7SH8

Structure of the SARS-CoV-2 main protease in complex with inhibitor MPI88

Summary for 7SH8

• Entry DOI: 10.2210/pdb7sh8/pdb
• Descriptor: 3C-like proteinase nsp5, benzyl [(2S,3R)-1-{[(2S)-1-(2-acetyl-2-{[(3S)-2-oxopyrrolidin-3-yl]methyl}hydrazinyl)-3-cyclohexyl-1-oxopropan-2-yl]amino}-3-tert-butoxy-1-oxobutan-2-yl]carbamate (non-preferred name) (3 entities in total)
• Functional Keywords: main protease, viral protein, hydrolase-inhibitor complex, hydrolase/inhibitor
• Biological source: Severe acute respiratory syndrome coronavirus 2
• Total number of polymer chains: 1
• Total formula weight: 34489.31

Authors

Yang, K.S.,Liu, W.R. (deposition date: 2021-10-08, release date: 2023-04-12, Last modification date: 2024-11-20)

• Primary citation: Yang, K.S.,Sankaran, B.,Liu, W.R.; Structure of the SARS-CoV-2 main protease in complex with inhibitors; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.8 Å)