4GOY
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![BU of 4goy by Molmil](/molmil-images/mine/4goy) | The crystal structure of human fascin 1 K41A mutant | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, BROMIDE ION, CHLORIDE ION, ... | Authors: | Yang, S.Y, Huang, F.K, Huang, J, Chen, S, Jakoncic, J, Leo-Macias, A, Diaz-Avalos, R, Chen, L, Zhang, J.J, Huang, X.Y. | Deposit date: | 2012-08-20 | Release date: | 2012-11-28 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Molecular mechanism of fascin function in filopodial formation. J.Biol.Chem., 288, 2013
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4GP3
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![BU of 4gp3 by Molmil](/molmil-images/mine/4gp3) | The crystal structure of human fascin 1 K358A mutant | Descriptor: | BROMIDE ION, CHLORIDE ION, Fascin, ... | Authors: | Yang, S.Y, Huang, F.K, Huang, J, Chen, S, Jakoncic, J, Leo-Macias, A, Diaz-Avalos, R, Chen, L, Zhang, J.J, Huang, X.Y. | Deposit date: | 2012-08-20 | Release date: | 2012-11-28 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Molecular mechanism of fascin function in filopodial formation. J.Biol.Chem., 288, 2013
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4GP0
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![BU of 4gp0 by Molmil](/molmil-images/mine/4gp0) | The crystal structure of human fascin 1 R149A K150A R151A mutant | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, BROMIDE ION, ... | Authors: | Yang, S.Y, Huang, F.K, Huang, J, Chen, S, Jakoncic, J, Leo-Macias, A, Diaz-Avalos, R, Chen, L, Zhang, J.J, Huang, X.Y. | Deposit date: | 2012-08-20 | Release date: | 2012-11-28 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Molecular mechanism of fascin function in filopodial formation. J.Biol.Chem., 288, 2013
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4GOV
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![BU of 4gov by Molmil](/molmil-images/mine/4gov) | The crystal structure of human fascin 1 S39D mutant | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, BROMIDE ION, CHLORIDE ION, ... | Authors: | Yang, S.Y, Huang, F.K, Huang, J, Chen, S, Jakoncic, J, Leo-Macias, A, Diaz-Avalos, R, Chen, L, Zhang, J.J, Huang, X.Y. | Deposit date: | 2012-08-20 | Release date: | 2012-11-28 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Molecular mechanism of fascin function in filopodial formation. J.Biol.Chem., 288, 2013
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8I3Q
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![BU of 8i3q by Molmil](/molmil-images/mine/8i3q) | |
6L00
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![BU of 6l00 by Molmil](/molmil-images/mine/6l00) | |
6M6W
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![BU of 6m6w by Molmil](/molmil-images/mine/6m6w) | Crystal structure the toxin-antitoxin MntA-HpeT mutant-Y104A | Descriptor: | Toxin-antitoxin system antidote Mnt family, Toxin-antitoxin system toxin HepN family | Authors: | Ouyang, S.Y, Zhen, X.K. | Deposit date: | 2020-03-16 | Release date: | 2020-09-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.611 Å) | Cite: | Novel polyadenylylation-dependent neutralization mechanism of the HEPN/MNT toxin/antitoxin system. Nucleic Acids Res., 48, 2020
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6M6V
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![BU of 6m6v by Molmil](/molmil-images/mine/6m6v) | Crystal structure the toxin-antitoxin MntA-HepT | Descriptor: | RNA (5'-R(P*AP*AP*A)-3'), Toxin-antitoxin system antidote Mnt family, Toxin-antitoxin system toxin HepN family | Authors: | Ouyang, S.Y, Zhen, X.K. | Deposit date: | 2020-03-16 | Release date: | 2020-09-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.08 Å) | Cite: | Novel polyadenylylation-dependent neutralization mechanism of the HEPN/MNT toxin/antitoxin system. Nucleic Acids Res., 48, 2020
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6M6U
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![BU of 6m6u by Molmil](/molmil-images/mine/6m6u) | Crystal structure the toxin-antitoxin MntA-HpeT mutant-D39ED41E | Descriptor: | Toxin-antitoxin system antitoxin MntA family, Toxin-antitoxin system toxin HepN family | Authors: | Ouyang, S.Y, Zhen, X.K. | Deposit date: | 2020-03-16 | Release date: | 2020-09-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.349 Å) | Cite: | Novel polyadenylylation-dependent neutralization mechanism of the HEPN/MNT toxin/antitoxin system. Nucleic Acids Res., 48, 2020
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7BU0
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![BU of 7bu0 by Molmil](/molmil-images/mine/7bu0) | |
7BXO
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![BU of 7bxo by Molmil](/molmil-images/mine/7bxo) | Crystal structure of the toxin-antitoxin with AMP-PNP | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Toxin-antitoxin system antidote Mnt family, ... | Authors: | Ouyang, S.Y, Zhen, X.K. | Deposit date: | 2020-04-20 | Release date: | 2020-09-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.77 Å) | Cite: | Novel polyadenylylation-dependent neutralization mechanism of the HEPN/MNT toxin/antitoxin system. Nucleic Acids Res., 48, 2020
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7CNB
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![BU of 7cnb by Molmil](/molmil-images/mine/7cnb) | |
7WCF
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![BU of 7wcf by Molmil](/molmil-images/mine/7wcf) | Crystal structure of the kinase with AMP-PNP | Descriptor: | HipA_C domain-containing protein, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER | Authors: | Ouyang, S.Y, Zhen, X. | Deposit date: | 2021-12-20 | Release date: | 2022-06-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.3636 Å) | Cite: | Molecular mechanism of toxin neutralization in the HipBST toxin-antitoxin system of Legionella pneumophila. Nat Commun, 13, 2022
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7XVG
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![BU of 7xvg by Molmil](/molmil-images/mine/7xvg) | Cryo-EM structure of binary complex of plant NLR Sr35 and effector AvrSr35 | Descriptor: | AvrSr35, Sr35 | Authors: | Ouyang, S.Y, Zhao, Y.B, Li, Z.K, Liu, M.X. | Deposit date: | 2022-05-23 | Release date: | 2022-09-28 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Pathogen effector AvrSr35 triggers Sr35 resistosome assembly via a direct recognition mechanism. Sci Adv, 8, 2022
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7XX2
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![BU of 7xx2 by Molmil](/molmil-images/mine/7xx2) | Cryo-EM structure of Sr35 resistosome induced by AvrSr35 R381A | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, AvrSr35, CNL9 | Authors: | Ouyang, S.Y, Zhao, Y.B, Li, Z.K, Liu, M.X. | Deposit date: | 2022-05-28 | Release date: | 2022-11-02 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Pathogen effector AvrSr35 triggers Sr35 resistosome assembly via a direct recognition mechanism. Sci Adv, 8, 2022
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7XE0
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![BU of 7xe0 by Molmil](/molmil-images/mine/7xe0) | Cryo-EM structure of plant NLR Sr35 resistosome | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, AvrSr35, Sr35 | Authors: | Ouyang, S.Y, Zhao, Y.B, Li, Z.K, Liu, M.X. | Deposit date: | 2022-03-29 | Release date: | 2022-09-28 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.33 Å) | Cite: | Pathogen effector AvrSr35 triggers Sr35 resistosome assembly via a direct recognition mechanism. Sci Adv, 8, 2022
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7XDS
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![BU of 7xds by Molmil](/molmil-images/mine/7xds) | |
6IM4
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![BU of 6im4 by Molmil](/molmil-images/mine/6im4) | |
6JKY
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![BU of 6jky by Molmil](/molmil-images/mine/6jky) | |
6IST
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![BU of 6ist by Molmil](/molmil-images/mine/6ist) | Crystal structure of a wild type endolysin LysIME-EF1 | Descriptor: | CALCIUM ION, Lysin | Authors: | Ouyang, S.Y. | Deposit date: | 2018-11-19 | Release date: | 2019-11-20 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural and functional insights into a novel two-component endolysin encoded by a single gene in Enterococcus faecalis phage. Plos Pathog., 16, 2020
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6K4L
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6K4R
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![BU of 6k4r by Molmil](/molmil-images/mine/6k4r) | |
6K4K
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![BU of 6k4k by Molmil](/molmil-images/mine/6k4k) | |
8K2E
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![BU of 8k2e by Molmil](/molmil-images/mine/8k2e) | Crystal structure of YTHDC1 and Y3 complex | Descriptor: | 2-chloranyl-6-(4-fluoranylphenoxy)benzoic acid, SULFATE ION, YTH domain-containing protein 1 | Authors: | Zhang, H.L, Yang, S.Y. | Deposit date: | 2023-07-12 | Release date: | 2024-07-17 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | PocketFlow is a data-and-knowledge-driven structure-based molecular generative model Nat. Mach. Intell., 6, 2024
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7C7P
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![BU of 7c7p by Molmil](/molmil-images/mine/7c7p) | Crystal structure of the SARS-CoV-2 main protease in complex with Telaprevir | Descriptor: | (1S,3aR,6aS)-2-[(2S)-2-({(2S)-2-cyclohexyl-2-[(pyrazin-2-ylcarbonyl)amino]acetyl}amino)-3,3-dimethylbutanoyl]-N-[(2R,3S)-1-(cyclopropylamino)-2-hydroxy-1-oxohexan-3-yl]octahydrocyclopenta[c]pyrrole-1-carboxamide, 3C-like proteinase, CHLORIDE ION | Authors: | Zeng, R, Qiao, J.X, Wang, Y.F, Li, Y.S, Yao, R, Yang, S.Y, Lei, J. | Deposit date: | 2020-05-26 | Release date: | 2020-07-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | SARS-CoV-2 M pro inhibitors with antiviral activity in a transgenic mouse model. Science, 371, 2021
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