6LJW
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![BU of 6ljw by Molmil](/molmil-images/mine/6ljw) | Crystal structure of human FABP4 in complex with a novel inhibitor | 分子名称: | 1,2-ETHANEDIOL, 2-phenylazanylbenzoic acid, Fatty acid-binding protein, ... | 著者 | Su, H.X, Zhang, X.L, Li, M.J, Xu, Y.C. | 登録日 | 2019-12-17 | 公開日 | 2020-04-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Exploration of Fragment Binding Poses Leading to Efficient Discovery of Highly Potent and Orally Effective Inhibitors of FABP4 for Anti-inflammation. J.Med.Chem., 63, 2020
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8W8K
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![BU of 8w8k by Molmil](/molmil-images/mine/8w8k) | Crystal structures of HSP90 and the compound Ganetespid in the "closed" conformation | 分子名称: | 5-[2,4-dihydroxy-5-(propan-2-yl)phenyl]-4-(1-methyl-1H-indol-5-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one, Heat shock protein HSP 90-alpha, MAGNESIUM ION | 著者 | Xu, C, Zhang, X.L, Bai, F. | 登録日 | 2023-09-03 | 公開日 | 2024-04-17 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Accurate Characterization of Binding Kinetics and Allosteric Mechanisms for the HSP90 Chaperone Inhibitors Using AI-Augmented Integrative Biophysical Studies. Jacs Au, 4, 2024
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8KI4
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![BU of 8ki4 by Molmil](/molmil-images/mine/8ki4) | Crystal structure of human HSP90 in intermediate state | 分子名称: | 1,2-ETHANEDIOL, Heat shock protein HSP 90-alpha | 著者 | Xu, C, Zhang, X.L, Bai, F. | 登録日 | 2023-08-22 | 公開日 | 2024-04-17 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Accurate Characterization of Binding Kinetics and Allosteric Mechanisms for the HSP90 Chaperone Inhibitors Using AI-Augmented Integrative Biophysical Studies. Jacs Au, 4, 2024
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3S8M
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![BU of 3s8m by Molmil](/molmil-images/mine/3s8m) | The Crystal Structure of FabV | 分子名称: | Enoyl-ACP Reductase | 著者 | Li, H, Zhang, X.L, Bi, L.J, He, J, Jiang, T. | 登録日 | 2011-05-29 | 公開日 | 2011-11-16 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Determination of the Crystal Structure and Active Residues of FabV, the Enoyl-ACP Reductase from Xanthomonas oryzae. Plos One, 6, 2011
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7WVK
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![BU of 7wvk by Molmil](/molmil-images/mine/7wvk) | Crystal structure of human WDR5 in complex with compound 19 | 分子名称: | 1,2-ETHANEDIOL, 1-[2,5-bis(chloranyl)phenyl]sulfonylbenzimidazole, GLYCEROL, ... | 著者 | Han, Q.L, Zhang, X.L, Wang, L, Ren, P.X, Cao, Y, Li, K, Bai, F. | 登録日 | 2022-02-10 | 公開日 | 2022-10-19 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | 主引用文献 | Discovery, evaluation and mechanism study of WDR5-targeted small molecular inhibitors for neuroblastoma. Acta Pharmacol.Sin., 44, 2023
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7XC8
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![BU of 7xc8 by Molmil](/molmil-images/mine/7xc8) | Crystal structure of cotton alpha-like expansin GhEXLA1 | 分子名称: | Beta-expansin, DI(HYDROXYETHYL)ETHER, GLYCEROL | 著者 | Zhao, F, Men, S, Xue, Y, Tu, L.L, Yin, P, Zhang, X.L. | 登録日 | 2022-03-23 | 公開日 | 2023-05-17 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Crystal structure of cotton alpha-like expansin GhEXLA1 To Be Published
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7YF0
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![BU of 7yf0 by Molmil](/molmil-images/mine/7yf0) | In situ structure of polymerase complex of mammalian reovirus in the core | 分子名称: | Lambda-2 protein, Mu-2 protein, RNA helicase, ... | 著者 | Bao, K.Y, Zhang, X.L, Li, D.Y, Zhu, P. | 登録日 | 2022-07-07 | 公開日 | 2023-03-29 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | In situ structures of polymerase complex of mammalian reovirus illuminate RdRp activation and transcription regulation. Proc.Natl.Acad.Sci.USA, 119, 2022
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7YED
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![BU of 7yed by Molmil](/molmil-images/mine/7yed) | In situ structure of polymerase complex of mammalian reovirus in the elongation state | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, Lambda-2 protein, MAGNESIUM ION, ... | 著者 | Bao, K.Y, Zhang, X.L, Li, D.Y, Zhu, P. | 登録日 | 2022-07-05 | 公開日 | 2023-04-05 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | In situ structures of polymerase complex of mammalian reovirus illuminate RdRp activation and transcription regulation. Proc.Natl.Acad.Sci.USA, 119, 2022
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7YEV
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![BU of 7yev by Molmil](/molmil-images/mine/7yev) | In situ structure of polymerase complex of mammalian reovirus in the pre-elongation state | 分子名称: | Lambda-2 protein, Mu-2 protein, RNA helicase, ... | 著者 | Bao, K.Y, Zhang, X.L, Li, D.Y, Zhu, P. | 登録日 | 2022-07-06 | 公開日 | 2023-03-29 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | In situ structures of polymerase complex of mammalian reovirus illuminate RdRp activation and transcription regulation. Proc.Natl.Acad.Sci.USA, 119, 2022
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7YEZ
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![BU of 7yez by Molmil](/molmil-images/mine/7yez) | In situ structure of polymerase complex of mammalian reovirus in the reloaded state | 分子名称: | Lambda-2 protein, Mu-2 protein, RNA helicase, ... | 著者 | Bao, K.Y, Zhang, X.L, Li, D.Y, Zhu, P. | 登録日 | 2022-07-06 | 公開日 | 2023-03-29 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | In situ structures of polymerase complex of mammalian reovirus illuminate RdRp activation and transcription regulation. Proc.Natl.Acad.Sci.USA, 119, 2022
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7YFE
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![BU of 7yfe by Molmil](/molmil-images/mine/7yfe) | In situ structure of polymerase complex of mammalian reovirus in virion | 分子名称: | Lambda-2 protein, Mu-2 protein, RNA (5'-R(P*AP*CP*GP*AP*UP*UP*AP*GP*C)-3'), ... | 著者 | Bao, K.Y, Zhang, X.L, Li, D.Y, Zhu, P. | 登録日 | 2022-07-08 | 公開日 | 2023-03-29 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | In situ structures of polymerase complex of mammalian reovirus illuminate RdRp activation and transcription regulation. Proc.Natl.Acad.Sci.USA, 119, 2022
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7D5K
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![BU of 7d5k by Molmil](/molmil-images/mine/7d5k) | CryoEM structure of cotton cellulose synthase isoform 7 | 分子名称: | Cellulose synthase, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose | 著者 | Guan, Z.Y, Xue, Y, Yin, P, Zhang, X.L. | 登録日 | 2020-09-26 | 公開日 | 2021-07-28 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structural insights into homotrimeric assembly of cellulose synthase CesA7 from Gossypium hirsutum. Plant Biotechnol J, 19, 2021
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