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PDB: 92 件
8JKM
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RN-1747 bound state of mTRPV4
分子名称: Transient receptor potential cation channel subfamily V member 4
著者Zhen, W.X, Yang, F.
登録日2023-06-01
公開日2023-12-13
実験手法ELECTRON MICROSCOPY (3.98 Å)
主引用文献Structural basis of ligand activation and inhibition in a mammalian TRPV4 ion channel.
Cell Discov, 9, 2023
8J1H
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BU of 8j1h by Molmil
Agonist1 and Ruthenium Red bound state of mTRPV4
分子名称: 8-fluoranyl-3-[4-(4-fluoranylphenoxy)phenyl]-2-(4-methylpiperazin-1-yl)quinazolin-4-one, Transient receptor potential cation channel subfamily V member 4
著者Zhen, W.X, Yang, F.
登録日2023-04-12
公開日2023-08-09
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.88 Å)
主引用文献Structural basis of ligand activation and inhibition in a mammalian TRPV4 ion channel.
Cell Discov, 9, 2023
8J1D
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Cryo-EM structure of apo state mTRPV4
分子名称: Transient receptor potential cation channel subfamily V member 4
著者Zhen, W.X, Yang, F.
登録日2023-04-12
公開日2023-08-09
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.59 Å)
主引用文献Structural basis of ligand activation and inhibition in a mammalian TRPV4 ion channel.
Cell Discov, 9, 2023
8J1F
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GSK101 bound state of mTRPV4
分子名称: N-[(2S)-1-{4-[N-(2,4-dichlorobenzene-1-sulfonyl)-L-seryl]piperazin-1-yl}-4-methyl-1-oxopentan-2-yl]-1-benzothiophene-2-carboxamide, Transient receptor potential cation channel subfamily V member 4
著者Zhen, W.X, Yang, F.
登録日2023-04-12
公開日2023-08-09
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.62 Å)
主引用文献Structural basis of ligand activation and inhibition in a mammalian TRPV4 ion channel.
Cell Discov, 9, 2023
8J1B
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BU of 8j1b by Molmil
GSK101 and Ruthenium Red bound state of mTRPV4
分子名称: N-[(2S)-1-{4-[N-(2,4-dichlorobenzene-1-sulfonyl)-L-seryl]piperazin-1-yl}-4-methyl-1-oxopentan-2-yl]-1-benzothiophene-2-carboxamide, Transient receptor potential cation channel subfamily V member 4, ruthenium(6+) azanide pentaamino(oxido)ruthenium (1/4/2)
著者Zhen, W.X, Yang, F.
登録日2023-04-12
公開日2023-08-09
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.72 Å)
主引用文献Structural basis of ligand activation and inhibition in a mammalian TRPV4 ion channel.
Cell Discov, 9, 2023
8YSA
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BU of 8ysa by Molmil
The co-crystal structure of SARS-CoV-2 Mpro in complex with compound H102
分子名称: 3C-like proteinase nsp5, BOC-TBG-PHE-ELL
著者Zheng, W.Y, Fu, L.F, Feng, Y, Han, P, Qi, J.X.
登録日2024-03-22
公開日2024-05-08
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Discovery, Biological Activity, and Structural Mechanism of a Potent Inhibitor of SARS-CoV-2 Main Protease
To Be Published
6OIF
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BU of 6oif by Molmil
Cryo-EM structure of human TorsinA filament
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Torsin-1A
著者Zheng, W, Demircioglu, F.E, Schwartz, T.U, Egelman, E.H.
登録日2019-04-09
公開日2019-07-24
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献The AAA + ATPase TorsinA polymerizes into hollow helical tubes with 8.5 subunits per turn.
Nat Commun, 10, 2019
6NRV
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Cryo-EM reconstruction of CFA/I pili
分子名称: CFA/I fimbrial subunit B
著者Zheng, W, Andersson, M, Bullitt, E, Egelman, E.H.
登録日2019-01-24
公開日2019-09-11
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Cryo-EM structure of the CFA/I pilus rod.
Iucrj, 6, 2019
7JSV
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BU of 7jsv by Molmil
Cryo-EM structure of conjugative pili from carbapenem-resistant Klebsiella pneumoniae
分子名称: 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, Pilin
著者Zheng, W, Pena, A, Frankel, G, Egelman, E.H.
登録日2020-08-16
公開日2020-09-02
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Cryoelectron-Microscopic Structure of the pKpQIL Conjugative Pili from Carbapenem-Resistant Klebsiella pneumoniae.
Structure, 28, 2020
5F1M
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Crystal structure of Serine/threonine phosphatase Stp1 from Staphylococcus aureus
分子名称: MANGANESE (II) ION, Phosphorylated protein phosphatase
著者Zheng, W.H, Wang, T, Li, Z.G.
登録日2015-11-30
公開日2016-08-24
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.322 Å)
主引用文献Structure-Based Identification of a Potent Inhibitor Targeting Stp1-Mediated Virulence Regulation in Staphylococcus aureus
Cell Chem Biol, 23, 2016
8IXE
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GMPCPP-Alpha1C/Beta2A-microtubule decorated with kinesin seam region
分子名称: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-1 heavy chain, ...
著者Zheng, W, Zhao, Q.Y, Diao, L, Bao, L, Cong, Y.
登録日2023-03-31
公開日2023-08-16
最終更新日2023-10-25
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Cryo-EM of alpha-tubulin isotype-containing microtubules revealed a contracted structure of alpha 4A/ beta 2A microtubules.
Acta Biochim.Biophys.Sin., 55, 2023
8IXB
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GMPCPP-Alpha1A/Beta2A-microtubule decorated with kinesin seam region
分子名称: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-1 heavy chain, ...
著者Zheng, W, Zhao, Q.Y, Diao, L, Bao, L, Cong, Y.
登録日2023-03-31
公開日2023-08-16
最終更新日2023-10-25
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Cryo-EM of alpha-tubulin isotype-containing microtubules revealed a contracted structure of alpha 4A/ beta 2A microtubules.
Acta Biochim.Biophys.Sin., 55, 2023
8IXG
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BU of 8ixg by Molmil
GMPCPP-Alpha4A/Beta2A-microtubule decorated with kinesin seam region
分子名称: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-1 heavy chain, ...
著者Zheng, W, Zhao, Q.Y, Diao, L, Bao, L, Cong, Y.
登録日2023-03-31
公開日2023-08-16
最終更新日2023-10-25
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Cryo-EM of alpha-tubulin isotype-containing microtubules revealed a contracted structure of alpha 4A/ beta 2A microtubules.
Acta Biochim.Biophys.Sin., 55, 2023
8IXA
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BU of 8ixa by Molmil
GMPCPP-Alpha1A/Beta2A-microtubule decorated with kinesin non-seam region
分子名称: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-1 heavy chain, ...
著者Zheng, W, Zhao, Q.Y, Diao, L, Bao, L, Cong, Y.
登録日2023-03-31
公開日2023-08-16
最終更新日2023-10-25
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Cryo-EM of alpha-tubulin isotype-containing microtubules revealed a contracted structure of alpha 4A/ beta 2A microtubules.
Acta Biochim.Biophys.Sin., 55, 2023
8IXD
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BU of 8ixd by Molmil
GMPCPP-Alpha1C/Beta2A-microtubule decorated with kinesin non-seam region
分子名称: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-1 heavy chain, ...
著者Zheng, W, Zhao, Q.Y, Diao, L, Bao, L, Cong, Y.
登録日2023-03-31
公開日2023-08-16
最終更新日2023-10-25
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Cryo-EM of alpha-tubulin isotype-containing microtubules revealed a contracted structure of alpha 4A/ beta 2A microtubules.
Acta Biochim.Biophys.Sin., 55, 2023
8IXF
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BU of 8ixf by Molmil
GMPCPP-Alpha4A/Beta2A-microtubule decorated with kinesin non-seam region
分子名称: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-1 heavy chain, ...
著者Zheng, W, Zhao, Q.Y, Diao, L, Bao, L, Cong, Y.
登録日2023-03-31
公開日2023-08-16
最終更新日2023-10-25
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Cryo-EM of alpha-tubulin isotype-containing microtubules revealed a contracted structure of alpha 4A/ beta 2A microtubules.
Acta Biochim.Biophys.Sin., 55, 2023
8TJ2
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BU of 8tj2 by Molmil
CryoEM structure of Myxococcus xanthus type IV pilus
分子名称: Type IV major pilin protein PilA
著者Zheng, W, Egelman, E.H.
登録日2023-07-20
公開日2023-08-09
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Tight-packing of large pilin subunits provides distinct structural and mechanical properties for the Myxococcus xanthus type IVa pilus.
Proc.Natl.Acad.Sci.USA, 121, 2024
8UGI
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High resolution in-situ structure of typeA supercomplex in respiratory chain (I1III2IV1,composite)
分子名称: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, ...
著者Zheng, W, Zhang, K, Zhu, J.
登録日2023-10-05
公開日2024-06-19
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (2.1 Å)
主引用文献High-resolution in situ structures of mammalian respiratory supercomplexes.
Nature, 631, 2024
8UEP
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In-situ complex I, Active-Q10 (State-alpha)
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, CARDIOLIPIN, ...
著者Zheng, W, Zhu, J, Zhang, K.
登録日2023-10-02
公開日2024-06-19
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献High-resolution in situ structures of mammalian respiratory supercomplexes.
Nature, 631, 2024
8UGK
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BU of 8ugk by Molmil
High resolution in-situ structure of complex III in respiratory supercomplex (composite)
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, CARDIOLIPIN, ...
著者Zheng, W, Zhu, J, Zhang, K.
登録日2023-10-05
公開日2024-06-19
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (2.1 Å)
主引用文献High-resolution in situ structures of mammalian respiratory supercomplexes.
Nature, 631, 2024
8UEZ
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BU of 8uez by Molmil
In-situ complex I, Active-Q10 (State-delta)
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, CARDIOLIPIN, ...
著者Zheng, W, Zhu, J, Zhang, K.
登録日2023-10-02
公開日2024-06-19
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献High-resolution in situ structures of mammalian respiratory supercomplexes.
Nature, 631, 2024
8UGD
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In-situ complex III, state I
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, CARDIOLIPIN, ...
著者Zheng, W, Zhang, K, Zhu, J.
登録日2023-10-05
公開日2024-06-19
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献High-resolution in situ structures of mammalian respiratory supercomplexes.
Nature, 631, 2024
8UET
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In-situ complex I, Deactive class02
分子名称: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, ...
著者Zheng, W, Zhu, J, Zhang, K.
登録日2023-10-02
公開日2024-06-19
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献High-resolution in situ structures of mammalian respiratory supercomplexes.
Nature, 631, 2024
8UGJ
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In-situ structure of typeB supercomplex in respiratory chain (composite)
分子名称: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, ...
著者Zheng, W, Zhang, K, Zhu, J.
登録日2023-10-05
公開日2024-06-19
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (2.3 Å)
主引用文献High-resolution in situ structures of mammalian respiratory supercomplexes.
Nature, 631, 2024
8UEW
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In-situ complex I, Deactive class05
分子名称: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, ...
著者Zheng, W, Zhu, J, Zhang, K.
登録日2023-10-02
公開日2024-06-19
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献High-resolution in situ structures of mammalian respiratory supercomplexes.
Nature, 631, 2024

 

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