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PDB: 50 件
1X24
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BU of 1x24 by Molmil
Prl-1 (ptp4a)
分子名称: protein tyrosine phosphatase 4a1
著者Zhang, Z.Y, Sun, J.P, Liu, S, Wang, W.Q, Yang, H.
登録日2005-04-20
公開日2005-10-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure and Biochemical Properties of PRL-1, a Phosphatase Implicated in Cell Growth, Differentiation, and Tumor Invasion(,)
Biochemistry, 44, 2005
4RDD
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BU of 4rdd by Molmil
Co-crystal structure of SHP2 in complex with a Cefsulodin derivative
分子名称: 1-({(2R)-4-carboxy-2-[(R)-carboxy{[(2R)-2-phenyl-2-sulfoacetyl]amino}methyl]-3,6-dihydro-2H-1,3-thiazin-5-yl}methyl)pyridinium, Tyrosine-protein phosphatase non-receptor type 11
著者Zhang, Z.Y, Yu, Z.H, He, R, Zhang, R.Y.
登録日2014-09-18
公開日2015-07-01
最終更新日2015-12-16
実験手法X-RAY DIFFRACTION (1.601 Å)
主引用文献Exploring the Existing Drug Space for Novel pTyr Mimetic and SHP2 Inhibitors.
ACS Med Chem Lett, 6, 2015
8X61
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Cryo-EM structure of ATP-bound FtsE(E163Q)X
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cell division ATP-binding protein FtsE, Cell division protein FtsX
著者Zhang, Z.Y, Chen, Y.T.
登録日2023-11-20
公開日2024-05-08
実験手法ELECTRON MICROSCOPY (3.05 Å)
主引用文献Cryo-EM structure of ATP-bound FtsE(E163Q)X
To Be Published
3BM8
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crystal structure of YopH mutant D356A complexed with irreversible inhibitor PVSN
分子名称: Tyrosine-protein phosphatase yopH, phenyl ethenesulfonate
著者Zhang, Z.Y, Liu, S.J.
登録日2007-12-12
公開日2008-06-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Aryl vinyl sulfonates and sulfones as active site-directed and mechanism-based probes for protein tyrosine phosphatases.
J.Am.Chem.Soc., 130, 2008
6Y6I
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BU of 6y6i by Molmil
lipopolysaccharide outer core galactosyltransferase WaaB and UDP complex
分子名称: Lipopolysaccharide 1,6-galactosyltransferase, URIDINE-5'-DIPHOSPHATE
著者Zhang, Z.Y, Ashworth, G, Wang, Z.S, Zhu, X.F, Dong, C.J.
登録日2020-02-26
公開日2021-03-31
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Structural insights into the lipopolysaccharide outer core galactosyltransferase WaaB
To Be Published
6Y6G
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lipopolysaccharide outer core galactosyltransferase WaaB apo form
分子名称: Lipopolysaccharide 1,6-galactosyltransferase
著者Zhang, Z.Y, Ashworth, G, Wang, Z.S, Zhu, X.F, Dong, C.J.
登録日2020-02-26
公開日2021-03-31
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Structural insights into the lipopolysaccharide outer core galactosyltransferase WaaB
To Be Published
3D8X
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BU of 3d8x by Molmil
Crystal Structure of Saccharomyces cerevisiae NDPPH Dependent Thioredoxin Reductase 1
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Thioredoxin reductase 1
著者Zhang, Z.Y, Bao, R, Yu, J, Chen, Y.X, Zhou, C.-Z.
登録日2008-05-26
公開日2008-12-09
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of Saccharomyces cerevisiae cytoplasmic thioredoxin reductase Trr1 reveals the structural basis for species-specific recognition of thioredoxin
Biochim.Biophys.Acta, 1794, 2009
6LR7
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BU of 6lr7 by Molmil
Crystal structure of GFPuv complexed with the nanobody LaG16 at 1.67 Angstron resolution
分子名称: Green fluorescent protein, Nanobody LaG16
著者Zhang, Z.Y, Ding, Y, Hattori, M.
登録日2020-01-15
公開日2020-04-29
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Structure-based engineering of anti-GFP nanobody tandems as ultra-high-affinity reagents for purification.
Sci Rep, 10, 2020
7V52
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Structure of AdaV
分子名称: AdaV, FE (III) ION
著者Zhang, Z.Y, Chen, W.Q, Zhai, G.Q, Zhang, M.
登録日2021-08-16
公開日2022-08-24
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Structural Insight into the Catalytic Mechanism of Non-Heme Iron Halogenase AdaV in 2'-Chloropentostatin Biosynthesis
Acs Catalysis, 12, 2022
7V57
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Structure of AdaV
分子名称: 2-OXOGLUTARIC ACID, AdaV, CHLORIDE ION, ...
著者Zhang, Z.Y, Chen, W.Q, Zhai, G.Q, Zhang, M.
登録日2021-08-16
公開日2022-08-24
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural Insight into the Catalytic Mechanism of Non-Heme Iron Halogenase AdaV in 2'-Chloropentostatin Biosynthesis
Acs Catalysis, 12, 2022
7V54
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Structure of AdaV
分子名称: AdaV, FE (III) ION
著者Zhang, Z.Y, Chen, W.Q, Zhai, G.Q, Zhang, M.
登録日2021-08-16
公開日2022-08-24
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Structural Insight into the Catalytic Mechanism of Non-Heme Iron Halogenase AdaV in 2'-Chloropentostatin Biosynthesis
Acs Catalysis, 12, 2022
7V56
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Structure of AdaV
分子名称: AdaV, FE (III) ION
著者Zhang, Z.Y, Chen, W.Q, Zhai, G.Q, Zhang, M.
登録日2021-08-16
公開日2022-08-24
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Structural Insight into the Catalytic Mechanism of Non-Heme Iron Halogenase AdaV in 2'-Chloropentostatin Biosynthesis
Acs Catalysis, 12, 2022
7V7X
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Structure of H194A AdaV
分子名称: 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, AdaV
著者Zhang, Z.Y, Chen, W.Q, Zhai, G.Q, Zhang, M.
登録日2021-08-22
公開日2022-08-31
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural Insight into the Catalytic Mechanism of Non-Heme Iron Halogenase AdaV in 2'-Chloropentostatin Biosynthesis
Acs Catalysis, 12, 2022
8INP
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A reversible glycosyltransferase of tectorigenin - Bc7OUGT
分子名称: Bc7OUGT, URIDINE-5'-DIPHOSPHATE, beta-D-glucopyranose
著者Zhang, Z.Y, Lu, L, Guan, Z.F, Cheng, W.J.
登録日2023-03-10
公開日2023-08-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Functional characterization and structural basis of a reversible glycosyltransferase involves in plant chemical defence.
Plant Biotechnol J, 21, 2023
8ITA
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BU of 8ita by Molmil
A reversible glycosyltransferase of tectorigenin - Bc7OUGT complexed with UDP and tectorigenin
分子名称: 3-(4-hydroxyphenyl)-6-methoxy-5,7-bis(oxidanyl)chromen-4-one, Bc7OUGT, URIDINE-5'-DIPHOSPHATE
著者Zhang, Z.Y, Lu, L, Guan, Z.F, Cheng, W.J.
登録日2023-03-22
公開日2023-08-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Functional characterization and structural basis of a reversible glycosyltransferase involves in plant chemical defence.
Plant Biotechnol J, 21, 2023
7FH5
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Structure of AdaV
分子名称: AdaV, CHLORIDE ION, FE (III) ION
著者Zhang, Z.Y, Chen, W.Q, Zhai, G.Q, Zhang, M.
登録日2021-07-29
公開日2022-08-03
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Insight into the Catalytic Mechanism of Non-Heme Iron Halogenase AdaV in 2'-Chloropentostatin Biosynthesis
Acs Catalysis, 12, 2022
7EY5
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BU of 7ey5 by Molmil
Local CryoEM structure of the SARS-CoV-2 S6PV2 in complex with BD-771 Fab and BD-821 Fab
分子名称: BD-771H, BD-771L, BD-821H, ...
著者Zhang, Z.Y.
登録日2021-05-29
公開日2021-09-08
最終更新日2022-02-16
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structures of SARS-CoV-2 B.1.351 neutralizing antibodies provide insights into cocktail design against concerning variants.
Cell Res., 31, 2021
1EEO
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BU of 1eeo by Molmil
CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH ACETYL-E-L-E-F-PTYR-M-D-Y-E-NH2
分子名称: ACETYL-E-L-E-F-PTYR-M-D-Y-E-NH2 PEPTIDE, MAGNESIUM ION, PROTEIN TYROSINE PHOSPHATASE 1B
著者Sarmiento, M, Puius, Y.A, Vetter, S.W, Lawrence, D.S, Almo, S.C, Zhang, Z.Y.
登録日2000-02-01
公開日2001-02-01
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis of plasticity in protein tyrosine phosphatase 1B substrate recognition.
Biochemistry, 39, 2000
1EEN
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BU of 1een by Molmil
CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH ACETYL-D-A-D-BPA-PTYR-L-I-P-Q-Q-G
分子名称: ACETIC ACID, ALA-ASP-PBF-PTR-LEU-ILE-PRO, MAGNESIUM ION, ...
著者Puius, Y.A, Zhao, Y, Almo, S.C, Zhang, Z.Y.
登録日2000-02-01
公開日2001-02-01
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis of plasticity in protein tyrosine phosphatase 1B substrate recognition.
Biochemistry, 39, 2000
1RXD
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BU of 1rxd by Molmil
Crystal structure of human protein tyrosine phosphatase 4A1
分子名称: protein tyrosine phosphatase type IVA, member 1; Protein tyrosine phosphatase IVA1
著者Sun, J.P, Fedorov, A.A, Almo, S.C, Zhang, Z.Y, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2003-12-18
公開日2004-12-28
最終更新日2021-02-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural genomics of protein phosphatases.
J.STRUCT.FUNCT.GENOM., 8, 2007
2FYS
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BU of 2fys by Molmil
Crystal structure of Erk2 complex with KIM peptide derived from MKP3
分子名称: Dual specificity protein phosphatase 6, Mitogen-activated protein kinase 1
著者Liu, S, Sun, J.P, Zhou, B, Zhang, Z.Y.
登録日2006-02-08
公開日2006-04-11
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis of docking interactions between ERK2 and MAP kinase phosphatase 3
Proc.Natl.Acad.Sci.Usa, 103, 2006
5BK8
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Cancer-associated SHP2/T507K mutant
分子名称: Tyrosine-protein phosphatase non-receptor type 11
著者Yu, Z.H, Zhang, R.Y, Zhang, Z.Y.
登録日2019-06-01
公開日2020-04-08
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Mechanistic insights explain the transforming potential of the T507K substitution in the protein-tyrosine phosphatase SHP2.
J.Biol.Chem., 295, 2020
4DGX
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LEOPARD Syndrome-Associated SHP2/Y279C mutant
分子名称: Tyrosine-protein phosphatase non-receptor type 11
著者Yu, Z.H, Xu, J, Walls, C.D, Chen, L, Zhang, S, Wu, L, Wang, L.N, Liu, S.J, Zhang, Z.Y.
登録日2012-01-27
公開日2013-03-06
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and Mechanistic Insights into LEOPARD Syndrome-Associated SHP2 Mutations.
J.Biol.Chem., 288, 2013
4DGP
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The wild-type Src homology 2 (SH2)-domain containing protein tyrosine phosphatase-2 (SHP2)
分子名称: Tyrosine-protein phosphatase non-receptor type 11
著者Yu, Z.H, Xu, J, Walls, C.D, Chen, L, Zhang, S, Wu, L, Wang, L.N, Liu, S.J, Zhang, Z.Y.
登録日2012-01-26
公開日2013-03-06
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and Mechanistic Insights into LEOPARD Syndrome-Associated SHP2 Mutations.
J.Biol.Chem., 288, 2013
4OHE
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LEOPARD Syndrome-Associated SHP2/G464A mutant
分子名称: Tyrosine-protein phosphatase non-receptor type 11
著者Yu, Z.H, Zhang, R.Y, Walls, C.D, Chen, L, Zhang, S, Wu, L, Wang, L, Liu, S, Zhang, Z.Y.
登録日2014-01-17
公開日2014-09-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.506 Å)
主引用文献Molecular basis of gain-of-function LEOPARD syndrome-associated SHP2 mutations.
Biochemistry, 53, 2014

 

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