4RC2
Crystal structure of Ser/Thr kinase Pim1 in complex with Mitoxantrone derivatives
Summary for 4RC2
Entry DOI | 10.2210/pdb4rc2/pdb |
Descriptor | Serine/threonine-protein kinase pim-1, 1-amino-5,8-dihydroxy-4-({2-[(2-hydroxyethyl)amino]ethyl}amino)anthracene-9,10-dione (2 entities in total) |
Functional Keywords | kinase, phosphorylation, signaling protein |
Biological source | Homo sapiens (human) |
Cellular location | Isoform 2: Cytoplasm. Isoform 1: Cell membrane: P11309 |
Total number of polymer chains | 1 |
Total formula weight | 33650.08 |
Authors | |
Primary citation | Zhang, W.,Wan, X.,Huang, N. Crystal structure of Ser/Thr kinase Pim1 in complex with Mitoxantrone derivatives To be Published, |
Experimental method | X-RAY DIFFRACTION (2.096 Å) |
Structure validation
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