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PDB: 631 results

7ZJE
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C16-2
Descriptor: Transient receptor potential cation channel subfamily V member 2,Enhanced green fluorescent protein
Authors:Zhang, L, Gourdon, P, Zygmunt, P.M.
Deposit date:2022-04-10
Release date:2023-01-18
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.12 Å)
Cite:Cannabinoid non-cannabidiol site modulation of TRPV2 structure and function.
Nat Commun, 13, 2022
7ZJG
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Probenecid
Descriptor: Transient receptor potential cation channel subfamily V member 2
Authors:Zhang, L, Gourdon, P, Zygmunt, P.M.
Deposit date:2022-04-11
Release date:2023-01-18
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.49 Å)
Cite:Cannabinoid non-cannabidiol site modulation of TRPV2 structure and function.
Nat Commun, 13, 2022
7ZJI
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Transient receptor potential cation channel subfamily V member 2,Enhanced green fluorescent protein
Descriptor: Transient receptor potential cation channel subfamily V member 2,Enhanced green fluorescent protein
Authors:Zhang, L, Gourdon, P, Zygmunt, P.M.
Deposit date:2022-04-11
Release date:2023-01-18
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cannabinoid non-cannabidiol site modulation of TRPV2 structure and function.
Nat Commun, 13, 2022
7ZJH
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TRPV2-C16+Pro-2
Descriptor: Transient receptor potential cation channel subfamily V member 2
Authors:Zhang, L, Gourdon, P, Zygmunt, P.M.
Deposit date:2022-04-11
Release date:2023-01-18
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.39 Å)
Cite:Cannabinoid non-cannabidiol site modulation of TRPV2 structure and function.
Nat Commun, 13, 2022
7ZJD
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Transient receptor potential cation channel subfamily V member 2,Enhanced green fluorescent protein
Descriptor: Transient receptor potential cation channel subfamily V member 2,Enhanced green fluorescent protein
Authors:Zhang, L, Gourdon, P, Zygmunt, P.M.
Deposit date:2022-04-10
Release date:2023-01-18
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (2.94 Å)
Cite:Cannabinoid non-cannabidiol site modulation of TRPV2 structure and function.
Nat Commun, 13, 2022
7BIP
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BU of 7bip by Molmil
Crystal structure of monooxygenase RslO1 from Streptomyces bottropensis
Descriptor: 1,2-ETHANEDIOL, 3,6,9,12,15,18,21,24,27-NONAOXANONACOSANE-1,29-DIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
Authors:Zhang, L, Zuo, C, Bechthold, A, Einsle, O.
Deposit date:2021-01-12
Release date:2021-01-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Biosynthesis of the Tricyclic Aromatic Type II Polyketide Rishirilide: New Potential Third Ring Oxygenation after Three Cyclization Steps.
Mol Biotechnol., 63, 2021
4IF2
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BU of 4if2 by Molmil
Structure of the phosphotriesterase from Mycobacterium tuberculosis
Descriptor: Phosphotriesterase homology protein, ZINC ION
Authors:Zhang, L, Li, X, Rao, Z.H.
Deposit date:2012-12-13
Release date:2013-12-18
Last modified:2022-08-24
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:The crystal structure of the phosphotriesterase from M. tuberculosis, another member of phosphotriesterase-like lactonase family.
Biochem.Biophys.Res.Commun., 510, 2019
7OQ6
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Crystal structure of cytochrome P450 Sas16 from Streptomyces asterosporus
Descriptor: Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE, THIOCYANATE ION
Authors:Zhang, L, Zhang, S, Bechthold, A, Einsle, O.
Deposit date:2021-06-02
Release date:2022-06-22
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:P450-mediated dehydrotyrosine formation during WS9326 biosynthesis proceeds via dehydrogenation of a specific acylated dipeptide substrate.
Acta Pharm Sin B, 13, 2023
5NH0
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BU of 5nh0 by Molmil
Structure of human coronavirus NL63 main protease in complex with the alpha-ketoamide tert-Butyl ((S)-4-(benzylamino)-3,4-dioxo-1-((S)-2-oxopyrrolidin-3-yl)b- utan-2-yl)carbamate (tert-butyl -GlnLactam-CO-CO-NH-benzyl)
Descriptor: 3C-like proteinase, DIMETHYL SULFOXIDE, GLYCEROL, ...
Authors:Zhang, L, Hilgenfeld, R.
Deposit date:2017-03-21
Release date:2018-05-16
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Alpha-ketoamides as broad-spectrum inhibitors of coronavirus and enterovirus replication
To Be Published
3ED0
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BU of 3ed0 by Molmil
Crystal structure of (3R)-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ) from Helicobacter pylori in complex with emodin
Descriptor: (3R)-hydroxymyristoyl-acyl carrier protein dehydratase, 3-METHYL-1,6,8-TRIHYDROXYANTHRAQUINONE, BENZAMIDINE, ...
Authors:Zhang, L, Zhang, H, Liu, W, Guo, Y, Shen, X, Jiang, H.
Deposit date:2008-09-02
Release date:2009-07-21
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Emodin targets the beta-hydroxyacyl-acyl carrier protein dehydratase from Helicobacter pylori: enzymatic inhibition assay with crystal structural and thermodynamic characterization
BMC MICROBIOL., 9, 2009
7AQA
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BU of 7aqa by Molmil
Pseudomonas stutzeri nitrous oxide reductase mutant, H382A
Descriptor: (dicuprio-$l^{3}-sulfanyl)-sulfanyl-copper, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ...
Authors:Zhang, L, Bill, E, Kroneck, P.M.H, Einsle, O.
Deposit date:2020-10-20
Release date:2021-01-27
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.497 Å)
Cite:A [3Cu:2S] cluster provides insight into the assembly and function of the Cu Z site of nitrous oxide reductase.
Chem Sci, 12, 2021
5N5O
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Structure of SARS coronavirus main protease in complex with the alpha-ketoamide (S)-N-benzyl-3-((S)-2-cinnamamido-3-cyclopropylpropanamido)-2-oxo-4-((S)-2-oxopyrrolidin-3-yl)butanamide (Cinnamoyl-cyclopropylalanine-GlnLactam-CO-CO-NH-benzyl)
Descriptor: (2~{R},3~{S})-3-[[(2~{S})-3-cyclopropyl-2-[[(~{E})-3-phenylprop-2-enoyl]amino]propanoyl]amino]-2-oxidanyl-4-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]-~{N}-(phenylmethyl)butanamide, Replicase polyprotein 1ab
Authors:Zhang, L, Hilgenfeld, R.
Deposit date:2017-02-14
Release date:2018-03-07
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Alpha-ketoamides as broad-spectrum inhibitors of coronavirus and enterovirus replication
To Be Published
3CF8
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BU of 3cf8 by Molmil
Crystal structure of (3R)-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ) from Helicobacter pylori in complex with quercetin
Descriptor: (3R)-hydroxymyristoyl-acyl carrier protein dehydratase, 3,5,7,3',4'-PENTAHYDROXYFLAVONE, BENZAMIDINE, ...
Authors:Zhang, L, Wu, D, Liu, W, Shen, X, Jiang, H.
Deposit date:2008-03-03
Release date:2008-12-09
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Three flavonoids targeting the beta-hydroxyacyl-acyl carrier protein dehydratase from Helicobacter pylori: crystal structure characterization with enzymatic inhibition assay
Protein Sci., 17, 2008
3JBL
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BU of 3jbl by Molmil
Cryo-EM Structure of the Activated NAIP2/NLRC4 Inflammasome Reveals Nucleated Polymerization
Descriptor: NLR family CARD domain-containing protein 4
Authors:Zhang, L, Chen, S, Ruan, J, Wu, J, Tong, A.B, Yin, Q, Li, Y, David, L, Lu, A, Wang, W.L, Marks, C, Ouyang, Q, Zhang, X, Mao, Y, Wu, H.
Deposit date:2015-09-05
Release date:2015-10-21
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Cryo-EM structure of the activated NAIP2-NLRC4 inflammasome reveals nucleated polymerization.
Science, 350, 2015
3D04
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BU of 3d04 by Molmil
Crystal structure of (3R)-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ) from Helicobacter pylori in complex with sakuranetin
Descriptor: (2S)-5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-2,3-dihydro-4H-chromen-4-one, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase, BENZAMIDINE, ...
Authors:Zhang, L, Kong, Y, Wu, D, Shen, X, Jiang, H.
Deposit date:2008-05-01
Release date:2008-12-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Three flavonoids targeting the beta-hydroxyacyl-acyl carrier protein dehydratase from Helicobacter pylori: crystal structure characterization with enzymatic inhibition assay
Protein Sci., 17, 2008
3CF9
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BU of 3cf9 by Molmil
Crystal structure of (3R)-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ) from Helicobacter pylori in complex with apigenin
Descriptor: (3R)-hydroxymyristoyl-acyl carrier protein dehydratase, 5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one, BENZAMIDINE, ...
Authors:Zhang, L, Wu, D, Liu, W, Shen, X, Jiang, H.
Deposit date:2008-03-03
Release date:2008-12-09
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Three flavonoids targeting the beta-hydroxyacyl-acyl carrier protein dehydratase from Helicobacter pylori: crystal structure characterization with enzymatic inhibition assay
Protein Sci., 17, 2008
6RKZ
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BU of 6rkz by Molmil
Recombinant Pseudomonas stutzeri nitrous oxide reductase, form II
Descriptor: (MU-4-SULFIDO)-TETRA-NUCLEAR COPPER ION, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ...
Authors:Zhang, L, Wuest, A, Prasser, B, Mueller, C, Einsle, O.
Deposit date:2019-04-30
Release date:2019-06-26
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.601 Å)
Cite:Functional assembly of nitrous oxide reductase provides insights into copper site maturation.
Proc.Natl.Acad.Sci.USA, 116, 2019
6RL0
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BU of 6rl0 by Molmil
Recombinant Pseudomonas stutzeri nitrous oxide reductase, form I
Descriptor: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, CHLORIDE ION, ...
Authors:Zhang, L, Wuest, A, Prasser, B, Mueller, C, Einsle, O.
Deposit date:2019-04-30
Release date:2019-06-26
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Functional assembly of nitrous oxide reductase provides insights into copper site maturation.
Proc.Natl.Acad.Sci.USA, 116, 2019
6Y7D
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BU of 6y7d by Molmil
Pseudomonas stutzeri nitrous oxide reductase mutant, H433A
Descriptor: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, CHLORIDE ION, ...
Authors:Zhang, L, Kroneck, P.M.H, Einsle, O.
Deposit date:2020-02-28
Release date:2021-01-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:A [3Cu:2S] cluster provides insight into the assembly and function of the Cu Z site of nitrous oxide reductase.
Chem Sci, 12, 2021
7AQ8
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Pseudomonas stutzeri nitrous oxide reductase mutant, H583Y/D576A
Descriptor: (MU-4-SULFIDO)-TETRA-NUCLEAR COPPER ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
Authors:Zhang, L, Bill, E, Kroneck, P.M.H, Einsle, O.
Deposit date:2020-10-20
Release date:2021-01-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.791 Å)
Cite:Histidine-Gated Proton-Coupled Electron Transfer to the Cu A Site of Nitrous Oxide Reductase.
J.Am.Chem.Soc., 143, 2021
7AQ5
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Pseudomonas stutzeri nitrous oxide reductase mutant, H583N
Descriptor: (MU-4-SULFIDO)-TETRA-NUCLEAR COPPER ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
Authors:Zhang, L, Bill, E, Kroneck, P.M.H, Einsle, O.
Deposit date:2020-10-20
Release date:2021-01-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Histidine-Gated Proton-Coupled Electron Transfer to the Cu A Site of Nitrous Oxide Reductase.
J.Am.Chem.Soc., 143, 2021
7AQ6
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BU of 7aq6 by Molmil
Pseudomonas stutzeri nitrous oxide reductase mutant, H583F
Descriptor: (MU-4-SULFIDO)-TETRA-NUCLEAR COPPER ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
Authors:Zhang, L, Bill, E, Kroneck, P.M.H, Einsle, O.
Deposit date:2020-10-20
Release date:2021-01-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.514 Å)
Cite:Histidine-Gated Proton-Coupled Electron Transfer to the Cu A Site of Nitrous Oxide Reductase.
J.Am.Chem.Soc., 143, 2021
7AQ7
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BU of 7aq7 by Molmil
Pseudomonas stutzeri nitrous oxide reductase mutant, H583Y
Descriptor: (MU-4-SULFIDO)-TETRA-NUCLEAR COPPER ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
Authors:Zhang, L, Bill, E, Kroneck, P.M.H, Einsle, O.
Deposit date:2020-10-20
Release date:2021-01-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.608 Å)
Cite:Histidine-Gated Proton-Coupled Electron Transfer to the Cu A Site of Nitrous Oxide Reductase.
J.Am.Chem.Soc., 143, 2021
7AQ4
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Pseudomonas stutzeri nitrous oxide reductase mutant, H583E
Descriptor: (MU-4-SULFIDO)-TETRA-NUCLEAR COPPER ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
Authors:Zhang, L, Bill, E, Kroneck, P.M.H, Einsle, O.
Deposit date:2020-10-20
Release date:2021-01-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.708 Å)
Cite:Histidine-Gated Proton-Coupled Electron Transfer to the Cu A Site of Nitrous Oxide Reductase.
J.Am.Chem.Soc., 143, 2021
7AQ3
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Pseudomonas stutzeri nitrous oxide reductase mutant, H583D
Descriptor: (MU-4-SULFIDO)-TETRA-NUCLEAR COPPER ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
Authors:Zhang, L, Bill, E, Kroneck, P.M.H, Einsle, O.
Deposit date:2020-10-20
Release date:2021-01-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.639 Å)
Cite:Histidine-Gated Proton-Coupled Electron Transfer to the Cu A Site of Nitrous Oxide Reductase.
J.Am.Chem.Soc., 143, 2021

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