | | Authors: | Zheng, J, Chen, Z. | | Deposit date: | 2015-01-30 | | Release date: | 2015-08-12 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structure of human MDM2 complexed with RPL11 reveals the molecular basis of p53 activation
Genes Dev., 29, 2015
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1AWE
 | | HUMAN SOS1 PLECKSTRIN HOMOLOGY (PH) DOMAIN, NMR, 20 STRUCTURES | | Descriptor: | SOS1 | | Authors: | Zheng, J, Cowburn, D. | | Deposit date: | 1997-10-01 | | Release date: | 1998-02-25 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | The solution structure of the pleckstrin homology domain of human SOS1. A possible structural role for the sequential association of diffuse B cell lymphoma and pleckstrin homology domains.
J.Biol.Chem., 272, 1997
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8ZTR
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8ZIK
 | | Crystal structure of a beta-1,4-endoglucanase from Bispora sp. MEY-1 in complex with cellotetraose | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose, cellulase | | Authors: | Zheng, J, Luo, H.Y, Yao, B, Tian, J. | | Deposit date: | 2024-05-14 | | Release date: | 2025-05-21 | | Method: | X-RAY DIFFRACTION (1.87 Å) | | Cite: | Unraveling the Key Determinants of Substrate Promiscuity in Glycoside Hydrolase Family 5_5 Cellulases
To Be Published
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3G56
 | | Structure of the macrolide biosensor protein, MphR(A) | | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, Regulator of macrolide 2'-phosphotransferase I | | Authors: | Zheng, J, Sagar, V, Smolinsky, A, Bourke, C, LaRonde-LeBlanc, N, Cropp, T.A. | | Deposit date: | 2009-02-04 | | Release date: | 2009-03-03 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structure and function of the macrolide biosensor protein, MphR(A), with and without erythromycin
J.Mol.Biol., 387, 2009
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2QKA
 | | Structural and Kinetic Study of the Differences between Human and E.coli Manganese Superoxide Dismutases | | Descriptor: | MANGANESE (II) ION, Superoxide dismutase [Mn] | | Authors: | Zheng, J, Domsic, J.F, Cabelli, D, McKenna, R, Silverman, D.N. | | Deposit date: | 2007-07-10 | | Release date: | 2008-07-29 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural and kinetic study of differences between human and Escherichia coli manganese superoxide dismutases.
Biochemistry, 46, 2007
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2QKC
 | | Structural and Kinetic Study of the Differences between Human and E.coli Manganese Superoxide Dismutases | | Descriptor: | MANGANESE (II) ION, Superoxide dismutase [Mn] | | Authors: | Zheng, J, Domsic, J.F, Cabelli, D, McKenna, R, Silverman, D.N. | | Deposit date: | 2007-07-10 | | Release date: | 2008-07-29 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural and kinetic study of differences between human and Escherichia coli manganese superoxide dismutases.
Biochemistry, 46, 2007
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8ZAB
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8ZAA
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8ZA9
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