1AOG
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![BU of 1aog by Molmil](/molmil-images/mine/1aog) | |
6KYF
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![BU of 6kyf by Molmil](/molmil-images/mine/6kyf) | Crystal structure of an anti-CRISPR protein | Descriptor: | AcrF11, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Niu, Y, Wang, H, Zhang, Y, Feng, Y. | Deposit date: | 2019-09-18 | Release date: | 2020-09-23 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (3.07 Å) | Cite: | A Type I-F Anti-CRISPR Protein Inhibits the CRISPR-Cas Surveillance Complex by ADP-Ribosylation. Mol.Cell, 80, 2020
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8Y1G
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![BU of 8y1g by Molmil](/molmil-images/mine/8y1g) | The 1up conformation of the HKU1-B S protein in the apo state | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | Authors: | Xia, L.Y, Zhang, Y.Y, Zhou, Q. | Deposit date: | 2024-01-24 | Release date: | 2024-05-01 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.99 Å) | Cite: | Structural basis for the recognition of HCoV-HKU1 by human TMPRSS2. Cell Res., 34, 2024
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8Y1A
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![BU of 8y1a by Molmil](/molmil-images/mine/8y1a) | 1up-1 conformation of HKU1-B S protein after incubation of the receptor | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | Authors: | Xia, L.Y, Zhang, Y.Y, Zhou, Q. | Deposit date: | 2024-01-24 | Release date: | 2024-05-01 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structural basis for the recognition of HCoV-HKU1 by human TMPRSS2. Cell Res., 34, 2024
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8Y1D
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![BU of 8y1d by Molmil](/molmil-images/mine/8y1d) | 2up-TM conformation of HKU1-B S protein after incubation of the receptor | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | Authors: | Xia, L.Y, Zhang, Y.Y, Zhou, Q. | Deposit date: | 2024-01-24 | Release date: | 2024-05-01 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Structural basis for the recognition of HCoV-HKU1 by human TMPRSS2. Cell Res., 34, 2024
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8Y1H
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![BU of 8y1h by Molmil](/molmil-images/mine/8y1h) | The 2up formation of the HKU1-B S protein in the apo state | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | Authors: | Xia, L.Y, Zhang, Y.Y, Zhou, Q. | Deposit date: | 2024-01-24 | Release date: | 2024-05-01 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.16 Å) | Cite: | Structural basis for the recognition of HCoV-HKU1 by human TMPRSS2. Cell Res., 34, 2024
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8Y1B
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![BU of 8y1b by Molmil](/molmil-images/mine/8y1b) | 1up-2 conformation of HKU1-B S protein after incubation of the receptor | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | Authors: | Xia, L.Y, Zhang, Y.Y, Zhou, Q. | Deposit date: | 2024-01-24 | Release date: | 2024-05-01 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structural basis for the recognition of HCoV-HKU1 by human TMPRSS2. Cell Res., 34, 2024
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8Y19
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![BU of 8y19 by Molmil](/molmil-images/mine/8y19) | Closed conformation of HKU1-B S protein after incubation of the receptor | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | Authors: | Xia, L.Y, Zhang, Y.Y, Zhou, Q. | Deposit date: | 2024-01-24 | Release date: | 2024-05-01 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.3 Å) | Cite: | Structural basis for the recognition of HCoV-HKU1 by human TMPRSS2. Cell Res., 34, 2024
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8Y1C
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![BU of 8y1c by Molmil](/molmil-images/mine/8y1c) | 2up-1 conformation of HKU1-B S protein after incubation of the receptor | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | Authors: | Xia, L.Y, Zhang, Y.Y, Zhou, Q. | Deposit date: | 2024-01-24 | Release date: | 2024-05-01 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structural basis for the recognition of HCoV-HKU1 by human TMPRSS2. Cell Res., 34, 2024
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8Y1F
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![BU of 8y1f by Molmil](/molmil-images/mine/8y1f) | The closed conformation of the HKU1-B S protein in the apo state | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | Authors: | Xia, L.Y, Zhang, Y.Y, Zhou, Q. | Deposit date: | 2024-01-24 | Release date: | 2024-05-01 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structural basis for the recognition of HCoV-HKU1 by human TMPRSS2. Cell Res., 34, 2024
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8Y1E
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![BU of 8y1e by Molmil](/molmil-images/mine/8y1e) | 3up-TM conformation of HKU1-B S protein after incubation of the receptor | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | Authors: | Xia, L.Y, Zhang, Y.Y, Zhou, Q. | Deposit date: | 2024-01-24 | Release date: | 2024-05-01 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Structural basis for the recognition of HCoV-HKU1 by human TMPRSS2. Cell Res., 34, 2024
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8QSO
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![BU of 8qso by Molmil](/molmil-images/mine/8qso) | Crystal structure of human Mcl-1 in complex with compound 1 | Descriptor: | (13S,16R,19S)-16-benzyl-43-ethoxy-N-methyl-7,11,14,17-tetraoxo-13-phenyl-5-oxa-2,8,12,15,18-pentaaza-1(1,4),4(1,2)-dibenzena-9(1,4)-cyclohexanacycloicosaphane-19-carboxamide, Maltose/maltodextrin-binding periplasmic protein,Induced myeloid leukemia cell differentiation protein Mcl-1, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | Authors: | Hekking, K.F.W, Gremmen, S, Maroto, S, Keefe, A.D, Zhang, Y. | Deposit date: | 2023-10-10 | Release date: | 2024-02-14 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.106 Å) | Cite: | Development of Potent Mcl-1 Inhibitors: Structural Investigations on Macrocycles Originating from a DNA-Encoded Chemical Library Screen. J.Med.Chem., 67, 2024
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4EAY
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![BU of 4eay by Molmil](/molmil-images/mine/4eay) | Crystal structures of mannonate dehydratase from Escherichia coli strain K12 complexed with D-mannonate | Descriptor: | CHLORIDE ION, D-MANNONIC ACID, MANGANESE (II) ION, ... | Authors: | Qiu, X, Zhu, Y, Yuan, Y, Zhang, Y, Liu, H, Gao, Y, Teng, M, Niu, L. | Deposit date: | 2012-03-23 | Release date: | 2013-03-27 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structural insights into decreased enzymatic activity induced by an insert sequence in mannonate dehydratase from Gram negative bacterium. J.Struct.Biol., 180, 2012
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7EO7
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![BU of 7eo7 by Molmil](/molmil-images/mine/7eo7) | Crystal structure of HCoV-NL63 3C-like protease in complex with an inhibitor Shikonin | Descriptor: | 2-[(1R)-4-methyl-1-oxidanyl-pent-3-enyl]-5,8-bis(oxidanyl)naphthalene-1,4-dione, 3C-like proteinase | Authors: | Gao, H.X, Zhang, Y.T, Zhou, X.L, Zhong, F.L, Li, J, Zhang, J. | Deposit date: | 2021-04-21 | Release date: | 2021-10-20 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.24916625 Å) | Cite: | Structure-Based Discovery and Structural Basis of a Novel Broad-Spectrum Natural Product against the Main Protease of Coronavirus. J.Virol., 96, 2022
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4EAC
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![BU of 4eac by Molmil](/molmil-images/mine/4eac) | Crystal structure of mannonate dehydratase from Escherichia coli strain K12 | Descriptor: | CHLORIDE ION, MANGANESE (II) ION, Mannonate dehydratase | Authors: | Qiu, X, Zhu, Y, Yuan, Y, Zhang, Y, Liu, H, Gao, Y, Teng, M, Niu, L. | Deposit date: | 2012-03-22 | Release date: | 2013-03-27 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural insights into decreased enzymatic activity induced by an insert sequence in mannonate dehydratase from Gram negative bacterium. J.Struct.Biol., 180, 2012
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5TT2
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![BU of 5tt2 by Molmil](/molmil-images/mine/5tt2) | |
5YST
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![BU of 5yst by Molmil](/molmil-images/mine/5yst) | RanM189D in complex with RanBP1-CRM1 | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1,Exportin-1, ... | Authors: | Sun, Q, Zhang, Y. | Deposit date: | 2017-11-15 | Release date: | 2018-11-21 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | RanM189D in complex with RanBP1-CRM1 To Be Published
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5YSU
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![BU of 5ysu by Molmil](/molmil-images/mine/5ysu) | Plumbagin in complex with CRM1-RanM189D-RanBP1 | Descriptor: | (2~{R})-2-methyl-5-oxidanyl-2,3-dihydronaphthalene-1,4-dione, CHLORIDE ION, Exportin-1,Exportin-1, ... | Authors: | Sun, Q, Zhang, Y. | Deposit date: | 2017-11-15 | Release date: | 2018-11-21 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | RanL182A in complex with RanBP1-CRM1 To Be Published
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8KC7
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![BU of 8kc7 by Molmil](/molmil-images/mine/8kc7) | Rpd3S histone deacetylase complex | Descriptor: | Chromatin modification-related protein EAF3, Histone deacetylase RPD3, Transcriptional regulatory protein RCO1, ... | Authors: | Dong, S, Li, H, Wang, M, Rasheed, N, Zou, B, Gao, X, Guan, J, Li, W, Zhang, J, Wang, C, Zhou, N, Shi, X, Li, M, Zhou, M, Huang, J, Li, H, Zhang, Y, Wong, K.H, Zhang, X, Chao, W.C.H, He, J. | Deposit date: | 2023-08-06 | Release date: | 2023-09-13 | Last modified: | 2023-10-18 | Method: | ELECTRON MICROSCOPY (3.46 Å) | Cite: | Structural basis of nucleosome deacetylation and DNA linker tightening by Rpd3S histone deacetylase complex. Cell Res., 33, 2023
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5YRO
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![BU of 5yro by Molmil](/molmil-images/mine/5yro) | RanL182A in complex with RanBP1-CRM1 | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1,Exportin-1, ... | Authors: | Sun, Q, Zhang, Y. | Deposit date: | 2017-11-09 | Release date: | 2018-11-21 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.396 Å) | Cite: | RanL182A in complex with RanBP1-CRM1 To Be Published
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5YTB
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![BU of 5ytb by Molmil](/molmil-images/mine/5ytb) | RanY197A in complex with RanBP1-CRM1 | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ... | Authors: | Sun, Q, Zhang, Y. | Deposit date: | 2017-11-17 | Release date: | 2018-11-21 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | RanY197A in complex with RanBP1-CRM1 To Be Published
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8KI5
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![BU of 8ki5 by Molmil](/molmil-images/mine/8ki5) | PhmA, a type I diterpene synthase without NST/DTE motif | Descriptor: | (2Z,6Z)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol, PhmA | Authors: | Zhang, B, Ge, H.M, Zhu, A, Zhang, Y. | Deposit date: | 2023-08-22 | Release date: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Biosynthesis of Platelet Activating Factor Antagonist Phomactins Revealing a New Class of Type I Diterpene Synthase To Be Published
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6VLS
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![BU of 6vls by Molmil](/molmil-images/mine/6vls) | Structure of C-terminal fragment of Vip3A toxin | Descriptor: | DI(HYDROXYETHYL)ETHER, Maltose/maltodextrin-binding periplasmic protein,Vip3Aa | Authors: | Jiang, K, Zhang, Y, Chen, Z, Gao, X. | Deposit date: | 2020-01-25 | Release date: | 2020-07-22 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural and Functional Insights into the C-terminal Fragment of Insecticidal Vip3A Toxin ofBacillus thuringiensis. Toxins, 12, 2020
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5WVM
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![BU of 5wvm by Molmil](/molmil-images/mine/5wvm) | Crystal structure of baeS cocrystallized with 2 mM indole | Descriptor: | Maltose-binding periplasmic protein,Two-component system sensor kinase, SULFATE ION | Authors: | Wang, W, Zhang, Y, Rang, T, Xu, D. | Deposit date: | 2016-12-26 | Release date: | 2018-01-03 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of the sensor domain of BaeS from Serratia marcescens FS14 Proteins, 85, 2017
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5WVN
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![BU of 5wvn by Molmil](/molmil-images/mine/5wvn) | Crystal structure of MBS-BaeS fusion protein | Descriptor: | Maltose-binding periplasmic protein,Two-component system sensor kinase, SULFATE ION | Authors: | Wang, W, Zhang, Y, Ran, T, Xu, D. | Deposit date: | 2016-12-26 | Release date: | 2018-01-03 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of the sensor domain of BaeS from Serratia marcescens FS14 Proteins, 85, 2017
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