7TIK
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8FA2
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8FA1
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5HQP
| Crystal structure of the ERp44-peroxiredoxin 4 complex | 分子名称: | Endoplasmic reticulum resident protein 44, Peroxiredoxin-4 | 著者 | Yang, K, Li, D.F, Wang, X, Wang, C.C. | 登録日 | 2016-01-22 | 公開日 | 2016-10-12 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal Structure of the ERp44-Peroxiredoxin 4 Complex Reveals the Molecular Mechanisms of Thiol-Mediated Protein Retention. Structure, 24, 2016
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7JP0
| Crystal structure of Mpro with inhibitor r1 | 分子名称: | 3C-like proteinase, DIMETHYL SULFOXIDE, N-[(benzyloxy)carbonyl]-L-valyl-N-{(2R)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide | 著者 | Yang, K, Liu, W. | 登録日 | 2020-08-07 | 公開日 | 2021-10-13 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Crystal structure of Mpro with inhibitor r1 To Be Published
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6DMX
| HBZ56 in complex with KIX and c-Myb | 分子名称: | BZIP factor, CREB-binding protein, Transcriptional activator Myb | 著者 | Yang, K, Wright, P.E, Stanfield, R.L. | 登録日 | 2018-06-05 | 公開日 | 2018-09-19 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural basis for cooperative regulation of KIX-mediated transcription pathways by the HTLV-1 HBZ activation domain. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6DNQ
| HBZ77 in complex with KIX and c-Myb | 分子名称: | 1,2-ETHANEDIOL, BZIP factor, CREB-binding protein, ... | 著者 | Yang, K, Wright, P.E, Stanfield, R.L. | 登録日 | 2018-06-07 | 公開日 | 2018-09-19 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structural basis for cooperative regulation of KIX-mediated transcription pathways by the HTLV-1 HBZ activation domain. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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7RSM
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5V7Q
| Cryo-EM structure of the large ribosomal subunit from Mycobacterium tuberculosis bound with a potent linezolid analog | 分子名称: | 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | 著者 | Yang, K, Chang, J.-Y, Cui, Z, Zhang, J. | 登録日 | 2017-03-20 | 公開日 | 2017-09-20 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural insights into species-specific features of the ribosome from the human pathogen Mycobacterium tuberculosis. Nucleic Acids Res., 45, 2017
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5V93
| Cryo-EM structure of the 70S ribosome from Mycobacterium tuberculosis bound with Capreomycin | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Yang, K, Chang, J.-Y, Cui, Z, Li, X, Meng, R, Duan, L, Thongchol, J, Jakana, J, Huwe, C, Sacchettini, J, Zhang, J. | 登録日 | 2017-03-22 | 公開日 | 2017-09-20 | 最終更新日 | 2020-08-12 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structural insights into species-specific features of the ribosome from the human pathogen Mycobacterium tuberculosis. Nucleic Acids Res., 45, 2017
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2GTD
| Crystal Structure of a Type III Pantothenate Kinase: Insight into the Catalysis of an Essential Coenzyme A Biosynthetic Enzyme Universally Distributed in Bacteria | 分子名称: | Type III Pantothenate Kinase | 著者 | Yang, K, Eyobo, Y, Brand, A.L, Martynowski, D, Tomchick, D. | 登録日 | 2006-04-27 | 公開日 | 2006-08-01 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure of a Type III Pantothenate Kinase: Insight into the Mechanism of an Essential Coenzyme A Biosynthetic Enzyme Universally Distributed in Bacteria. J.Bacteriol., 188, 2006
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7M2P
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3BF3
| Type III pantothenate kinase from Thermotoga maritima complexed with product phosphopantothenate | 分子名称: | MAGNESIUM ION, N-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanine, Type III pantothenate kinase | 著者 | Yang, K, Huerta, C, Strauss, E, Zhang, H. | 登録日 | 2007-11-20 | 公開日 | 2008-06-24 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | Structural basis for substrate binding and the catalytic mechanism of type III pantothenate kinase. Biochemistry, 47, 2008
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3BEX
| Type III pantothenate kinase from Thermotoga maritima complexed with pantothenate | 分子名称: | PANTOTHENOIC ACID, PHOSPHATE ION, Type III pantothenate kinase | 著者 | Yang, K, Huerta, C, Strauss, E, Zhang, H. | 登録日 | 2007-11-20 | 公開日 | 2008-06-24 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | 主引用文献 | Structural basis for substrate binding and the catalytic mechanism of type III pantothenate kinase. Biochemistry, 47, 2008
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3BF1
| Type III pantothenate kinase from Thermotoga maritima complexed with pantothenate and ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, PANTOTHENOIC ACID, Type III pantothenate kinase | 著者 | Yang, K, Huerta, C, Strauss, E, Zhang, H. | 登録日 | 2007-11-20 | 公開日 | 2008-06-24 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural basis for substrate binding and the catalytic mechanism of type III pantothenate kinase. Biochemistry, 47, 2008
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7JQ2
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7JPY
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7JQ4
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7JQ0
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7JQ1
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7JPZ
| Structure of the SARS-CoV-2 main protease in complex with inhibitor MPI1 | 分子名称: | (phenylmethyl) N-[(2S)-1-oxidanylidene-1-[[(2S)-1-oxidanyl-3-[(3S)-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]amino]-3-phenyl-propan-2-yl]carbamate, 3C-like proteinase | 著者 | Yang, K, Liu, W. | 登録日 | 2020-08-10 | 公開日 | 2020-12-23 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | A Quick Route to Multiple Highly Potent SARS-CoV-2 Main Protease Inhibitors*. Chemmedchem, 16, 2021
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7JQ5
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7JQ3
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5JMT
| Crystal structure of Zika virus NS3 helicase | 分子名称: | NS3 helicase | 著者 | Tian, H, Ji, X, Yang, X, Xie, W, Yang, K, Chen, C, Wu, C, Chi, H, Mu, Z, Wang, Z, Yang, H. | 登録日 | 2016-04-29 | 公開日 | 2016-05-25 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.796 Å) | 主引用文献 | The crystal structure of Zika virus helicase: basis for antiviral drug design Protein Cell, 7, 2016
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1WOF
| Crystal Structure Of SARS-CoV Mpro in Complex with an Inhibitor N1 | 分子名称: | 3C-like proteinase, N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]-L-ALANYL-L-VALYL-N~1~-((1S)-4-ETHOXY-4-OXO-1-{[(3S)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE | 著者 | Yang, H, Bartlam, M, Xue, X, Yang, K, Liang, W, Rao, Z. | 登録日 | 2004-08-18 | 公開日 | 2005-08-30 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases. Plos Biol., 3, 2005
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