5F52
 
 | | Erwinia chrysanthemi L-asparaginase + Aspartic acid | | Descriptor: | ASPARTIC ACID, DI(HYDROXYETHYL)ETHER, L-asparaginase | | Authors: | Nguyen, H.A, Lavie, A. | | Deposit date: | 2015-12-04 | | Release date: | 2016-04-06 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.63 Å) | | Cite: | Structural Insight into Substrate Selectivity of Erwinia chrysanthemi l-Asparaginase.
Biochemistry, 55, 2016
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5K3O
 | | Wolinella succinogenes L-asparaginase P121 and L-Aspartic acid | | Descriptor: | ASPARTIC ACID, L-asparaginase | | Authors: | Nguyen, H.A, Lave, A. | | Deposit date: | 2016-05-19 | | Release date: | 2017-03-29 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.696 Å) | | Cite: | The differential ability of asparagine and glutamine in promoting the closed/active enzyme conformation rationalizes the Wolinella succinogenes L-asparaginase substrate specificity.
Sci Rep, 7, 2017
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5K45
 | | Wolinella succinogenes L-asparaginase P121 + L-Glutamic acid | | Descriptor: | GLUTAMIC ACID, L-asparaginase | | Authors: | Nguyen, H.A, Lave, A. | | Deposit date: | 2016-05-20 | | Release date: | 2017-03-29 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.63 Å) | | Cite: | The differential ability of asparagine and glutamine in promoting the closed/active enzyme conformation rationalizes the Wolinella succinogenes L-asparaginase substrate specificity.
Sci Rep, 7, 2017
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8FOM
 | | Crystal structure of tRNA^Lys(SUU) bound to UAA codon in the ribosomal P site | | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | Authors: | Nguyen, H.A, Hoffer, E.D, Maehigashi, T, Fagan, C.E, Dunham, C.M. | | Deposit date: | 2023-01-02 | | Release date: | 2023-03-29 | | Last modified: | 2023-04-26 | | Method: | X-RAY DIFFRACTION (3.58 Å) | | Cite: | Structural basis for reduced ribosomal A-site fidelity in response to P-site codon-anticodon mismatches.
J.Biol.Chem., 299, 2023
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8FR3
 | | E. coli EF-Tu in complex with KKL-55 | | Descriptor: | 3-chloro-N-(1-propyl-1H-tetrazol-5-yl)benzamide, Elongation factor Tu, GUANOSINE-5'-DIPHOSPHATE, ... | | Authors: | Nguyen, H.A, Kuzmishin Nagy, A.B, Dunham, C.M. | | Deposit date: | 2023-01-06 | | Release date: | 2023-09-20 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.23 Å) | | Cite: | Antibiotic that inhibits trans -translation blocks binding of EF-Tu to tmRNA but not to tRNA.
Mbio, 14, 2023
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8FON
 | | Crystal structure of tRNA^Lys(SUU) bound to AUA codon in the ribosomal P site | | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | Authors: | Nguyen, H.A, Hoffer, E.D, Maehigashi, T, Fagan, C.E, Dunham, C.M. | | Deposit date: | 2023-01-02 | | Release date: | 2023-03-29 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (3.64 Å) | | Cite: | Structural basis for reduced ribosomal A-site fidelity in response to P-site codon-anticodon mismatches.
J.Biol.Chem., 299, 2023
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3L8E
 | | Crystal Structure of apo form of D,D-heptose 1.7-bisphosphate phosphatase from E. Coli | | Descriptor: | ACETIC ACID, D,D-heptose 1,7-bisphosphate phosphatase, ZINC ION | | Authors: | Nguyen, H, Peisach, E, Allen, K.N. | | Deposit date: | 2009-12-31 | | Release date: | 2010-02-02 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.64 Å) | | Cite: | Structural Determinants of Substrate Recognition in the HAD Superfamily Member d-glycero-d-manno-Heptose-1,7-bisphosphate Phosphatase (GmhB) .
Biochemistry, 49, 2010
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3L8H
 | | Crystal Structure of D,D-heptose 1.7-bisphosphate phosphatase from B. bronchiseptica complexed with magnesium and phosphate | | Descriptor: | FORMIC ACID, MAGNESIUM ION, PHOSPHATE ION, ... | | Authors: | Nguyen, H, Peisach, E, Allen, K.N. | | Deposit date: | 2009-12-31 | | Release date: | 2010-02-02 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (1.68 Å) | | Cite: | Structural Determinants of Substrate Recognition in the HAD Superfamily Member d-glycero-d-manno-Heptose-1,7-bisphosphate Phosphatase (GmhB) .
Biochemistry, 49, 2010
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1Q9W
 | | S45-18 Fab pentasaccharide bisphosphate complex | | Descriptor: | 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-4)-3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-4)-3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid, 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-4)-3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-4)-3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-6)-2-amino-2-deoxy-4-O-phosphono-alpha-D-glucopyranose-(1-6)-2-amino-2-deoxy-1-O-phosphono-alpha-D-glucopyranose, MAGNESIUM ION, ... | | Authors: | Nguyen, H.P, Seto, N.O, MacKenzie, C.R, Brade, L, Kosma, P, Brade, H, Evans, S.V. | | Deposit date: | 2003-08-26 | | Release date: | 2004-01-27 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Germline antibody recognition of distinct carbohydrate epitopes.
Nat.Struct.Biol., 10, 2003
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3L8F
 | | Crystal Structure of D,D-heptose 1.7-bisphosphate phosphatase from E. Coli complexed with magnesium and phosphate | | Descriptor: | D,D-heptose 1,7-bisphosphate phosphatase, MAGNESIUM ION, PHOSPHATE ION, ... | | Authors: | Nguyen, H, Peisach, E, Allen, K.N. | | Deposit date: | 2009-12-31 | | Release date: | 2010-02-02 | | Last modified: | 2017-11-01 | | Method: | X-RAY DIFFRACTION (1.79 Å) | | Cite: | Structural Determinants of Substrate Recognition in the HAD Superfamily Member d-glycero-d-manno-Heptose-1,7-bisphosphate Phosphatase (GmhB) .
Biochemistry, 49, 2010
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3L8G
 | | Crystal Structure of D,D-heptose 1.7-bisphosphate phosphatase from E. Coli complexed with D-glycero-D-manno-heptose 1 ,7-bisphosphate | | Descriptor: | 1,7-di-O-phosphono-L-glycero-beta-D-manno-heptopyranose, D,D-heptose 1,7-bisphosphate phosphatase, MAGNESIUM ION, ... | | Authors: | Nguyen, H, Peisach, E, Allen, K.N. | | Deposit date: | 2009-12-31 | | Release date: | 2010-02-02 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.18 Å) | | Cite: | Structural Determinants of Substrate Recognition in the HAD Superfamily Member d-glycero-d-manno-Heptose-1,7-bisphosphate Phosphatase (GmhB) .
Biochemistry, 49, 2010
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1R80
 | | Glycosyltransferase B in complex with 3-amino-acceptor analog inhibitor and uridine diphosphate | | Descriptor: | Glycoprotein-fucosylgalactoside alpha-galactosyltransferase, MANGANESE (II) ION, MERCURY (II) ION, ... | | Authors: | Nguyen, H.P, Seto, N.O.L, Cai, Y, Leinala, E.K, Borisova, S.N, Palcic, M.M, Evans, S.V. | | Deposit date: | 2003-10-22 | | Release date: | 2004-02-10 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | The influence of an intramolecular hydrogen bond in differential recognition of inhibitory acceptor analogs by human ABO(H) blood group A and B glycosyltransferases
J.Biol.Chem., 278, 2003
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1Q9O
 | | S45-18 Fab Unliganded | | Descriptor: | MAGNESIUM ION, S45-2 Fab (IgG1k) heavy chain, S45-2 Fab (IgG1k) light chain | | Authors: | Nguyen, H.P, Seto, N.O, MacKenzie, C.R, Brade, L, Kosma, P, Brade, H, Evans, S.V. | | Deposit date: | 2003-08-25 | | Release date: | 2004-01-27 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.79 Å) | | Cite: | Germline antibody recognition of distinct carbohydrate epitopes.
Nat.Struct.Biol., 10, 2003
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1R81
 | | Glycosyltransferase A in complex with 3-amino-acceptor analog inhibitor and uridine diphosphate-N-acetyl-galactose | | Descriptor: | Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase, MERCURY (II) ION, URIDINE-DIPHOSPHATE-N-ACETYLGALACTOSAMINE, ... | | Authors: | Nguyen, H.P, Seto, N.O.L, Cai, Y, Leinala, E.K, Borisova, S.N, Palcic, M.M, Evans, S.V. | | Deposit date: | 2003-10-22 | | Release date: | 2004-02-10 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | The influence of an intramolecular hydrogen bond in differential recognition of inhibitory acceptor analogs by human ABO(H) blood group A and B glycosyltransferases
J.Biol.Chem., 278, 2003
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1R7Y
 | | Glycosyltransferase A in complex with 3-amino-acceptor analog inhibitor and uridine diphosphate | | Descriptor: | Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase, MANGANESE (II) ION, MERCURY (II) ION, ... | | Authors: | Nguyen, H.P, Seto, N.O.L, Cai, Y, Leinala, E.K, Borisova, S.N, Palcic, M.M, Evans, S.V. | | Deposit date: | 2003-10-22 | | Release date: | 2004-02-10 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | The influence of an intramolecular hydrogen bond in differential recognition of inhibitory acceptor analogs by human ABO(H) blood group A and B glycosyltransferases
J.Biol.Chem., 278, 2003
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1Q9L
 | | S25-2 Fab Unliganded 2 | | Descriptor: | MAGNESIUM ION, S25-2 Fab (IgG1k) heavy chain, S25-2 Fab (IgG1k) light chain, ... | | Authors: | Nguyen, H.P, Seto, N.O, MacKenzie, C.R, Brade, L, Kosma, P, Brade, H, Evans, S.V. | | Deposit date: | 2003-08-25 | | Release date: | 2004-01-27 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.28 Å) | | Cite: | Germline antibody recognition of distinct carbohydrate epitopes.
Nat.Struct.Biol., 10, 2003
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5HW0
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5I3Z
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5I48
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1R7V
 | | Glycosyltransferase A in complex with 3-amino-acceptor analog inhibitor | | Descriptor: | Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase, MERCURY (II) ION, alpha-L-fucopyranose-(1-2)-hexyl 3-amino-3-deoxy-beta-D-galactopyranoside | | Authors: | Nguyen, H.P, Seto, N.O.L, Cai, Y, Leinala, E.K, Borisova, S.N, Palcic, M.M, Evans, S.V. | | Deposit date: | 2003-10-22 | | Release date: | 2004-02-10 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (2.09 Å) | | Cite: | The influence of an intramolecular hydrogen bond in differential recognition of inhibitory acceptor analogs by human ABO(H) blood group A and B glycosyltransferases
J.Biol.Chem., 278, 2003
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1R7X
 | | Glycosyltransferase B in complex with 3-amino-acceptor analog inhibitor | | Descriptor: | Glycoprotein-fucosylgalactoside alpha-galactosyltransferase, MERCURY (II) ION, alpha-L-fucopyranose-(1-2)-hexyl 3-amino-3-deoxy-beta-D-galactopyranoside | | Authors: | Nguyen, H.P, Seto, N.O.L, Cai, Y, Leinala, E.K, Borisova, S.N, Palcic, M.M, Evans, S.V. | | Deposit date: | 2003-10-22 | | Release date: | 2004-02-10 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (1.97 Å) | | Cite: | The influence of an intramolecular hydrogen bond in differential recognition of inhibitory acceptor analogs by human ABO(H) blood group A and B glycosyltransferases
J.Biol.Chem., 278, 2003
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5I4B
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1R7U
 | | Glycosyltransferase B in complex with 3-deoxy-acceptor analog inhibitor | | Descriptor: | Glycoprotein-fucosylgalactoside alpha-galactosyltransferase, MERCURY (II) ION, alpha-L-fucopyranose-(1-2)-hexyl 3-deoxy-beta-D-galactopyranoside | | Authors: | Nguyen, H.P, Seto, N.O.L, Cai, Y, Leinala, E.K, Borisova, S.N, Palcic, M.M, Evans, S.V. | | Deposit date: | 2003-10-22 | | Release date: | 2004-02-10 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (1.61 Å) | | Cite: | The influence of an intramolecular hydrogen bond in differential recognition of inhibitory acceptor analogs by human ABO(H) blood group A and B glycosyltransferases
J.Biol.Chem., 278, 2003
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1R82
 | | Glycosyltransferase B in complex with 3-amino-acceptor analog inhibitor, and uridine diphosphate-galactose | | Descriptor: | GALACTOSE-URIDINE-5'-DIPHOSPHATE, Glycoprotein-fucosylgalactoside alpha-galactosyltransferase, MERCURY (II) ION, ... | | Authors: | Nguyen, H.P, Seto, N.O.L, Cai, Y, Leinala, E.K, Borisova, S.N, Palcic, M.M, Evans, S.V. | | Deposit date: | 2003-10-22 | | Release date: | 2004-02-10 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | The influence of an intramolecular hydrogen bond in differential recognition of inhibitory acceptor analogs by human ABO(H) blood group A and B glycosyltransferases
J.Biol.Chem., 278, 2003
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1Q9K
 | | S25-2 Fab Unliganded 1 | | Descriptor: | MAGNESIUM ION, S25-2 Fab (IgG1k) heavy chain, S25-2 Fab (IgG1k) light chain | | Authors: | Nguyen, H.P, Seto, N.O, MacKenzie, C.R, Brade, L, Kosma, P, Brade, H, Evans, S.V. | | Deposit date: | 2003-08-25 | | Release date: | 2004-01-27 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.96 Å) | | Cite: | Germline antibody recognition of distinct carbohydrate epitopes.
Nat.Struct.Biol., 10, 2003
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