3F49
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![BU of 3f49 by Molmil](/molmil-images/mine/3f49) | |
4DDB
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![BU of 4ddb by Molmil](/molmil-images/mine/4ddb) | EVAL processed HEWL, cisplatin DMSO paratone pH 6.5 | Descriptor: | Cisplatin, DIMETHYL SULFOXIDE, Lysozyme C | Authors: | Tanley, S.W, Schreurs, A.M, Kroon-Batenburg, L.M, Meredith, J, Prendergast, R, Walsh, D, Bryant, P, Levy, C, Helliwell, J.R. | Deposit date: | 2012-01-18 | Release date: | 2012-04-25 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural studies of the effect that dimethyl sulfoxide (DMSO) has on cisplatin and carboplatin binding to histidine in a protein. Acta Crystallogr.,Sect.D, 68, 2012
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7CFW
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![BU of 7cfw by Molmil](/molmil-images/mine/7cfw) | Crystal structure of the receiver domain of sensor histidine kinase PA1611 (PA1611REC) from Pseudomonas aeruginosa PAO1 with calcium ion coordinated in the active site cleft | Descriptor: | CALCIUM ION, Histidine kinase | Authors: | Chen, S.K, Guan, H.H, Wu, P.H, Lin, L.T, Wu, M.C, Chang, H.Y, Chen, N.C, Lin, C.C, Chuankhayan, P, Huang, Y.C, Lin, P.J, Chen, C.J. | Deposit date: | 2020-06-29 | Release date: | 2020-11-04 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.31 Å) | Cite: | Structural insights into the histidine-containing phospho-transfer protein and receiver domain of sensor histidine kinase suggest a complex model in the two-component regulatory system in Pseudomonas aeruginosa Iucrj, 7, 2020
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1LKQ
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![BU of 1lkq by Molmil](/molmil-images/mine/1lkq) | NMR STRUCTURE OF HUMAN INSULIN MUTANT ILE-A2-GLY, VAL-A3-GLY, HIS-B10-ASP, PRO-B28-LYS, LYS-B29-PRO, 20 STRUCTURES | Descriptor: | INSULIN | Authors: | Weiss, M.A, Hua, Q.X, Chu, Y.C, Jia, W, Philips, N.F, Wang, R.Y, Katsoyannis, P.G. | Deposit date: | 2002-04-25 | Release date: | 2002-05-22 | Last modified: | 2021-10-27 | Method: | SOLUTION NMR | Cite: | Mechanism of insulin chain combination. Asymmetric roles of A-chain alpha-helices in disulfide pairing J.Biol.Chem., 277, 2002
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6DCG
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![BU of 6dcg by Molmil](/molmil-images/mine/6dcg) | Discovery of MK-8353: An Orally Bioavailable Dual Mechanism ERK Inhibitor for Oncology | Descriptor: | (3S)-3-(methylsulfanyl)-1-(2-{4-[4-(1-methyl-1H-1,2,4-triazol-3-yl)phenyl]-3,6-dihydropyridin-1(2H)-yl}-2-oxoethyl)-N-(3-{6-[(propan-2-yl)oxy]pyridin-3-yl}-1H-indazol-5-yl)pyrrolidine-3-carboxamide, Mitogen-activated protein kinase 1, SULFATE ION | Authors: | Boga, S.B, Deng, Y, Zhu, L, Nan, Y, Cooper, A, Shipps Jr, G.W, Doll, R, Shih, N, Zhu, H, Sun, R, Wang, T, Paliwal, S, Tsui, H, Gao, X, Yao, X, Desai, J, Wang, J, Alhassan, A.B, Kelly, J, Patel, M, Muppalla, K, Gudipati, S, Zhang, L, Buevich, A, Hesk, D, Carr, D, Dayananth, P, Mei, H, Cox, K, Sherborne, B, Hruza, A.W, Xiao, L, Jin, W, Long, B, Liu, G, Taylor, S.A, Kirschmeier, P, Windsor, W.T, Bishop, R, Samatar, A.A. | Deposit date: | 2018-05-06 | Release date: | 2018-08-08 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | MK-8353: Discovery of an Orally Bioavailable Dual Mechanism ERK Inhibitor for Oncology. ACS Med Chem Lett, 9, 2018
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5YL0
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![BU of 5yl0 by Molmil](/molmil-images/mine/5yl0) | The crystal structure of Penaeus vannamei nodavirus P-domain (P212121) | Descriptor: | Capsid protein | Authors: | Chen, N.C, Yoshimura, M, Lin, C.C, Guan, H.H, Chuankhayan, P, Chen, C.J. | Deposit date: | 2017-10-16 | Release date: | 2018-10-24 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.22 Å) | Cite: | The atomic structures of shrimp nodaviruses reveal new dimeric spike structures and particle polymorphism. Commun Biol, 2, 2019
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5YKX
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![BU of 5ykx by Molmil](/molmil-images/mine/5ykx) | The crystal structure of Macrobrachium rosenbergii nodavirus P-domain with Cd ion | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CADMIUM ION, Capsid protein, ... | Authors: | Chen, N.C, Yoshimura, M, Lin, C.C, Guan, H.H, Chuankhayan, P, Chen, C.J. | Deposit date: | 2017-10-16 | Release date: | 2018-10-24 | Last modified: | 2019-03-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The atomic structures of shrimp nodaviruses reveal new dimeric spike structures and particle polymorphism. Commun Biol, 2, 2019
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5YKZ
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![BU of 5ykz by Molmil](/molmil-images/mine/5ykz) | The crystal structure of Penaeus vannamei nodavirus P-domain (P21) | Descriptor: | Capsid protein | Authors: | Chen, N.C, Yoshimura, M, Lin, C.C, Guan, H.H, Chuankhayan, P, Chen, C.J. | Deposit date: | 2017-10-16 | Release date: | 2018-10-24 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.17 Å) | Cite: | The atomic structures of shrimp nodaviruses reveal new dimeric spike structures and particle polymorphism. Commun Biol, 2, 2019
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5YKV
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![BU of 5ykv by Molmil](/molmil-images/mine/5ykv) | The crystal structure of Macrobrachium rosenbergii nodavirus P-domain | Descriptor: | Capsid protein | Authors: | Chen, N.C, Yoshimura, M, Lin, C.C, Guan, H.H, Chuankhayan, P, Chen, C.J. | Deposit date: | 2017-10-16 | Release date: | 2018-10-24 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | The atomic structures of shrimp nodaviruses reveal new dimeric spike structures and particle polymorphism. Commun Biol, 2, 2019
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5YKU
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![BU of 5yku by Molmil](/molmil-images/mine/5yku) | The crystal structure of Macrobrachium rosenbergii nodavirus P-domain with Zn ions | Descriptor: | Capsid protein, ZINC ION | Authors: | Chen, N.C, Yoshimura, M, Lin, C.C, Guan, H.H, Chuankhayan, P, Chen, C.J. | Deposit date: | 2017-10-16 | Release date: | 2018-10-24 | Last modified: | 2019-03-13 | Method: | X-RAY DIFFRACTION (1.39 Å) | Cite: | The atomic structures of shrimp nodaviruses reveal new dimeric spike structures and particle polymorphism. Commun Biol, 2, 2019
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7XPD
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![BU of 7xpd by Molmil](/molmil-images/mine/7xpd) | Cryo-EM structure of the T=3 lake sinai virus 2 virus-like capsid at pH 6.5 | Descriptor: | Capsid protein alpha | Authors: | Chen, N.C, Wang, C.H, Chen, C.J, Yoshimura, M, Guan, H.H, Chuankhayan, P, Lin, C.C. | Deposit date: | 2022-05-04 | Release date: | 2023-02-08 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.74 Å) | Cite: | Structures of honeybee-infecting Lake Sinai virus reveal domain functions and capsid assembly with dynamic motions. Nat Commun, 14, 2023
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7XPF
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![BU of 7xpf by Molmil](/molmil-images/mine/7xpf) | Cryo-EM structure of the T=3 lake sinai virus 2 virus-like capsid at pH 8.5 | Descriptor: | Capsid protein alpha | Authors: | Chen, N.C, Wang, C.H, Chen, C.J, Yoshimura, M, Guan, H.H, Chuankhayan, P, Lin, C.C. | Deposit date: | 2022-05-04 | Release date: | 2023-02-08 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.13 Å) | Cite: | Structures of honeybee-infecting Lake Sinai virus reveal domain functions and capsid assembly with dynamic motions. Nat Commun, 14, 2023
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1K3M
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![BU of 1k3m by Molmil](/molmil-images/mine/1k3m) | NMR STRUCTURE OF HUMAN INSULIN MUTANT ILE-A2-ALA, HIS-B10-ASP, PRO-B28-LYS, LYS-B29-PRO, 15 STRUCTURES | Descriptor: | INSULIN | Authors: | Xu, B, Hua, Q.-X, Nakagawa, S.H, Jia, W, Chu, Y.-C, Katsoyannis, P.G, Weiss, M.A. | Deposit date: | 2001-10-03 | Release date: | 2001-10-17 | Last modified: | 2021-10-27 | Method: | SOLUTION NMR | Cite: | A cavity-forming mutation in insulin induces segmental unfolding of a surrounding alpha-helix. Protein Sci., 11, 2002
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1KN6
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1DY3
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![BU of 1dy3 by Molmil](/molmil-images/mine/1dy3) | Ternary complex of 7,8-dihydro-6-hydroxymethylpterinpyrophosphokinase from Escherichia coli with ATP and a substrate analogue. | Descriptor: | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, 7,8-DIHYDRO-6-HYDROXYMETHYL-7-METHYL-7-[2-PHENYLETHYL]-PTERIN, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Stammers, D.K, Achari, A, Somers, D.O, Bryant, P.K, Rosemond, J, Scott, D.L, Champness, J.N. | Deposit date: | 2000-01-21 | Release date: | 2000-08-18 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | 2.0A X-Ray Structure of the Ternary Complex of 7,8-Dihydro-6-Hydroxymethylpterinpyrophosphokinase from Escherichia Coli with ATP and a Substrate Analogue FEBS Lett., 456, 1999
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1SJU
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![BU of 1sju by Molmil](/molmil-images/mine/1sju) | MINI-PROINSULIN, SINGLE CHAIN INSULIN ANALOG MUTANT: DES B30, HIS(B 10)ASP, PRO(B 28)ASP AND PEPTIDE BOND BETWEEN LYS B 29 AND GLY A 1, NMR, 20 STRUCTURES | Descriptor: | PROINSULIN | Authors: | Hua, Q.X, Hu, S.Q, Jia, W.H, Chu, Y.C, Burke, G.T, Wang, S.H, Katsoyannis, P.G, Weiss, M.A. | Deposit date: | 1997-10-09 | Release date: | 1998-03-18 | Last modified: | 2021-11-03 | Method: | SOLUTION NMR | Cite: | Mini-proinsulin and mini-IGF-I: homologous protein sequences encoding non-homologous structures. J.Mol.Biol., 277, 1998
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1DYR
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![BU of 1dyr by Molmil](/molmil-images/mine/1dyr) | THE STRUCTURE OF PNEUMOCYSTIS CARINII DIHYDROFOLATE REDUCTASE TO 1.9 ANGSTROMS RESOLUTION | Descriptor: | DIHYDROFOLATE REDUCTASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, TRIMETHOPRIM | Authors: | Champness, J.N, Achari, A, Ballantine, S.P, Bryant, P.K, Delves, C.J, Stammers, D.K. | Deposit date: | 1994-09-14 | Release date: | 1995-10-15 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | The structure of Pneumocystis carinii dihydrofolate reductase to 1.9 A resolution. Structure, 2, 1994
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5YL1
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![BU of 5yl1 by Molmil](/molmil-images/mine/5yl1) | T=1 subviral particle of Penaeus vannamei nodavirus capsid protein deletion mutant (delta 1-37 & 251-368) | Descriptor: | CALCIUM ION, Capsid protein | Authors: | Chen, N.C, Yoshimura, M, Lin, C.C, Guan, H.H, Chuankhayan, P, Chen, C.J. | Deposit date: | 2017-10-16 | Release date: | 2018-12-12 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (3.12 Å) | Cite: | The atomic structures of shrimp nodaviruses reveal new dimeric spike structures and particle polymorphism. Commun Biol, 2, 2019
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1SJT
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![BU of 1sjt by Molmil](/molmil-images/mine/1sjt) | MINI-PROINSULIN, TWO CHAIN INSULIN ANALOG MUTANT: DES B30, HIS(B 10)ASP, PRO(B 28)ASP, NMR, 20 STRUCTURES | Descriptor: | PROINSULIN | Authors: | Hua, Q.X, Hu, S.Q, Jia, W.H, Chu, Y.C, Burke, G.T, Wang, S.H, Katsoyannis, P.G, Weiss, M.A. | Deposit date: | 1997-10-09 | Release date: | 1998-03-18 | Last modified: | 2021-11-03 | Method: | SOLUTION NMR | Cite: | Mini-proinsulin and mini-IGF-I: homologous protein sequences encoding non-homologous structures. J.Mol.Biol., 277, 1998
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7XPE
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![BU of 7xpe by Molmil](/molmil-images/mine/7xpe) | Cryo-EM structure of the T=4 lake sinai virus 2 virus-like capsid at pH 8.5 | Descriptor: | Capsid protein alpha | Authors: | Chen, N.C, Wang, C.H, Chen, C.J, Yoshimura, M, Guan, H.H, Chuankhayan, P, Lin, C.C. | Deposit date: | 2022-05-04 | Release date: | 2023-02-08 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.32 Å) | Cite: | Structures of honeybee-infecting Lake Sinai virus reveal domain functions and capsid assembly with dynamic motions. Nat Commun, 14, 2023
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7XGZ
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![BU of 7xgz by Molmil](/molmil-images/mine/7xgz) | Cryo-EM structure of the T=4 lake sinai virus 2 virus-like capsid at pH 7.5 | Descriptor: | Capsid protein alpha | Authors: | Chen, N.C, Wang, C.H, Chen, C.J, Yoshimura, M, Guan, H.H, Chuankhayan, P, Lin, C.C. | Deposit date: | 2022-04-07 | Release date: | 2023-02-08 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.24 Å) | Cite: | Structures of honeybee-infecting Lake Sinai virus reveal domain functions and capsid assembly with dynamic motions Nat Commun, 14, 2023
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7XPA
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![BU of 7xpa by Molmil](/molmil-images/mine/7xpa) | Cryo-EM structure of the T=3 lake sinai virus 2 virus-like capsid at pH 7.5 | Descriptor: | Capsid protein alpha | Authors: | Chen, N.C, Wang, C.H, Chen, C.J, Yoshimura, M, Guan, H.H, Chuankhayan, P, Lin, C.C. | Deposit date: | 2022-05-04 | Release date: | 2023-02-08 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.33 Å) | Cite: | Structures of honeybee-infecting Lake Sinai virus reveal domain functions and capsid assembly with dynamic motions. Nat Commun, 14, 2023
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7XPB
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![BU of 7xpb by Molmil](/molmil-images/mine/7xpb) | Cryo-EM structure of the T=4 lake sinai virus 2 virus-like capsid at pH 6.5 | Descriptor: | Capsid protein alpha | Authors: | Chen, N.C, Wang, C.H, Chen, C.J, Yoshimura, M, Guan, H.H, Chuankhayan, P, Lin, C.C. | Deposit date: | 2022-05-04 | Release date: | 2023-02-08 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.91 Å) | Cite: | Structures of honeybee-infecting Lake Sinai virus reveal domain functions and capsid assembly with dynamic motions. Nat Commun, 14, 2023
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7LC9
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2LHG
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![BU of 2lhg by Molmil](/molmil-images/mine/2lhg) | GB98-T25I solution structure | Descriptor: | GB98 | Authors: | He, Y, Chen, Y, Alexander, P, Bryan, P, Orban, J. | Deposit date: | 2011-08-08 | Release date: | 2012-02-29 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Mutational tipping points for switching protein folds and functions. Structure, 20, 2012
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