1WET
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![BU of 1wet by Molmil](/molmil-images/mine/1wet) | STRUCTURE OF THE PURR-GUANINE-PURF OPERATOR COMPLEX | Descriptor: | DNA (5'-D(*AP*AP*CP*GP*AP*AP*AP*AP*CP*GP*TP*TP*TP*TP*CP*GP*T )-3'), GUANINE, PROTEIN (PURINE REPRESSOR) | Authors: | Schumacher, M.A, Glasfeld, A, Zalkin, H, Brennan, R.G. | Deposit date: | 1997-04-27 | Release date: | 1997-11-21 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The X-ray structure of the PurR-guanine-purF operator complex reveals the contributions of complementary electrostatic surfaces and a water-mediated hydrogen bond to corepressor specificity and binding affinity. J.Biol.Chem., 272, 1997
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1VPW
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![BU of 1vpw by Molmil](/molmil-images/mine/1vpw) | STRUCTURE OF THE PURR MUTANT, L54M, BOUND TO HYPOXANTHINE AND PURF OPERATOR DNA | Descriptor: | DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*AP*CP*GP*TP*TP*TP*GP*CP*GP*T )-3'), HYPOXANTHINE, PURINE REPRESSOR | Authors: | Arvidson, D.N, Lu, F, Faber, C, Zalkin, H, Brennan, R.G. | Deposit date: | 1998-02-27 | Release date: | 1998-06-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The structure of PurR mutant L54M shows an alternative route to DNA kinking. Nat.Struct.Biol., 5, 1998
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2XCL
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![BU of 2xcl by Molmil](/molmil-images/mine/2xcl) | |
2XD4
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![BU of 2xd4 by Molmil](/molmil-images/mine/2xd4) | |
1BDH
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![BU of 1bdh by Molmil](/molmil-images/mine/1bdh) | PURINE REPRESSOR MUTANT-HYPOXANTHINE-PALINDROMIC OPERATOR COMPLEX | Descriptor: | DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*AP*CP*GP*TP*TP*TP*GP*CP*GP*T )-3'), HYPOXANTHINE, PROTEIN (PURINE REPRESSOR) | Authors: | Glasfeld, A, Schumacher, M.A, Choi, K.Y, Zalkin, H, Brennan, R.G. | Deposit date: | 1996-07-25 | Release date: | 1997-04-21 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | A Positively Charged Residue Bound in the Minor Groove Does not Alter the Bending of a DNA Duplex J.Am.Chem.Soc., 118, 1996
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1BDI
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![BU of 1bdi by Molmil](/molmil-images/mine/1bdi) | PURINE REPRESSOR MUTANT-HYPOXANTHINE-PALINDROMIC OPERATOR COMPLEX | Descriptor: | DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*AP*CP*GP*TP*TP*TP*GP*CP*GP*T )-3'), HYPOXANTHINE, PROTEIN (PURINE REPRESSOR) | Authors: | Glasfeld, A, Schumacher, M.A, Choi, K.Y, Zalkin, H, Brennan, R.G. | Deposit date: | 1996-07-25 | Release date: | 1997-04-21 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | A Positively Charged Residue Bound in the Minor Groove Does not Alter the Bending of a DNA Duplex J.Am.Chem.Soc., 118, 1996
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2PUE
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![BU of 2pue by Molmil](/molmil-images/mine/2pue) | CRYSTAL STRUCTURE OF THE LACI FAMILY MEMBER, PURR, BOUND TO DNA: MINOR GROOVE BINDING BY ALPHA HELICES | Descriptor: | ADENINE, DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*AP*CP*GP*TP*TP*TP*GP*CP*GP*T )-3'), PROTEIN (PURINE REPRESSOR ) | Authors: | Lu, F, Schumacher, M.A, Arvidson, D.N, Haldimann, A, Wanner, B.L, Zalkin, H, Brennan, R.G. | Deposit date: | 1997-10-04 | Release date: | 1998-05-06 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure-based redesign of corepressor specificity of the Escherichia coli purine repressor by substitution of residue 190. Biochemistry, 37, 1998
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2PUB
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![BU of 2pub by Molmil](/molmil-images/mine/2pub) | CRYSTAL STRUCTURE OF THE LACI FAMILY MEMBER, PURR, BOUND TO DNA: MINOR GROOVE BINDING BY ALPHA HELICES | Descriptor: | ADENINE, DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*AP*CP*GP*TP*TP*TP*GP*CP*GP*T )-3'), PURINE REPRESSOR | Authors: | Schumacher, R.G, Choi, K.Y, Zalkin, H, Brennan, M.A. | Deposit date: | 1997-10-04 | Release date: | 1998-05-06 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of LacI member, PurR, bound to DNA: minor groove binding by alpha helices. Science, 266, 1994
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2PUG
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![BU of 2pug by Molmil](/molmil-images/mine/2pug) | CRYSTAL STRUCTURE OF THE LACI FAMILY MEMBER, PURR, BOUND TO DNA: MINOR GROOVE BINDING BY ALPHA HELICES | Descriptor: | DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*AP*CP*GP*TP*TP*TP*GP*CP*GP*T )-3'), HYPOXANTHINE, PROTEIN (PURINE REPRESSOR) | Authors: | Lu, F, Schumacher, M.A, Arvidson, D.N, Haldimann, A, Wanner, B.L, Zalkin, H, Brennan, R.G. | Deposit date: | 1997-10-04 | Release date: | 1998-05-06 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure-based redesign of corepressor specificity of the Escherichia coli purine repressor by substitution of residue 190. Biochemistry, 37, 1998
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2PUD
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![BU of 2pud by Molmil](/molmil-images/mine/2pud) | CRYSTAL STRUCTURE OF THE LACI FAMILY MEMBER, PURR, BOUND TO DNA: MINOR GROOVE BINDING BY ALPHA HELICES | Descriptor: | DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*AP*CP*GP*TP*TP*TP*GP*CP*GP*T )-3'), HYPOXANTHINE, PROTEIN (PURINE REPRESSOR) | Authors: | Schumacher, M.A, Choi, K.Y, Zalkin, H, Brennan, R.G. | Deposit date: | 1997-10-04 | Release date: | 1998-05-06 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of LacI member, PurR, bound to DNA: minor groove binding by alpha helices. Science, 266, 1994
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2PUF
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![BU of 2puf by Molmil](/molmil-images/mine/2puf) | CRYSTAL STRUCTURE OF THE LACI FAMILY MEMBER, PURR, BOUND TO DNA: MINOR GROOVE BINDING BY ALPHA HELICES | Descriptor: | DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*AP*CP*GP*TP*TP*TP*GP*CP*GP*T )-3'), GUANINE, PROTEIN (PURINE REPRESSOR) | Authors: | Lu, F, Schumacher, M.A, Arvidson, D.N, Haldimann, A, Wanner, B.L, Zalkin, H, Brennan, R.G. | Deposit date: | 1997-10-04 | Release date: | 1998-05-06 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure-based redesign of corepressor specificity of the Escherichia coli purine repressor by substitution of residue 190. Biochemistry, 37, 1998
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2PUA
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![BU of 2pua by Molmil](/molmil-images/mine/2pua) | CRYSTAL STRUCTURE OF THE LACI FAMILY MEMBER, PURR, BOUND TO DNA: MINOR GROOVE BINDING BY ALPHA HELICES | Descriptor: | 6-METHYLPURINE, DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*AP*CP*GP*TP*TP*TP*GP*CP*GP*T )-3'), PURINE REPRESSOR | Authors: | Schumacher, R.G, Choi, K.Y, Zalkin, H, Brennan, M.A. | Deposit date: | 1997-10-04 | Release date: | 1998-05-06 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of LacI member, PurR, bound to DNA: minor groove binding by alpha helices. Science, 266, 1994
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2PUC
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![BU of 2puc by Molmil](/molmil-images/mine/2puc) | CRYSTAL STRUCTURE OF THE LACI FAMILY MEMBER, PURR, BOUND TO DNA: MINOR GROOVE BINDING BY ALPHA HELICES | Descriptor: | DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*AP*CP*GP*TP*TP*TP*GP*CP*GP*T )-3'), GUANINE, PROTEIN (PURINE REPRESSOR) | Authors: | Schumacher, M.A, Choi, K.Y, Zalkin, H, Brennan, R.G. | Deposit date: | 1997-10-04 | Release date: | 1998-05-06 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of LacI member, PurR, bound to DNA: minor groove binding by alpha helices. Science, 266, 1994
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1DBQ
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![BU of 1dbq by Molmil](/molmil-images/mine/1dbq) | DNA-BINDING REGULATORY PROTEIN | Descriptor: | MAGNESIUM ION, PURINE REPRESSOR | Authors: | Schumacher, M.A, Choi, K.Y, Lu, F, Zalkin, H, Brennan, R.G. | Deposit date: | 1996-02-13 | Release date: | 1996-12-07 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Mechanism of corepressor-mediated specific DNA binding by the purine repressor. Cell(Cambridge,Mass.), 83, 1995
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1JFS
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![BU of 1jfs by Molmil](/molmil-images/mine/1jfs) | PURINE REPRESSOR MUTANT-HYPOXANTHINE-PURF OPERATOR COMPLEX | Descriptor: | 5'-D(*TP*AP*CP*GP*CP*AP*AP*AP*CP*GP*TP*TP*TP*GP*CP*GP*T)-3', HYPOXANTHINE, PURINE NUCLEOTIDE SYNTHESIS REPRESSOR | Authors: | Huffman, J.L, Lu, F, Zalkin, H, Brennan, R.G. | Deposit date: | 2001-06-21 | Release date: | 2002-02-08 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Role of residue 147 in the gene regulatory function of the Escherichia coli purine repressor. Biochemistry, 41, 2002
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1JFT
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![BU of 1jft by Molmil](/molmil-images/mine/1jft) | PURINE REPRESSOR MUTANT-HYPOXANTHINE-PURF OPERATOR COMPLEX | Descriptor: | 5'-D(*TP*AP*CP*GP*CP*AP*AP*AP*CP*GP*TP*TP*TP*GP*CP*GP*T)-3', HYPOXANTHINE, PHOSPHATE ION, ... | Authors: | Huffman, J.L, Lu, F, Zalkin, H, Brennan, R.G. | Deposit date: | 2001-06-21 | Release date: | 2002-02-08 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Role of residue 147 in the gene regulatory function of the Escherichia coli purine repressor. Biochemistry, 41, 2002
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1JH9
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![BU of 1jh9 by Molmil](/molmil-images/mine/1jh9) | PURINE REPRESSOR MUTANT-HYPOXANTHINE-PURF OPERATOR COMPLEX | Descriptor: | 5'-D(*AP*AP*CP*GP*AP*AP*AP*AP*CP*GP*TP*TP*TP*TP*CP*GP*T)-3', HYPOXANTHINE, PHOSPHATE ION, ... | Authors: | Huffman, J.L, Lu, F, Zalkin, H, Brennan, R.G. | Deposit date: | 2001-06-27 | Release date: | 2002-02-08 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Role of residue 147 in the gene regulatory function of the Escherichia coli purine repressor. Biochemistry, 41, 2002
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1JHZ
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![BU of 1jhz by Molmil](/molmil-images/mine/1jhz) | Purine Repressor Mutant Corepressor Binding Domain Structure | Descriptor: | MAGNESIUM ION, PURINE NUCLEOTIDE SYNTHESIS REPRESSOR | Authors: | Huffman, J.L, Lu, F, Zalkin, H, Brennan, R.G. | Deposit date: | 2001-06-28 | Release date: | 2002-02-08 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Role of residue 147 in the gene regulatory function of the Escherichia coli purine repressor. Biochemistry, 41, 2002
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1O57
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![BU of 1o57 by Molmil](/molmil-images/mine/1o57) | CRYSTAL STRUCTURE OF THE PURINE OPERON REPRESSOR OF BACILLUS SUBTILIS | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HEXAETHYLENE GLYCOL, NONAETHYLENE GLYCOL, ... | Authors: | Sinha, S.C, Krahn, J, Shin, B.S, Tomchick, D.R, Zalkin, H, Smith, J.L. | Deposit date: | 2003-04-20 | Release date: | 2003-08-26 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The Purine Repressor of Bacillus Subtilis: A Novel Combination of Domains Adapted for Transcription Regulation J.Bacteriol., 185, 2003
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1P4A
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![BU of 1p4a by Molmil](/molmil-images/mine/1p4a) | Crystal Structure of the PurR complexed with cPRPP | Descriptor: | 1-ALPHA-PYROPHOSPHORYL-2-ALPHA,3-ALPHA-DIHYDROXY-4-BETA-CYCLOPENTANE-METHANOL-5-PHOSPHATE, Pur operon repressor | Authors: | Bera, A.K, Zhu, J, Zalkin, H, Smith, J.L. | Deposit date: | 2003-04-22 | Release date: | 2003-12-09 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.22 Å) | Cite: | Functional dissection of the Bacillus subtilis pur operator site. J.Bacteriol., 185, 2003
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1PNR
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![BU of 1pnr by Molmil](/molmil-images/mine/1pnr) | PURINE REPRESSOR-HYPOXANTHINE-PURF-OPERATOR COMPLEX | Descriptor: | DNA (5'-D(*AP*AP*CP*GP*AP*AP*AP*AP*CP*GP*TP*TP*TP*TP*CP*GP*T )-3'), HYPOXANTHINE, PROTEIN (PURINE REPRESSOR) | Authors: | Schumacher, M.A, Choi, K.Y, Zalkin, H, Brennan, R.G. | Deposit date: | 1995-03-29 | Release date: | 1995-11-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of LacI member, PurR, bound to DNA: minor groove binding by alpha helices. Science, 266, 1994
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1QD9
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![BU of 1qd9 by Molmil](/molmil-images/mine/1qd9) | Bacillus subtilis YABJ | Descriptor: | ACETIC ACID, ETHYL MERCURY ION, MERCURY (II) ION, ... | Authors: | Smith, J.L, Sinha, S, Rappu, P, Lange, S.C, Mantsala, P, Zalkin, H. | Deposit date: | 1999-07-09 | Release date: | 1999-11-26 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of Bacillus subtilis YabJ, a purine regulatory protein and member of the highly conserved YjgF family. Proc.Natl.Acad.Sci.USA, 96, 1999
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