4RC2

Crystal structure of Ser/Thr kinase Pim1 in complex with Mitoxantrone derivatives

Summary for 4RC2

• Entry DOI: 10.2210/pdb4rc2/pdb
• Descriptor: Serine/threonine-protein kinase pim-1, 1-amino-5,8-dihydroxy-4-({2-[(2-hydroxyethyl)amino]ethyl}amino)anthracene-9,10-dione (2 entities in total)
• Functional Keywords: kinase, phosphorylation, signaling protein
• Biological source: Homo sapiens (human)
• Cellular location: Isoform 2: Cytoplasm. Isoform 1: Cell membrane: P11309
• Total number of polymer chains: 1
• Total formula weight: 33650.08

Authors

Zhang, W.,Wan, X.,Huang, N. (deposition date: 2014-09-14, release date: 2015-03-18, Last modification date: 2024-11-20)

• Primary citation: Zhang, W.,Wan, X.,Huang, N.; Crystal structure of Ser/Thr kinase Pim1 in complex with Mitoxantrone derivatives; To be Published,

Experimental method

X-RAY DIFFRACTION (2.096 Å)