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PDB: 726 件

5XE5
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Discovery and structural analysis of a phloretin hydrolase from the opportunistic pathogen Mycobacterium abscessus
分子名称: 1,2-ETHANEDIOL, MAGNESIUM ION, phloretin hydrolase
著者He, Y.X, Han, J.T, Jia, W.J, Zhang, Z.
登録日2017-04-01
公開日2018-05-02
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Discovery and structural analysis of a phloretin hydrolase from the opportunistic human pathogen Mycobacterium abscessus.
FEBS J., 2019
8GSB
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BU of 8gsb by Molmil
SARS-COV-2 BA.1 Spike incomplex with VacBB-665
分子名称: Light chain of VacBB-665, Spike protein S1, heavy chain of VacBB-665
著者Liu, C.C, Ju, B, Shen, S.L, Zhang, Z.
登録日2022-09-05
公開日2023-09-06
実験手法ELECTRON MICROSCOPY (3.99 Å)
主引用文献Complex of SARS-COV-2 spike BA.1 and VacBB-665
To Be Published
1RYU
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BU of 1ryu by Molmil
Solution Structure of the SWI1 ARID
分子名称: SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin subfamily F member 1
著者Kim, S, Zhang, Z, Upchurch, S, Isern, N, Chen, Y.
登録日2003-12-22
公開日2004-05-25
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure and DNA-binding sites of the SWI1 AT-rich interaction domain (ARID) suggest determinants for sequence-specific DNA recognition.
J.Biol.Chem., 279, 2004
1RXD
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Crystal structure of human protein tyrosine phosphatase 4A1
分子名称: protein tyrosine phosphatase type IVA, member 1; Protein tyrosine phosphatase IVA1
著者Sun, J.P, Fedorov, A.A, Almo, S.C, Zhang, Z.Y, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2003-12-18
公開日2004-12-28
最終更新日2021-02-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural genomics of protein phosphatases.
J.STRUCT.FUNCT.GENOM., 8, 2007
7K56
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Structure of VCP dodecamer purified from H1299 cells
分子名称: Transitional endoplasmic reticulum ATPase
著者Yu, G, Bai, Y, Li, K, Jiang, W, Zhang, Z.Y.
登録日2020-09-16
公開日2021-10-13
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Cryo-electron microscopy structures of VCP/p97 reveal a new mechanism of oligomerization regulation.
Iscience, 24, 2021
7K59
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Structure of apo VCP hexamer generated from bacterially recombinant VCP/p97
分子名称: Transitional endoplasmic reticulum ATPase
著者Yu, G, Bai, Y, Li, K, Jiang, W, Zhang, Z.Y.
登録日2020-09-16
公開日2021-10-13
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Cryo-electron microscopy structures of VCP/p97 reveal a new mechanism of oligomerization regulation.
Iscience, 24, 2021
7K57
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Structure of apo VCP dodecamer generated from bacterially recombinant VCP/p97
分子名称: Transitional endoplasmic reticulum ATPase
著者Yu, G, Bai, Y, Li, K, Jiang, W, Zhang, Z.Y.
登録日2020-09-16
公開日2021-10-13
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Cryo-electron microscopy structures of VCP/p97 reveal a new mechanism of oligomerization regulation.
Iscience, 24, 2021
7E8C
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SARS-CoV-2 S-6P in complex with 9 Fabs
分子名称: 368-2 H, 368-2 L, 604 H, ...
著者Du, S, Xiao, J, Zhang, Z.
登録日2021-03-01
公開日2021-06-09
最終更新日2021-07-14
実験手法ELECTRON MICROSCOPY (3.16 Å)
主引用文献Humoral immune response to circulating SARS-CoV-2 variants elicited by inactivated and RBD-subunit vaccines.
Cell Res., 31, 2021
5YB1
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BU of 5yb1 by Molmil
Structure and function of human serum albumin-metal agent complex
分子名称: PALMITIC ACID, Serum albumin, ~{N},~{N},12-trimethyl-3$l^{3}-thia-1$l^{4},5,6$l^{4}-triaza-2$l^{3}-cupratricyclo[6.4.0.0^{2,6}]dodeca-1(8),3,6,9,11-pentaen-4-amine
著者Yang, F, Wang, T, Wang, J, Gou, Y, Zhang, Z.L.
登録日2017-09-02
公開日2018-09-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.616 Å)
主引用文献Developing an Anticancer Copper(II) Multitarget Pro-Drug Based on the His146 Residue in the IB Subdomain of Modified Human Serum Albumin.
Mol. Pharm., 15, 2018
1SG0
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BU of 1sg0 by Molmil
Crystal structure analysis of QR2 in complex with resveratrol
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, NRH dehydrogenase [quinone] 2, RESVERATROL, ...
著者Buryanovskyy, L, Fu, Y, Boyd, M, Ma, Y, Tsieh, T.C, Wu, J.M, Zhang, Z.
登録日2004-02-22
公開日2005-01-25
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of quinone reductase 2 in complex with resveratrol
Biochemistry, 43, 2004
4L07
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Crystal structure of the maleamate amidase Ami from Pseudomonas putida S16
分子名称: GLYCEROL, Hydrolase, isochorismatase family, ...
著者Chen, D.D, Lu, Y, Zhang, Z, Wu, G, Xu, P.
登録日2013-05-30
公開日2014-07-16
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural insights into the specific recognition of N-heterocycle biodenitrogenation-derived substrates by microbial amide hydrolases.
Mol.Microbiol., 91, 2014
4FQ7
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Crystal structure of the maleate isomerase Iso from Pseudomonas putida S16
分子名称: Maleate cis-trans isomerase
著者Lu, Y, Chen, D, Zhang, Z, Li, Q, Wu, G, Xu, P.
登録日2012-06-25
公開日2013-07-24
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural and computational studies of the maleate isomerase from Pseudomonas putida S16 reveal a breathing motion wrapping the substrate inside.
Mol.Microbiol., 87, 2013
4FQ5
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Crystal structure of the maleate isomerase Iso(C200A) from Pseudomonas putida S16 with maleate
分子名称: MALEIC ACID, Maleate cis-trans isomerase
著者Lu, Y, Chen, D, Zhang, Z, Li, Q, Wu, G, Xu, P.
登録日2012-06-25
公開日2013-07-24
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural and computational studies of the maleate isomerase from Pseudomonas putida S16 reveal a breathing motion wrapping the substrate inside.
Mol.Microbiol., 87, 2013
5UAK
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BU of 5uak by Molmil
Dephosphorylated, ATP-free human cystic fibrosis transmembrane conductance regulator (CFTR)
分子名称: Cystic fibrosis transmembrane conductance regulator
著者Liu, F, Zhang, Z, Chen, J.
登録日2016-12-19
公開日2017-01-18
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.87 Å)
主引用文献Molecular Structure of the Human CFTR Ion Channel.
Cell, 169, 2017
1PXH
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Crystal structure of protein tyrosine phosphatase 1B with potent and selective bidentate inhibitor compound 2
分子名称: ACETIC ACID, MAGNESIUM ION, N-{1-[5-(1-CARBAMOYL-2-MERCAPTO-ETHYLCARBAMOYL)-PENTYLCARBAMOYL]-2-[4-(DIFLUORO-PHOSPHONO-METHYL)-PHENYL]-ETHYL}-3-{2-[4-(DIFLUORO-PHOSPHONO-METHYL)-PHENYL]-ACETYLAMINO}-SUCCINAMIC ACID, ...
著者Sun, J.P, Fedorov, A, Lee, S.Y, Guo, X.L, Shen, K, Lawrence, D.S, Almo, S.C, Zhang, Z.Y.
登録日2003-07-04
公開日2003-08-12
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal structure of PTP1B complexed with a potent and selective bidentate inhibitor.
J.Biol.Chem., 278, 2003
6CEB
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Insulin Receptor ectodomain in complex with two insulin molecules - C1 symmetry
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Scapin, G, Dandey, V.P, Zhang, Z, Strickland, C, Potter, C.S, Carragher, B.
登録日2018-02-11
公開日2018-03-14
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Structure of the insulin receptor-insulin complex by single-particle cryo-EM analysis.
Nature, 556, 2018
1RDP
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Cholera Toxin B-Pentamer Complexed With Bivalent Nitrophenol-Galactoside Ligand BV3
分子名称: 1,3-BIS-([[3-(4-{3-[3-NITRO-5-(GALACTOPYRANOSYLOXY)-BENZOYLAMINO]-PROPYL}-PIPERAZIN-1-YL)-PROPYLAMINO-3,4-DIOXO-CYCLOBU TENYL]-AMINO-ETHYL]-AMINO-CARBONYLOXY)-2-AMINO-PROPANE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, TRIETHYLENE GLYCOL, ...
著者Pickens, J.C, Mitchell, D.D, Liu, J, Tan, X, Zhang, Z, Verlinde, C.L, Hol, W.G, Fan, E.
登録日2003-11-05
公開日2004-10-26
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Nonspanning bivalent ligands as improved surface receptor binding inhibitors of the cholera toxin B pentamer.
Chem.Biol., 11, 2004
5Z0A
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ST0452(Y97N)-GlcNAc binding form
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Dual sugar-1-phosphate nucleotidylyltransferase
著者Honda, Y, Nakano, S, Ito, S, Dadashipour, M, Zhang, Z, Kawarabayasi, Y.
登録日2017-12-19
公開日2018-10-31
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Improvement of ST0452N-Acetylglucosamine-1-Phosphate Uridyltransferase Activity by the Cooperative Effect of Two Single Mutations Identified through Structure-Based Protein Engineering
Appl. Environ. Microbiol., 84, 2018
1RF2
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Cholera Toxin B-Pentamer Complexed With Bivalent Nitrophenol-Galactoside Ligand BV4
分子名称: 1,3-BIS-([3-[3-[3-(4-{3-[3-NITRO-5-(GALACTOPYRANOSYLOXY)-BENZOYLAMINO]-PROPYL}-PIPERAZIN-1-YL)-PROPYLAMINO-3,4-DIOXO-CYCLOBUTENYL]-AMINO-PROPOXY-ETHOXY-ETHOXY]-PROPYL-]AMINO-CARBONYLOXY)-2-AMINO-PROPANE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, TRIETHYLENE GLYCOL, ...
著者Pickens, J.C, Mitchell, D.D, Liu, J, Tan, X, Zhang, Z, Verlinde, C.L, Hol, W.G, Fan, E.
登録日2003-11-07
公開日2004-10-26
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Nonspanning bivalent ligands as improved surface receptor binding inhibitors of the cholera toxin B pentamer.
Chem.Biol., 11, 2004
7DMN
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Crystal structure of two pericyclases catalyzing [4+2] cycloaddition
分子名称: Diels-Alderase fsa2, GLYCEROL
著者Chi, C.B, Wang, Z.D, Liu, T, Zhang, Z.Y, Ma, M.
登録日2020-12-04
公開日2021-10-06
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structures of Fsa2 and Phm7 Catalyzing [4 + 2] Cycloaddition Reactions with Reverse Stereoselectivities in Equisetin and Phomasetin Biosynthesis.
Acs Omega, 6, 2021
1RD9
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Cholera Toxin B-Pentamer Complexed With Bivalent Nitrophenol-Galactoside Ligand BV2
分子名称: 1,3-BIS-([3-(4-{3-[3-NITRO-5-(GALACTOPYRANOSYLOXY)-BENZOYLAMINO]-PROPYL}-PIPERAZIN-1-YL)-PROPYL-AMINO]-CARBONYLOXY)-2-AMINO-PROPANE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, HEXAETHYLENE GLYCOL, ...
著者Pickens, J.C, Mitchell, D.D, Liu, J, Tan, X, Zhang, Z, Verlinde, C.L, Hol, W.G, Fan, E.
登録日2003-11-05
公開日2004-10-26
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.44 Å)
主引用文献Nonspanning bivalent ligands as improved surface receptor binding inhibitors of the cholera toxin B pentamer.
Chem.Biol., 11, 2004
2FOT
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Crystal structure of the complex between calmodulin and alphaII-spectrin
分子名称: CALCIUM ION, Calmodulin, alpha-II spectrin Spectrin
著者Simonovic, M, Zhang, Z, Cianci, C.D, Steitz, T.A, Morrow, J.S.
登録日2006-01-13
公開日2006-09-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structure of the calmodulin alphaII-spectrin complex provides insight into the regulation of cell plasticity.
J.Biol.Chem., 281, 2006
6CE7
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Insulin Receptor ectodomain in complex with one insulin molecule
分子名称: Insulin A chain, Insulin B chain, Insulin receptor, ...
著者Scapin, G, Dandey, V.P, Zhang, Z, Strickland, C, Potter, C.S, Carragher, B.
登録日2018-02-11
公開日2018-03-14
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (7.4 Å)
主引用文献Structure of the insulin receptor-insulin complex by single-particle cryo-EM analysis.
Nature, 556, 2018
2FYS
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Crystal structure of Erk2 complex with KIM peptide derived from MKP3
分子名称: Dual specificity protein phosphatase 6, Mitogen-activated protein kinase 1
著者Liu, S, Sun, J.P, Zhou, B, Zhang, Z.Y.
登録日2006-02-08
公開日2006-04-11
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis of docking interactions between ERK2 and MAP kinase phosphatase 3
Proc.Natl.Acad.Sci.Usa, 103, 2006
6CE9
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Insulin Receptor ectodomain in complex with two insulin molecules
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Scapin, G, Dandey, V.P, Zhang, Z, Strickland, C, Potter, C.S, Carragher, B.
登録日2018-02-11
公開日2018-03-14
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Structure of the insulin receptor-insulin complex by single-particle cryo-EM analysis.
Nature, 556, 2018

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