6GV9
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![BU of 6gv9 by Molmil](/molmil-images/mine/6gv9) | Structure of the type IV pilus from enterohemorrhagic Escherichia coli (EHEC) | 分子名称: | Prepilin peptidase-dependent protein D | 著者 | Bardiaux, B, Amorim, G.C, Luna-Rico, A, Zheng, W, Guilvout, I, Jollivet, C, Nilges, M, Egelman, E, Francetic, O, Izadi-Pruneyre, N. | 登録日 | 2018-06-20 | 公開日 | 2019-05-15 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (8 Å) | 主引用文献 | Structure and Assembly of the Enterohemorrhagic Escherichia coli Type 4 Pilus. Structure, 27, 2019
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4FMU
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![BU of 4fmu by Molmil](/molmil-images/mine/4fmu) | Crystal structure of Methyltransferase domain of human SET domain-containing protein 2 Compound: Pr-SNF | 分子名称: | (2S,5S)-2-amino-6-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]-5-(propylamino)hexanoic acid, Histone-lysine N-methyltransferase SETD2, UNKNOWN ATOM OR ION, ... | 著者 | Dong, A, Zeng, H, Ibanez, G, Zheng, W, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Min, J, Luo, M, Wu, H, Structural Genomics Consortium (SGC) | 登録日 | 2012-06-18 | 公開日 | 2012-09-05 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Sinefungin Derivatives as Inhibitors and Structure Probes of Protein Lysine Methyltransferase SETD2. J.Am.Chem.Soc., 134, 2012
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4IKP
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![BU of 4ikp by Molmil](/molmil-images/mine/4ikp) | Crystal structure of coactivator-associated arginine methyltransferase 1 with methylenesinefungin | 分子名称: | (2S,5S)-2,6-diamino-5-{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl}hexanoic acid, GLYCEROL, Histone-arginine methyltransferase CARM1, ... | 著者 | Dong, A, Dombrovski, L, He, H, Ibanez, G, Wernimont, A, Zheng, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Min, J, Luo, M, Wu, H, Structural Genomics Consortium (SGC) | 登録日 | 2012-12-27 | 公開日 | 2013-02-13 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A chemical probe of CARM1 alters epigenetic plasticity against breast cancer cell invasion. Elife, 8, 2019
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7VFJ
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![BU of 7vfj by Molmil](/molmil-images/mine/7vfj) | Cytochrome c-type biogenesis protein CcmABCD | 分子名称: | Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein B, Heme exporter protein C, ... | 著者 | Zhu, J.P, Zhang, K, Li, J, Zheng, W, Gu, M. | 登録日 | 2021-09-13 | 公開日 | 2022-11-09 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.98 Å) | 主引用文献 | Structures of the CcmABCD heme release complex at multiple states. Nat Commun, 13, 2022
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7VFP
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![BU of 7vfp by Molmil](/molmil-images/mine/7vfp) | Cytochrome c-type biogenesis protein CcmABCD from E. coli in complex with heme and single ATP | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein B, ... | 著者 | Li, J, Zheng, W, Gu, M, Zhang, K, Zhu, J.P. | 登録日 | 2021-09-13 | 公開日 | 2022-11-09 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (4.03 Å) | 主引用文献 | Structures of the CcmABCD heme release complex at multiple states. Nat Commun, 13, 2022
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3L1N
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![BU of 3l1n by Molmil](/molmil-images/mine/3l1n) | Crystal structure of Mp1p ligand binding domain 2 complexd with palmitic acid | 分子名称: | Cell wall antigen, PALMITIC ACID | 著者 | Liao, S, Tung, E.T, Zheng, W, Chong, K, Xu, Y, Bartlam, M, Rao, Z, Yuen, K.Y. | 登録日 | 2009-12-14 | 公開日 | 2010-01-05 | 最終更新日 | 2021-11-10 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Crystal structure of the Mp1p ligand binding domain 2 reveals its function as a fatty acid-binding protein. J.Biol.Chem., 285, 2010
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2CB5
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![BU of 2cb5 by Molmil](/molmil-images/mine/2cb5) | HUMAN BLEOMYCIN HYDROLASE, C73S/DELE455 MUTANT | 分子名称: | PROTEIN (BLEOMYCIN HYDROLASE) | 著者 | O'Farrell, P.A, Gonzalez, F, Zheng, W, Johnston, S.A, Joshua-Tor, L. | 登録日 | 1999-03-02 | 公開日 | 2000-03-06 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Crystal structure of human bleomycin hydrolase, a self-compartmentalizing cysteine protease. Structure Fold.Des., 7, 1999
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7C6Q
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![BU of 7c6q by Molmil](/molmil-images/mine/7c6q) | Novel natural PPARalpha agonist with a unique binding mode | 分子名称: | 13-methyl[1,3]benzodioxolo[5,6-c][1,3]dioxolo[4,5-i]phenanthridin-13-ium, LYS-ILE-LEU-HIS-ARG-LEU-LEU-GLN, Peroxisome proliferator-activated receptor alpha | 著者 | Tian, S.Y, Wang, R, Zheng, W.L, Li, Y. | 登録日 | 2020-05-22 | 公開日 | 2021-05-26 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.76 Å) | 主引用文献 | Structural Basis for PPARs Activation by The Dual PPAR alpha / gamma Agonist Sanguinarine: A Unique Mode of Ligand Recognition. Molecules, 26, 2021
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4DQM
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![BU of 4dqm by Molmil](/molmil-images/mine/4dqm) | Revealing a marine natural product as a novel agonist for retinoic acid receptors with a unique binding mode and antitumor activity | 分子名称: | (5S)-4-[(3E,7E)-4,8-dimethyl-10-(2,6,6-trimethylcyclohex-1-en-1-yl)deca-3,7-dien-1-yl]-5-hydroxyfuran-2(5H)-one, Nuclear receptor coactivator 1, Retinoic acid receptor alpha | 著者 | Wang, S, Wang, Z, Lin, S, Zheng, W, Wang, R, Jin, S, Chen, J, Jin, L, Li, Y. | 登録日 | 2012-02-16 | 公開日 | 2012-10-03 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Revealing a natural marine product as a novel agonist for retinoic acid receptors with a unique binding mode and inhibitory effects on cancer cells. Biochem.J., 446, 2012
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3GCB
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![BU of 3gcb by Molmil](/molmil-images/mine/3gcb) | GAL6 (YEAST BLEOMYCIN HYDROLASE) MUTANT C73A/DELTAK454 | 分子名称: | GAL6, GLYCEROL, SULFATE ION | 著者 | Joshua-Tor, L, Zheng, W, Johnston, S.A. | 登録日 | 1998-02-27 | 公開日 | 1998-10-21 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | The unusual active site of Gal6/bleomycin hydrolase can act as a carboxypeptidase, aminopeptidase, and peptide ligase. Cell(Cambridge,Mass.), 93, 1998
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7WB2
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![BU of 7wb2 by Molmil](/molmil-images/mine/7wb2) | Oxidase ChaP-D49L/Y109F mutant | 分子名称: | ChaP, FE (III) ION | 著者 | Zong, Y, Zheng, W, Wang, Y, Zhu, J, Tan, R. | 登録日 | 2021-12-15 | 公開日 | 2022-05-11 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Alteration of the Catalytic Reaction Trajectory of a Vicinal Oxygen Chelate Enzyme by Directed Evolution. Angew.Chem.Int.Ed.Engl., 61, 2022
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1A6R
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![BU of 1a6r by Molmil](/molmil-images/mine/1a6r) | GAL6 (YEAST BLEOMYCIN HYDROLASE) MUTANT C73A | 分子名称: | GAL6, SULFATE ION | 著者 | Joshua-Tor, L, Zheng, W, Johnston, S.A. | 登録日 | 1998-02-27 | 公開日 | 1998-10-21 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | The unusual active site of Gal6/bleomycin hydrolase can act as a carboxypeptidase, aminopeptidase, and peptide ligase. Cell(Cambridge,Mass.), 93, 1998
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3RBW
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![BU of 3rbw by Molmil](/molmil-images/mine/3rbw) | Crystal structure of Spire KIND domain | 分子名称: | Protein spire homolog 1 | 著者 | Vizcarra, C.L, Kreutz, B, Rodal, A.A, Toms, A.V, Lu, J, Zheng, W, Quinlan, M.E, Eck, M.J. | 登録日 | 2011-03-30 | 公開日 | 2011-07-06 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structure of the Spire KIND domain and insights into its interaction with Fmn-family formins Proc.Natl.Acad.Sci.USA, 2011
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7W5E
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![BU of 7w5e by Molmil](/molmil-images/mine/7w5e) | Oxidase ChaP D49L mutant | 分子名称: | ChaP, FE (III) ION | 著者 | Wang, Y, Zheng, W, Meng, Z, Jin, Y, Zhu, J, Tan, R. | 登録日 | 2021-11-30 | 公開日 | 2022-10-26 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Alteration of the Catalytic Reaction Trajectory of a Vicinal Oxygen Chelate Enzyme by Directed Evolution. Angew.Chem.Int.Ed.Engl., 61, 2022
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7WCC
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![BU of 7wcc by Molmil](/molmil-images/mine/7wcc) | Oxidase ChaP-D49L/Q91C mutant | 分子名称: | ChaP, FE (III) ION | 著者 | Sun, M.X, Zheng, W, Wang, Y.S, Zhu, J.P, Tan, R.X. | 登録日 | 2021-12-19 | 公開日 | 2023-05-24 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Oxidase ChaP-D49L/Q91C mutant To Be Published
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7C6P
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![BU of 7c6p by Molmil](/molmil-images/mine/7c6p) | Bromodomain-containing 4 BD2 in complex with 3',4',7,8- Tetrahydroxyflavonoid | 分子名称: | 2-[3,4-bis(oxidanyl)phenyl]-7,8-bis(oxidanyl)chromen-4-one, Bromodomain-containing protein 4 | 著者 | Li, J, Yu, K, Luo, Y, Zheng, W, Liang, W, Zhu, J. | 登録日 | 2020-05-22 | 公開日 | 2021-05-12 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | Discovery of the natural product 3',4',7,8-tetrahydroxyflavone as a novel and potent selective BRD4 bromodomain 2 inhibitor. J Enzyme Inhib Med Chem, 36, 2021
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