4RC3
Crystal structure of Ser/Thr kinase Pim1 in complex with Mitoxantrone derivatives
Summary for 4RC3
Entry DOI | 10.2210/pdb4rc3/pdb |
Related | 4I41 4RBL 4RC2 |
Descriptor | Serine/threonine-protein kinase pim-1, 1,4-dihydroxy-5,8-bis{[2-(2-hydroxyethoxy)ethyl]amino}anthracene-9,10-dione (2 entities in total) |
Functional Keywords | kinase domain, kinase, phosphorylation, signaling protein |
Biological source | Homo sapiens (human) |
Cellular location | Isoform 2: Cytoplasm. Isoform 1: Cell membrane: P11309 |
Total number of polymer chains | 1 |
Total formula weight | 33739.17 |
Authors | |
Primary citation | Zhang, W.,Wan, X.,Huang, N. Crystal structure of Ser/Thr kinase Pim1 in complex with Mitoxantrone derivatives To be Published, |
Experimental method | X-RAY DIFFRACTION (2.338 Å) |
Structure validation
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