1I85
| CRYSTAL STRUCTURE OF THE CTLA-4/B7-2 COMPLEX | 分子名称: | CYTOTOXIC T-LYMPHOCYTE-ASSOCIATED PROTEIN 4, T LYMPHOCYTE ACTIVATION ANTIGEN CD86 | 著者 | Schwartz, J.-C.D, Zhang, X, Fedorov, A.A, Nathenson, S.G, Almo, S.C. | 登録日 | 2001-03-12 | 公開日 | 2001-04-04 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural basis for co-stimulation by the human CTLA-4/B7-2 complex. Nature, 410, 2001
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1ICC
| RAT OUTER MITOCHONDRIAL MEMBRANE CYTOCHROME B5 | 分子名称: | CYTOCHROME B5 OUTER MITOCHONDRIAL MEMBRANE ISOFORM, MAGNESIUM ION, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Terzyan, S, Zhang, X. | 登録日 | 2001-03-30 | 公開日 | 2001-09-19 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Probing the differences between rat liver outer mitochondrial membrane cytochrome b5 and microsomal cytochromes b5. Biochemistry, 40, 2001
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6Z3A
| Mec1-Ddc2 (wild-type) in complex with AMP-PNP | 分子名称: | DNA damage checkpoint protein LCD1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase MEC1, ... | 著者 | Yates, L.A, Zhang, X. | 登録日 | 2020-05-19 | 公開日 | 2020-11-11 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Mechanism of auto-inhibition and activation of Mec1 ATR checkpoint kinase. Nat.Struct.Mol.Biol., 28, 2021
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6Z2X
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6Z2W
| Mec1-Ddc2 (F2244L mutant) in complex with Mg AMP-PNP | 分子名称: | DNA damage checkpoint protein LCD1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | Yates, L.A, Zhang, X. | 登録日 | 2020-05-18 | 公開日 | 2020-11-11 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (2.82 Å) | 主引用文献 | Mechanism of auto-inhibition and activation of Mec1 ATR checkpoint kinase. Nat.Struct.Mol.Biol., 28, 2021
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3UT7
| Structural view of a non Pfam singleton and crystal packing analysis | 分子名称: | Putative uncharacterized protein, SULFATE ION | 著者 | Cheng, C, Shaw, N, Zhang, X, Zhang, M, Ding, W, Wang, B.C, Liu, Z.J. | 登録日 | 2011-11-25 | 公開日 | 2012-03-28 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (3.01 Å) | 主引用文献 | Structural view of a non pfam singleton and crystal packing analysis. Plos One, 7, 2012
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3UT8
| Structural view of a non Pfam singleton and crystal packing analysis | 分子名称: | IODIDE ION, Putative uncharacterized protein | 著者 | Cheng, C, Shaw, N, Zhang, X, Zhang, M, Ding, W, Wang, B.C, Liu, Z.J. | 登録日 | 2011-11-25 | 公開日 | 2012-03-28 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.168 Å) | 主引用文献 | Structural view of a non pfam singleton and crystal packing analysis. Plos One, 7, 2012
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3UT4
| Structural view of a non Pfam singleton and crystal packing analysis | 分子名称: | Putative uncharacterized protein | 著者 | Cheng, C, Shaw, N, Zhang, X, Zhang, M, Ding, W, Wang, B.C, Liu, Z.J. | 登録日 | 2011-11-25 | 公開日 | 2012-03-28 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Structural view of a non pfam singleton and crystal packing analysis. Plos One, 7, 2012
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7SII
| Human STING bound to both cGAMP and 1-[(2-chloro-6-fluorophenyl)methyl]-3,3-dimethyl-2-oxo-N-[(2,4,6-trifluorophenyl)methyl]-2,3-dihydro-1H-indole-6-carboxamide (Compound 53) | 分子名称: | 1-[(2-chloro-6-fluorophenyl)methyl]-3,3-dimethyl-2-oxo-N-[(2,4,6-trifluorophenyl)methyl]-2,3-dihydro-1H-indole-6-carboxamide, Stimulator of interferon genes protein, cGAMP | 著者 | Lu, D, Shang, G, Jie, L, Lu, Y, Bai, X.C, Zhang, X. | 登録日 | 2021-10-14 | 公開日 | 2022-02-02 | 最終更新日 | 2022-05-04 | 実験手法 | ELECTRON MICROSCOPY (3.45 Å) | 主引用文献 | Activation of STING by targeting a pocket in the transmembrane domain. Nature, 604, 2022
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8EXF
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8EXE
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5CP7
| Crystal Structure of an Antigen-Binding Fragment of Monoclonal Antibody against Sulfonamides | 分子名称: | Heavy Chain of Antigen-Binding Fragment of Monoclonal Antibody of 4C7, Light Chain of Antigen-Binding Fragment of Monoclonal Antibody of 4C7 | 著者 | Wang, Z, Shen, J, Li, C, Li, Y, Wen, K, Yu, X, Zhang, X. | 登録日 | 2015-07-21 | 公開日 | 2015-08-05 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.01 Å) | 主引用文献 | Class-specific Monoclonal Antibodies and Dihydropteroate Synthase in Bioassays used for the Detection of Sulfonamides: Structural Insights into Recognition Diversity. Anal. Chem., 91, 2019
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5CP3
| Crystal Structure of an Antigen-Binding Fragment of Monoclonal Antibody against Sulfonamides in Complex with Sulfathiazole | 分子名称: | 4-amino-N-(1,3-thiazol-2-yl)benzenesulfonamide, CALCIUM ION, GLYCEROL, ... | 著者 | Wang, Z, Shen, J, Li, C, Li, Y, Wen, K, Yu, X, Zhang, X. | 登録日 | 2015-07-21 | 公開日 | 2015-08-05 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Class-specific Monoclonal Antibodies and Dihydropteroate Synthase in Bioassays used for the Detection of Sulfonamides: Structural Insights into Recognition Diversity. Anal. Chem., 91, 2019
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1P9E
| Crystal Structure Analysis of Methyl Parathion Hydrolase from Pseudomonas sp WBC-3 | 分子名称: | CADMIUM ION, Methyl Parathion Hydrolase, POTASSIUM ION, ... | 著者 | Dong, Y, Sun, L, Bartlam, M, Rao, Z, Zhang, X. | 登録日 | 2003-05-11 | 公開日 | 2004-05-25 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal Structure Analysis of Methyl Parathion Hydrolase from Pseudomonas sp WBC-3 To be Published
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2B36
| Crystal structure of Mycobacterium tuberculosis enoyl reductase (InhA) inhibited by 5-pentyl-2-phenoxyphenol | 分子名称: | 5-PENTYL-2-PHENOXYPHENOL, Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Sullivan, T.J, Truglio, J.J, Novichenok, P, Stratton, C, Zhang, X, Kaur, T, Johnson, F, Boyne, M.S, Amin, A. | 登録日 | 2005-09-19 | 公開日 | 2006-03-07 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | High Affinity InhA Inhibitors with Activity against Drug-Resistant Strains
of Mycobacterium tuberculosis ACS Chem.Biol., 1, 2006
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2B35
| Crystal structure of Mycobacterium tuberculosis enoyl reductase (InhA) inhibited by triclosan | 分子名称: | Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE, TRICLOSAN | 著者 | Sullivan, T.J, Truglio, J.J, Novichenok, P, Stratton, C, Zhang, X, Kaur, T, Johnson, F, Boyne, M.S, Amin, A. | 登録日 | 2005-09-19 | 公開日 | 2006-03-07 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | High Affinity InhA Inhibitors with Activity against Drug-Resistant Strains
of Mycobacterium tuberculosis ACS Chem.Biol., 1, 2006
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6S8F
| Structure of nucleotide-bound Tel1/ATM | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase TEL1,Serine/threonine-protein kinase TEL1,Serine/threonine-protein kinase TEL1,Serine/threonine-protein kinase TEL1,Serine/threonine-protein kinase TEL1 | 著者 | Yates, L.A, Williams, R.M, Ayala, R, Zhang, X. | 登録日 | 2019-07-09 | 公開日 | 2019-10-30 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Cryo-EM Structure of Nucleotide-Bound Tel1ATMUnravels the Molecular Basis of Inhibition and Structural Rationale for Disease-Associated Mutations. Structure, 28, 2020
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2B37
| Crystal structure of Mycobacterium tuberculosis enoyl reductase (InhA) inhibited by 5-octyl-2-phenoxyphenol | 分子名称: | 5-OCTYL-2-PHENOXYPHENOL, Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Sullivan, T.J, Truglio, J.J, Novichenok, P, Stratton, C, Zhang, X, Kaur, T, Johnson, F, Boyne, M.S, Amin, A. | 登録日 | 2005-09-19 | 公開日 | 2006-03-07 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | High Affinity InhA Inhibitors with Activity against Drug-Resistant Strains
of Mycobacterium tuberculosis ACS Chem.Biol., 1, 2006
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2BJW
| PspF AAA domain | 分子名称: | PSP OPERON TRANSCRIPTIONAL ACTIVATOR | 著者 | Rappas, M, Schumacher, J, Beuron, F, Niwa, H, Bordes, P, Wigneshweraraj, S, Keetch, C.A, Robinson, C.V, Buck, M, Zhang, X. | 登録日 | 2005-02-08 | 公開日 | 2005-03-31 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structural Insights Into the Activity of Enhancer-Binding Proteins Science, 307, 2005
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2BJV
| Crystal Structure of PspF(1-275) R168A mutant | 分子名称: | PSP OPERON TRANSCRIPTIONAL ACTIVATOR | 著者 | Rappas, M, Schumacher, J, Beuron, F, Niwa, H, Bordes, P, Wigneshweraraj, S, Keetch, C.A, Robinson, C.V, Buck, M, Zhang, X. | 登録日 | 2005-02-08 | 公開日 | 2005-03-31 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural Insights Into the Activity of Enhancer-Binding Proteins Science, 307, 2005
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2C96
| Structural basis of the nucleotide driven conformational changes in the AAA domain of transcription activator PspF | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, PSP OPERON TRANSCRIPTIONAL ACTIVATOR | 著者 | Rappas, M, Schumacher, J, Niwa, H, Buck, M, Zhang, X. | 登録日 | 2005-12-09 | 公開日 | 2006-02-01 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural Basis of the Nucleotide Driven Conformational Changes in the Aaa(+) Domain of Transcription Activator Pspf. J.Mol.Biol., 357, 2006
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6HTS
| Cryo-EM structure of the human INO80 complex bound to nucleosome | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin-related protein 5, Chromatin-remodeling ATPase INO80, ... | 著者 | Ayala, R, Willhoft, O, Aramayo, R.J, Wilkinson, M, McCormack, E.A, Ocloo, L, Wigley, D.B, Zhang, X. | 登録日 | 2018-10-04 | 公開日 | 2018-11-07 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | 主引用文献 | Structure and regulation of the human INO80-nucleosome complex. Nature, 556, 2018
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6I52
| Yeast RPA bound to ssDNA | 分子名称: | DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), Replication factor A protein 1, Replication factor A protein 2, ... | 著者 | Yates, L.A, Aramayo, R.J, Zhang, X. | 登録日 | 2018-11-12 | 公開日 | 2018-12-19 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | 主引用文献 | A structural and dynamic model for the assembly of Replication Protein A on single-stranded DNA. Nat Commun, 9, 2018
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2C98
| Structural basis of the nucleotide driven conformational changes in the AAA domain of transcription activator PspF | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, PSP OPERON TRANSCRIPTIONAL ACTIVATOR | 著者 | Rappas, M, Schumacher, J, Niwa, H, Buck, M, Zhang, X. | 登録日 | 2005-12-09 | 公開日 | 2006-02-01 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural Basis of the Nucleotide Driven Conformational Changes in the Aaa(+) Domain of Transcription Activator Pspf. J.Mol.Biol., 357, 2006
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2C99
| Structural basis of the nucleotide driven conformational changes in the AAA domain of transcription activator PspF | 分子名称: | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, PSP OPERON TRANSCRIPTIONAL ACTIVATOR | 著者 | Rappas, M, Schumacher, J, Niwa, H, Buck, M, Zhang, X. | 登録日 | 2005-12-09 | 公開日 | 2006-02-01 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural Basis of the Nucleotide Driven Conformational Changes in the Aaa(+) Domain of Transcription Activator Pspf. J.Mol.Biol., 357, 2006
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