8JPR
 
 | | Cryo-EM structure of Y553C human ClC-6 | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, H(+)/Cl(-) exchange transporter 6, ... | | 著者 | Zhang, S.S. | | 登録日 | 2023-06-12 | | 公開日 | 2023-09-20 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Molecular basis of ClC-6 function and its impairment in human disease
Sci Adv, 2023
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8JPO
 | | Cryo-EM structure of ATP bound human ClC-6 | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, H(+)/Cl(-) exchange transporter 6, ... | | 著者 | Zhang, S.S. | | 登録日 | 2023-06-12 | | 公開日 | 2023-09-20 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Molecular basis of ClC-6 function and its impairment in human disease
Sci Adv, 2023
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8JPJ
 | | Cryo-EM structure of ClC-6 apo state | | 分子名称: | CHLORIDE ION, H(+)/Cl(-) exchange transporter 6 | | 著者 | Zhang, S.S. | | 登録日 | 2023-06-12 | | 公開日 | 2023-09-20 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Molecular basis of ClC-6 function and its impairment in human disease
Sci Adv, 2023
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8JZX
 | | SLC15A4 inhibitor complex | | 分子名称: | 2-(4-ethoxyphenyl)-N-[3-[(2R)-2-methylpiperidin-1-yl]propyl]quinoline-4-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | | 著者 | Zhang, S.S, Chen, X.D, Xie, M. | | 登録日 | 2023-07-06 | | 公開日 | 2023-09-27 | | 最終更新日 | 2023-12-13 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | A conformation-locking inhibitor of SLC15A4 with TASL proteostatic anti-inflammatory activity.
Nat Commun, 14, 2023
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8JZS
 | | Outward-facing SLC15A4 dimer | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, lysosomal transporter | | 著者 | Zhang, S.S, Chen, X.D, Xie, M. | | 登録日 | 2023-07-06 | | 公開日 | 2023-09-27 | | 最終更新日 | 2023-12-13 | | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | | 主引用文献 | Structural basis for recruitment of TASL by SLC15A4 in human endolysosomal TLR signaling.
Nat Commun, 14, 2023
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8JZU
 | | SLC15A4_TASL complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, TLR adapter,Green fluorescent protein, TSLAA-EGPF tag fusion protein | | 著者 | Zhang, S.S, Chen, X.D, Xie, M. | | 登録日 | 2023-07-06 | | 公開日 | 2023-09-27 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | | 主引用文献 | Structural basis for recruitment of TASL by SLC15A4 in human endolysosomal TLR signaling.
Nat Commun, 14, 2023
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8JZR
 | | Outward_facing SLC15A4 monomer | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, lysosomal transporter,ALFA tag | | 著者 | Zhang, S.S, Chen, X.D, Xie, M. | | 登録日 | 2023-07-06 | | 公開日 | 2023-09-27 | | 最終更新日 | 2023-12-13 | | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | | 主引用文献 | Structural basis for recruitment of TASL by SLC15A4 in human endolysosomal TLR signaling.
Nat Commun, 14, 2023
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8J2F
 | | Human neutral shpingomyelinase | | 分子名称: | HEPTANE, MAGNESIUM ION, Sphingomyelin phosphodiesterase 2, ... | | 著者 | Zhang, S.S. | | 登録日 | 2023-04-14 | | 公開日 | 2023-12-06 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (3.07 Å) | | 主引用文献 | Molecular basis for the catalytic mechanism of human neutral sphingomyelinases 1 (hSMPD2).
Nat Commun, 14, 2023
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7BXU
 | | CLC-7/Ostm1 membrane protein complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, H(+)/Cl(-) exchange transporter 7, Osteopetrosis-associated transmembrane protein 1 | | 著者 | Zhang, S.S, Yang, M.J. | | 登録日 | 2020-04-20 | | 公開日 | 2020-09-16 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Molecular insights into the human CLC-7/Ostm1 transporter.
Sci Adv, 6, 2020
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7EKM
 | | Mitochondrial outer membrane protein | | 分子名称: | ATP-binding cassette sub-family B member 6, mitochondrial | | 著者 | Zhang, S.S. | | 登録日 | 2021-04-05 | | 公開日 | 2021-08-25 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Molecular insights into the human ABCB6 transporter.
Cell Discov, 7, 2021
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7EKL
 | | Mitochondrial outer membrane protein | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family B member 6, MAGNESIUM ION | | 著者 | Zhang, S.S. | | 登録日 | 2021-04-05 | | 公開日 | 2021-08-25 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Molecular insights into the human ABCB6 transporter.
Cell Discov, 7, 2021
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7FJM
 | | Cryo EM structure of lysosomal ATPase | | 分子名称: | Polyamine-transporting ATPase 13A2 | | 著者 | Zhang, S.S. | | 登録日 | 2021-08-04 | | 公開日 | 2023-03-08 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Cryo-EM structures and transport mechanism of human P5B type ATPase ATP13A2.
Cell Discov, 7, 2021
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7FJQ
 | | Cryo EM structure of lysosomal ATPase | | 分子名称: | Polyamine-transporting ATPase 13A2, SPERMINE | | 著者 | Zhang, S.S. | | 登録日 | 2021-08-04 | | 公開日 | 2023-03-08 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Cryo-EM structures and transport mechanism of human P5B type ATPase ATP13A2.
Cell Discov, 7, 2021
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7FJP
 | | Cryo EM structure of lysosomal ATPase | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... | | 著者 | Zhang, S.S. | | 登録日 | 2021-08-04 | | 公開日 | 2023-03-08 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Cryo-EM structures and transport mechanism of human P5B type ATPase ATP13A2.
Cell Discov, 7, 2021
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7DWB
 | | Human Pannexin1 model | | 分子名称: | Pannexin-1 | | 著者 | Zhang, S.S, Yang, M.J. | | 登録日 | 2021-01-17 | | 公開日 | 2021-05-26 | | 実験手法 | ELECTRON MICROSCOPY (3.15 Å) | | 主引用文献 | Structure of the full-length human Pannexin1 channel and insights into its role in pyroptosis.
Cell Discov, 7, 2021
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7E6Q
 | | Crystal structure of influenza A virus neuraminidase N5 complexed with 4'-phenyl-1,2,3-triazolylated oseltamivir carboxylate | | 分子名称: | (3R,4R,5S)-4-acetamido-3-pentan-3-yloxy-5-(4-phenyl-1,2,3-triazol-1-yl)cyclohexene-1-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Wang, P.F, Babayemi, O.O, Li, C.N, Fu, L.F, Zhang, S.S, Qi, J.X, Lv, X, Li, X.B. | | 登録日 | 2021-02-23 | | 公開日 | 2021-03-17 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure-based design of 5'-substituted 1,2,3-triazolylated oseltamivir derivatives as potent influenza neuraminidase inhibitors.
Rsc Adv, 11, 2021
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