4JUJ
| Crystal structure of 1918 pandemic influenza virus hemagglutinin mutant D225G complexed with human receptor analogue LSTc | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Zhang, W, Shi, Y, Qi, J, Gao, F, Li, Q, Fan, Z, Yan, J, Gao, G.F. | Deposit date: | 2013-03-25 | Release date: | 2013-05-01 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.013 Å) | Cite: | Molecular basis of the receptor binding specificity switch of the hemagglutinins from both the 1918 and 2009 pandemic influenza A viruses by a D225G substitution J.Virol., 87, 2013
|
|
4JUH
| Crystal structure of 1918 pandemic influenza virus hemagglutinin mutant D225G complexed with avian receptor analogue LSTa | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Zhang, W, Shi, Y, Qi, J, Gao, F, Li, Q, Fan, Z, Yan, J, Gao, G.F. | Deposit date: | 2013-03-24 | Release date: | 2013-05-01 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.805 Å) | Cite: | Molecular basis of the receptor binding specificity switch of the hemagglutinins from both the 1918 and 2009 pandemic influenza A viruses by a D225G substitution J.Virol., 87, 2013
|
|
4K67
| Structure of an airborne transmissible avian influenza H5 hemagglutinin mutant from the influenza virus A/Indonesia/5/2005 complexed with human receptor analog LSTc | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose, ... | Authors: | Zhang, W, Shi, Y, Lu, X, Shu, Y, Gao, G.F. | Deposit date: | 2013-04-15 | Release date: | 2013-05-22 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | An airborne transmissible avian influenza H5 hemagglutinin seen at the atomic level. Science, 340, 2013
|
|
4K66
| Structure of an airborne transmissible avian influenza H5 hemagglutinin mutant from the influenza virus A/Indonesia/5/2005 complexed with avian receptor analog LSTa | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose | Authors: | Zhang, W, Shi, Y, Lu, X, Shu, Y, Qi, J, Gao, G.F. | Deposit date: | 2013-04-15 | Release date: | 2013-05-22 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.005 Å) | Cite: | An airborne transmissible avian influenza H5 hemagglutinin seen at the atomic level. Science, 340, 2013
|
|
4K62
| Structure of an avian influenza H5 hemagglutinin from the influenza virus A/Indonesia/5/2005 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin | Authors: | Zhang, W, Shi, Y, Lu, X, Shu, Y, Qi, J, Gao, G.F. | Deposit date: | 2013-04-15 | Release date: | 2013-05-22 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.502 Å) | Cite: | An airborne transmissible avian influenza H5 hemagglutinin seen at the atomic level. Science, 340, 2013
|
|
4K63
| Structure of an avian influenza H5 hemagglutinin from the influenza virus complexed with avian receptor analog LSTa | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose, ... | Authors: | Zhang, W, Shi, Y, Lu, X, Shu, Y, Qi, J, Gao, G.F. | Deposit date: | 2013-04-15 | Release date: | 2013-05-22 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | An airborne transmissible avian influenza H5 hemagglutinin seen at the atomic level. Science, 340, 2013
|
|
4K65
| Structure of an airborne transmissible avian influenza H5 hemagglutinin mutant from the influenza virus A/Indonesia/5/2005 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin | Authors: | Zhang, W, Shi, Y, Lu, X, Shu, Y, Qi, J, Gao, G.F. | Deposit date: | 2013-04-15 | Release date: | 2013-05-22 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | An airborne transmissible avian influenza H5 hemagglutinin seen at the atomic level. Science, 340, 2013
|
|
4K64
| Structure of an avian influenza H5 hemagglutinin from the influenza virus complexed with human receptor analog LSTc | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose | Authors: | Zhang, W, Shi, Y, Lu, X, Shu, Y, Qi, J, Gao, G.F. | Deposit date: | 2013-04-15 | Release date: | 2013-05-22 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.604 Å) | Cite: | An airborne transmissible avian influenza H5 hemagglutinin seen at the atomic level. Science, 340, 2013
|
|
5WCO
| Matrix Protein (M1) of Infectious Salmon Anaemia Virus | Descriptor: | NS2 | Authors: | Zhang, W, Zheng, W, Toh, Y, Betancourt, M.A, Tu, J, Fan, Y, Vakharia, V, Liu, J, McNew, J.A, Jin, M, Tao, Y.J. | Deposit date: | 2017-07-01 | Release date: | 2017-08-16 | Last modified: | 2019-12-11 | Method: | X-RAY DIFFRACTION (2.604 Å) | Cite: | Crystal structure of an orthomyxovirus matrix protein reveals mechanisms for self-polymerization and membrane association. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
5ZHY
| Structural characterization of the HCoV-229E fusion core | Descriptor: | Spike glycoprotein | Authors: | Zhang, W, Zheng, Q, Yan, M, Chen, X, Yang, H, Zhou, W, Rao, Z. | Deposit date: | 2018-03-13 | Release date: | 2018-06-06 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.441 Å) | Cite: | Structural characterization of the HCoV-229E fusion core. Biochem. Biophys. Res. Commun., 497, 2018
|
|
5ZHZ
| Crystal structure of the apurinic/apyrimidinic endonuclease IV from Mycobacterium tuberculosis | Descriptor: | Probable endonuclease 4, SULFATE ION, ZINC ION | Authors: | Zhang, W, Xu, Y, Yan, M, Li, S, Wang, H, Yang, H, Zhou, W, Rao, Z. | Deposit date: | 2018-03-13 | Release date: | 2018-04-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.18 Å) | Cite: | Crystal structure of the apurinic/apyrimidinic endonuclease IV from Mycobacterium tuberculosis. Biochem. Biophys. Res. Commun., 498, 2018
|
|
6AZ4
| RNA hairpin complex with guanosine dinucleotide ligand G(5')ppp(5')G | Descriptor: | DIGUANOSINE-5'-TRIPHOSPHATE, RNA (32-MER), RNA (5'-R(*CP*AP*GP*CP*AP*GP*CP*AP*G)-3') | Authors: | Zhang, W, Szostak, J.W. | Deposit date: | 2017-09-09 | Release date: | 2018-02-21 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.98 Å) | Cite: | Structural Rationale for the Enhanced Catalysis of Nonenzymatic RNA Primer Extension by a Downstream Oligonucleotide. J. Am. Chem. Soc., 140, 2018
|
|
6BMD
| |
6C8D
| RNA-dGMP complex with Mg ion | Descriptor: | 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, MAGNESIUM ION, RNA (5'-R(*(LCC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*G)-3') | Authors: | Zhang, W, Szostak, J.W. | Deposit date: | 2018-01-24 | Release date: | 2018-05-30 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Crystallographic observation of nonenzymatic RNA primer extension. Elife, 7, 2018
|
|
6C8K
| RNA-activated 2-AIpG monomer complex, 30 min soaking | Descriptor: | 2-amino-1-[(R)-{[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl]-3-[(S)-{[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl]-1H-imidazol-3-ium, MAGNESIUM ION, RNA (5'-R(*(LCC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*G)-3') | Authors: | Zhang, W, Szostak, J.W. | Deposit date: | 2018-01-24 | Release date: | 2018-05-30 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.259 Å) | Cite: | Crystallographic observation of nonenzymatic RNA primer extension. Elife, 7, 2018
|
|
6C8O
| RNA-activated 2-AIpG monomer, 3h soaking | Descriptor: | 5'-O-[(R)-(2-amino-1H-imidazol-1-yl)(hydroxy)phosphoryl]guanosine, MAGNESIUM ION, RNA (5'-R(*(LCC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*GP*G)-3') | Authors: | Zhang, W, Szostak, J.W. | Deposit date: | 2018-01-25 | Release date: | 2018-05-30 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystallographic observation of nonenzymatic RNA primer extension. Elife, 7, 2018
|
|
6C8I
| RNA-activated 2-AIpG monomer complex, 5 min soaking | Descriptor: | 5'-O-[(R)-(2-amino-1H-imidazol-1-yl)(hydroxy)phosphoryl]guanosine, MAGNESIUM ION, RNA (5'-R(*(LCC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*G)-3') | Authors: | Zhang, W, Szostak, J.W. | Deposit date: | 2018-01-24 | Release date: | 2018-05-30 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Crystallographic observation of nonenzymatic RNA primer extension. Elife, 7, 2018
|
|
6C8L
| RNA-activated 2-AIpG monomer complex, 1h soaking | Descriptor: | 2-amino-1-[(R)-{[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl]-3-[(S)-{[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl]-1H-imidazol-3-ium, MAGNESIUM ION, RNA (5'-R(*(LCC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*G)-3') | Authors: | Zhang, W, Szostak, J.W. | Deposit date: | 2018-01-25 | Release date: | 2018-05-30 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Crystallographic observation of nonenzymatic RNA primer extension. Elife, 7, 2018
|
|
6C8M
| RNA-activated 2-AIpG monomer, 1.5h soaking | Descriptor: | 2-amino-1-[(R)-{[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl]-3-[(S)-{[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl]-1H-imidazol-3-ium, 5'-O-[(R)-(2-amino-1H-imidazol-1-yl)(hydroxy)phosphoryl]guanosine, RNA (5'-R(*(LCC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*G)-3'), ... | Authors: | Zhang, W, Szostak, J.W. | Deposit date: | 2018-01-25 | Release date: | 2018-05-30 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystallographic observation of nonenzymatic RNA primer extension. Elife, 7, 2018
|
|
4RC4
| |
4RBL
| Crystal structure of Ser/Thr kinase Pim1 in complex with Mitoxantrone derivatives | Descriptor: | 1,4,5,8-tetrahydroxyanthracene-9,10-dione, Serine/threonine-protein kinase pim-1 | Authors: | Zhang, W, Wan, X, Huang, N. | Deposit date: | 2014-09-12 | Release date: | 2015-03-18 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Crystal structure of Ser/Thr kinase Pim1 in complex with Mitoxantrone derivatives To be Published, 2014
|
|
4RC3
| |
4RC2
| |
7VJT
| Crystal Structure of Mtb Pks13-TE in complex with inhibitor coumestan derivative 8 | Descriptor: | 3,8-bis(oxidanyl)-7-(piperidin-1-ylmethyl)-[1]benzofuro[3,2-c]chromen-6-one, Polyketide synthase Pks13 (Termination polyketide synthase) | Authors: | Zhang, W, Wang, S.S, Yu, L.F. | Deposit date: | 2021-09-28 | Release date: | 2022-09-28 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Structure-Based Optimization of Coumestan Derivatives as Polyketide Synthase 13-Thioesterase(Pks13-TE) Inhibitors with Improved hERG Profiles for Mycobacterium tuberculosis Treatment. J.Med.Chem., 65, 2022
|
|
5ZMR
| Solution Structure of the N-terminal Domain of the Yeast Rpn5 | Descriptor: | 26S proteasome regulatory subunit RPN5 | Authors: | Zhang, W, Zhao, C, Li, H, Hu, Y, Jin, C. | Deposit date: | 2018-04-05 | Release date: | 2018-09-26 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution structure of the N-terminal domain of proteasome lid subunit Rpn5 Biochem. Biophys. Res. Commun., 504, 2018
|
|