Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 904 results

3QML
DownloadVisualize
BU of 3qml by Molmil
The structural analysis of Sil1-Bip complex reveals the mechanism for Sil1 to function as a novel nucleotide exchange factor
Descriptor: 78 kDa glucose-regulated protein homolog, MAGNESIUM ION, Nucleotide exchange factor SIL1, ...
Authors:Yan, M, Li, J.Z, Sha, B.D.
Deposit date:2011-02-04
Release date:2011-06-29
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Structural analysis of the Sil1-Bip complex reveals the mechanism for Sil1 to function as a nucleotide-exchange factor.
Biochem.J., 438, 2011
3QFU
DownloadVisualize
BU of 3qfu by Molmil
Crystal structure of Yeast Hsp70 (Bip/kar2) complexed with ADP
Descriptor: 78 kDa glucose-regulated protein homolog, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Yan, M, Li, J.Z, Sha, B.D.
Deposit date:2011-01-22
Release date:2011-06-29
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural analysis of the Sil1-Bip complex reveals the mechanism for Sil1 to function as a nucleotide-exchange factor.
Biochem.J., 438, 2011
3QFP
DownloadVisualize
BU of 3qfp by Molmil
Crystal structure of yeast Hsp70 (Bip/Kar2) ATPase domain
Descriptor: 78 kDa glucose-regulated protein homolog, PHOSPHATE ION
Authors:Yan, M, Li, J.Z, Sha, B.D.
Deposit date:2011-01-22
Release date:2011-06-29
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Structural analysis of the Sil1-Bip complex reveals the mechanism for Sil1 to function as a nucleotide-exchange factor.
Biochem.J., 438, 2011
8IQU
DownloadVisualize
BU of 8iqu by Molmil
Structure of MtbFadD23 with PhU-AMS
Descriptor: 5'-O-[(11-phenoxyundecanoyl)sulfamoyl]adenosine, Fatty-acid-CoA ligase FadD23
Authors:Yan, M.R, Zhang, W.
Deposit date:2023-03-17
Release date:2023-04-26
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Structural basis for the development of potential inhibitors targeting FadD23 from Mycobacterium tuberculosis.
Acta Crystallogr.,Sect.F, 79, 2023
8HCZ
DownloadVisualize
BU of 8hcz by Molmil
N-terminal domain structure of mycobacterium tuberculosis FadD23
Descriptor: Long-chain-fatty-acid--AMP ligase FadD23
Authors:Yan, M.R, Liu, X, Zhang, W, Rao, Z.H.
Deposit date:2022-11-03
Release date:2023-02-15
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:The Key Roles of Mycobacterium tuberculosis FadD23 C-terminal Domain in Catalytic Mechanisms.
Front Microbiol, 14, 2023
8HDF
DownloadVisualize
BU of 8hdf by Molmil
Full length crystal structure of mycobacterium tuberculosis FadD23 in complex with ANP and PLM
Descriptor: Long-chain-fatty-acid--AMP ligase FadD23, PALMITIC ACID, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Yan, M.R, Liu, X, Zhang, W, Rao, Z.H.
Deposit date:2022-11-04
Release date:2023-02-15
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:The Key Roles of Mycobacterium tuberculosis FadD23 C-terminal Domain in Catalytic Mechanisms.
Front Microbiol, 14, 2023
8HD4
DownloadVisualize
BU of 8hd4 by Molmil
Full-length crystal structure of mycobacterium tuberculosis FadD23 in complex with AMPC16
Descriptor: Long-chain-fatty-acid--AMP ligase FadD23, palmitoyl adenylate
Authors:Yan, M.R, Liu, X, Zhang, W, Rao, Z.H.
Deposit date:2022-11-03
Release date:2023-02-15
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:The Key Roles of Mycobacterium tuberculosis FadD23 C-terminal Domain in Catalytic Mechanisms.
Front Microbiol, 14, 2023
8HEF
DownloadVisualize
BU of 8hef by Molmil
The Crystal structure of deuterated S-217622 (Ensitrelvir) bound to the main protease (3CLpro/Mpro) of SARS-CoV-2
Descriptor: 3C-like proteinase, 6-[(6-chloranyl-2-methyl-indazol-5-yl)amino]-3-[(1-methyl-1,2,4-triazol-3-yl)methyl]-1-[[2,4,5-tris(fluoranyl)phenyl]methyl]-1,3,5-triazine-2,4-dione, GLYCEROL
Authors:Yan, M, Zhang, H.
Deposit date:2022-11-08
Release date:2023-04-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Synthesis of deuterated S-217622 (Ensitrelvir) with antiviral activity against coronaviruses including SARS-CoV-2.
Antiviral Res., 213, 2023
5WY5
DownloadVisualize
BU of 5wy5 by Molmil
Crystal structure of MAGEG1 and NSE1 complex
Descriptor: MAGNESIUM ION, Melanoma-associated antigen G1, Non-structural maintenance of chromosomes element 1 homolog, ...
Authors:Yang, M, Gao, J.
Deposit date:2017-01-11
Release date:2017-05-03
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.92 Å)
Cite:Mage-Ring Protein Complexes Comprise A Family Of E3 Ubiquitin Ligases.
Mol.Cell, 39, 2010
1HV2
DownloadVisualize
BU of 1hv2 by Molmil
SOLUTION STRUCTURE OF YEAST ELONGIN C IN COMPLEX WITH A VON HIPPEL-LINDAU PEPTIDE
Descriptor: ELONGIN C, VON HIPPEL-LINDAU DISEASE TUMOR SUPPRESSOR
Authors:Botuyan, M.V, Mer, G, Yi, G.-S, Koth, C.M, Case, D.A, Edwards, A.M, Chazin, W.J, Arrowsmith, C.H.
Deposit date:2001-01-05
Release date:2001-09-06
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure and dynamics of yeast elongin C in complex with a von Hippel-Lindau peptide.
J.Mol.Biol., 312, 2001
1QI9
DownloadVisualize
BU of 1qi9 by Molmil
X-RAY SIRAS STRUCTURE DETERMINATION OF A VANADIUM-DEPENDENT HALOPEROXIDASE FROM ASCOPHYLLUM NODOSUM AT 2.0 A RESOLUTION
Descriptor: VANADATE ION, Vanadium-dependent bromoperoxidase
Authors:Weyand, M, Hecht, H.-J, Kiess, M, Liaud, M.F, Vilter, H, Schomburg, D.
Deposit date:1999-06-10
Release date:2000-06-10
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:X-ray structure determination of a vanadium-dependent haloperoxidase from Ascophyllum nodosum at 2.0 A resolution.
J.Mol.Biol., 293, 1999
1QOP
DownloadVisualize
BU of 1qop by Molmil
CRYSTAL STRUCTURE OF WILD-TYPE TRYPTOPHAN SYNTHASE COMPLEXED WITH INDOLE PROPANOL PHOSPHATE
Descriptor: INDOLE-3-PROPANOL PHOSPHATE, PYRIDOXAL-5'-PHOSPHATE, SODIUM ION, ...
Authors:Weyand, M, Schlichting, I.
Deposit date:1999-11-15
Release date:2000-11-10
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal Structure of Wild-Type Tryptophan Synthase Complexed with the Natural Substrate Indole-3-Glycerol Phosphate
Biochemistry, 38, 1999
1QOQ
DownloadVisualize
BU of 1qoq by Molmil
CRYSTAL STRUCTURE OF WILD-TYPE TRYPTOPHAN SYNTHASE COMPLEXED WITH INDOLE GLYCEROL PHOSPHATE
Descriptor: INDOLE-3-GLYCEROL PHOSPHATE, PYRIDOXAL-5'-PHOSPHATE, TRYPTOPHAN SYNTHASE ALPHA CHAIN, ...
Authors:Weyand, M, Schlichting, I.
Deposit date:1999-11-15
Release date:2000-11-10
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of Wild-Type Tryptophan Synthase Complexed with the Natural Substrate Indole-3-Glycerol Phosphate.
Biochemistry, 38, 1999
6PIK
DownloadVisualize
BU of 6pik by Molmil
Tetrameric cryo-EM ArnA
Descriptor: Bifunctional polymyxin resistance protein ArnA, UDP-4-amino-4-deoxy-L-arabinose formyltransferase
Authors:Yang, M, Gehring, K.
Deposit date:2019-06-26
Release date:2019-07-31
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (7.8 Å)
Cite:Cryo-electron microscopy structures of ArnA, a key enzyme for polymyxin resistance, revealed unexpected oligomerizations and domain movements.
J.Struct.Biol., 208, 2019
6PIH
DownloadVisualize
BU of 6pih by Molmil
Hexameric ArnA cryo-EM structure
Descriptor: Bifunctional polymyxin resistance protein ArnA, UDP-4-amino-4-deoxy-L-arabinose formyltransferase
Authors:Yang, M, Gehring, K.
Deposit date:2019-06-26
Release date:2019-07-31
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (6.6 Å)
Cite:Cryo-electron microscopy structures of ArnA, a key enzyme for polymyxin resistance, revealed unexpected oligomerizations and domain movements.
J.Struct.Biol., 208, 2019
6G32
DownloadVisualize
BU of 6g32 by Molmil
Crystal structure of human geranylgeranyl diphosphate synthase mutant D188Y
Descriptor: GLYCEROL, Geranylgeranyl pyrophosphate synthase
Authors:Lisnyansky, M, Kapelushnik, N, Ben-Bassat, A, Marom, M, Loewenstein, A, Khananshvili, D, Giladi, M, Haitin, Y.
Deposit date:2018-03-24
Release date:2018-10-17
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.281 Å)
Cite:Reduced Activity of Geranylgeranyl Diphosphate Synthase Mutant Is Involved in Bisphosphonate-Induced Atypical Fractures.
Mol. Pharmacol., 94, 2018
6G31
DownloadVisualize
BU of 6g31 by Molmil
Crystal structure of human geranylgeranyl diphosphate synthase mutant D188Y bound to zoledronate
Descriptor: Geranylgeranyl pyrophosphate synthase, MAGNESIUM ION, ZOLEDRONIC ACID
Authors:Lisnyansky, M, Kapelushnik, N, Ben-Bassat, A, Marom, M, Loewenstein, A, Khananshvili, D, Giladi, M, Haitin, Y.
Deposit date:2018-03-24
Release date:2018-10-17
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3 Å)
Cite:Reduced Activity of Geranylgeranyl Diphosphate Synthase Mutant Is Involved in Bisphosphonate-Induced Atypical Fractures.
Mol. Pharmacol., 94, 2018
7OJY
DownloadVisualize
BU of 7ojy by Molmil
Crystal structure of Pseudomonas aeruginosa LpxA in complex with compound 6
Descriptor: 2-(2-chlorophenyl)sulfanyl-~{N}-[(4-cyanophenyl)methyl]-~{N}-[(5-oxidanyl-1,3,4-oxadiazol-2-yl)methyl]ethanamide, Acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase, CHLORIDE ION
Authors:Ryan, M.D, Parkes, A.L, Southey, M, Andersen, O.A, Zahn, M, Barker, J, DeJonge, B.L.M.
Deposit date:2021-05-17
Release date:2021-10-06
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:Discovery of Novel UDP- N -Acetylglucosamine Acyltransferase (LpxA) Inhibitors with Activity against Pseudomonas aeruginosa .
J.Med.Chem., 64, 2021
7OKB
DownloadVisualize
BU of 7okb by Molmil
Crystal structure of Pseudomonas aeruginosa LpxA in complex with compound 45
Descriptor: Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, CHLORIDE ION, SULFATE ION, ...
Authors:Ryan, M.D, Parkes, A.L, Southey, M, Andersen, O.A, Zahn, M, Barker, J, DeJonge, B.L.M.
Deposit date:2021-05-17
Release date:2021-10-06
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.58 Å)
Cite:Discovery of Novel UDP- N -Acetylglucosamine Acyltransferase (LpxA) Inhibitors with Activity against Pseudomonas aeruginosa .
J.Med.Chem., 64, 2021
7OKC
DownloadVisualize
BU of 7okc by Molmil
Crystal structure of Escherichia coli LpxA in complex with compound 1
Descriptor: 2-[2-(2-chlorophenyl)sulfanylethanoyl-[[4-(1,2,4-triazol-1-yl)phenyl]methyl]amino]-N-methyl-ethanamide, Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, SODIUM ION
Authors:Ryan, M.D, Parkes, A.L, Southey, M, Andersen, O.A, Zahn, M, Barker, J, DeJonge, B.L.M.
Deposit date:2021-05-17
Release date:2021-10-06
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Discovery of Novel UDP- N -Acetylglucosamine Acyltransferase (LpxA) Inhibitors with Activity against Pseudomonas aeruginosa .
J.Med.Chem., 64, 2021
7OJP
DownloadVisualize
BU of 7ojp by Molmil
Crystal structure of Pseudomonas aeruginosa LpxA in complex with compound 1
Descriptor: 2-[2-(2-chlorophenyl)sulfanylethanoyl-[[4-(1,2,4-triazol-1-yl)phenyl]methyl]amino]-N-methyl-ethanamide, Acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase, MAGNESIUM ION
Authors:Ryan, M.D, Parkes, A.L, Southey, M, Andersen, O.A, Zahn, M, Barker, J, DeJonge, B.L.M.
Deposit date:2021-05-17
Release date:2021-10-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:Discovery of Novel UDP- N -Acetylglucosamine Acyltransferase (LpxA) Inhibitors with Activity against Pseudomonas aeruginosa .
J.Med.Chem., 64, 2021
7OK1
DownloadVisualize
BU of 7ok1 by Molmil
Crystal structure of Pseudomonas aeruginosa LpxA in complex with compound 3
Descriptor: Acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase, CHLORIDE ION, ~{N}-[(5-azanyl-1,3,4-oxadiazol-2-yl)methyl]-2-(2-chlorophenyl)sulfanyl-~{N}-[(4-cyanophenyl)methyl]ethanamide
Authors:Ryan, M.D, Parkes, A.L, Southey, M, Andersen, O.A, Zahn, M, Barker, J, DeJonge, B.L.M.
Deposit date:2021-05-17
Release date:2021-10-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Discovery of Novel UDP- N -Acetylglucosamine Acyltransferase (LpxA) Inhibitors with Activity against Pseudomonas aeruginosa .
J.Med.Chem., 64, 2021
7OJ6
DownloadVisualize
BU of 7oj6 by Molmil
Crystal structure of Pseudomonas aeruginosa LpxA in complex with compound 1
Descriptor: 2-[2-(2-chlorophenyl)sulfanylethanoyl-[[4-(1,2,4-triazol-1-yl)phenyl]methyl]amino]-N-methyl-ethanamide, ACETATE ION, Acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase, ...
Authors:Ryan, M.D, Parkes, A.L, Southey, M, Andersen, O.A, Zahn, M, Barker, J, DeJonge, B.L.M.
Deposit date:2021-05-14
Release date:2021-10-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Discovery of Novel UDP- N -Acetylglucosamine Acyltransferase (LpxA) Inhibitors with Activity against Pseudomonas aeruginosa .
J.Med.Chem., 64, 2021
7OKA
DownloadVisualize
BU of 7oka by Molmil
Crystal structure of Pseudomonas aeruginosa LpxA in complex with compound 14
Descriptor: 2-(2-chlorophenyl)sulfanyl-~{N}-[(4-cyanophenyl)methyl]-~{N}-(1~{H}-imidazol-4-ylmethyl)ethanamide, Acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase, CHLORIDE ION, ...
Authors:Ryan, M.D, Parkes, A.L, Southey, M, Andersen, O.A, Zahn, M, Barker, J, DeJonge, B.L.M.
Deposit date:2021-05-17
Release date:2021-10-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:Discovery of Novel UDP- N -Acetylglucosamine Acyltransferase (LpxA) Inhibitors with Activity against Pseudomonas aeruginosa .
J.Med.Chem., 64, 2021
7OJQ
DownloadVisualize
BU of 7ojq by Molmil
Crystal structure of Pseudomonas aeruginosa LpxA in complex with compound 7
Descriptor: 2-(2-chlorophenyl)sulfanyl-~{N}-[(4-cyanophenyl)methyl]-~{N}-[(5-methyl-1,3,4-oxadiazol-2-yl)methyl]ethanamide, Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase
Authors:Ryan, M.D, Parkes, A.L, Southey, M, Andersen, O.A, Zahn, M, Barker, J, DeJonge, B.L.M.
Deposit date:2021-05-17
Release date:2021-10-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Discovery of Novel UDP- N -Acetylglucosamine Acyltransferase (LpxA) Inhibitors with Activity against Pseudomonas aeruginosa .
J.Med.Chem., 64, 2021

226707

数据于2024-10-30公开中

PDB statisticsPDBj update infoContact PDBjnumon